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RESEARCH AREAS
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A: Immunity/Tolerance
- A1: Targeting stimulatory and inhibitory receptor/ligand interactions to diminish human anti-pig immune responses
- A2: Immunomodulation by viral vectors
- A3: Targeting the Islet / Vascular Inflammation Interface in xenograft dysfunction
- A4: Regulatory T cells in Xenotransplantation
- A5: Modulating early and late immune rejection of xenogenic islet grafts in optimized humanized mice – from preclinical tools to clinical application.
- B: Novel transgenic strategies
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C: Preclinical and clinical xenotransplantation
- C1: Suitability of porcine islets and novel cell sources for diabetes transplantation therapy
- C3: Treatment of type 1 diabetes with porcine islet cells: transplantation of multi-transgenic islets expressing immunomodulatory molecules
- C4: Porcine islet macroencapsulation – a concept for xenogeneic islet transplantation
- C7: Preclinical assessment of antigen-reduced decellularized porcine heart valves
- C8: Strategies in preclinical cardiac xenotransplantation
- Z: Central Projects
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