2018

  1. Aarts SABM, Reiche ME, den Toom M, Beckers L, Gijbels MJJ, Gerdes N, de Winther MPJ, Lutgens E. Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction. PLoS One. 2018;13:e0202150. Pubmed
  2. Ameti R, Melgrati S, Radice E, Cameroni E, Hub E, Thelen S, Rot A, Thelen M. Characterization of a chimeric chemokine as a specific ligand for ACKR3. J Leukoc Biol. 2018;104:391-400. Pubmed
  3. Atzler D, de Winther MPJ. DARC matter(s) for inflammatory cells. Cardiovasc Res. 2018;114:e11-e13. Pubmed
  4. Baardman J, Verberk SGS, Prange KHM, van Weeghel M, van der Velden S, Ryan DG, Wüst RCI, Neele AE, Speijer D, Denis SW, Witte ME, Houtkooper RH, O'neill LA, Knatko EV, Dinkova-Kostova AT, Lutgens E, de Winther MPJ, Van den Bossche J. A defective pentose phosphate pathway reduces inflammatory macrophage responses during hypercholesterolemia. Cell Rep. 2018;25:2044-2052.e5. Pubmed
  5. Baaten CCFMJ, Meacham S, de Witt SM, Feijge MAH, Adams DJ, Akkerman JN, Cosemans JMEM, Grassi L, Jupe S, Kostadima M, Mattheij NJA, Prins MH, Ramirez-Solis R, Soehnlein O, Swieringa F, Weber C, White JK, Ouwehand WH, Heemskerk JWM. A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding. Blood. 2018;132 (24):e35-e46. Pubmed
  6. Bahls M, Atzler D, Markus MRP, Friedrich N, Böger RH, Völzke H, Felix SB, Schwedhelm E, Dörr M. Low-Circulating Homoarginine is associated with dilatation and decreased function of the left ventricle in the general population. Biomolecules. 2018;8:e63. Pubmed
  7. Baldassarri F, Schwedhelm E, Atzler D, Böger RH, Cordts K, Haller B, Pressler A, Müller S, Suchy C, Wachter R, Düngen HD, Hasenfuss G, Pieske B, Halle M, Edelmann F, Duvinage A. Relationship between exercise intervention and NO pathway in patients with heart failure with preserved ejection fraction. Biomarkers. 2018;23:540-550. Pubmed
  8. Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Pérez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J. Inhibiting inflammation with myeloid cell-specific nanobiologics promotes organ transplant acceptance. Immunity. 2018;49:819-828.e6. Pubmed
  9. Busygina K, Jamasbi J, Seiler T, Deckmyn H, Weber C, Brandl R, Lorenz R, Siess W. Oral bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation. Blood. 2018;131:2605-2616 Pubmed
  10. Caporali A, Bäck M, Daemen MJ, Hoefer IE, Jones EA, Lutgens E, Matter CM, Bochaton-Piallat ML, Siekmann AF, Sluimer JC, Steffens S, Tuñón J, Vindis C, Wentzel JJ, Ylä-Herttuala S, Evans PC. Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working group on Atherosclerosis and Vascular Biology. Cardiovasc Res. 2018;114:1411-1421. Pubmed
  11. Casanova-Acebes M, Nicolás-Ávila JA, Li JL, García-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, A-González N, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, Gunzer M, Weber C, Nagasawa T, Soehnlein O, Merad M, Mortha A, Ng LG, Peinado H, Hidalgo A. Neutrophils instruct homeostatic and pathological states in naive tissues. J Exp Med. 2018;215:2778-2795 Pubmed
  12. Chevre R, Silvestre-Roig C, Soehnlein O. Nutritional Modulation of Innate Immunity: The fat-bile-gut connection. Trends Endocrinol Metab. 2018;29:686-698. Pubmed
  13. Curaj A, Wu Z, van Zandvoort M, Gresch O, Weber C, Lammers T,  Liehn EA, Kiessling F Molecular ultrasound imaging of the junctional adhesion molecule-A depicts acute changes in blood flow and its effect on endothelial activation. Arterioscler. Thromb. Vasc. Biol. 2018 Arterioscler Thromb Vasc Biol. 2018;38:40-48. Pubmed
  14. Daugherty A, Lu HS, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C. Response by Daugherty et al to Letter regarding article, "Consideration of sex differences in design and reporting of experimental arterial pathology studies: a statement from the Arteriosclerosis, Thrombosis, and Vascular Biology Council". Arterioscler Thromb Vasc Biol. 2018;38:e101-e102. Pubmed
