Publications (selected)

2020

• Denner J, Längin M, Reichart B, Krüger L, Fiebig U, Mokelke M, Radan J, Mayr T, Milusev A, Luther F, Sorvillo N, Rieben R, Brenner P, Walz C, Wolf E, Roshani B, Stahl‑Hennig C, Abicht JM. Impact of porcine cytomegalovirus on long-term orthotopic cardiac xenotransplant survival. Sci Rep Oct 16;10(1):17531. doi: 10.1038/s41598-020-73150-9.

• Reichart B, Längin M, Radan J, Mokelke M, Buttgereit I, Ying J, Fresch AK, Mayr T, Issl L, Buchholz S, Michel S, Ellgass R, Mihalj M, Egerer S, Baehr A, Kessler B, Kemter E, Kurome M, Zakhartchenko V, Steen S, Sjöberg T, Paskevicius A, Krüger L, Fiebig U, Denner J, Godehardt AW, Tönjes RR, Milusev A, Rieben R, Sfriso R, Walz C, Kirchner T, Ayares D, Lampe K, Schönmann U, Hagl C, Wolf E, Klymiuk N, Abicht JM, Brenner P. Pig-to-non-human primate heart transplantation: The final step toward clinical xenotransplantation? J Heart Lung Transplant. Aug;39(8):751-757.

2018

• Längin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, Buttgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjöberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schönmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht J. Consistent success in life-supporting porcine cardiac xenotransplantation. Nature 5. Dez.;564, pages430–433
  
  
• Längin M, Panelli A, Reichart B, Kind A, Brenner P, Mayr T, Abicht JM. Perioperative Telemetric Monitoring in Pig-to-Baboon Heterotopic Thoracic Cardiac Xenotransplantation. Ann Transplant. Jul 20;23:491-499. doi: 10.12659/AOT.909522.

2017

• Mayr T, Bauer A, Reichart B, Guethoff S, Schoenmann U, Längin M, Panelli A, Kind A, Brenner P, Abicht JM. Hemodynamic and perioperative management in two different preclinical pig-to-baboon cardiac xenotransplantation models. Xenotransplantation. May;24(3). doi: 10.1111/xen.12295. Epub 2017 Mar 5.

2015

• Abicht, J, Mayr T, Reichart B, Buchholz S, Werner F, Lutzmann I, Schmoeckel M, Bauer A, Thormann M, Langenmayer MC, Herbach N, Pohla H, Herzog R, McGregor CGA, Ayares D, Wolf E, Klymiuk N, Baehr A, Kind A, Hagl C, Ganswindt U, Belka C, Guethoff S, Brenner P. Preclinical heterotopic intrathoracic heart Xenotransplantation: a possibly useful clinical technique. Xenotransplantation (in press).
  
  
• Geiger, D, Buchholz S, Michel S, Abicht J, Reichel CA, Reichart B, Hagl C, Brenner P and Schramm, R. The Coronary Microcirculation in Hamster-to-Rat Cardiac Xenografts. European surgical research 55, 364-373.
  
  
• Reichart, B, Guethoff S, Brenner P, Poettinger T, Wolf E, Ludwig B, Kind A, Mayr T and Abicht JM. Xenotransplantation of Cells, Tissues, Organs and the German Research Foundation Transregio Collaborative Research Centre 127. In: Immune Responses to Biosurfaces. Advances in experimental medicine and biology 865, 143-155.
  
  
• Reichart, B, Guethoff S, Mayr T, Thormann M, Buchholz S, Abicht J, Kind A, Brenner P. Discordant Cellular and Organ Xenotransplantation – from Bench to Bedside. In: Organ Transplantation in Times of Donor Shortage: Challenges and Solutions. International Library of Ethics, Law, and the New Medicine 59, 209-220.

2014

• Reichart, B, Guethoff S, Mayr T, Thormann M, Buchholz S, Postrach J, Ayares D, Elliott RB, Tan P, Kind A, Hagl C, Brenner P, Abicht JM. Discordant cardiac xenotransplantation: broadening the horizons. European journal of cardio-thoracic surgery  45, 1-5.

2012

• Mair H, Sachweh J, Sodian R, Brenner P, Schmoeckel M, Schmitz C, Reichart B, Daebritz S. Long-term self-management of anticoagulation therapy after mechanical heart valve replacement in outside trial conditions. Interac Cardiovasc Thorac Surg:14(3):253-257.

