Startseite » Publications » Articles

2019

  1. Bongiovanni D, Santamaria G, Klug M, Santovito D, Felicetta A, Hristov M, von Scheidt M, Aslani M, Cibella J, Weber C, Moretti A, Laugwitz KL, Peano C, Bernlochner I. Transcriptome Analysis of Reticulated Platelets Reveals a Prothrombotic Profile. Thrombosis and haemostasis. 2019. Pubmed

  2. Van Avondt K, Nur E, Zeerleder S. Mechanisms of haemolysis-induced kidney injury. Nat Rev Nephrol. 2019. Pubmed

  3. Mauler M, Hilgendorf I, Duerschmied D. Response by Mauler et al to Letter Regarding Article, "Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation". Circulation. 2019;140:e292-e293. Pubmed

  4. Cimen I, Yildirim Z, Dogan AE, Yildirim AD, Tufanli O, Onat UI, Nguyen U, Watkins SM, Weber C, Erbay E. Double bond configuration of palmitoleate is critical for atheroprotection. Mol Metab. 2019. Pubmed

  5. Nagy M, van Geffen JP, Stegner D, Adams DJ, Braun A, de Witt SM, Elvers M, Geer MJ, Kuijpers MJE, Kunzelmann K, Mori J, Oury C, Pircher J, Pleines I, Poole AW, Senis YA, Verdoold R, Weber C, Nieswandt B, Heemskerk JWM, Baaten C. Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis. Front Cardiovasc Med. 2019;6:99. Pubmed

  6. Santovito D, Marcantonio P, Mastroiacovo D, Natarelli L, Mandolini C, De Nardis V, Paganelli C, De Cesare D, Affaitati G, Giamberardino MA, Stellin L, Pinelli M, Weber C, De Blasis G, Occhiuzzi U, Bucci M, Desideri G, Cipollone F. High dose rosuvastatin increases ABCA1 transporter in human atherosclerotic plaques in a cholesterol-independent fashion. Int J Cardiol. 2019. Pubmed

  7. Varasteh Z, Mohanta S, Robu S, Braeuer M, Li Y, Omidvari N, Topping G, Sun T, Nekolla SG, Richter A, Weber C, Habenicht A, Haberkorn UA, Weber WA. Molecular imaging of fibroblast activity after myocardial infarction using a (68)Ga-labelled fibroblast activation protein inhibitor FAPI-04. J Nucl Med. 2019. Pubmed

  8. de Juan A, Ince LM, Pick R, Chen CS, Molica F, Zuchtriegel G, Wang C, Zhang D, Druzd D, Hessenauer MET, Pelli G, Kolbe I, Oster H, Prophete C, Hergenhan SM, Albrecht U, Ripperger J, Montanez E, Reichel CA, Soehnlein O, Kwak BR, Frenette PS, Scheiermann C. Artery-Associated Sympathetic Innervation Drives Rhythmic Vascular Inflammation of Arteries and Veins. Circulation. 2019. Pubmed

  9. Natarelli L, Weber C. Next-Generation Therapeutic Concepts for Atherosclerosis: Focus on Cell Specificity and Noncoding RNAs. Thromb Haemost. 2019;119:1199-1201. Pubmed

  10. Joppich M, Weber C, Zimmer R. Using Context-Sensitive Text Mining to Identify miRNAs in Different Stages of Atherosclerosis. Thromb Haemost. 2019;119:1247-1264. Pubmed
  11. Leiria LO, Wang CH, Lynes MD, Yang K, Shamsi F, Sato M, Sugimoto S, Chen EY, Bussberg V, Narain NR, Sansbury BE, Darcy J, Huang TL, Kodani SD, Sakaguchi M, Rocha AL, Schulz TJ, Bartelt A, Hotamisligil GS, Hirshman MF, van Leyen K, Goodyear LJ, Bluher M, Cypess AM, Kiebish MA, Spite M, Tseng YH. 12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat. Cell Metab. 2019. Pubmed

  12. Hu D, Yin C, Luo S, Habenicht AJR, Mohanta SK. Vascular Smooth Muscle Cells Contribute to Atherosclerosis Immunity. Front Immunol. 2019;10:1101. Pubmed
  13. Koenen RR. Lysophosphatidylcholine in Platelet Microvesicles: The Grease for Cardiovascular Disease. Thromb Haemost. 2019. Pubmed