  15. den Harder AM, de Jong PA, de Groot MCH, Wolterink JM, Budde RPJ, Iŝgum I, van Solinge WW, Ten Berg MJ, Lutgens E, Veldhuis WB, Haitjema S, Hoefer IE, Leiner T. Commonly available hematological biomarkers are associated with the extent of coronary calcifications. Atherosclerosis. 2018;275:166-173. Pubmed
  16. Dickhout A, Koenen RR. Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks. Front Cardiovasc Med. 2018;5:113. Pubmed
  17. Di Francesco A, Fedrigo M, Santovito D, Natarelli L, Castellani C, De Pascale F, Toscano G, Fraiese A, Feltrin G, Benazzi E, Nocco A, Thiene G, Valente M, Valle G, Schober A, Gerosa G, Angelini A. MicroRNA signatures in cardiac biopsies and detection of allograft rejection. J Heart Lung Transplant. 2018;37:1329-1340. Pubmed
  18. Domschke G, Linden F, Pawig L, Hafner A, Akhavanpoor M, Reymann J, Doesch AO, Erbel C, Weber C, Katus HA, Noels H, Erfle H, Gleissner CA, Runz H. Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation. Sci Rep. 2018;8:10516. Pubmed
  19. Döring Y, van der Vorst EPC. Gouty offense in patients with obstructive coronary artery disease despite state-of-the-art therapy. J Am Heart Assoc. 2018;7:e010322. Pubmed
  20. Dorn T, Kornherr J, Parrotta EI, Zawada D, Ayetey H, Santamaria G, Iop L, Mastantuono E, Sinnecker D, Goedel A, Dirschinger RJ, My I, Laue S, Bozoglu T, Baarlink C, Ziegler T, Graf E, Hinkel R, Cuda G, Kääb S, Grace AA, Grosse R, Kupatt C, Meitinger T, Smith AG, Laugwitz KL, Moretti A. Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity. EMBO J. 2018;37:e98133. Pubmed
  21. Eikendal ALM, Bots ML, Gohar A, Lutgens E, Hoefer IE, den Ruijter HM, Leiner T. Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study. J Cardiovasc Magn Reson. 2018;20:54.  Pubmed
  22. Evrard M, Kwok IWH, Chong SZ, Teng KWW, Becht E, Chen J, Sieow JL, Penny HL, Ching GC, Devi S, Adrover JM, Li JLY, Liong KH, Tan L, Poon Z, Foo S, Chua JW, Su IH, Balabanian K, Bachelerie F, Biswas SK, Larbi A, Hwang WYK, Madan V, Koeffler HP, Wong SC, Newell EW, Hidalgo A, Ginhoux F, Ng LG. Developmental analysis of bone marrow neutrophils reveals populations specialized in expansion, trafficking, and effector functions. Immunity. 2018;48:364-379. Pubmed
  23. Faller KME, Atzler D, McAndrew DJ, Zervou S, Whittington HJ, Simon JN, Aksentijevic D, Hove MT, Choe CU, Isbrandt D, Casadei B, Schneider JE, Neubauer S, Lygate CA. Impaired cardiac contractile function in AGAT knockout mice devoid of creatine is rescued by homoarginine but not creatine. Cardiovasc Res. 2018;114:417-430. Pubmed
  24. Girbl T, Lenn T, Perez L, Rolas L, Barkaway A, Thiriot A, Del Fresno C, Lynam E, Hub E, Thelen M, Graham G, Alon R, Sancho D, von Andrian UH, Voisin MB, Rot A, Nourshargh S.  Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the typical receptor ACKR1 determine discrete stages of neutrophil diapedesis. Immunity, November 13, 2018;49:1062-1076.e6. Pubmed
  25. Gómez-Moreno D, Adrover JM, Hidalgo A. Neutrophils as effectors of vascular inflammation. Eur J Clin Invest. 2018;48:e12940. Pubmed
  26. Hinkel R, Klett K, Bähr A, Kupatt C. Thymosin β4-mediated protective effects in the heart. Expert Opin Biol Ther. 2018;18:121-129. Pubmed
  27. Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard B, Neidhart M, Stroes ESG, Catapano AL, Bekkering S. Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases. Eur Heart J. 2018;39:3521-3527. Pubmed
  28. Horckmans M, Bianchini M, Santovito D, Megens RTA, Springael JY, Negri I, Vacca M, Di Eusanio M, Moschetta A, Weber C, Duchene J, Steffens S. Pericardial adipose tissue regulates granulopoiesis, fibrosis and cardiac function after myocardial infarction. Circulation. 2018;137:948-960. Pubmed
  29. Jagschies L, Hirschvogel M, Matallo J, Maier A, Mild K, Brunner H, Hinkel R, Gee MW, Radermacher P, Wildhirt SM, Hafner S. Individualized biventricular epicardial augmentation technology in a drug-induced porcine failing heart model. ASAIO J. 2018;64:480-488. Pubmed
  30. Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR. High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue. Front Physiol. 2018;9:1913. Pubmed
