2012

  1. Bampalis VG, Annette Brantl S, Siess W. Why and how to eliminate spontaneous platelet aggregation in blood measured by multiple electrode aggregometry. J Thromb Haemost. 2012;10:1710-4. Pubmed
  2. Bidzhekov K, Gan L, Denecke B, Rostalsky A, Hristov M, Koeppel TA, Zernecke A, Weber C. microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans. Thromb Haemost. 2012;107:619-25.  Pubmed
  3. Blanchet X, Langer M, Weber C, Koenen RR, von Hundelshausen P. Touch of Chemokines. Front Immunol. 2012;3:175. Pubmed
  4. Bras G, Bochenska O, Rapala-Kozik M, Guevara-Lora I, Faussner A, Kozik A: Extracellular aspartic protease SAP2 of Candida albicans yeast cleaves human kininogens and releases proinflammatory peptides, Met-Lys-bradykinin and des-Arg9-Met-Lys-bradykinin. Biol Chem. 2012;393:829-39. Pubmed
  5. Brauner R, Johannes C, Ploessl F, Bracher F, Lorenz RL. Phytosterols reduce cholesterol absorption by inhibition of 27-hydroxycholesterol generation, liver X receptor α activation, and expression of the basolateral sterol exporter ATP-binding cassette A1 in Caco-2 enterocytes. J Nutr. 2012;142:981-9. Pubmed
  6. Cardilo-Reis L, Gruber S, Schreier SM, Drechsler M, Papac-Milicevic N, Weber C, Wagner O, Stangl H, Soehnlein O, Binder CJ. Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype. EMBO Mol Med. 2012;4:1072-86. Pubmed
  7. Djafarzadeh R, Sauter M, Notohamiprodjo S, Noessner E, Goyal P, Siess W, Wörnle M, Ribeiro A, Himmelein S, Sitter T, Nelson PJ. Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. PLoS One.2012;7:e33963. Pubmed
  8. Döring Y, Zernecke A. Plasmacytoid Dendritic Cells in Atherosclerosis. Front Physiol. 2012;3:230.  Pubmed
  9. Döring Y, Soehnlein O, Drechsler M, Shagdarsuren E, Chaudhari S, Meiler S, Hartwig H, Hristov M, Koenen RR, Hieronymus T, Zenke M, Weber C, Zernecke A. Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol. 2012;32:1613-23. Pubmed
  10. Döring Y, Drechsler M, Wantha S, Kemmerich K, Lievens D, Vijayan S, Gallo RL, Weber C, Soehnlein O. Lack of Neutrophil-Derived CRAMP Reduces Atherosclerosis in Mice. Circ. Res. 2012;110:1052-6. Pubmed
  11. Döring Y, Manthey H, Drechsler M, Lievens D, Megens RTA, Soehnlein O, Busch M, Manca M, Koenen RR, Pelisek J,  Daemen MJ, Lutgens E, Zenke M,  Binder CJ, Weber C, Zernecke A. Auto-antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis. Circulation 2012;125:1673-83. Pubmed
  12. Döring Y, Noels H, Weber C. The use of high-throughput technologies to investigate vascular inflammation and atherosclerosis.Arterioscler Thromb Vasc Biol. 2012;32:182-95. Pubmed
  13. Egea V, Schober A, Weber C. Circulating miRNAs: messengers on the move in cardiovascular disease. Thromb Haemost. 2012;108:590-1  Pubmed
  14. Egea V, Zahler S, Rieth N, Neth P, Popp T, Kehe K, Jochum M, Ries C. Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling. Proc Natl Acad Sci USA 2012;109:e309-16. Pubmed
  15. Faussner A, Schüssler S, Feierler J, Bermudez M, Pfeifer J, Schnatbaum K, Tradler T, Jochum M, Wolber G, Gibson C.: Binding characteristics of [(3) H]-JSM10292: a new cell membrane-permeant non-peptide bradykinin B(2) receptor antagonist. Br J Pharmacol. 2012;167:839-53.  Pubmed
  16. Grommes J, Alard JE, Drechsler M, Wantha S, Mörgelin M, Kuebler WM, Jacobs M, von Hundelshausen P, Markart P, Wygrecka M, Preissner KT, Hackeng TM, Koenen RR, Weber C, Soehnlein O. Disruption of Platelet-derived Chemokine Heteromers Prevents Neutrophil Extravasation in Acute Lung Injury. Am J Respir Crit Care Med 2012;185:628-36. Pubmed
