2021

  1. Abdel Rahman F, d'Almeida S, Zhang T, Asadi M, Bozoglu T, Bongiovanni D, von Scheidt M, Dietzel S, Schwedhelm E, Hinkel R, Laugwitz KL, Kupatt C, Ziegler T. Sphingosine-1-Phosphate Attenuates Lipopolysaccharide-Induced Pericyte Loss via Activation of Rho-A and MRTF-A. Thromb Haemost. 2021;121:341-350. Pubmed
  2. Alexander Y, Osto E, Schmidt-Trucksass A, Shechter M, Trifunovic D, Duncker DJ, Aboyans V, Back M, Badimon L, Cosentino F, De Carlo M, Dorobantu M, Harrison DG, Guzik TJ, Hoefer I, Morris PD, Norata GD, Suades R, Taddei S, Vilahur G, Waltenberger J, Weber C, Wilkinson F, Bochaton-Piallat ML, Evans PC. Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis. Cardiovasc Res. 2021;117:29-42. Pubmed
  3. Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen-Woods C, Reglero-Real N, Stein M, Vazquez-Martinez L, Girbl T, Poston RN, Golding M, Saleeb RS, Thiriot A, von Andrian UH, Duchene J, Voisin MB, Bishop CL, Voehringer D, Roers A, Rot A, Lammermann T, Nourshargh S. Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity. 2021;54:1494-1510 e1497. Pubmed
  4. Bernlochner I, Klug M, Larasati D, Von Scheidt M, Santovito D, Hristov M, Weber C, Laugwitz KL, Bongiovanni D. Sorting and magnetic-based isolation of reticulated platelets from peripheral blood. Platelets. 2021;32:113-119. Pubmed
  5. Bosmans LA, Bosch L, Kusters PJH, Lutgens E, Seijkens TTP. The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease. J Cardiovasc Transl Res. 2021;14:13-22. Pubmed
  6. Bosmans LA, Shami A, Atzler D, Weber C, Goncalves I, Lutgens E. Glucocorticoid induced TNF receptor family-related protein (GITR) - A novel driver of atherosclerosis. Vascul Pharmacol. 2021;139:106884. Pubmed
  7. Chirivi RGS, van Rosmalen JWG, van der Linden M, Euler M, Schmets G, Bogatkevich G, Kambas K, Hahn J, Braster Q, Soehnlein O, Hoffmann MH, Es H, Raats JMH. Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases. Cell Mol Immunol. 2021;18:1528-1544. Pubmed
  8. Chondronikola M, Bartelt A, Vidal-Puig A, Virtanen KA. Editorial: Brown Adipose Tissue: From Heat Production in Rodents to Metabolic Health in Humans. Front Endocrinol (Lausanne). 2021;12:739065. Pubmed
  9. Datta-Chaudhuri T, Zanos T, Chang EH, Olofsson PS, Bickel S, Bouton C, Grande D, Rieth L, Aranow C, Bloom O, Mehta AD, Civillico G, Stevens MM, Glowacki E, Bettinger C, Schuettler M, Puleo C, Rennaker R, Mohanta S, Carnevale D, Conde SV, Bonaz B, Chernoff D, Kapa S, Berggren M, Ludwig K, Zanos S, Miller L, Weber D, Yoshor D, Steinman L, Chavan SS, Pavlov VA, Al-Abed Y, Tracey KJ. The Fourth Bioelectronic Medicine Summit "Technology Targeting Molecular Mechanisms": current progress, challenges, and charting the future. Bioelectron Med. 2021;7:7. Pubmed
  10. Davidson SM, Padro T, Bollini S, Vilahur G, Duncker DJ, Evans PC, Guzik T, Hoefer IE, Waltenberger J, Wojta J, Weber C. Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart. Cardiovasc Res. 2021;117:2161-2174. Pubmed
  11. Dickhout A, Kaczor DM, Heinzmann ACA, Brouns SLN, Heemskerk JWM, van Zandvoort M, Koenen RR. Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells. Int J Mol Sci. 2021;22. Pubmed
