2010

• Aigner B, Renner S, Kessler B, Klymiuk N, Kurome M, Wünsch A, Wolf E. Transgenic pigs as models for translational biomedical research. J Mol Med. Jul;88(7):653-64.
  
  
• Bär A, Dorfman SE, Fischer P, Hilfiker-Kleiner D, Cebotari S, Tudorache I, Suprunov M, Haverich A, Hilfiker A. The pro-angiogenic factor CCN1 enhances the re-endothelialization of biological vascularized matrices in vitro. Cardiovasc Res. Mar 1;85(4):806-13.
  
  
• Bauer A, Postrach J, Thormann M, Blanck S, Faber C, Wintersperger B, Michel S, Abicht JM, Christ F, Schmitz C, Schmoeckel M, Reichart B, Brenner P. First experience with heterotopic thoracic pig-to-baboon cardiac xenotransplantation. Xenotransplantation. May-Jun;17(3):243-9.
  
  
• Beiras-Fernandez A, Kreth S, Weis F, Ledderose C, Pottinger T, Dieguez C, Beiras A, Reichart B. Altered myocardial expression of ghrelin and its receptor (GHSR-1a) in patients with severe heart failure. Peptides; 31(12): 2222-8.
  
  
• Beiras-Fernandez A, Sadoni S, Michel S, Kur F, Vogt F, Mau H, Reichart B, Vicol C. Off-pump coronary artery bypass in a patient with congenital absence of the left pericardium and an extremely left-rotated heart. The heart surgery forum; 13(1): E63-5.
  
  
• Bigdeli AK, Beiras-Fernandez A, Kaczmarek I, Kowalski C, Schmoeckel M, Reichart B. Successful management of late right ventricular perforation after pacemaker implantation. Vascular health and risk management; 6: 27-30.
  
  
• Bigdeli AK, Kilian E, Beiras-Fernandez A, Vogt F, Reichart B Kur F. Intraoperative angiography after coronary bypass grafting in a patient presenting with a single coronary artery: a case report. The heart surgery forum; 13(3): E200-1.
  
  
• Bigdeli AK, Schmitz C, Kaczmarek I, Schmauss D, Wintersperger B, Reichart B, Sodian R. Combined aortic valve replacement and extra-anatomic aorta ascending-descending bypass for recurrent aortic coarctation. The Annals of thoracic surgery; 89(4): e22-4.
  
  
• Brenner P, Keller M, Beiras-Fernandez A, Uchita S, Kur F, Thein E, Huber H, Wimmer C, Hammer C, Schmoeckel M, Reichart B. Prevention of Hyperacute Xenograft Rejection through direct Thrombin inhibition with Hirudin. Ann Transplant:15(4):30-37.
  
  
• Denner J; Detection of a gammaretrovirus, XMRV, in the human population: Open questions and implications for xenotransplantation. Retrovirology 7:16
  
  
• Deutsch MA, Kauke T, Sadoni S, Kofler S, Schmauss D, Bigdeli AK, Weiss M, Reichart B, Kaczmarek I. Luminex-based virtual crossmatching facilitates combined third-time cardiac and de novo renal transplantation in a sensitized patient with sustained antibody-mediated cardiac allograft rejection. Pediatric transplantation; 14(8): E96-E100.
  
  
• Deutsch MA, Thieme SF, Hinterseer M, Johnson TR, Pfosser A, Reichart B, Nikolaou K, Behr J. Adult presentation of combined unilateral atresia of the right proximal pulmonary artery and left patent ductus arteriosus: case report and embryological considerations. International journal of cardiology; 141(1): e4-7.
  
  
• Dupuis J et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. Feb;42(2):105-16.
  
  
• Ehehalt F, Knoch KP, Erdmann K, Krautz C, Jäger M, Steffen A, Wegbrod C, Meisterfeld R, Kersting S, Bergert H, Kuhlisch E, Bornstein SR, Bonifacio E, Saeger HD, Solimena M. Impaired insulin turnover in islets from type 2 diabetic patients Islets; Jan.
  