  14. Beldman TJ, Malinova TS, Desclos E, Grootemaat AE, Misiak ALS, van der Velden S, van Roomen C, Beckers L, van Veen HA, Krawczyk PM, Hoebe RA, Sluimer JC, Neele AE, de Winther MPJ, van der Wel NN, Lutgens E, Mulder WJM, Huveneers S, Kluza E. Nanoparticle-Aided Characterization of Arterial Endothelial Architecture During Atherosclerosis Progression and Metabolic Therapy. ACS Nano. 2019. Pubmed
  15. Eckardt V, Weber C, von Hundelshausen P. Glycans and Glycan-Binding Proteins in Atherosclerosis. Thromb Haemost. 2019. Pubmed

  16. Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, Siuda D, Soehnlein O, Wittig I, Heidler J, Weigert A, Fleming I. Myeloid-Specific Deletion of the AMPKalpha2 Subunit Alters Monocyte Protein Expression and Atherogenesis. Int J Mol Sci. 2019;20.Pubmed
  17. Rasmuson J, Kenne E, Wahlgren M, Soehnlein O, Lindbom L. Heparinoid sevuparin inhibits Streptococcus-induced vascular leak through neutralizing neutrophil-derived proteins. FASEB J. 2019:fj201900627R. Pubmed
  18. Denisov SS, Ippel JH, Heinzmann ACA, Koenen RR, Ortega-Gomez A, Soehnlein O, Hackeng TM, Dijkgraaf I. Tick saliva protein Evasin-3 modulates chemotaxis by disrupting CXCL8 interactions with glycosaminoglycans and CXCR2. J Biol Chem. 2019. Pubmed
  19. Bianchini M, Duchene J, Santovito D, Schloss MJ, Evrard M, Winkels H, Aslani M, Mohanta SK, Horckmans M, Blanchet X, Lacy M, von Hundelshausen P, Atzler D, Habenicht A, Gerdes N, Pelisek J, Ng LG, Steffens S, Weber C, Megens RTA. PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function. Sci Immunol. 2019;4. Pubmed

  20. Ketelhuth DFJ, Lutgens E, Back M, Binder CJ, Van den Bossche J, Daniel C, Dumitriu IE, Hoefer I, Libby P, O'Neill L, Weber C, Evans P. Immunometabolism and atherosclerosis: perspectives and clinical significance- A position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology. Cardiovasc Res. 2019. Pubmed

  21. Bekkering S, Stiekema LCA, Bernelot Moens S, Verweij SL, Novakovic B, Prange K, Versloot M, Roeters van Lennep JE, Stunnenberg H, de Winther M, Stroes ESG, Joosten LAB, Netea MG, Riksen NP. Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia. Cell Metab. 2019. Pubmed

  22. de Winther MPJ, Glass CK. Leducq Epigenetics of Atherosclerosis Network. Circ Res. 2019;124:1697-1700. Pubmed

  23. Dekkers KF, Neele AE, Jukema JW, Heijmans BT, de Winther MPJ. Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites. Epigenetics Chromatin. 2019;12:34. Pubmed

  24. Ferraro B, Leoni G, Hinkel R, Ormanns S, Paulin N, Ortega-Gomez A, Viola JR, de Jong R, Bongiovanni D, Bozoglu T, Maas SL, D'Amico M, Kessler T, Zeller T, Hristov M, Reutelingsperger C, Sager HB, Doring Y, Nahrendorf M, Kupatt C, Soehnlein O. Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair. J Am Coll Cardiol. 2019;73:2990-3002. Pubmed
  25. van der Vorst EPC, Peters LJF, Muller M, Gencer S, Yan Y, Weber C, Doring Y. G-Protein Coupled Receptor Targeting on Myeloid Cells in Atherosclerosis. Front Pharmacol. 2019;10:531. Pubmed
  26. Welz PS, Zinna VM, Symeonidi A, Koronowski KB, Kinouchi K, Smith JG, Guillen IM, Castellanos A, Crainiciuc G, Prats N, Caballero JM, Hidalgo A, Sassone-Corsi P, Benitah SA. BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis. Cell. 2019;177:1436-1447 e1412. Pubmed
  27. Hidalgo A, Chilvers ER, Summers C, Koenderman L. The Neutrophil Life Cycle. Trends Immunol. 2019. Pubmed
  28. Soehnlein O. Neutrophil Research, Quo Vadis? Trends Immunol. 2019. Pubmed