  12. Dickhout A, Tullemans BME, Heemskerk JWM, Thijssen V, Kuijpers MJE, Koenen RR. Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro. PLoS One. 2021;16:e0244736. Pubmed
  13. Duan R, Goldmann L, Brandl R, Spannagl M, Weber C, Siess W, von Hundelshausen P. Effects of the Btk-Inhibitors Remibrutinib (LOU064) and Rilzabrutinib (PRN1008) With Varying Btk Selectivity Over Tec on Platelet Aggregation and in vitro Bleeding Time. Front Cardiovasc Med. 2021;8:749022. Pubmed
  14. Duan R, Goldmann L, Li Y, Weber C, Siess W, von Hundelshausen P. Spontaneous Platelet Aggregation in Blood Is Mediated by FcgammaRIIA Stimulation of Bruton's Tyrosine Kinase. Int J Mol Sci. 2021;23. Pubmed

  15. Egea V, Kessenbrock K, Lawson D, Bartelt A, Weber C, Ries C. Let-7f miRNA regulates SDF-1alpha- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release. Cell Death Dis. 2021;12:516. Pubmed
  16. Evans P, Wojta J, Hoefer IE, Waltenberger J, Guzik T, Badimon L, Weber C. The year in basic vascular biology research: from mechanoreceptors and neutrophil extracellular traps to smartphone data and omics. Cardiovasc Res. 2021;117:1814-1822. Pubmed
  17. Fasolo F, Jin H, Winski G, Chernogubova E, Pauli J, Winter H, Li DY, Glukha N, Bauer S, Metschl S, Wu Z, Koschinsky ML, Reilly M, Pelisek J, Kempf W, Eckstein HH, Soehnlein O, Matic L, Hedin U, Backlund A, Bergmark C, Paloschi V, Maegdefessel L. Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization. Circulation. 2021;144:1567-1583. Pubmed
  18. Fidler TP, Xue C, Yalcinkaya M, Hardaway B, Abramowicz S, Xiao T, Liu W, Thomas DG, Hajebrahimi MA, Pircher J, Silvestre-Roig C, Kotini AG, Luchsinger LL, Wei Y, Westerterp M, Snoeck HW, Papapetrou EP, Schulz C, Massberg S, Soehnlein O, Ebert B, Levine RL, Reilly MP, Libby P, Wang N, Tall AR. The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis. Nature. 2021;592:296-301. Pubmed
  19. Gencer S, Doring Y, Jansen Y, Bayasgalan S, Schengel O, Muller M, Peters LJF, Weber C, van der Vorst EPC. Adipocyte-Specific ACKR3 Regulates Lipid Levels in Adipose Tissue. Biomedicines. 2021;9:11. Pubmed
  20. Gencer S, Evans BR, van der Vorst EPC, Doring Y, Weber C. Inflammatory Chemokines in Atherosclerosis. Cells. 2021;10. Pubmed
  21. Georgakis MK, van der Laan SW, Asare Y, Mekke JM, Haitjema S, Schoneveld AH, de Jager SCA, Nurmohamed NS, Kroon J, Stroes ESG, de Kleijn DPV, de Borst GJ, Maegdefessel L, Soehnlein O, Pasterkamp G, Dichgans M. Monocyte-Chemoattractant Protein-1 Levels in Human Atherosclerotic Lesions Associate With Plaque Vulnerability. Arterioscler Thromb Vasc Biol. 2021;41:2038-2048. Pubmed
  22. Ghiboub M, Elfiky AMI, de Winther MPJ, Harker NR, Tough DF, de Jonge WJ. Selective Targeting of Epigenetic Readers and Histone Deacetylases in Autoimmune and Inflammatory Diseases: Recent Advances and Future Perspectives. J Pers Med. 2021;11. Pubmed
  23. Giroud M, Tsokanos FF, Caratti G, Kotschi S, Khani S, Jouffe C, Vogl ES, Irmler M, Glantschnig C, Gil-Lozano M, Hass D, Khan AA, Garcia MR, Mattijssen F, Maida A, Tews D, Fischer-Posovszky P, Feuchtinger A, Virtanen KA, Beckers J, Wabitsch M, Uhlenhaut H, Bluher M, Tuckermann J, Scheideler M, Bartelt A, Herzig S. HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling. Diabetologia. 2021;64:1850-1865. Pubmed