  31. Kusters P, Lutgens E, Seijkens TTP. Exploring immune checkpoints as potential therapeutic targets in atherosclerosis. Cardiovasc Res. 2018;114:368-377. Pubmed
  32. Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP,  Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G,Tang J, Seijkens TPP, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fischer EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R. Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates. Nat. Biomed. Eng. 2018;2:279-292. Pubmed
  33. Längin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, IButtgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjöberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schönmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht JM. Consistent success in life-supporting porcine cardiac xenotransplantation. Nature. 2018;564:430-433. Pubmed
  34. Leoni G, Soehnlein O. (Re) solving repair after myocardial infarction. Front Pharmacol. 2018;9:1342. Pubmed
  35. Lu HS, Schmidt AM, Hegele RA, Mackman N, Rader DJ, Weber C, Daugherty A. Reporting sex and sex differences in preclinical studies. Arterioscler Thromb Vasc Biol. 2018;38:e171-e184. Pubmed
  36. Maas SL, Soehnlein O and Viola JR. Organ-specific mechanisms of transendothelial neutrophil migration in the lung, liver, kidney, and aorta. Front. Immunol. 2018;9:2739. Pubmed
  37. Mederos YSM, Gudermann T, Storch U. Emerging Roles of Diacylglycerol-Sensitive TRPC4/5 Channels. Cells. 2018;7. Pubmed
  38. Natarelli L, Geißler C, Csaba G, Wei Y, Zhu M, di Francesco A, Hartmann P, Zimmer R, Schober A. miR-103 promotes endothelial maladaptation by targeting lncWDR59. Nat Commun. 2018;9:2645. Pubmed
  39. Neele AE, de Winther MPJ. Repressing the repressor: Ezh2 mediates macrophage activation. J Exp Med. 2018;275:156-165. Pubmed
  40. Neele AE, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Prange KHM, Chen HJ, Van den Bossche J, van Roomen CPPA, Shami A, Levels JHM, Kroon J, Lucas T, Dimmeler S, Lutgens E, de Winther MPJ. Myeloid Kdm6b deficiency results in advanced atherosclerosis. Atherosclerosis. 2018;275:156-165. Pubmed
  41. Nicolás-Ávila JA, Hidalgo A, Ballesteros I. Specialized functions of resident macrophages in brain and heart. J Leukoc Biol. 2018;104:743-756. Pubmed
  42. Niekamp C, Atzler D, Ojeda FM, Sinning CR, Lackner KJ, Böger RH, Munzel T, Beutel ME, Schmidtmann I, Pfeiffer N, Leuschner A, Blankenberg S, Wild PS, Zeller T, Schwedhelm E, Schnabel RB. Cross-sectional associations between homoarginine, intermediate phenotypes, and atrial fibrillation in the community-the Gutenberg Health Study. Biomolecules. 2018;8:e86. Pubmed
  43. Pacher P, Steffens S, Haskó G, Schindler TH, Kunos G. Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly. Nat Rev Cardiol. 2018;15:151-166. Pubmed
  44. Patel J, Lutgens E. Scientists on the Spot: Esther Lutgens on the immune system and atherosclerosis. Cardiovasc Res. 2018;114:e113.  Pubmed
  45. Paulin N, Viola JR, Maas SL, de Jong R, Fernandes-Alnemri T, Weber C, Drechsler M, Döring Y, Soehnlein O. Double-strand DNA sensing Aim2 inflammasome regulates atherosclerotic plaque vulnerability. Circulation. 2018;138:321-323. Pubmed
  46. Pfeiler S, Gerdes N. Atherosclerosis: cell biology and lipoproteins - focus on anti-inflammatory therapies. Curr Opin Lipidol. 2018;29:53-55. Pubmed
  47. Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C. Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. Nat Commun. 2018;9:1523. Pubmed
  48. Poller W, Dimmeler S, Heymans S, Zeller T, Haas J, Karakas M, Leistner DM, Jakob P, Nakagawa S, Blankenberg S, Engelhardt S, Thum T, Weber C, Meder B, Hajjar R, Landmesser U. Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. Eur Heart J. 2018;39:2704-2716. Pubmed
  49. Rami M, Guillamat-Prats R, Rinne P, Salvermoser M, Ring L, Bianchini M, Blanchet X, Megens RTA, Döring Y, Walzog B, Soehnlein O, Weber C, Faussner A, Steffens S. Chronic intake of the selective serotonin reuptake inhibitor Fluoxetine enhances atherosclerosis. Arterioscler Thromb Vasc Biol. 2018;38:1007-1019. Pubmed
