2019
- Al-Shehabi H, Fiebig U, Kutzner J, Denner J, Schaller T, Bannert N, Hofmann H. Human SAMHD1 restricts the xenotransplantation relevant porcine endogenous retrovirus (perv) in non-dividing cells. Journal of General Virology DOI 10.1099/jgv.0.001232
- Bakhti M, Böttcher A, Lickert H. Modelling the endocrine pancreas in health and disease. Nat Rev Endocrinol. Mar;15(3):155-171. doi: 10.1038/s41574-018-0132-z. Review.
- Denner J, Bigley TM, Phan TL, Zimmermann C, Zhou X, Kaufer BB. Comparative Analysis of Roseoloviruses in Humans, Pigs, Mice, and Other Species. Viruses. Nov 30;11(12). pii: E1108. doi: 10.3390/v11121108. Review.
- Denner J, Pischke S, Steinmann E, Blümel J, Glebe D. Why all blood donations should be tested for hepatitis E virus (HEV). BMC Infect Dis. Jun 20;19(1):541. doi: 10.1186/s12879-019-4190-1.
- Denner J. Hepatitis E virus (HEV)-The Future. Viruses. Mar 13;11(3). pii: E251. doi: 10.3390/v11030251.
- Denner J, Scobie L. Are there better assays to evaluate the risk of transmission of porcine endogenous retroviruses (PERVs) to human cells? Xenotransplantation. e12510. DOI: 10.1111/xen.12510
- Duin S, Schütz K, Ahlfeld T, Lehmann S, Lode A, Ludwig B, Gelinsky M. 3D Bioprinting of Functional Islets of Langerhans in an Alginate/Methylcellulose Hydrogel Blend. Adv Healthc Mater. Apr;8(7):e1801631. doi: 10.1002/adhm.201801631. Epub 2019 Mar 5.
- Figueiredo C, Carvalho Oliveira M, Chen-Wacker C, Jansson K, Höffler K, Yuzefovych Y, Pogozhykh O, Jin Z, Kühnel M, Jonigk D, Wiegmann B, Sommer W, Haverich A, Warnecke G, Blasczyk R. Immunoengineering of the Vascular Endothelium to Silence MHC Expression During Normothermic Ex Vivo Lung Perfusion. Hum Gene Ther. Apr;30(4):485-496. doi: 10.1089/hum.2018.117. Epub 2018 Nov 20
- Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, Chen ACH, Eckersley-Maslin MA, Ahmad S, Lee YL, Kobayashi T, Ryan D, Zhong J, Zhu J, Wu J, Lan G, Petkov S, Yang J, Antunes L, Campos LS, Fu B, Wang S, Yong Y, Wang X, Xue SG, Ge L, Liu Z, Huang Y, Nie T, Li P, Wu D, Pei D, Zhang Y, Lu L, Yang F, Kimber SJ, Reik W, Zou X, Shang Z, Lai L, Surani A, Tam PPL, Ahmed A, Yeung WSB, Teichmann SA, Niemann H, Liu P. Establishment of porcine and human expanded potential stem cells. Nat Cell Biol. Jun;21(6):687-699. doi: 10.1038/s41556-019-0333-2. Epub 2019 Jun 3.
- Godehardt AW, Fischer N, Rauch P, Gulich B, Boller K, Church GM, Tönjes RR. Characterization of porcine endogenous retrovirus particles released by the CRISPR/Cas9 inactivated cell line PK15 clone 15. Xenotransplantation. Oct 31:e12563. doi: 10.1111/xen.12563. Epub Okt 31
- Godehardt AW, Ramm R, Gulich B, Tönjes RR, Hilfiker A. Decellularized pig pulmonary heart valves-Depletion of nucleic acids measured by proviral PERV pol. Xenotransplantation. Nov 6:e12565. doi: 10.1111/xen.12565. Epub Nov 6
- Hajishengallis G, Chavakis T. DEL-1-Regulated Immune Plasticity and Inflammatory Disorders. Trends Mol Med. May;25(5):444-459. doi: 10.1016/j.molmed.2019.02.010. Epub 2019 Mar 15. Review.