  24. Gissler MC, Scherrer P, Anto-Michel N, Pennig J, Hoppe N, Funer L, Hardtner C, Stachon P, Li X, Mitre LS, Marchini T, Madl J, Wadle C, Hilgendorf I, von Zur Muhlen C, Bode C, Weber C, Lutgens E, Wolf D, Gerdes N, Zirlik A, Willecke F. Deficiency of Endothelial CD40 Induces a Stable Plaque Phenotype and Limits Inflammatory Cell Recruitment to Atherosclerotic Lesions in Mice. Thromb Haemost. 2021;121:1530-1540. Pubmed
  25. Goncalves RLS, Schlame M, Bartelt A, Brand MD, Hotamisligil GS. Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H2 O2 production in heart and skeletal muscle mitochondria. FEBS Lett. 2021;595:415-432. Pubmed
  26. Gutjahr JC, Crawford KS, Jensen DR, Naik P, Peterson FC, Samson GPB, Legler DF, Duchene J, Veldkamp CT, Rot A, Volkman BF. The dimeric form of CXCL12 binds to atypical chemokine receptor 1. Sci Signal. 2021;14. Pubmed
  27. Hall IF, Climent M, Viviani Anselmi C, Papa L, Tragante V, Lambroia L, Farina FM, Kleber ME, Marz W, Biguori C, Condorelli G, Elia L. rs41291957 controls miR-143 and miR-145 expression and impacts coronary artery disease risk. EMBO Mol Med. 2021;13:e14060. Pubmed
  28. He YY, Xie XM, Zhang HD, Ye J, Gencer S, van der Vorst EPC, Doring Y, Weber C, Pang XB, Jing ZC, Yan Y, Han ZY. Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. Front Pharmacol. 2021;12:753727. Pubmed
  29. Henderson JM, Weber C, Santovito D. Beyond Self-Recycling: Cell-Specific Role of Autophagy in Atherosclerosis. Cells. 2021;10. Pubmed
  30. Hinkel R, Batkai S, Bahr A, Bozoglu T, Straub S, Borchert T, Viereck J, Howe A, Hornaschewitz N, Oberberger L, Jurisch V, Kozlik-Feldmann R, Freudenthal F, Ziegler T, Weber C, Sperandio M, Engelhardt S, Laugwitz KL, Moretti A, Klymiuk N, Thum T, Kupatt C. AntimiR-132 Attenuates Myocardial Hypertrophy in an Animal Model of Percutaneous Aortic Constriction. J Am Coll Cardiol. 2021;77:2923-2935. Pubmed
  31. Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek AL, Zimmermann AS, Wobst J, Muller P, Mauersberger C, Vilne B, Baecklund A, Chen CS, Moggio A, Braster Q, Molitor M, Krane M, Kempf WE, Ladwig KH, Hristov M, Hulsmans M, Hilgendorf I, Weber C, Wenzel P, Scheiermann C, Maegdefessel L, Soehnlein O, Libby P, Nahrendorf M, Schunkert H, Kessler T, Sager HB. Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis. Eur Heart J. 2021;42:4077-4088. Pubmed
  32. Kassiteridi C, Cole JE, Griseri T, Falck-Hansen M, Goddard ME, Seneviratne AN, Green PA, Park I, Shami AG, Pattarabanjird T, Upadhye A, Taylor AM, Handa A, Channon KM, Lutgens E, McNamara CA, Williams RO, Monaco C. CD200 Limits Monopoiesis and Monocyte Recruitment in Atherosclerosis. Circ Res. 2021;129:280-295. Pubmed
  33. Kluza E, Beldman TJ, Shami A, Scholl ER, Malinova TS, Grootemaat AE, van der Wel NN, Goncalves I, Huveneers S, Mulder WJM, Lutgens E. Diverse ultrastructural landscape of atherosclerotic endothelium. Atherosclerosis. 2021;339:35-45. Pubmed