  29. Cassatella MA, Ostberg NK, Tamassia N, Soehnlein O. Biological Roles of Neutrophil-Derived Granule Proteins and Cytokines. Trends Immunol. 2019. Pubmed
  30. Wichapong K, Poelman H, Ercig B, Hrdinova J, Liu X, Lutgens E, Nicolaes GA. Rational modulator design by exploitation of protein-protein complex structures. Future Med Chem. 2019. Pubmed

  31. Sager HB, Husser O, Steffens S, Laugwitz KL, Schunkert H, Kastrati A, Ndrepepa G, Kessler T. Time-of-day at symptom onset was not associated with infarct size and long-term prognosis in patients with ST-segment elevation myocardial infarction. J Transl Med. 2019;17:180. Pubmed
  32. Silvestre-Roig C, Fridlender ZG, Glogauer M, Scapini P. Neutrophil Diversity in Health and Disease. Trends Immunol. 2019. Pubmed
  33. Lutgens E, Atzler D, Doring Y, Duchene J, Steffens S, Weber C. Immunotherapy for cardiovascular disease. Eur Heart J. 2019. Pubmed

  34. Vila-Caballer M, Gonzalez-Granado JM, Zorita V, Abu Nabah YN, Silvestre-Roig C, Del Monte-Monge A, Molina-Sanchez P, Ait-Oufella H, Andres-Manzano MJ, Sanz MJ, Weber C, Kremer L, Gutierrez J, Mallat Z, Andres V. Disruption of the CCL1-CCR8 axis inhibits vascular Treg recruitment and function and promotes atherosclerosis in mice. J Mol Cell Cardiol. 2019. Pubmed

  35. Busygina K, Denzinger V, Bernlochner I, Weber C, Lorenz R, Siess W. Btk Inhibitors as First Oral Atherothrombosis-Selective Antiplatelet Drugs? Thromb Haemost. 2019 May;Epub. Pubmed
  36. de Winther MPJ, Lutgens E. The Link between Hematopoiesis and Atherosclerosis. N Engl J Med. 2019;380:1869-1871. Pubmed
  37. Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gomez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, Gonzalez-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O. Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature. 2019 May; Epub. Pubmed

  38. Paloschi V, Winter H, Viola J, Soehnlein O, Maegdefessel L. Mechanistic Links between Non-Coding RNAs and Myeloid Cell Inflammation in Atherosclerosis. Thromb Haemost. 2019 Apr; Epub. Pubmed
  39. Neidhart M, Pajak A, Laskari K, Riksen NP, Joosten LAB, Netea MG, Lutgens E, Stroes ESG, Ciurea A, Distler O, Grigorian M, Karouzakis E. Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides. Front Immunol. 2019;10:791. Pubmed
  40. Bollenbach A, Cordts K, Hanff E, Atzler D, Choe CU, Schwedhelm E, Tsikas D. Evidence by GC-MS that lysine is an arginase-catalyzed metabolite of homoarginine in vitro and in vivo in humans. Anal Biochem. 2019 Apr; Epub. Pubmed
  41. van der Vorst EPC, Donners M. ADAM8 in the cardiovascular system: An innocent bystander with clinical use? Atherosclerosis. 2019 Apr; Epub. Pubmed
  42. Ciato D, Li R, Monteserin Garcia JL, Papst L, D'Annunzio S, Hristov M, Tichomirowa MA, Belaya Z, Rozhinskaya L, Buchfelder M, Theodoropoulou M, Paez-Pereda M, Stalla GK. Inhibition of HSF1 enhances repressive molecular mechanisms on POMC promoter. Neuroendocrinology. 2019 Apr; Epub. Pubmed

  43. Puhl SL, Steffens S. Neutrophils in Post-myocardial Infarction Inflammation: Damage vs. Resolution? Front Cardiovasc Med. 2019;6:25. Pubmed