  
• Eifert S, Kilian E, Beiras-Fernandez A, Juchem G, Reichart B, Lamm P. Early and mid term mortality after coronary artery bypass grafting in women depends on the surgical protocol: retrospective analysis of 3441 on- and off-pump coronary artery bypass grafting procedures. Journal of cardiothoracic surgery; 5: 90.
  
  
• Eifert S, Mair H, Boulesteix AL, Kilian E, Adamczak M, Reichart B Lamm P. Mid-term outcomes of patients with PCI prior to CABG in comparison to patients with primary CABG. Vascular health and risk management; 6: 495-501.
  
  
• Figueiredo, C., Goudeva, L., Horn, P.A., Eiz-Vesper, B., Blasczyk, R., and Seltsam, A. Generation of HLA-deficient platelets from hematopoietic progenitor cells. Transfusion 50, 1690-1701.
  
  
• Gutmann B, Obermayer D, Reichart B, Prekodravac B, Irfan M, Kremsner JM, Kappe CO. Sintered silicon carbide: a new ceramic vessel material for microwave chemistry in single-mode reactors. Chemistry; 16(40): 12182-94.
  
  
• Hartmann I, Hollweck T, Haffner S, Krebs M, Meiser B, Reichart B, Eissner G. Umbilical cord tissue-derived mesenchymal stem cells grow best under GMP-compliant culture conditions and maintain their phenotypic and functional properties. Journal of immunological methods; 363(1): 80-9.
  
  
• Hollweck T, Marschmann M, Hartmann I, Akra B, Meiser B, Reichart B, Eblenkamp M, Wintermantel E, Eissner G. Comparative analysis of adherence, viability, proliferation and morphology of umbilical cord tissue-derived mesenchymal stem cells seeded on different  titanium-coated expanded polytetrafluoroethylene scaffolds. Biomedical materials; 5(6): 065004.
  
  
• Januszewska K, Malec E, Birnbaum J, Loeff M, Sodian R, Schmitz C, Netz H, Reichart B. Paediatric heart transplantation - the impact of a ventricular assist device on operative outcomes. Kardiologia polska; 68(6): 664-9.
  
  
• Karlas A, Irgang M, Votteler J, Specke V, Özel M, Kurth R, Denner J; Characterisation of a human cell-adapted porcine endogenous retrovirus PERV-A/C. Ann. Transplantation 15(2), 45-54
  
  
• Keller M, Beiras-Fernandez A, Schmoeckel M, Reichart B, Brenner P. Influence of hypothermia and cardioplegic solutions upon the expression of the α-Gal epitope on porcine aortic endothelial cells. Exp Clin Transplant.;8(3):250-257.
  
  
• Kern, M., Popov, A., Scholz, K., Schumak, B., Djandji, D., Limmer, A., Eggle, D., Sacher, T., Zawatzky, R., Holtappels, R., et al. Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity. Gastroenterology 138, 336-346.
  Thomson, A.W., Knolle, P.A. Antigen-presenting cell function in the tolerogenic liver environment. Nature reviews immunology 10, 753-766.
  
  
• Kilian E, Fries F, Kowert A, Vogt F, Kreuzer E, Reichart B. Homograft implantation for aortic valve replacement since 15 years: results and follow-up. The heart surgery forum; 13(4): E238-42.
  
  
• Kilian EG, Sadoni S, Vicol C, Kelly R, van Hulst K, Schwaiger M, Kupatt C, Boekstegers P, Pillai R, Channon K, Hetzer R, Reichart B. Myocardial transfection of hypoxia inducible factor-1alpha via an adenoviral vector during coronary artery bypass grafting. - A multicenter phase I and safety study. Circulation journal: official journal of the Japanese Circulation Society; 74(5): 916-24.
  
  
• Klymiuk N, Wuensch A, Wolf E. Zielgerichtete Mutationen zur Erzeugung von Großtiermodellen; Biospektrum. 2010 September (17), 541-544.
  
  
• Klymiuk N, Keßler B, Kurome M, Wuensch A, Wolf E. Transgenic strategies to overcome cell-mediated and acute vascular rejection of pig-to-human xenografts. Xenotransplantation. Mar;17(2):106-107.
  