- Hein R, Sake HJ, Pokoyski C, Hundrieser J, Brinkmann A, Baars W, Nowak-Imialek M, Lucas-Hahn A, Figueiredo C, Schuberth HJ, Niemann H, Petersen B, Schwinzer R. Triple (GGTA1, CMAH, B2M) modified pigs expressing an SLA class-Ilow phenotype - effects on immune status and susceptibility to human immune responses. Am J Transplant. Nov 15. doi: 10.1111/ajt.15710. Epub Dez 28
- Hermann L, Hoppe N, Kahrass H, Lohse S, Mertz M, Pietschmann I. How Ethics, Law and Philosophy of Science Can Help Make Progress in the Development and Use of Alternative Methods, In: ALTEX - Alternatives to Animal Experimentation, 36(4): 68
- Hoppe N. Germany: Country Report; Legal and Ethical Challenges of International Direct-to-Participant Genomic Research. Journal of Law, Medicine & Ethics 47, no. 4, 615-619
- Hundrieser J, Hein R, Pokoyski C, Brinkmann A, Düvel H, Dinkel A, Trautewig B, Siegert JF, Römermann D, Petersen B, Schwinzer R. Role of human and porcine MHC DRB1 alleles in determining the intensity of individual human anti-pig T-cell responses. Xenotransplantation. May 9:e12523. doi: 10.1111/xen.12523. Epub May 9
- Jacome-Galarza CE, Percin GI, Muller JT, Mass E, Lazarov T, Eitler J, Rauner M, Yadav VK, Crozet L, Bohm M, Loyher PL, Karsenty G, Waskow C , Geissmann F. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature 568(7753):541-545. doi: 10.1038/s41586-019-1105-7. Epub Apr 10.
- Katsimpoulas M, Morticelli L, Gontika I, Kouvaka A, Mallis P, Dipresa D, Böer U, Soudah B, Haverich A, Michalopoulos E, Korossis S. Biocompatibility and Immunogenicity of Decellularised Allogeneic Aorta in the Orthotopic Rat Model. Tissue Eng Part A. Mar;25(5-6):399-415.
- Keubler LM, Hoppe N, Potschka H, Talbot SR, Vollmar B, Zechner D, Häger C, Bleich A. Where are we heading? Challenges in evidence-based severity assessment. Lab Anim. Feb;54(1):50-62. doi: 10.1177/0023677219877216. Epub 2019 Nov 13
- Kola I, Egerer S, Bähr A, Godehardt AW, Tönjes RR, Ayares D, Wolf E, Klymiuk N. Removal of PERV- C proviruses from xenotransplanation donor pigs by marker-assisted breeding or gene editing. Xenotransplantation 2019;xen12553 [Abstract]
- Kourtzelis I, Li X, Mitroulis I, Grosser D, Kajikawa T, Wang B, Grzybek M, von Renesse J, Czogalla A, Troullinaki M, Ferreira A, Doreth C, Ruppova K, Chen LS, Hosur K, Lim JH, Chung KJ, Grossklaus S, Tausche AK, Joosten LAB, Moutsopoulos NM, Wielockx B, Castrillo A, Korostoff JM, Coskun Ü, Hajishengallis G, Chavakis T. DEL-1 promotes macrophage efferocytosis and clearance of inflammation. Nat Immunol. Jan;20(1):40-49. doi: 10.1038/s41590-018-0249-1. Epub 2018 Nov 19.
- Krüger L, Längin M, Reichart B, Fiebig U, Kristiansen Y, Prinz C, Kessler B, Egerer S, Wolf E, Abicht JM, Denner J. Transmission of Porcine Circovirus 3 (PCV3) by Xenotransplantation of Pig Hearts into Baboons. Viruses. Jul 16;11(7). pii: E650. doi: 10.3390/v11070650.