  50. Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, Westphalen CB, Ilmer M, Valenti G, Mohanta SK, Habenicht AJR, Middelhoff M, Chu T, Nagar K, Tailor Y, Casadei R, Di Marco M, Kleespies A, Friedman RA, Remotti H, Reichert M, Worthley DL, Neumann J, Werner J, Iuga AC, Olive KP, Wang TC. β2 adrenergic-neurotrophin feedforward loop promotes pancreatic cancer. Cancer Cell. 2018;33:75-90. Pubmed
  51. Rinne P, Guillamat-Prats R, Rami M, Bindila L, Ring L, Lyytikäinen LP, Raitoharju E, Oksala N, Lehtimäki T, Weber C, van der Vorst EPC, Steffens S. Palmitoylethanolamide promotes a proresolving macrophage phenotype and attenuates atherosclerotic plaque formation. Arterioscler Thromb Vasc Biol. 2018;38:2562-2575. Pubmed
  52. Rinne P, Kadiri JJ, Velasco-Delgado M, Nuutinen S, Viitala M, Hollmén M, Rami M, Savontaus E, Steffens S. Melanocortin 1 receptor deficiency promotes atherosclerosis in apolipoprotein E-/- Mice. Arterioscler Thromb Vasc Biol. 2018;38:313-323. Pubmed
  53. Rouwet E, Lutgens E. 2016 Jeffrey M. Hoeg Award Lecture: immune checkpoints in atherosclerosis: toward immunotherapy for atheroprotection. Arterioscler Thromb Vasc Biol. 2018;38:1678-1688. Pubmed
  54. Salas-Perdomo A, Miró-Mur F, Urra X, Justicia C, Gallizioli M, Zhao Y, Brait VH, Laredo C, Tudela R, Hidalgo A, Chamorro Á, Planas AM. T Cells prevent hemorrhagic transformation in ischemic stroke by P-Selectin binding. Arterioscler Thromb Vasc Biol. 2018;38:1761-1771. Pubmed
  55. Salvermoser M, Pick R, Weckbach LT, Zehrer A, Löhr P, Drechsler M, Sperandio M, Soehnlein O, Walzog B. Myosin 1f is specifically required for neutrophil migration in 3D environments during acute inflammation. Blood.  2018;131:1887-1898. Pubmed
  56. Schmitz C, Noels H, El Bounkari O, Straussfeld E, Megens RTA, Sternkopf M, Alampour-Rajabi S, Krammer C, Tilstam PV, Gerdes N, Bürger C, Kapurniotu A, Bucala R, Jankowski J, Weber C, Bernhagen J. Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis. FASEB J. 2018;32:4428-4443. Pubmed
  57. Schönhoff M, Weineck G, Hoppe J, Hornig S, Cordts K, Atzler D, Gerloff C, Böger R, Neu A, Schwedhelm E, Choe CU. Cognitive performance of 20 healthy humans supplemented with L-homoarginine for 4 weeks. J Clin Neurosci. 2018;50:237-241. Pubmed
  58. Schumski A, Winter C, Döring Y, Soehnlein O. The ins and outs of myeloid cells in atherosclerosis. J Innate Immun. 2018;10:479-486. Pubmed
  59. Seijkens TTP, Lutgens E.Cardiovascular oncology:exploring the effects of targeted cancer therapies on atherosclerosis. Curr Opin Lipidol. 2018;29:381-388. Pubmed
  60. Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts SABM, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slütter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E.Targeting CD40-induced TRAF6 signaling in macrophages reduces atherosclerosis. J Am Coll Cardiol. 2018;71:527-542. Pubmed
  61. Soehnlein O, Bazioti V, Westerterp M. A Pad 4 plaque erosion. Circ Res. 2018;123:6-8. Pubmed
  62. Soehnlein O. Atherothrombosis : Novel therapeutic strategies. Herz. 2018;43:103-108. Pubmed
  63. Soehnlein O. Decision shaping neutrophil-platelet interplay in inflammation: from physiology to intervention. Eur J Clin Invest. 2018;48. Pubmed
  64. Steven S, Dib M, Hausding M, Kashani F, Oelze M, Kröller-Schön S, Hanf A, Daub S, Roohani S, Gramlich Y, Lutgens E, Schulz E, Becker C, Lackner KJ, Kleinert H, Knosalla C, Niesler B, Wild PS, Münzel T, Daiber A. CD40L controls obesity-associated vascular inflammation, oxidative stress and endothelial dysfunction in mice - translational aspects for man. Cardiovasc Res. 2018;114:312-323. Pubmed
  65. Stocker TJ, Pircher J, Skenderi A, Ehrlich A, Eberle C, Megens RTA, Petzold T, Zhang Z, Walzog B, Müller-Taubenberger A, Weber C, Massberg S, Ishikawa-Ankerhold H, Schulz C. The Actin regulator Coronin-1A modulates platelet shape shange and consolidates arterial thrombosis. Thromb Haemost. 2018;118:2098-2111. Pubmed