  
• Knauf Y, Wehrend A. Ovarian Cysts in the bitch. Tierärztliche Praxis 38 (K): 333-340.
  
  
• Kourtzelis I*, Markiewski MM*, Doumas M, Rafail S, Kambas K, Mitroulis I, Panagoutsos S, Passadakis P, Vargemezis V, Magotti P, Qu H, Mollnes TE, Ritis K, Lambris JD. Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis.  Blood 116(4):631-9. [*Equal contribution].
  
  
• Kues WA, Nowak-Imialek M, Haridoss S, Niemann H. Strategies for the derivation of pluripotent cells from farm animals. Reprod Domest Anim. Sep;45 Suppl 3:25-31. doi: 10.1111/j.1439-0531.2010.01663.x.

• Kuetemeyer K, Lucas-Hahn A, Petersen B, Lemme E, Hassel P, Niemann H, Heisterkamp A. Combined multiphoton imaging and automated functional enucleation of porcine oocytes using femtosecond laser pulses. J Biomed Opt;15(4):046006. doi: 10.1117/1.3463012.
  
  
• Kupatt C*, Hinkel R*, Pfosser A, El-Aouni C, Wuchrer A, Fritz A, Globisch F, Thormann M, Horstkotte J, Lebherz C, Thein E, Banfi A, Boekstegers P. Cotransfection of vascular endothelial growth factor-A and platelet-derived growth factor-B via recombinant adeno-associated virus resolves chronic ischemic malperfusion role of vessel maturation. J Am Coll Cardiol. Jul 27; 56(5):414-22.
  
  
• Lang N, Kozlik-Feldmann R, Dalla Pozza R, Hinterseer M, Sodian R, Abicht J, Kowalski C, Netz H, Reichart B, Schmitz C. Hybrid occlusion of a paravalvular leak with an Amplatzer Septal Occluder after mechanical aortic and mitral valve replacement. The Journal of thoracic and cardiovascular surgery; 139(1): 221-2.
  
  
• Lang N, Kozlik-Feldmann R, Meyer-Gold A, Fuchs F, Lehner A, Abicht J, Sodian R, Vasilyev N, del Nido P, Netz H, Reichart B, Schmitz C. Modification of a hybrid technique for closure of muscular ventricular septal defects in a pig model. The heart surgery forum; 13(5): E299-304.
  
  
• Langhammer S, Fiebig U, Hübner J, Kurth R, Denner J; Increased neutralizing antibody response after simultaneous immunization with Leucogen and the feline leukemia virus transmembrane protein. Intervirology 54, 78-86
  
  
• Li S, Flisikowska T, Kessler B, Gungor T, Kind A, Wolf E, Schnieke A, Zakhartchenko V. Cloning rabbits from non-transfected and GFP-transfected mesenchymal stem cells. Reproduction in Domestic Animals, 45: 29-30.
  
  
• Li S, Flisikowska T, Kessler B, Gungor T, Kind A, Wolf E, Schnieke A, Zakhartchenko V. Production of cloned transgenic rabbits from mesenchymal stem cells. Reproduction Fertility and Development, 22: 192.
  
  
• Ludwig B, Zimerman B, Steffen A, Yavriants K, Azarov D, Reichel A, Vardi P, German T, Shabtay N, Rotem A, Evron Y, Neufeld T, Mimon S, Ludwig S, Brendel MD, Bornstein SR, Barkai U. A Novel Device for Islet Transplantation Providing Immune Protection and Oxygen Supply. Horm Metab Res. Dec;42(13):918-22.
  
  
• Ludwig B,Ludwig S, Steffen A, Saeger HD, Bornstein SR. Islet versus pancreas transplantation in type 1 diabetes: competitive or complementary? Current Diabetes Reports; 10(6):506-11. Dec
  
  
• Ludwig B, Ziegler CG, Schally AV, Richter C, Steffen A, Jabs N, Funk RH, Brendel M, Block N, Ehrhart-Bornstein M, Bornstein SR. Agonist of growth hormone-releasing hormone as a potential effector for survival and proliferation of pancreatic islets. Proceedings of the National Academy of Sciences; 107(28):12623-12628. Jul
  