  17. Grismayer B, Sato S, Kopitz C, Ries C, Soelch S, Schmitt M, Baretton G, Krüger A, Luther T, Kotzsch M, Magdolen V. Overexpression of the urokinase receptor splice variant uPAR-del4/5 in breast cancer cells affects cell adhesion and invasion in a dose-dependent manner and modulates transcription of tumor-associated genes. Biol Chem. 2012;393:1449–1455. Pubmed
  18. Grommes J, Mörgelin M, Soehnlein O. Pioglitazone attenuates endotoxin induced acute lung injury by reducing neutrophil recruitment. Eur Respir J.2012;40:416-423. Pubmed
  19. Grommes J, Vijayan S, Drechsler M, Hartwig H, Mörgelin M, Dembinski R, Jacobs M, Koeppel TA, Binnebösel M, Weber C, Soehnlein O. Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation. PLoS One. 2012;7:e38917.Pubmed
  20. Hamesch K, Subramanian P, Li X, Dembowsky K, Chevalier E, Weber C, Schober A. The CXCR4 antagonist POL5551 is equally effective as sirolimus in reducing neointima formation without impairing re-endothelialisation. Thromb Haemost 2012;107:356-68. Pubmed
  21. Hristov M, Schmitz S, Nauwelaers F, Weber C. A flow cytometric protocol for enumeration of endothelial progenitor cells and monocyte subsets in human blood. J Immunol Methods 2012;381:9-13. Pubmed
  22. Kamchybekov U, Figulla HR, Gerdes N, Jung C. Macrophage migration inhibitory factor is elevated in obese adolescents. Arch Physiol Biochem. 2012;118:204-9. Pubmed
  23. Kanzler I, Liehn EA, Koenen RR, Weber C. Anti-inflammatory therapeutic approaches to reduce acute atherosclerotic complications. Curr Pharmaceut Biotechnol 2012;13(1):37-45. Pubmed
  24. Karshovska E, Weber C. Atherosclerosis: cell biology and lipoproteins - New mechanistic links in atherosclerosis: chemokines mediating the effects of lipids, platelets and dendritic cells. Curr Opin Lipidol. 2012;23:400-1. Pubmed
  25. Koenen RR, Weber C (2012) Chemokines as therapeutic targets of atherosclerosis. In Atherosclerosis:  Treatment and Prevention, edited by C. Weber & O. Söhnlein, Pan Stanford Publishing. ISBN: 978-981-4316-26-2. Link
  26. Kolben T, Peröbner I, Fernsebner K, Lechner F, Geissler C, Ruiz-Heinrich L, Capovilla S, Jochum M, Neth P. Dissecting the impact of Frizzled receptors in Wnt/β-catenin signaling of human mesenchymal stem cells. Biol Chem. 2012;393(12):1433-47 Pubmed
  27. Liehn E, Bucur O, Weber C. Role of Microparticles as Messengers Enhancing Stem Cell Activity After Genetic Engineering. Circ Res. 2012;111:265-267. Pubmed
  28. Lip GY, Weber C. Welcome to a new year in Thrombosis and Haemostasis. Thromb Haemost 2012;107:1-2. Link
  29. Lutgens E, Leiner T, Weber C. RANK(L)-ing biomarkers as surrogates for coronary calcium score. Thromb Haemost 2012;107:3. Pubmed
  30. Matusik P, Guzik B, Weber C, Guzik TJ. Do we know enough about the immune pathogenesis of acute coronary syndromes to improve clinical practice? Thromb Haemost. 2012;108:443-56. Pubmed
  31. Megens RT, Vijayan S, Lievens D, Doering Y, van Zandvoort MA, Grommes J, Weber C, Soehnlein O. Presence of luminal neutrophil extracellular traps in atherosclerosis. Thromb Haemost 2012;107:597-8. Pubmed
  32. Nazari-Jahantigh M, Wei Y, Noels H, Akhtar S, Zhou Z, Koenen RR, Heyll K, Gremse F, Kiessling F, Grommes J, Weber C, Schober A.J MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. J Clin Invest. 2012;22:4190-202 Pubmed
  33. Nazari-Jahantigh M, Wei Y, Schober A. The role of microRNAs in arterial remodelling. Thromb Haemost. 2012;107(4):611-8. Pubmed
  34. Noels H, Bernhagen J, Weber C (2012) MIF in atherosclerosis. In The MIF Handbook, p. 321-346, edited by R. Bucala, World Scientific Publishing. ISBN: 978-981-4335-35-5 Link
  35. Peröbner I, Karow M, Jochum M, Neth P. LRP6 mediates Wnt/β-catenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells. Int J Biochem Cell Biol. 2012 ;44:1970-82. Pubmed