  66. Trevino-Villarreal JH, Reynolds JS, Bartelt A, Langston PK, MacArthur MR, Arduini A, Tosti V, Veronese N, Bertozzi B, Brace LE, Mejia P, Trocha K, Kajitani GS, Longchamp A, Harputlugil E, Gathungu R, Bird SS, Bullock AD, Figenshau RS, Andriole GL, Thompson A, Heeren J, Ozaki CK, Kristal BS, Fontana L, Mitchell JR. Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms. JCI Insight. 2018;3. Pubmed

  67. Tuñón J, Bäck M, Badimón L, Bochaton-Piallat ML, Cariou B, Daemen MJ, Egido J, Evans PC, Francis SE, Ketelhuth DF, Lutgens E, Matter CM, Monaco C, Steffens S, Stroes E, Vindis C, Weber C, Hoefer IE; ESC Working Group on Atherosclerosis and Vascular Biology. Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice. Eur J Prev Cardiol. 2018;25:948-955. Pubmed
  68. Vajen T, Koenen RR, Werner I, Staudt M, Projahn D, Curaj A, Sönmez TT, Simsekyilmaz S, Schumacher D, Möllmann J, Hackeng TM, Hundelshausen PV, Weber C, Liehn EA. Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Sci Rep. 2018;8:10647. Pubmed
  69. van der Tuin SJL, Li Z, Berbée JFP, Verkouter I, Ringnalda LE, Neele AE, van Klinken JB, Rensen SS, Fu J, de Winther MPJ, Groen AK, Rensen PCN, Willems van Dijk K, Wang Y. Lipopolysaccharide lowers cholesteryl ester transfer protein by activating F4/80+Clec4f+Vsig4+Ly6C- kupffer cell subsets. J Am Heart Assoc. 2018;7:e008105. Pubmed
  70. van der Vorst EPC, de Jong RJ, Donners MMPC. Message in a microbottle: modulation of vascular inflammation and atherosclerosis by extracellular vesicles. Front Cardiovasc Med. 2018;22:5-2. Pubmed
  71. van der Vorst EPC, Döring Y. Resistin keeps its Janus face. Int J Cardiol. 2018;272:47-48.  Pubmed
  72. van der Vorst EPC, Weber C, Donners MMPC. A disintegrin and metalloproteases (ADAMs) in cardiovascular, metabolic and inflammatory diseases: aspects for theranostic approaches. Thromb Haemost. 2018;118:1167-1175. Pubmed
  73. van der Vorst EPC, Weber C. Metabolomic profiling of atherosclerotic plaques: towards improved cardiovascular risk stratification. Eur Heart J. 2018;39:2311-2313. Pubmed
  74. Vinketova К, Karagyozov I, Koleva V, Hristov M, Mourdjeva M, Sperandio M, Oreshkova T. Progesterone and cyclic adenosine monophosphate down-regulate CD90 in the stromal cells of human decidua. In vitro evidence and in situ findings. Am J Reprod Immunol. 2018 Nov;80(5):e13043. Pubmed
  75. Viola JR, Lemnitzer P, Paulin N, Drechsler M, Nazari-Jahantigh M, Maas S, De Jong RJ, Winter J, Schober A, Weber C, Atabai K, Soehnlein O. Deletion of MFGE8 inhibits neointima formation upon arterial damage. Thromb Haemost. 2018;118:1340-1342. Pubmed
  76. Wang W, Liu W, Fidler T, Wang Y, Tang Y, Woods B, Welch C, Cai B, Silvestre-Roig C, Ai D, Yang YG, Hidalgo A, Soehnlein O, Tabas I, Levine RL, Tall AR, Wang N. Macrophage inflammation, erythrophagocytosis, and accelerated atherosclerosis in Jak2 V617F Mice. Circ Res. 2018;123:e35-e47. Pubmed