  
• Ludwig B,  Ludwig S, Brendel M, Steffen A, Witzigmann H, Solimena M, Bonifacio E, Palm C, Passauer J, Leike S, Kersting S, Saeger HD.  Insel- und Pankreas/Nieren-Transplantation am Universitätsklinikum Dresden Diabetologie Und Stoffwechsel - DIABETOL STOFFWECHS; 5. Jan
  
  
• Liu Y, Suckale J, Masjkur J, Magro MG, Steffen A, Anastassiadis K, Solimena M. Tamoxifen-independent recombination in the RIP-CreER mouse.; PLoS ONE; 5(10):e13533. Jan
  
  
• Mauth C, Pavlica S, Deiwick A, Steffen A, Bader A. The influence of oxygen supply on metabolism of neural cells cultured on a gas-permeable PTFE foil. Biotechnology Progress; 26(6):1724-32. Jan
  
  
• Mitroulis I*, Kourtzelis I*, Kambas K, Rafail S, Chrysanthopoulou A, Speletas M, Ritis K. Regulation of the autophagic machinery in human neutrophils. Eur J Immunol 40(5):1461-72 [*Equal contribution]. Among the most cited research articles published in the journal during 2010.
  
  
• Niemann, H., Carnwath, J.W., Herrmann, D., Wieczorek, G., Lemme, E., Lucas-Hahn, A., Olek, S. DNA methylation patterns reflect epigenetic reprogramming in bovine em
  
  
• Nowak-Imialek M, Kues WA, Rudolph C, Schlegelberger B, Taylor U, Carnwath JW, Niemann H. Preferential loss of porcine chromosomes in reprogrammed interspecies cell hybrids. Cell Reprogram. Feb;12(1):55-65. doi: 10.1089/cell.2009.0045.

• Pabinger I, Tiede A, Kalina U, Knaub S, Germann R, Ostermann H. Impact of infusion speed on the safety and effectiveness of prothrombin complex concentrate: a prospective clinical trial of emergency anticoagulation reversal. Ann Hematol., 89: 309-16
  
  
• Pfosser O; El-Aouni C; Pfisterer  I; Dietz M; Globisch F; Stachel G; Trenkwalder T; Pinkenburg O; Hinkel R; Sperandio M; Hatzopoulos AK; Boekstegers P; Bals R; Kupatt C. NF kB activation in embryonic endothelial progenitor cells enhances neovascularization via PSGL-1 mediated recruitment: Novel role for LL37, Stem Cells; 28:376-85
  
  
• Plege A. Borns K, Baars W, Klempnauer J, Schwinzer R. Downregulation of cytolytic activity of human effector cells by transgenic expression of human PD-Ligand-1 on porcine target cells. Transplant Int 23:1293-300
  
  
• Plog S, Mundhenk L, Bothe M K, Klymiuk N, Gruber A D. Tissue and Cellular Expression Patterns of Porcine CFTR: Similarities and Differences to Human CFTR. J Histochem Cytochem. May 24.
  
  
• Poschner BC, Fischer K, Herrmann JR, Hofmann MW, Langosch D. Structural features of fusogenic model transmembrane domains that differentially regulate inner and outer leaflet mixing in membrane fusion. Mol Membr Biol. 2010;27(1):1-10.
  
  
• Renner S, Fehlings C, Herbach N, Hofmann A, von Waldthausen DC, Kessler B, Ulrichs K, Chodnevskaja I, Moskalenko V, Amselgruber W, Göke B, Pfeifer A, Wanke R, Wolf E, Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function. Diabetes 2010 May;59(5):1228-38. Epub Feb 25. PubMed PMID: 20185813.
  
  
• Reydon, T.A.C. (2010): ‘Natural kind theory as a tool for philosophers of science’, in: Suárez, M., Dorato, M. & Rédei, M. (Eds): EPSA – Epistemology and Methodology of Science: Launch of the European Philosophy of Science Association, Dordrecht: Springer, pp. 245-254.
  
  
• Saxena R. et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge Nat Genet. Feb;42(2):142-8.
  