  36. Postea O, Vasina EM, Cauwenberghs S, Projahn D, Liehn EA, Lievens D, Theelen W, Kramp BK, Dragomir Butoi E, Soehnlein O, Heemskerk JW, Ludwig A, Weber C, Koenen RR. Contribution of Platelet CX3CR1 to Platelet-Monocyte Complex Formation and Vascular Recruitment During Hyperlipidemia. Arterioscler Thromb Vasc Biol.2012;32:1186-93.Pubmed
  37. Poti F, Costa S, Bergonzini V, Galletti M, Pignatti E, Weber C, Simoni M, Nofer JR. Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R(-/-)) mice. Vascul Pharmacol. 2012;57:56-64. Pubmed
  38. Projahn D, Koenen RR. Platelets: key players in vascular inflammation. J Leukoc Biol. 2012;92:1167-75. Pubmed
  39. Raffetseder U, Liehn EA, Weber C, Mertens PR. Role of cold shock Y-box protein-1 in inflammation, atherosclerosis and organ transplant rejection. Eur J Cell Biol 2012;91:567-75. Pubmed
  40. Redondo S, González-Rocafort A, Navarro-Dorado J, Ramajo M, Hristov M, Gordillo-Moscoso A, Reguillo F, Carnero M, Martinez-Gonzalez J, Rodríguez E, Weber C, Tejerina T. Decreased pre-surgical CD34+/CD144+ cell number in patients undergoing coronary artery bypass grafting compared to coronary artery disease-free valvular patients. J Cardiothorac Surg. 2012;7:2. Pubmed
  41. Rohwedder I, Montanez E, Beckmann K, Bengtsson E, Dunér P, Nilsson J, Soehnlein O, Fässler R. Plasma fibronectin deficiency impedes atherosclerosis progression and fibrous cap formation. EMBO Mol Med. 2012;4:564-76. Pubmed
  42. Rowinska Z, Zander S, Zernecke A, Jacobs M, Langer S, Weber C, Merx MW, Koeppel TA. Non-invasive in vivo analysis of a murine aortic graft using high reslolution ultrasound microimaging. Eur J Radiol 2012;81:244-49. Pubmed
  43. Schober A, Siess W. Lysophosphatidic acid in atherosclerotic diseases. Br J Pharmacol. Br J Pharmacol. 2012;167:465-82. Pubmed
  44. Schuh A, Kroh A, Konschalla S, Liehn EA, Sobota RM, Biessen EA, Bot I, Sönmez T, Schober A, Marx N, Weber C, Sasse A. Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model. J Cell Mol Med. 2012;16:2311-20. Pubmed
  45. Schuh A, Sasse A, Konschalla S, Kroh A, Merx MW, Weber C, Liehn EA. Repetitive transplantation of different cell types sequentially improves heart function after infarction. J Cell Mol Med 2012;16:1640-1647. Pubmed
  46. Schwartz V, Krüttgen A, Weis J, Weber C, Ostendorf T, Lue H, Bernhagen J. Role for CD74 and CXCR4 in clathrin-dependent endocytosis. Eur J Cell Biol 2012;91:435-449. Pubmed
  47. Soehnlein O. Multiple roles for neutrophils in atherosclerosis. Circ Res. 2012;110:875-88. Pubmed
  48. Soehnlein O, Weber C (2012) Neutrophils and their granule proteins in the treatment of athero-sclerosis. In Atherosclerosis: Treatment and Prevention, edited by C. Weber & O. Söhnlein, Pan Stanford Publishing. ISBN: 978-981-4316-26-2 Link
  49. Stöger JL, Gijbels MJ, van der Velden S, Manca M, van der Loos CM, Biessen EA, Daemen MJ, Lutgens E, de Winther MP :Distribution of macrophage polarization markers in human atherosclerosis. Atherosclerosis. 2012;225:461-8. Pubmed
  50. Van de Vijver P, Schmitt M, Suylen D, Scheer L, Thomassen MC, Schurgers LJ, Griffin JH, Koenen RR, Hackeng TM. Incorporation of Disulfide Containing Protein Modules into Multivalent Antigenic Conjugates: Generation of Antibodies against the Thrombin-Sensitive Region of Murine Protein S. J Am Chem Soc. 2012;134:19318-21. Pubmed
  51. Weber C, Lip GY. Highlights and hot topics from 2011 in Thrombosis and Haemostasis. Thromb Haemost 2012;107:196-9. Link
  52. Zernecke A, Weber C. Improving the treatment of atherosclerosis by linking anti-inflammatory and lipid modulating strategies. Heart. 2012;98:1600-6. Pubmed
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