  34. Koenen RR. Conformation-Crooking CXCL4 to Unravel Autoimmune Heparin-Induced Thrombocytopenia. Thromb Haemost. 2021;121:258-260. Pubmed
  35. Kou J, Wang M, Shi J, Zhang H, Pu X, Song S, Yang C, Yan Y, Doring Y, Xie X, Pang X. Curcumin Reduces Cognitive Deficits by Inhibiting Neuroinflammation through the Endoplasmic Reticulum Stress Pathway in Apolipoprotein E4 Transgenic Mice. ACS Omega. 2021;6:6654-6662. Pubmed
  36. Krammer C, Kontos C, Dewor M, Hille K, Dalla Volta B, El Bounkari O, Tas K, Sinitski D, Brandhofer M, Megens RTA, Weber C, Schultz JR, Bernhagen J, Kapurniotu A. A MIF-Derived Cyclopeptide that Inhibits MIF Binding and Atherogenic Signaling via the Chemokine Receptor CXCR2. Chembiochem. 2021;22:1012-1019. Pubmed
  37. Lacy M, Burger C, Shami A, Ahmadsei M, Winkels H, Nitz K, van Tiel CM, Seijkens TTP, Kusters PJH, Karshovka E, Prange KHM, Wu Y, Brouns SLN, Unterlugauer S, Kuijpers MJE, Reiche ME, Steffens S, Edsfeldt A, Megens RTA, Heemskerk JWM, Goncalves I, Weber C, Gerdes N, Atzler D, Lutgens E. Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease. Nat Commun. 2021;12:3754. Pubmed
  38. Lee MW, Luo EW, Silvestre-Roig C, Srinivasan Y, Akabori K, Lemnitzer P, Schmidt NW, Lai GH, Santangelo CD, Soehnlein O, Wong GCL. Apolipoprotein Mimetic Peptide Inhibits Neutrophil-Driven Inflammatory Damage via Membrane Remodeling and Suppression of Cell Lysis. ACS Nano. 2021;15:15930-15939. Pubmed
  39. Lemmer IL, Willemsen N, Hilal N, Bartelt A. A guide to understanding endoplasmic reticulum stress in metabolic disorders. Mol Metab. 2021;47:101169. Pubmed
  40. Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha BL, Dantes Z, Rataj F, Dorman K, Lutz J, Karches CH, Heise C, Kurzay M, Larimer BM, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth C, Benmebarek MR, Dhoqina D, Grunmeier R, Seifert M, Oener A, Umut O, Joaquina S, Vimeux L, Tran T, Hank T, Baba T, Huynh D, Megens RTA, Janssen KP, Jastroch M, Lamp D, Ruehland S, Di Pilato M, Pruessmann JN, Thomas M, Marr C, Ormanns S, Reischer A, Hristov M, Tartour E, Donnadieu E, Rothenfusser S, Duewell P, Konig LM, Schnurr M, Subklewe M, Liss AS, Halama N, Reichert M, Mempel TR, Endres S, Kobold S. T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. Nat Biomed Eng. 2021;5:1246-1260. Pubmed
  41. Lip GYH, Rigby A, Weber C. Looking Back on 2020, Looking Forward to 2021. Thromb Haemost. 2021;121:1-3. Pubmed
  42. Lutgens E, Joffre J, van Os B, Ait-Oufella H. Targeting cytokines and immune checkpoints in atherosclerosis with monoclonal antibodies. Atherosclerosis. 2021;335:98-109. Pubmed
  43. Maciuszek M, Ortega-Gomez A, Maas SL, Garrido-Mesa J, Ferraro B, Perretti M, Merritt A, Nicolaes GAF, Soehnlein O, Chapman TM. Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists. Eur J Med Chem. 2021;226:113805. Pubmed
  44. Maciuszek M, Ortega-Gomez A, Maas SL, Perretti M, Merritt A, Soehnlein O, Chapman TM. Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation. Eur J Med Chem. 2021;214:113194. Pubmed
  45. Marquez AB, van der Vorst EPC, Maas SL. Key Chemokine Pathways in Atherosclerosis and Their Therapeutic Potential. J Clin Med. 2021;10. Pubmed