  77. Wei Y, Corbalán-Campos J, Gurung R, Natarelli L, Zhu M, Exner N, Erhard F, Greulich F, Geißler C, Uhlenhaut NH, Zimmer R, Schober A. Dicer in macrophages prevents atherosclerosis by promoting mitochondrial oxidative metabolism. Circulation 2018;138:2007-2020. Pubmed
  78. Wei Y, Zhu M, Schober A. Macrophage microRNAs as therapeutic targets for atherosclerosis, metabolic syndrome, and cancer. Int J Mol Sci. 2018;19:e1756 Pubmed
  79. Williams JW, Martel C, Potteaux S, Esaulova E, Ingersoll MA, Elvington A, Saunders BT, Huang LH, Habenicht AJ, Zinselmeyer BH, Randolph GJ. Limited macrophage positional dynamics in progressing or regressing murine atherosclerotic plaques. Arterioscler Thromb Vasc Biol. 2018;38:1702-1710. Pubmed
  80. Winter C, Silvestre-Roig C, Ortega-Gomez A, Lemnitzer P, Poelman H, Schumski A, Winter J, Drechsler M, de Jong R, Immler R, Sperandio M, Hristov M, Zeller T, Nicolaes GAF, Weber C, Viola JR, Hidalgo A, Scheiermann C, Soehnlein O. Chrono-pharmacological targeting of the CCL2-CCR2 axis ameliorates atherosclerosis. Cell Metab. 2018;28:175-182.e5. Pubmed
  81. Winter C, Soehnlein O, Maegdefessel L. TIMPing the aorta: smooth muscle cell-specific deletion of BMAL1 limits murine abdominal aortic aneurysm development. Arterioscler Thromb Vasc Biol. 2018;38:982-983. Pubmed
  82. Winter C, Soehnlein O. The potential of chronopharmacology for treatment of atherosclerosis. Curr Opin Lipidol. 2018;29:368-374. Pubmed
  83. Zhou Z, Schober A, Nazari-Jahantigh M. Dicer promotes endothelial recovery and limits lesion formation after vascular injury through miR-126-5p. Int J Cardiol. 2018;273:199-202. Pubmed
  84. Ziegler T, Bähr A, Howe A, Klett K, Husada W, Weber C, Laugwitz KL, Kupatt C, Hinkel R.Tβ4 increases neovascularization and cardiac function in chronic myocardial ischemia of normo- and hypercholesterolemic pigs. Mol Ther. 2018;26:1706-1714. Pubmed
  85. Ziegler T, Hinkel R, Kupatt C. Induced pluripotent stem cell derived cardiac models: effects of Thymosin β4. Expert Opin Biol Ther. 2018;18:111-120. Pubmed
  86. Ziegler T, Kraus M, Husada W, Gesenhues F, Jiang Q, Pinkenburg O, Trenkwalder T, Laugwitz KL, le Noble F, Weber C, Kupatt C, Hinkel R. Steerable induction of the thymosin ß4/MRTF-A pathway via AAV-based overexpression induces therapeutic neovascularization. Hum Gene Ther. 2018;28:1407–1415. Pubmed
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Direktor:

Prof. Dr. med. Christian Weber

Institute for Cardiovascular Prevention (IPEK)

 

Pettenkoferstraße 8a & 9

80336 München

 

Tel.: 089-4400-54351

Fax: 089-4400-54352

Mail: ipek.office@med.lmu.de