2011

• Beiras-Fernandez A, Deutsch MA, Kainzinger S, Kaczmarek I, Sodian R, Überfuhr P, Meiser B, Schmoeckel M, Reichart B, Brenner P. Extracorporeal membrane oxygenation in 108 patients with low cardiac output – a single center experience. Int J Artif Organs:34(4):365-373.
  
  
• Bauer A, Renz V, Baschnegger H, Abicht J-M, Beiras-Fernandez A, Brenner P, Thein E, Schmoeckel M, Reichart B, Christ F. Microcirculatory alterations after orthotopic pig-to-baboon heart transplantation. Xenotransplantation; 18: 232–238.

2010

• Bauer A, Postrach J, Thormann M, Blanck S, Faber C, Wintersperger B, Michel S, Abicht JM, Christ F, Schmitz C, Schmoeckel M, Reichart B, Brenner P. First experience with heterotopic thoracic pig-to-baboon cardiac xenotransplantation. Xenotransplantation;17(3):243-249.
  
  
• Keller M, Beiras-Fernandez A, Schmoeckel M, Reichart B, Brenner P. Influence of hypothermia and cardioplegic solutions upon the expression of the α-Gal epitope on porcine aortic endothelial cells. Exp Clin Transplant.;8(3):250-257.

• Brenner P, Keller M, Beiras-Fernandez A, Uchita S, Kur F, Thein E, Huber H, Wimmer C, Hammer C, Schmoeckel M, Reichart B. Prevention of Hyperacute Xenograft Rejection through direct Thrombin inhibition with Hirudin. Ann Transplant:15(4):30-37.

2009

• Zimmermann G, Reithmann C, Strauss T, Hatz R, Brenner P, Überfuhr A, Frey L, Nikolaou K, Behr J. Successful angioplasty and stent treatment of pulmonary vein stenosis after single-lung transplantation. J Heart Lung Transplant;28(2):194-198.

2007

• Brandl U, Jöckle H, Erhardt M, Michel S, Burdorf L, Brenner P, Bittmann I, Rössle M, Mordstein V, Hammer C, Thein E, Reichart B, Schmoeckel M. Reduced fibrin deposition and intravascular thrombosis in hDAF transgenic pig hearts perfused with tirofiban. Transplantation;27:84(12):1667-1676.
  
  
• Brandl U, Erhardt M, Michel S, Jöckle H, Burdorf L, Bittmann I, Rössle M, Mordstein V, Brenner P, Hammer C, Reichart B, Schmoeckel M. Soluble Galalpha(1,3)Gal conjugate combined with hDAF preserves morphology and improves function of cardiac xenografts. Xenotransplantation;14(4):323-332.
  
  
• Bigdeli AK, Beiras-Fernandez A, Kaczmarek I, Sadoni S, Brenner P, Schmoeckel M, Nikolaou K, Reichart B. Successful pulmonary thromboendarterectomy for right atrial thrombosis in a heart transplant recipient: a case report. Exp Clin Transplant;5(1):621-623.
  
  
• Bauer A, Baschnegger H, Renz V, Brandl U, Brenner P, Thein E, Reichart B, Schmoeckel M, Christ F. Comparison of propofol and isoflurane anesthesia in orthotopic pig-to-baboon cardiac xenotransplantation. Xenotransplantation;14(3):249-254.
  
  
• Kaczmarek I, Deutsch MA, Sadoni S, Brenner P, Schmauss D, Daebritz SH, Weiss M, Meiser BM, Reichart B. Successful management of antibody-mediated cardiac allograft rejection with combined immunoadsorption and anti-CD20 monoclonal antibody treatment: case report and literature review. J Heart Lung Transplant;26(5):511-515.
  
  
• Brandl U, Michel S, Erhardt M, Brenner P, Burdorf L, Jöckle H, Bittmann I, Rössle M, Mordstein V, Baschnegger H, Bauer A, Hammer C, Reichart B, Schmoeckel M. Transgenic animals in experimental xenotransplantation models: orthotopic heart transplantation in the pig-to-baboon model. Transplant Proc;39(2):577-578.

2006

• Brandl U, Erhardt M, Jöckle H, Michel S, Thein E, Bittmann I, Brenner P, Burdorf L, Hammer C, Schmoeckel M, Reichart B. Fluorescent microspheres reveal different regional blood flow in hyperacutely rejected nontransgenic and hDAF pig hearts. Transplant Proc;38(3):733-734.

