2016

 

  1. Alam A, Leoni G, Quiros M, Wu H, Desai C, Nishio H, Jones RM, Nusrat A, Neish AS. The microenvironment of injured murine gut elicits a local pro-restitutive microbiota. Nat Microbiol. 2016;1:15021. Pubmed
  2. Bamberg F, Hetterich H, Rospleszcz S, Lorbeer R, Auweter SD, Schlett CL, Schafnitzel A, Bayerl C, Schindler A, Saam T, Müller-Peltzer K, Sommer W, Zitzelsberger T, Machann J, Ingrisch M, Selder S, Rathmann W, Heier M, Linkohr B, Meisinger C, Weber C, Ertl-Wagner B, Massberg S, Reiser MF, Peters A. Subclinical disease burden as assessed by whole-body MRI in subjects with prediabetes, subjects with diabetes, and normal control subjects from the general population:the KORA-MRI study. Diabetes. 2016;66:158-169. Pudmed
  3. Braster Q, Silvestre-Roig C, Hartwig H, Kusters P, Aarts S, den Toom M, Gallo RL, Weber C, Lutgens E, Soehnlein O. Cathelicidin regulates myeloid cell accumulation in adipose tissue and promotes insulin resistance during obesity. Thromb Haemost. 2016;115:1237-9. Pubmed
  4. Braster Q, Silvestre Roig C, Hartwig H, Beckers L, den Toom M, Döring Y, Daemen MJ, Lutgens E, Soehnlein O. Inhibition of nET release fails to reduce adipose tissue inflammation in mice. PLoS One. 2016;11:e0163922. Pubmed
  5. Campa CC, Germena G, Ciraolo E, Copperi F, Sapienza A, Franco I, Ghigo A, Camporeale A, Di SavinoA, Martini M, Perino A, Megens RT, Kurz AR, Scheiermann C, Sperandio M, Gamba A, Hirsch E. Rac signal adaptation controls neutrophil mobilization from the bone marrow. Sci Signal. 2016;20:9. Pubmed
  6. Chong SZ, Evrard M, Devi S, Chen J, Lim JY, See P, Zhang Y, Adrover JM, Lee B, Tan L, Li JL, Liong KH, Phua C, Balachander A, Boey A, Liebl D, Tan SM, Chan JK, Balabanian K, Harris JE, Bianchini M, Weber C, Duchene J, Lum J, Poidinger M, Chen Q, Rénia L, Wang CI, Larbi A, Randolph GJ, Weninger W, Looney MR, Krummel MF, Biswas SK, Ginhoux F, Hidalgo A, Bachelerie F, Ng LG. CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses. J Exp Med. 2016;213:2293-2314.  Pubmed
  7. Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T. Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. eLife. 2016;5:e20914. Pubmed
  8. Daugherty A, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C. Complying with the national institutes of health guidelines and principles for rigor and reproducibility: refutations. Arterioscler Thromb Vasc Biol. 2016;36:1303-4. Pubmed
  9. de Jong RJ, Leoni G, Drechsler M, Soehnlein O. The advantageous role of annexin A1 in cardiovascular disease.Cell Adh Migr. 2016;18:1-14. Pubmed
  10. Deppe J, Popp T, Egea V, Steinritz D, Schmidt A, Thiermann H, Weber C, Ries C. Impairment of hypoxia-induced HIF-1α signaling in keratinocytes and fibroblasts by sulfur mustard is counteracted by a selective PHD-2 inhibitor. Arch Toxicol. 2016;90:1141-50. Pubmed
  11. Deppe J, Steinritz D, Santovito D, Egea V, Schmidt A, Weber C, Ries C. Upregulation of miR-203 and miR-210 affect growth and differentiation of keratinocytes after exposure to sulfur mustard in normoxia and hypoxia. Toxicol Lett. 2016;244:81-7. Pubmed
  12. Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Müller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sánchez-Garrido MA, Liu P, Tuckermann J, Malehmir M, Healy ME, Weber A, Heikenwalder M, Jastroch M, Kleinert M, Jall S, Brandt S, Flamant F, Schramm KW, Biebermann H, Döring Y, Weber C, Habegger KM, Keuper M, Gelfanov V, Liu F, Köhrle J, Rozman J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Hofmann SM, Yang B, Tschöp MH, DiMarchi R, Müller TD. Chemical hybridization of glucagon and thyroid hormone opotimizes therapeutic impact for metabolic disease. Cell. 2016;20:843-857. Pubmed