  44. Puhl SL. Cannabinoid-sensitive receptors in cardiac physiology and ischaemia. Biochim Biophys Acta Mol Cell Res. 2019 Mar; Epub. Pubmed
  45. Cossio I, Lucas D, Hidalgo A. Neutrophils as regulators of the hematopoietic niche. Blood. 2019 Mar; Epub. Pubmed
  46. Worthmann A, Schlein C, Berbee JFP, Rensen PCN, Heeren J, Bartelt A. Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression. Nutrients. 2019;11. Pubmed
  47. Centa M, Jin H, Hofste L, Hellberg S, Busch A, Baumgartner R, Verzaal NJ, Lind Enoksson S, Perisic Matic L, Boddul SV, Atzler D, Li DY, Sun C, Hansson GK, Ketelhuth DFJ, Hedin U, Wermeling F, Lutgens E, Binder CJ, Maegdefessel L, Malin SG. Germinal Center-Derived Antibodies Promote Atherosclerosis Plaque Size and Stability. Circulation. 2019 Mar; Epub. Pubmed
  48. Steffens S, Weber C. Immunotherapy for Atherosclerosis-Novel Concepts. Thromb Haemost. 2019;119:515-516. Pubmed
  49. Thiem K, Hoeke G, van den Berg S, Hijmans A, Jacobs CWM, Zhou E, Mol IM, Mouktaroudi M, Bussink J, Kanneganti TD, Lutgens E, Stienstra R, Tack CJ, Netea MG, Rensen PCN, Berbee JFP, van Diepen JA. Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice. Sci Rep. 2019;9:4337. Pubmed

  50. Ng LG, Ostuni R, Hidalgo A. Heterogeneity of neutrophils. Nat Rev Immunol. 2019. Pubmed

  51. Onat UI, Yildirim AD, Tufanli Ö, Çimen I, Kocatürk B, Veli Z, Hamid SM, Shimada K, Chen S, Sin J, Shah PK, Gottlieb RA, Arditi M, Erbay E. Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis. Journal of the American College of Cardiology. 2019;73:1149-1169. doi

  52. Doring Y, van der Vorst EPC, Duchene J, Jansen Y, Gencer S, Bidzhekov K, Atzler D, Santovito D, Rader DJ, Saleheen D, Weber C. CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease. Circulation. 2019;139:1338-1340. Pubmed
  53. van der Vorst EPC, Mandl M, Muller M, Neideck C, Jansen Y, Hristov M, Gencer S, Peters LJF, Meiler S, Feld M, Geiselhoringer AL, de Jong RJ, Ohnmacht C, Noels H, Soehnlein O, Drechsler M, Weber C, Doring Y. Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions. Arterioscler Thromb Vasc Biol. 2019 Feb; Epub. Pubmed

  54. Guillamat-Prats R, Rami M, Herzig S, Steffens S. Endocannabinoid Signalling in Atherosclerosis and Related Metabolic Complications. Thromb Haemost. 2019 Feb; Epub. Pubmed

  55. Noels H, Weber C, Koenen RR. Chemokines as Therapeutic Targets in Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2019 Feb; Epub. Pubmed

  56. Van Avondt K, Maegdefessel L, Soehnlein O. Therapeutic Targeting of Neutrophil Extracellular Traps in Atherogenic Inflammation. Thromb Haemost. 2019 Feb; Epub. Pubmed