  46. Muley C, Bartelt A. Fuse your mitochondria, lose appetite: an anorexic, anti-obesity sphingolipid. EMBO Mol Med. 2021;13:e14618. Pubmed
  47. Muley C, Kotschi S, Bartelt A. Role of Ubiquilins for Brown Adipocyte Proteostasis and Thermogenesis. Front Endocrinol (Lausanne). 2021;12:739021. Pubmed
  48. Natarelli L, Parca L, Mazza T, Weber C, Virgili F, Fratantonio D. MicroRNAs and Long Non-Coding RNAs as Potential Candidates to Target Specific Motifs of SARS-CoV-2. Noncoding RNA. 2021;7. Pubmed
  49. Natarelli L, Virgili F, Weber C. SARS-CoV-2, Cardiovascular Diseases, and Noncoding RNAs: A Connected Triad. Int J Mol Sci. 2021;22. Pubmed
  50. Neele AE, Chen HJ, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Van den Bossche J, Tool AT, Matlung HL, van den Berg TK, Lutgens E, de Winther MPJ. Myeloid Ezh2 Deficiency Limits Atherosclerosis Development. Front Immunol. 2020;11:594603. Pubmed
  51. Nording H, Baron L, Haberthur D, Emschermann F, Mezger M, Sauter M, Sauter R, Patzelt J, Knoepp K, Nording A, Meusel M, Meyer-Saraei R, Hlushchuk R, Sedding D, Borst O, Eitel I, Karsten CM, Feil R, Pichler B, Erdmann J, Verschoor A, Chavakis E, Chavakis T, von Hundelshausen P, Kohl J, Gawaz M, Langer HF. The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets. Nat Commun. 2021;12:3352. Pubmed
  52. Perrino C, Ferdinandy P, Botker HE, Brundel B, Collins P, Davidson SM, den Ruijter HM, Engel FB, Gerdts E, Girao H, Gyongyosi M, Hausenloy DJ, Lecour S, Madonna R, Marber M, Murphy E, Pesce M, Regitz-Zagrosek V, Sluijter JPG, Steffens S, Gollmann-Tepekoylu C, Van Laake LW, Van Linthout S, Schulz R, Ytrehus K. Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart. Cardiovasc Res. 2021;117:367-385. Pubmed
  53. Pesce M, Agostoni P, Botker HE, Brundel B, Davidson SM, Caterina R, Ferdinandy P, Girao H, Gyongyosi M, Hulot JS, Lecour S, Perrino C, Schulz R, Sluijter JP, Steffens S, Tancevski I, Gollmann-Tepekoylu C, Tschope C, Linthout SV, Madonna R. COVID-19-related cardiac complications from clinical evidences to basic mechanisms: opinion paper of the ESC Working Group on Cellular Biology of the Heart. Cardiovasc Res. 2021;117:2148-2160. Pubmed
  54. Peters LJF, Jans A, Bartneck M, van der Vorst EPC. Immunomodulatory Nanomedicine for the Treatment of Atherosclerosis. J Clin Med. 2021;10. Pubmed
  55. Poels K, Neppelenbroek SIM, Kersten MJ, Antoni ML, Lutgens E, Seijkens TTP. Immune checkpoint inhibitor treatment and atherosclerotic cardiovascular disease: an emerging clinical problem. J Immunother Cancer. 2021;9. Pubmed
  56. Puhl SL, Hilby M, Kohlhaas M, Keidel LM, Jansen Y, Hristov M, Schindler J, Maack C, Steffens S. Haematopoietic and cardiac GPR55 synchronize post-myocardial infarction remodelling. Sci Rep. 2021;11:14385. Pubmed
  57. Reiche ME, Lutgens E. Lose the helpers... get 'remote' regulators! Cardiovasc Res. 2021;117:635-636. Pubmed
  58. Reilly NA, Lutgens E, Kuiper J, Heijmans BT, Wouter Jukema J. Effects of fatty acids on T cell function: role in atherosclerosis. Nat Rev Cardiol. 2021;18:824-837. Pubmed
  59. Rossaint J, Thomas K, Mersmann S, Skupski J, Margraf A, Tekath T, Jouvene CC, Dalli J, Hidalgo A, Meuth SG, Soehnlein O, Zarbock A. Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education. J Exp Med. 2021;218. Pubmed