  13. Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP. Regulation of monocyte cell fate by blood vessels mediated by notch signalling. Nat Commun. 2016;31:7-12. Pubmed
  14. Gerdes N, Seijkens T, Lievens D, Kuijpers MJ, Winkels H, Projahn D, Hartwig H, Beckers L, Megens RT, Boon L, Noelle RJ, Soehnlein O, Heemskerk JW, Weber C, Lutgens E. Platelet CD40 exacerbates atherosclerosis by transcellular activation of endothelial cells and leukocytes. Arterioscler Thromb Vasc Biol. 2016;36:482-90. Pubmed
  15. Hartmann D, Fiedler J, Sonnenschein K, Just A, Pfanne A, Zimmer K, Remke J, Foinquinos A, Butzlaff M, Schimmel K, Maegdefessel L, Hilfiker-Kleiner D, Lachmann N, Schober A, Froese N, Heineke J, Bauersachs J, Batkai S, Thum T. MicroRNA-based therapy of gata2-deficient vascular disease. Circulation. 2016;13:1973-1990. Pubmed
  16. Hartmann P, Zhou Z, Natarelli L, Wei Y, Nazari-Jahantigh M, Zhu M, Grommes J, Steffens S, Weber C, Schober A. Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4. Nat Commun. 2016;7:10521. Pubmed
  17. Hibender S, Franken R, van Roomen C, Ter Braake A, van der Made I, Schermer EE, Gunst Q, van den Hoff MJ, Lutgens E, Pinto YM, Groenink M, Zwinderman AH, Mulder BJ, de Vries CJ, de Waard V. Resveratrol inhibits aortic root dilatation in the Fbn1C1039G/+ marfan mouse model. Arterioscler Thromb Vasc Biol. 2016;36:1618-26. Pubmed
  18. Hu D, Yin C, Mohanta SK, Weber C, Habenicht AJ. Preparation of single cell suspensions from mouse aorta. Bio Protoc. 2016;11:5-7.  Pubmed
  19. Jamasbi J, Megens R, Bianchini M, Uhland K, Münch G, Ungerer M, Sherman S, Faussner A, Brandl R, John C, Buchner J, Weber C, Lorenz R, Elia N, Siess W. Cross-linking GPVI-Fc by anti-fc antibodies potentiates its inhibition of atherosclerotic plaque- and collagen-iInduced platelet activation. Basic to Translational Science. 2016;25:142-13. Pubmed
  20. Jansen MF, Hollander MR, van Royen N, Horrevoets AJ, Lutgens E. CD40 in coronary artery disease: a matter of macrophages? Basic Res Cardiol. 2016;111:38. Pubmed
  21. Leiva M, Quintana JA, Ligos JM, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;8;7-10. Pubmed
  22. Leiva M, Hidalgo A. Bidirectional dialog in the haematopoietic niche. Cell Cycle. 2016;15:1027-8. Pubmed
  23. Li J, McArdle S, Gholami A, Kimura T, Wolf D, Gerhardt T, Miller J, Weber C, Ley K. CCR5+T-bet+FoxP3+ Effector CD4 T cells drive atherosclerosis. Circ Res. 2016;13:1540-52. Pubmed
  24. Lip GY, Weber C. May your New Year be happy and prosperous with "Thrombosis and Haemostasis". Thromb Haemost. 2015;115:1-2. Pubmed
  25. Mahl C, Egea V, Megens RT, Pitsch T, Santovito D, Weber C, Ries C. RECK (reversion-inducing cysteine-rich protein with Kazal motifs) regulates migration, differentiation and Wnt/β-catenin signaling in human mesenchymal stem cells. Cell Mol Life Sci. 2016;73:1489-501. Pubmed
  26. Martínez-Moreno M, Leiva M, Aguilera-Montilla N, Sevilla-Movilla S, Isern de Val S, Arellano-Sánchez N, Gutiérrez NC, Maldonado R, Martínez-López J, Buño I, García-Marco JA, Sánchez-Mateos P, Hidalgo A, García-Pardo A, Teixidó J. In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by α4β1 cytoplasmic-binding proteins. Leukemia. 2016;30:861-72. Pubmed