  57. Gencer S, van der Vorst EPC, Aslani M, Weber C, Doring Y, Duchene J. Atypical Chemokine Receptors in Cardiovascular Disease. Thromb Haemost. 2019 Feb; Epub. Pubmed
  58. Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossio I, Lechuga-Vieco AV, Garcia-Prieto J, Gomez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, Lopez J, Bidzhekov K, Bachelerie F, Abad-Santos F, Munoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibanez B, Hidalgo A. A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. Immunity. 2019 Jan; Epub. Pubmed
  59. Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR. High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue. Front Physiol. 2019;9:1913. Pubmed
  60. Cordts K, Grzybowski R, Lezius S, Luneburg N, Atzler D, Neu A, Hornig S, Boger RH, Gerloff C, Magnus T, Thomalla G, Schwedhelm E, Grant PJ, Choe CU. Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA2DS2-VASc score in three cross-sectional studies. J Neurol Sci. 2019;397:156-161. Pubmed
  61. Yin C, Ackermann S,  Mohanta Z Ma,  Zhang SK, Li CY, Nietzsche S, Westermann M, Peng L, Hu D, Bontha SV, Srikakulapu P, Beer M, Megens RTA, Steffens S, Hildner M, Halder LD, Eckstein HH, Pelisek J, Herms J, Roeber S, Arzberger T, Borodovsky A, Habenicht L, Binder CJ, Weber C, Zipfel PF, Skerka C, Habenicht AJR. ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nat Med. 2019 Jan; Epub. Pubmed
  62. Denzinger V, Busygina K, Jamasbi J, Pekrul I, Spannagl M, Weber C, Lorenz R, Siess W. Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib. Thromb Haemost. 2019 Jan; Epub. Pubmed
  63. van der Vorst EPC, Weber C. Novel Features of Monocytes and Macrophages in Cardiovascular Biology and Disease. Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):e30–7. Pubmed
  64. Varasteh Z, Mohanta S, Li Y, López Armbruster N, Braeuer M, Nekolla SG, Habenicht A, Sager HB, Raes G, Weber W, Hernot S, Schwaiger M. Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using (68)Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques. EJNMMI Res. 2019 Jan;9(1):5. Pubmed
  65. de Winther MPJ, Dallinga-Thie GM. Introduction to the thematic review series on different levels of genetic regulation of cardiovascular disease. Atherosclerosis. 2018 Dec; Epub. Pubmed
  66. Nitz K, Lacy M, Atzler D. Amino Acids and Their Metabolism in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2019 Jan; Epub. Pubmed
  67. Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueröder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Köckritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M. To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell Death Differ. 2019 Jan; Epub. Pubmed
  68. van Beek AA, Van den Bossche J, Mastroberardino PG, de Winther MPJ, Leenen PJM. Metabolic alterations in aging macrophages: ingredients for inflammaging? Trends Immunol. 2019 Jan; Epub. Pubmed
  69. Meeuwsen JAL, de Vries JJ, van Duijvenvoorde A, van der Velden S, van der Laan SW, van Koeverden ID, van de Weg SM, de Borst GJ, de Winther MPJ, Kuiper J, Pasterkamp G, Hoefer IE, de Jager SCA; Queen of Hearts Consortium. Circulating CD14(+)CD16(-) classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients. J Mol Cell Cardiol. 2019 Jan; Epub. Pubmed
  70. Guillamat Prats R, Rami M, Ring L, Rinne P, Lauer E, Lenglet S, Thomas A, Pagano S, Vuilleumier N, Cravatt BF, Weber C, Faussner A, Steffens S. Deficiency of monoacylglycerol lipase enhances IgM plasma levels and limits atherogenesis in a CB2-dependent manner. Thromb Haemost.  2019 Jan; Epub. Pubmed
  71. Weber C, Lip GYH. Thrombosis and Haemostasis 2018 Editor’s choice papers. Thromb Haemost.  2019 Jan;119(1):183–6. Pubmed
  72. Lip GYH, Weber C. Thrombosis and Haemostasis wishes you a happy new year ahead! Thromb Haemost. 2019 Jan;119(1):1–2. Pubmed
  73. Lacy M, Atzler D, Liu R, de Winther M, Weber C, Lutgens E. Interactions between dyslipidemia and the immune system and their relevance as putative therapeutic targets in atherosclerosis. Pharmacol Ther. 2019 Jan;193:50–62. Pubmed