  60. Saar-Kovrov V, Donners M, van der Vorst EPC. Shedding of Klotho: Functional Implications in Chronic Kidney Disease and Associated Vascular Disease. Front Cardiovasc Med. 2020;7:617842. Pubmed
  61. Santovito D, Steffens S. DNA damage and extranuclear DNA sensors: a dangerous duo in atherosclerosis. Eur Heart J. 2021;42:4349-4351. Pubmed
  62. Santovito D, Toto L, De Nardis V, Marcantonio P, D'Aloisio R, Mastropasqua A, De Cesare D, Bucci M, Paganelli C, Natarelli L, Weber C, Consoli A, Mastropasqua R, Cipollone F. Plasma microRNA signature associated with retinopathy in patients with type 2 diabetes. Sci Rep. 2021;11:4136. Pubmed

  63. Santovito D, Weber C. Not all myocardial infarctions are created equal: The potential of circulating microRNAs to discern coronary artery dissection. EBioMedicine. 2021;67:103366. Pubmed
  64. Schindler L, Zwissler L, Krammer C, Hendgen-Cotta U, Rassaf T, Hampton MB, Dickerhof N, Bernhagen J. Macrophage migration inhibitory factor inhibits neutrophil apoptosis by inducing cytokine release from mononuclear cells. J Leukoc Biol. 2021;110:893-905. Pubmed
  65. Schlein C, Fischer AW, Sass F, Worthmann A, Todter K, Jaeckstein MY, Behrens J, Lynes MD, Kiebish MA, Narain NR, Bussberg V, Darkwah A, Jespersen NZ, Nielsen S, Scheele C, Schweizer M, Braren I, Bartelt A, Tseng YH, Heeren J, Scheja L. Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution. Cell Rep. 2021;34:108624. Pubmed
  66. Schmohl J, Moebius S, Guenther T, Pepeldjyika E, Seidel CL, Sutanto W, Schuster F, Kraemer D, Salih H, Hartmann A, Tischer J, Ries C, Schmetzer H. Expression of Surface-associated 82 kDa proMMP-9 in Lymphatic Leukemia Blast Cells Differentially Correlates With Prognosis. Anticancer Res. 2021;41:3891-3898. Pubmed
  67. Schober A, Blay RM, Saboor Maleki S, Zahedi F, Winklmaier AE, Kakar MY, Baatsch IM, Zhu M, Geissler C, Fusco AE, Eberlein A, Li N, Megens RTA, Banafsche R, Kumbrink J, Weber C, Nazari-Jahantigh M. MicroRNA-21 Controls Circadian Regulation of Apoptosis in Atherosclerotic Lesions. Circulation. 2021;144:1059-1073. Pubmed
  68. Schoeps B, Eckfeld C, Prokopchuk O, Bottcher J, Haussler D, Steiger K, Demir IE, Knolle P, Soehnlein O, Jenne DE, Hermann CD, Kruger A. TIMP1 Triggers Neutrophil Extracellular Trap Formation in Pancreatic Cancer. Cancer Res. 2021;81:3568-3579. Pubmed
  69. Schumacher D, Curaj A, Simsekyilmaz S, Schober A, Liehn EA, Mause SF. miR155 Deficiency Reduces Myofibroblast Density but Fails to Improve Cardiac Function after Myocardial Infarction in Dyslipidemic Mouse Model. Int J Mol Sci. 2021;22. Pubmed
  70. Schumacher D, Liehn EA, Singh A, Curaj A, Wijnands E, Lira SA, Tacke F, Jankowski J, Biessen EAL, van der Vorst EPC. CCR6 Deficiency Increases Infarct Size after Murine Acute Myocardial Infarction. Biomedicines. 2021;9. Pubmed
  71. Schumski A, Ortega-Gomez A, Wichapong K, Winter C, Lemnitzer P, Viola JR, Pinilla-Vera M, Folco E, Solis-Mezarino V, Volker-Albert M, Maas SL, Pan C, Perez Olivares L, Winter J, Hackeng T, Karlsson MCI, Zeller T, Imhof A, Baron RM, Nicolaes GAF, Libby P, Maegdefessel L, Kamp F, Benoit M, Doring Y, Soehnlein O. Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge-Mediated Monocyte Adhesion. Circulation. 2021;143:254-266. Pubmed