  
• Schmitz C, Sodian R, Malec E, Januszewska K, Kaczmarek I, Kofler S, Bruegger C, Kowalski C, Lang N, Reichart B. Successful implantation of a Berlin Heart ventricular assist device in ventricular heart failure 23 years after Senning operation. The Journal of thoracic and cardiovascular surgery; 139(3): e30-1.
  
  
• Seiler S, Reichart B, Roth D, Seibert E, Fliser D, Heine GH. FGF-23 and future cardiovascular events in patients with chronic kidney disease before initiation of dialysis treatment. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association; 25(12): 3983-9.
  
  
• Sodian R, Schaefermeier P, Abegg-Zips S, Kuebler WM, Shakibaei M, Daebritz S, Ziegelmueller J, Schmitz C, Reichart B. Use of human umbilical cord blood-derived progenitor cells for tissue-engineered heart valves. The Annals of thoracic surgery; 89(3): 819-28.
  
  
• Solimena M and Speier S. Insulin release: shedding light on a complex matter. Cell Metabolism 12, 5-6.
  
  
• Stengel S, Fiebig U, Kurth R, Denner J; Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation. Genes, Chromosomes and Cancer 49(5):401-11
  
  
• Tiede A, Eisert R, Czwalinna A, Miesbach W, Scharrer I, Ganser A. Acquired haemophilia caused by non-haemophilic factor VIII gene variants. Ann Hematol. 2010, 89: 607-612.
  
  
• van Bürck L, Blutke A, Kaut S, Rathkolb B, Klaften M, Wagner S, Kemter E, Hrabé de Angelis M, Wolf E, Aigner B, Wanke R, Herbach N. Phenotypic and phatomorphological characteristics of a novel mutant mouse model for Maturiy onset diabetes of the young type 2 (MODY 2). Am J Physiol Endocinol Metab 298: 512 - 523
  
  
• Vondran, FWR, Timrott K, Tross J, Kollrich S, Schwarz A, Lehner F, Klempnauer J, Becker T, Schwinzer R. Impact of Basiliximab on regulatory T-cells early after kidney transplantation: down-regulation of CD25 by receptor modulation. Transplant Int, 23:514-23.
  
  
• Walther S, Beiras-Fernandez A, Csapo C, Munzing S, Stief CG, Hammer C, Reichart B, Thein E. Influence of polyclonal antithymocyte globulins on the expression of adhesion molecules of isolated human umbilical vein endothelial cells. Transplantation proceedings; 42(5): 1931-4.
  
  
• Weis F, Beiras-Fernandez A, Sodian R, Kaczmarek I, Reichart B, Beiras A, Schelling G, Kreth S. Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. Journal of molecular and cellular cardiology; 48(6): 1187-93.
  
  
• Wickström, S.A., Lange, A., Hess, M.W., Polleux, J., Spatz, J.P., Kruger, M., Pfaller, K., Lambacher, A., Bloch, W., Mann, M. Huber, L.A., and Fässler, R. Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae. Dev Cell 19, 574-588.
  
  
• Wickström, S.A., Lange, A., Montanez, E., and Fässler, R. The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! EMBO J 29, 281-291.
  
  
• Wilk E., Marquardt N., Pokoyski C., Schmidt R.E., Jacobs R. Murine CXCR3+CD27bright NK cells resemble the human CD56bright NK cell population. Eur J Immunol. 2010 May:40(5):1428-39.
  
  
• Wolf E, Renner S, Kessler B, Kurome M, Wuensch A, Klymiuk N, Aigner B. Large animal Models for Translational Science in Medicine. Nova Acta Leoplodina NF 98, Nr. 361, 65-86
  
  
• Ziegelmueller JA, Zaenkert EK, Schams R, Lackermair S, Schmitz C, Reichart B, Sodian R. Optical monitoring during bioreactor conditioning of tissue-engineered heart valves. ASAIO journal; 56(3): 228-31.
  
  
• Zitta K, Brandt B,  Wuensch A, Meybohm A, Bein B, Steinfath M,  Scholz J, Albrecht M. Interleukin-1β regulates cell proliferation and activity of extracellular matrix remodelling enzymes in cultured primary pig heart cells. Biochemical and Biophysical Research Communications. Sept 399(4): 542-47