  74. Tuñón J, Bäck M, Badimón L, Bochaton-Piallat ML, Cariou B, Daemen MJ, Egido J, Evans PC, Francis SE, Ketelhuth DF, Lutgens E, Matter CM, Monaco C, Steffens S, Stroes E, Vindis C, Weber C, Hoefer IE; ESC Working Group on Atherosclerosis and Vascular Biology. Identifying the anti-inflammatory response to lipid lowering therapy: a position  paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology. Cardiovasc Res. 2019 Jan;115(1):10–9. Pubmed
  75. Bosch L, de Haan J, Seijkens T, van Tiel C, Brans M, Pasterkamp G, Lutgens E, de Jager S. Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure. Int J Cardiol. 2018 Dec; Epub. Pubmed
  76. Aarts SABM, Reiche ME, den Toom M, Beckers L, Gijbels MJJ, Gerdes N, de Winther MPJ, Lutgens E. Macrophage CD40-signaling drives experimental autoimmune encephalomyelitis. J Pathol. 2019;247:471-480. Pubmed
  77. Cremer S, Michalik KM, Fischer A, Pfisterer L, Jaé N, Winter C, Boon RA, Muhly-Reinholz M, John D, Uchida S, Weber C, Poller W, Günther S, Braun T, Li DY, Maegdefessel L, Matic Perisic L, Hedin U, Soehnlein O, Zeiher A, Dimmeler S. Hematopoietic deficiency of the long non-coding RNA MALAT1 promotes atherosclerosis and plaque inflammation. Circulation. 2018 Nov; Epub. Pubmed
  78. González-Ramos S, Paz-García M, Rius C, Del Monte-Monge A, Rodríguez C, Fernández-García V, Andrés V, Martínez-González J, Lasunción MA, Martín-Sanz P, Soehnlein O, Boscá L. Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1. FASEB J. 2018 Nov; Epub. Pubmed
  79. Pfeiler S, Thakur M, Grünauer P, Megens RTA, Joshi U, Coletti R, Samara V, Müller-Stoy G, Ishikawa-Ankerhold H, Stark K, Klingl A, Fröhlich T, Arnold GJ, Wörmann S, Bruns CJ, Algül H, Weber C, Massberg S, Engelmann B. CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis. FASEB J. 2018 Sep; Epub. Pubmed
  80. Puhl SL, Weeks KL, Güran A, Ranieri A, Boknik P, Kirchhefer U, Müller F, Avkiran M. Role of type 2A phosphatase regulatory subunit B56alpha in regulating cardiac responses to beta-adrenergic stimulation in vivo. Cardiovasc Res. 2019;115:519-529. Pubmed
  81. Schloss MJ, Horckmans M, Guillamat-Prats R, Hering D, Lauer E, Lenglet S, Weber C, Thomas A, Steffens S. 2-arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction. Cardiovasc Res. 2018 Sep; Epub. Pubmed
  82. Pfeiler S, Winkels H, Kelm M, Gerdes N. IL-1 family cytokines in cardiovascular disease. Cytokine. 2017 Nov; Epub. Pubmed
  83. Seijkens TTP, Poels K, Meiler S, van Tiel CM, Kusters PJH, Reiche M, Atzler D, Winkels H, Tjwa M, Poelman H, Slütter B, Kuiper J, Gijbels M, Kuivenhoven JA, Matic LP, Paulsson-Berne G, Hedin U, Hansson GK, Nicolaes GAF, Daemen MJAP, Weber C, Gerdes N, de Winther MPJ, Lutgens E. Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death. Eur Heart J. 2019 Jan;40(4):372–82. Pubmed
  84. Bijnen M, van de Gaar J, Vroomen M, Gijbels MJ, de Winther M, Schalkwijk CG, Wouters K. Adipose tissue macrophages do not affect atherosclerosis development in mice. Atherosclerosis. 2019;281:31-37.Pubmed
  85. Brandsma E, Kloosterhuis NJ, Koster M, Dekker DC, Gijbels MJJ, van der Velden S, Rios-Morales M, van Faassen MJR, Loreti MG, de Bruin A, Fu J, Kuipers F, Bakker BM, Westerterp M, de Winther MPJ, Hofker MH, van de Sluis B, Koonen DPY. A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis. Circulation research. 2019;124:94-100. Pubmed
  86. Treviño-Villarreal JH, Reynolds JS, Bartelt A, Langston PK, MacArthur MR, Arduini A, Tosti V, Veronese N, Bertozzi B, Brace LE, Mejia P, Trocha K, Kajitani GS, Longchamp A, Harputlugil E, Gathungu R, Bird SS, Bullock AD, Figenshau RS, Andriole GL, Thompson A, Heeren J, Ozaki CK, Kristal BS, Fontana L, Mitchell JR. Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5–dependent and –independent mechanisms. JCI Insight. 2018 Nov; Epub. Pubmed

 
 
IPEKlogo

Direktor:

Prof. Dr. med. Christian Weber

Institute for Cardiovascular Prevention (IPEK)

 

Pettenkoferstraße 8a & 9

80336 München

 

Tel.: 089-4400-54351

Fax: 089-4400-54352

Mail: ipek.office@med.lmu.de