- Krüger L, Kristiansen Y, Reuber E, Möller L, Laue M, Reimer C, Denner, J. A Comprehensive Strategy for Screening for Xenotransplantation-Relevant Viruses in a Second Isolated Population of Göttingen Minipigs. Viruses 2019;[revision submitted]
- Kurome M, Baehr A, Simmet K, Jemiller EM, Egerer S, Dahlhoff M, Zakhartchenko V, Nagashima H, Klymiuk N, Kessler B, Wolf E. Targeting αGal epitopes for multi-species embryo immunosurgery. Reprod Fertil Dev.;31(4):820-826
- Lohse S, Bschir K, Chang H. (Gast-Hg.) Systematicity: The Nature of Science? (Synthese - Special Issue: 196(3))
- Mederacke YS, Vondran FW, Kollrich S, Schulde E, Schmitt R, Manns MP, Klempnauer J, Schwinzer R, Noyan F, Jaeckel E. Transient increase of activated regulatory T cells early after kidney transplantation. Sci Rep. Jan 31;9(1):1021. doi: 10.1038/s41598-018-37218-x.
- Pape S, Gevers TJG, Belias M, Mustafajev IF, Vrolijk JM, van Hoek B, Bouma G, van Nieuwkerk CMJ, Hartl J, Schramm C, Lohse AW, Taubert R, Jaeckel E, Manns MP, Papp M, Stickel F, Heneghan MA, Drenth JPH. Predniso(lo)ne Dosage and Chance of Remission in Patients With Autoimmune Hepatitis. Clin Gastroenterol Hepatol. Jan 6. pii: S1542-3565(19)30008-4. doi: 10.1016/j.cgh.2018.12.035. Epub Jan. 6
- Prinz C, Stillfried M, Neubert LK, Denner J. Detection of PCV3 in German wild boars. Virol J. Feb 22;16(1):25. doi: 10.1186/s12985-019-1133-9.
- Ramm R, Goecke T, Theodoridis K, Hoeffler K, Sarikouch S, Findeisen K, Ciubotaru A, Cebotari S, Tudorache I, Haverich A, Hilfiker A. Decellularization combined with enzymatic removal of N-linked glycans and residual DNA reduces inflammatory response and improves performance of porcine xenogeneic pulmonary heart valves in an ovine in vivo model. Xenotransplantation 2019, e12571.
- Reydon TAC. Taxa hold little information about organisms: Some inferential problems in biological systematics. History and Philosophy of the Life Sciences 41: 40
- Reydon TAC. Kunz W. Species as natural entities, instrumental units and ranked taxa: New perspectives on the grouping and ranking problems. Biological Journal of the Linnean Society 126: 623-636
- Reydon TAC. Are species good units for biodiversity studies and conservation efforts? in: Casetta E., Marquez da Silva, J. & Vecchi, D. (Hrsg.): From Assessing to Conserving Biodiversity: Beyond the Species Approach, Cham: Springer, S. 167-193
- Sake HJ, Frenzel A, Lucas-Hahn A, Nowak-Imialek M, Hassel P, Hadeler KG, Hermann D, Becker R, Eylers H, Hein R, Baars W, Brinkmann A, Schwinzer R, Niemann H, Petersen B. Possible detrimental effects of beta-2-microglobulin knockout in pigs. Xenotransplantation. May 22:e12525. doi: 10.1111/xen.12525. Epub May 22
- Sarikouch S, Theodoridis K, Hilfiker A, Boethig D, Laufer G, Andreas M, Cebotari S, Tudorache I, Bobylev D, Neubert L, Teiken K, Robertus JL, Jonigk D, Beerbaum P, Haverich A, Horke A. Early Insight Into In Vivo Recellularization of Cell-Free Allogenic Heart Valves. Ann Thorac Surg. Aug;108(2):581-589. doi: 10.1016/j.athoracsur.2019.02.058. Epub Mar 28.
- Vásquez-Rivera A, Oldenhof H, Hilfiker A, Wolkers WF. Spectral fingerprinting of decellularized heart valve scaffolds. Spectrochim Acta A Mol Biomol Spectrosc. May 5;214:95-102. doi: 10.1016/j.saa.2019.02.006. Epub Feb 5.
- Wang, X., Sterr, M., Ansarullah, Burtscher, I., Böttcher, A., Beckenbauer, J., Siehler, J., Meitinger, T., Haring, H.U., Staiger, H., Cernilogar, F.M., Schotta, G., Irmler, M., Beckers, J., Wright, C.V.E., Bakhti, M., and Lickert, H. Point mutations in the PDX1 transactivation domain impair human beta-cell development and function. Mol Metab. 2019 Mar 20. pii: S2212-8778(19)30134-6. doi: 10.1016/j.molmet.2019.03.006.