  27. Meiler S, Smeets E, Winkels H, Shami A, Pascutti FM, Nolte MA, Beckers L, Weber C, Gerdes N, Lutgens E. Constitutive GITR activation reduces atherosclerosis by promoting regulatory CD4+ T-Cell responses. Arterioscler Thromb Vasc Biol. 2016;36:1748-52. Pubmed
  28. Mohanta S, Yin C, Weber C, Hu D, Habenicht AJ. Aorta atherosclerosis lesion analysis in hyperlipidemic mice. Bio Protoc. 2016;6.pii:e1832. Pubmed
  29. Mühlstedt S, Ghadge SK, Duchene J, Qadri F, Järve A, Vilianovich L, Popova E, Pohlmann A, Niendorf T, Boyé P, Özcelik C, Bader M.  Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction. J Mol Med. 2016;94:1005-14. Pubmed
  30. Nus M, Martínez-Poveda B, MacGrogan D, Chevre R, D'Amato G, Sbroggio M, Rodríguez C, Martínez-González J, Andrés V, Hidalgo A, de la Pompa JL. Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis. Cardiovasc Res. 2016;12:568–580. Pubmed
  31. Ortega Gomez A, Salvermoser M, Rossaint J, Pick R, Brauner J, Lemnitzer P, Tilgner J, de Jong R, Megens RT, Jamasbi J, Döring Y, Pham CT, Scheiermann C, Siess W, Drechsler M, Weber C, Grommes J, Zarbock A, Walzog B, Soehnlein O. Cathepsin G controls arterial but not venular myeloid cell recruitment. Circulation. 2016;18;1176-1188. Pubmed
  32. Petzold T, Thienel M, Konrad I, Schubert I, Regenauer R, Hoppe B, Lorenz M, Eckart A, Chandraratne S, Lennerz C, Kolb C, Braun D, Jamasbi J, Brandl R, Braun S, Siess W, Schulz C, Massberg S. Oral thrombin inhibitor aggravates platelet adhesion and aggregation during arterial thrombosis. Sci Transl Med. 2016;8:367-68. Pubmed
  33. Rajasekaran D, Gröning S, Schmitz C, Zierow S, Drucker N, Bakou M, Kohl K, Mertens A, Lue H, Weber C, Xiao A, Luker G, Kapurniotu A, Lolis EJ, Bernhagen J. Macrophage migration inhibitory factor-CXCR4 receptor interactions: evidence for partial allosteric agonism in comparsion to CXCL12.  Biol Chem. 2016;22:15881-95. Pubmed
  34. Santovito D, Egea V, Weber C. Small but smart: MicroRNAs orchestrate atherosclerosis development and progression. Biochim Biophys Acta. 2016;1861:2075-2086. Pubmed
  35. Santovito D, Weber C. Zooming in on microRNAs for refining cardiovascular risk prediction in secondary prevention. Eur Heart J. 2016;117:231-237. Pubmed
  36. Schaftenaar F, Frodermann V, Kuiper J, Lutgens E. Atherosclerosis: the interplay between lipids and immune cells. Curr Opin Lipidol. 2016;27:209-15. Pubmed 
  37. Schloss MJ, Horckmans M, Nitz K, Duchene J, Drechsler M, Bidzhekov K, Scheiermann C, Weber C, Soehnlein O, Steffens S.  The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment. EMBO Mol Med. 2016;8:937-48. Pubmed
  38. Schmohl J, Santovito D, Guenther T, Sutanto W, Kroell T, Salih H, Pitsch T, Egea V, Weber C, Schmetzer H, Ries C. Expression of surface-associated 82kDa-proMMP-9 in primary acute leukemia blast cells inversely correlates with patients' risk. Exp Hematol. 2016;44:358-362. Pubmed
  39. Schober A, Weber C. Mechanisms of microRNAs in atheroscleosis. Annu Rev Pathol. 2016;11:583-616. Pubmed
  40. Silvestre-Roig C, Hidalgo A, Soehnlein O. Neutrophil heterogeneity: implications for homeostasis and pathogenesis. Blood. 2016;127:2173-81. Pubmed
  41. Simsekyilmaz S, Liehn EA, Weinandy S, Schreiber F, Megens RT, Theelen W, Smeets R, Jockenhövel S, Gries T, Möller M, Klee D, Weber C, Zernecke A. Trageting in-stent-stenosis with Rgd- and Cxcl1- coated mini-stents in mice. PLoS One. 2016;11:e0155829. Pubmed