2005

• Brenner P, Schmoeckel M, Wimmer C, Rucker A, Eder V, Uchita S, Brandl U, Hinz M, Felbinger T, Meiser B, Hammer C, Reichenspurner H, Reichart B. Combination of hDAF-transgenic pig hearts and immunoadsorption in heterotopic xenotransplantation of immunosuppressed baboons. Transplant Proc.; 37(1):483-486.
  
  
• Brenner P, Schmoeckel M, Wimmer C, Eder V, Rucker A, Felbinger T, Uchita S, Hinz M, Brandl U, Meiser B, Reichenspurner H, Hammer C, Reichart B. Mean xenograft survival of 14.6 days in a small group of hDAF transgenic pig hearts transplanted orthotopically into baboons. Transplant Proc.; 37(1):472-476.
  
  
• Brenner P. Antriebstechniken von Kunstherzen. Technik in Bayern;5:16-17.

• Brandl U, Michel S, Erhardt M, Brenner P, Bittmann I, Rössle M, Baschnegger H, Bauer A, Hammer C, Schmoeckel M, Reichart B. Administration of GAS914 in an orthotopic pig-to-baboon heart transplantation model. Xenotransplantation;12(2):134-141.
  
  
• Bauer A, Baschnegger H, Abicht JM, Brandl U, Brenner P, Thein E, Hammer C, Reichart B, Peter K, Schmoeckel M, Christ F. hDAF porcine cardiac xenograft maintains cardiac output after orthotopic transplantation into baboon - a perioperative study. Xenotransplantation;12(6):444-449.
  
  
• Brandl U, Erhardt M, Joeckle H, Michel S, Brenner P, Bittmann I, Roessle M, Mordstein V, Hammer C, Schmoeckel M, Reichart B. Combining the hDAF transgene with the GP IIb/IIIa inhibitor tirofiban improves heart performance and reduces myocardial damage following hyperacute rejection in an ex vivo perfusion model. Transplant Proc;37(1):491-492.
  
  

2001

• Wildhirt SM, Schulze C, Schulz C, Egi K, Brenner P, Mair H, Schütz A, Reichart B. Reduction of systemic and cardiac adhesion molecule expression after off-pump versus conventional coronary artery bypass grafting. Shock; 16(1):55-59. 
  
  
• Uchita S, Thein E, Huber H, Wimmer C, Kur F, Brenner P, Hammer C. Porcine heart xenograft function and hyperacute rejection: the role of thrombin inhibition. Transplant Proc;33:729-731.
  
  

2000

• Brenner P, Reichenspurner H, Schmoeckel M, Wimmer C, Rucker A, Eder V, Meiser B, Hinz M, Felbinger T, Müller-Höcker J, Hammer C, Reichart B. IG-therasorb immunoapheresis in orthotopic xenotransplantation of baboons with landrace pig hearts. Transplantation;69(2):208-214.
  
  
• Brenner P, Hinz M, Huber H, Schmoeckel M, Reichenspurner H, Meiser B, Hammer C, Reichart B. Influence of ischemic time on hyperacute xenograft rejection of pig hearts in a working heart perfusion model with human blood. Transpl Int;13:494-503.
  
  
• Brenner P, Reichenspurner H, Schmoeckel M, Wimmer C, Rucker A, Eder V, Meiser B, Hinz M, Felbinger T, Hammer C, Reichart B. Prevention of hyperacute xenograft rejection in orthotopic xenotransplantation of pig hearts into baboons using immunoadsorption of antibodies and complement factors. Transpl Int;13(1):508-517.
  
  
• Brenner P, Schmoeckel M, Reichenspurner H, Felbinger T, Hinz M, Eder V, Rucker A, Wimmer C, Uchita S, Kriegeskorte S, Meiser B, Müller-Höcker J,  Seidel D, Hammer C, Reichart B. Technique of immunoapheresis in heterotopic and orthotopic xenotransplantation of pig hearts into cynomolgus and rhesus monkeys. Transplant Proc;32(5):1087-1088.

1999

• Brenner P, Hinz M, Huber H. Schmoeckel M, Reichenspurner H, Meiser B, Hammer C, Reichart B. Effects of prolonged cold storage time in xenotransplantation. J Heart Lung Transplant;18(12):1211-1217.
  
  
• Brenner P, M. Hinz, H. Huber, M. Schmoeckel, H. Reichenspurner, C.Hammer, B. Reichart. The influence of antibody and complement removal with a Ig-Therasorb column in a xenogeneic working heart model. Eur J Cardiothorac Surg;15(5):672-679.
  