  72. Sebag SC, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, Li W, Zingman LV, Liu L, Lira VA, Potthoff MJ, Bartelt A, Yang L. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell Rep. 2021;37:110003. Pubmed
  73. Shami A, Edsfeldt A, Bengtsson E, Nilsson J, Shore AC, Natali A, Khan F, Lutgens E, Goncalves I. Soluble CD40 Levels in Plasma Are Associated with Cardiovascular Disease and in Carotid Plaques with a Vulnerable Phenotype. J Stroke. 2021;23:367-376. Pubmed
  74. Silvestre-Roig C, Lemnitzer P, Gall J, Schwager S, Toska A, Yvan-Charvet L, Detmar M, Soehnlein O. Arterial Delivery of VEGF-C Stabilizes Atherosclerotic Lesions. Circ Res. 2021;128:284-286. Pubmed
  75. Soehnlein O, Libby P. Targeting inflammation in atherosclerosis - from experimental insights to the clinic. Nat Rev Drug Discov. 2021;20:589-610. Pubmed
  76. Soltani-Fard E, Taghvimi S, Abedi Kichi Z, Weber C, Shabaninejad Z, Taheri-Anganeh M, Hossein Khatami S, Mousavi P, Movahedpour A, Natarelli L. Insights into the Function of Regulatory RNAs in Bacteria and Archaea. International Journal of Translational Medicine 2021; 1(3): 403-423. https://www.mdpi.com/2673-8937/1/3/24
  77. Sundararaman SS, Doring Y, van der Vorst EPC. PCSK9: A Multi-Faceted Protein That Is Involved in Cardiovascular Biology. Biomedicines. 2021;9. Pubmed
  78. Sundararaman SS, Peters LJF, Jansen Y, Gencer S, Yan Y, Nazir S, Bonnin Marquez A, Kahles F, Lehrke M, Biessen EAL, Jankowski J, Weber C, Doring Y, van der Vorst EPC. Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe(-/-) mice. Sci Rep. 2021;11:10409. Pubmed
  79. Sundararaman SS, Peters LJF, Nazir S, Marquez AB, Bouma JE, Bayasgalan S, Doring Y, van der Vorst EPC. PCSK9 Imperceptibly Affects Chemokine Receptor Expression In Vitro and In Vivo. Int J Mol Sci. 2021;22. Pubmed
  80. Sundararaman SS, van der Vorst EPC. Calcium-Sensing Receptor (CaSR), Its Impact on Inflammation and the Consequences on Cardiovascular Health. Int J Mol Sci. 2021;22. Pubmed
  81. Tahir S, Steffens S. Nonclassical monocytes in cardiovascular physiology and disease. Am J Physiol Cell Physiol. 2021;320:C761-C770. Pubmed
  82. Thakur M, Evans B, Schindewolf M, Baumgartner I, Doring Y. Neutrophil Extracellular Traps Affecting Cardiovascular Health in Infectious and Inflammatory Diseases. Cells. 2021;10. Pubmed
  83. Totzeck M, Lutgens E, Neilan TG. Are we underestimating the potential for cardiotoxicity related to immune checkpoint inhibitors? Eur Heart J. 2021;42:1632-1635. Pubmed
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  85. Tullemans BME, Karel MFA, Leopold V, Ten Brink MS, Baaten C, Maas SL, de Vos AF, Eble JA, Nijziel MR, van der Vorst EPC, Cosemans J, Heemskerk JWM, Claushuis TAM, Kuijpers MJE. Comparison of inhibitory effects of irreversible and reversible Btk inhibitors on platelet function. EJHaem. 2021;2:685-699. Pubmed

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