  42. Soehnlein O. Monocytes Chat With Atherosclerotic Lesions.  Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1720-1. Pubmed
  43. Spitz C, Winkels H, Bürger C, Weber C, Lutgens E, Hansson GK, Gerdes N. Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential. Cell Mol Life Sci. 2016;73:901-22. Pubmed
  44. Spronck B, Megens RT, Reesink KD, Delhaas T. A method for three-dimensional quantification of vascular smooth muscle orientation: application in viable murine carotid arteries. Biomech Model Mechanobiol.  2016;15:419-32. Pubmed
  45. Srikakulapu P, Hu D, Yin C, Mohanta SK, Vineela Bontha S, Peng L, Beer M, Weber C, McNamara CA, Grassia G, Maffia P, Manz RA, Habenicht AJ. Artery tertiary lymphoid organs control multilayered territorialized atherosclerosis B-cell responses in aged Apoe-/- mice. Arterioscler Thromb Vasc Biol. 2016;36:1174-1185. Pubmed
  46. Steffens S, M1 signature mediators in atheroma-derived single cell secretome of symptomatic plaques. Insight … inflammatory pathways activated within instable plaques which promote a pro-inflammatory M1 macrophage polarisation. Thromb Haemost. 2016;2;115:871. Pubmed
  47. Tilgner J, von Trotha KT, Gombert A, Jacobs MJ, Drechsler M, Döring Y, Soehnlein O, Grommes J. Aspirin but not tirofiban displays protective effects in endotoxin induced lung injury. PLoS One. 2016; 1;11-12. Pubmed
  48. van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MP, Lütjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PC, Berbée JF. BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice. Atherosclerosis. 2016;251:6-14. Pubmed
  49. van der Vorst EP, Theodorou K, Wu Y, Hoeksema MA, Goossens P, Bursill CA, Aliyev T, Huitema LF, Tas SW, Wolfs IM, Kuijpers 
  50. Viola J, Lemnitzer P, Jansen Y, Csaba G, Winter C, Neideck C, Silvestre-Roig C, Dittmar G, Döring Y, Drechsler M, Weber C, Zimmer R, Cenac N, Soehnlein O. Resolving lipid mediators maresin 1 and resolvin D2 prevent atheroprogression in mice. Circ Res. 2016;119:1030-1038. Pubmed
  51. Viola J, Soehnlein O. Atherosclerosis - A matter of unresolved inflammation. Semin Immunol. 2016;27:184-93. Pubmed
  52. Weber C, Döring Y, Noels H. Potential cell-specific functions of CXCR4 in atherosclerosis. Hamostaseologie. 2016;10:97-102. Pubmed
  53. Weber C, Shantsila E, Hristov M, Caligiuri G, Guzik T, Heine GH, Hoefer IE, Monaco C, Peter K, Rainger E, Siegbahn A, Steffens S, Wojta J, Lip GY. Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the european society of cardiology (ESC) working groups "Atherosclerosis & Vascular Biology" and "Thrombosis". Thromb Haemost. 2016;27:626-37. Pubmed
  54. Wei Y, Schober A. MicroRNA regulation of macrophages in human pathologies. Cell Mol Life Sci. 2016;73:3473-95. Pubmed
  55. Wichapong K, Alard JE, Ortega-Gomez A, Weber C, Hackeng TM, Soehnlein O, Nicolaes GA. Structure-based design of peptidic inhibitors of the interaction between chemokine 5 (CCL5) and human neutrophil peptides 1 (HNP1). J Med Chem. 2016;59:4289-301. Pubmed
  56. Yin C, Mohanta SK, Srikakulapu P, Weber C, Habenicht AJ. Artery tertiary lymphoid organs: powerhouses of atherosclerosis immunity.Review article Front Immunol. 2016;7:387. Pubmed
  57. Ziegler T, Horstkotte M, Lange P, Ng J, Bongiovanni D, Hinkel R, Laugwitz KL, Sperandio M, Horstkotte J, Kupatt C. Endothelial RAGE exacerbates acute postischaemic cardiac inflammation. Thromb Haemost. 2016;116:300-8. Pubmed

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