  
• Brenner P, Schmoeckel M, Reichenspurner H, Rucker A, Wimmer C, Eder V, Hinz M, Hammer C, Reichart B. Technique of Ig-Therasorb immunoadsorption for prevention of hyperacute xenograft rejection in a baboon model with orthotopic xenotransplantation of the pig hearts. Langenbecks Arch Chir;1:977-980.
  
  
• Brenner P, Hinz M, Huber H. Schmoeckel M, Reichenspurner H, Meiser B, Müller-Höcker J, Seidel D, Hammer C, Reichart B. Säulenadsorption von Immunglobulinen und Komplementfaktoren verhindert die hyperakute, xenogene Abstoßungsreaktion im „working heart“-Perfusionsmodell von Schweineherzen. Transplantationsmedizin; 11:153-166.
  
  
• Brenner P, Wintersperger B, von Smekal A, Agirov V, Böhm D, Kreuzer E, Reiser M, Reichart B. Detection of coronary artery bypass graft patency by contrast enhanced magnetic resonance angiography. Eur J Cardiothorac Surg.;15(4):389-93.

1998

• Brenner P, Schmoeckel M, Huber H, Vetter HO, Müller-Höcker J, Hammer C, Reichart B. Influence of antibody removal by Ig-therasorb column immunoadsorption on hyperacute xenograft rejection in xenogenic perfusion model. Langenbecks Arch Chir;1:645-650.
  
  
• Brenner P, Wintersperger BJ, Agirov V, Kreuzer E, Reiser M, Reichart B. Control of the patency of coronary artery bypasses with contrast enhanced magnetic resonance angiography. Langenbecks Arch Chir; 115:1308-1311.

1995

• Brenner P, Meyer M, Reichenspurner H, Meiser B, Müller R, Mentz P, Schulz-Knappe P, Überbacher HJ, Kreuzer E, Überfuhr P, Guder WG, Wenzlaff H, Teschemacher H, Reichart B, Forssmann WG. Significance of prophylactic urodilatin (INN: ularitide) infusion for the prevention of acute renal failure in patients after heart transplantation. Eur J Med Res;1(3):137-143.
  
  
• Brenner P. Kooperation der Tierärztlichen Fakultät und der Fakultät Humanmedizin im High Tech Campus Martinsried-Großhadern im Bereich Xenotransplantation High Tech Campus Martinsried-Großhadern im Bereich Xenotransplantation

1999

• Boehm DH, Reichenspurner H, Gulbins H, Detter C, Meiser B, Brenner P, Habazettl H, Reichart B. Early experience with robotic technology for coronary artery surgery. Ann Thorac Surg; 68(4):1542-1546.

1997

• Gödje O, Brenner P, Smekal A, Fischlein T, Reichart B. 30 years survival after double valve replacement with Starr-Edwards prosthesis in aortic and mitral position. Eur J Cardiothorac Surg;11(2):391-393.

1996

• Seemann MD, Brenner P. Demonstration of spiral CT scans and reconstructions of a right atrial myxoma with bilateral pulmonary tumor emboli and a coincidental benign mediastinal thymoma. Eur J Med Res;1(11):515-519.
  
  
• Vetter HO, Brenner P, Dagge A, Erhorn A, Hammer C, Reichart B. Orthotopic transplantation of modified complete mitral valve homografts in sheep. Surgical technique. Eur J Card Intervent; 5(3):99-102. 

1995

• Vetter HO, Kaulbach HG, Schmitz C, Forst A, Überfuhr P, Kreuzer E, Pfeiffer M, Brenner P, Dewald O, Reichart B. Experience with the Novacor left ventricular assist system as a bridge to cardiac transplantation, including the new wearable system. J Thorac Cardiovasc Surg.; 109(1):74-80.

1992

• Dominiak P, Simon M, Blöchl A, Brenner P. Modulation of presynaptic sympathetic activity by kinins and related compounds: influence of converting enzyme inhibition. Agents Actions; 38(3):52-61.
  
  
• Dominiak P, Simon M, Blöchl A, Brenner P. Changes in peripheral sympathetic outflow of pithed spontaneously hypertensive rats after bradykinin and DesArg-bradykinin infusions: influence of converting-enzyme inhibition. J Cardiovasc Pharmacol; 20(9):35-38.

1991

• Dominiak P, Brenner P, Blöchl A, Simon M. Wirkung von Angiotensin I, Angiotensin II, und Bradykinin auf die Freisetzung endogener Katecholamine unter chronischer Hemmung des Konversionsenzyms. Focus MUL;4:210-217.