Publications (selected)
2021
- Böttcher et al., 2021: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates. Nature Cell Biology, DOI: 10.1038/s41556-020-00617-2
- Kemter E, Citro A, Wolf-van Buerck L, Qiu Y, Böttcher A, Policardi M, Pellegrini S, Valla L, Alunni-Fabbroni M, Kobolak J, Kessler B, Kurome M, Zakhartchenko V, Dinnyes A, Cyran C, Lickert H, Piemonti L, Seissler J, Wolf E. Transgenic pigs expressing near infrared fluorescent protein—A novel tool for noninvasive imaging of islet xenotransplants. Xenotransplantation, 21 December; doi.org/10.1111/xen.12719
2019
- Bakhti, M., Böttcher, A., and Lickert, H. Modelling the endocrine pancreas in health and disease. Nat Rev Endocrinol 15, 155-171.
- Wang, X., Sterr, M., Ansarullah, Burtscher, I., Böttcher, A., Beckenbauer, J., Siehler, J., Meitinger, T., Haring, H.U., Staiger, H., Cernilogar, F.M., Schotta, G., Irmler, M., Beckers, J., Wright, C.V.E., Bakhti, M., and Lickert, H. Point mutations in the PDX1 transactivation domain impair human beta-cell development and function. Mol Metab. 2019 Mar 20. pii: S2212-8778(19)30134-6. doi: 10.1016/j.molmet.2019.03.006.
2017
- Böttcher, A., Lickert, H., and Tschöp, M. Engineering Skin with Skinny Genes. Cell Stem Cell 21, 153-155.
- Tritschler, S., Theis, F.J., Lickert, H., and Böttcher, A. Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas. Mol Metab 6, 974-990.
2014
- Gegg, M., Böttcher, A., Burtscher, I., Hasenoeder, S., Van Campenhout, C., Aichler, M., Walch, A., Grant, S.G., and Lickert, H. Flattop regulates basal body docking and positioning in mono- and multiciliated cells. Elife 3.
2013
- Moik, D., Böttcher, A., Makhina, T., Grashoff, C., Bulus, N., Zent, R., and Fässler, R. Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice. J Biol Chem 288, 18863-18871.
2012
- Lange, A., Gegg, M., Burtscher, I., Bengel, D., Kremmer, E., and Lickert, H. Fltp(T2AiCre): a new knock-in mouse line for conditional gene targeting in distinct mono- and multiciliated tissues. Differentiation 83, S105-113.
2010
- Wickström, S.A., Lange, A., Hess, M.W., Polleux, J., Spatz, J.P., Kruger, M., Pfaller, K., Lambacher, A., Bloch, W., Mann, M. Huber, L.A., and Fässler, R. Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae. Dev Cell 19, 574-588.
- Wickström, S.A., Lange, A., Montanez, E., and Fässler, R. The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! EMBO J 29, 281-291.
2009
- Lange, A., Wickström, S.A., Jakobson, M., Zent, R., Sainio, K., and Fässler, R. Integrin-linked kinase is an adaptor with essential functions during mouse development. Nature 461, 1002-1006.
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1. Bakhti, M., Böttcher, A., and Lickert, H. (2019). Modelling the endocrine pancreas in health and disease. Nat Rev Endocrinol 15, 155-171. 2. Böttcher, A., Lickert, H., and Tschöp, M. (2017). Engineering Skin with Skinny Genes. Cell Stem Cell 21, 153-155. 3. Gegg, M., Böttcher, A., Burtscher, I., Hasenoeder, S., Van Campenhout, C., Aichler, M., Walch, A., Grant, S.G., and Lickert, H. (2014). Flattop regulates basal body docking and positioning in mono- and multiciliated cells. Elife 3. 4. Lange, A., Gegg, M., Burtscher, I., Bengel, D., Kremmer, E., and Lickert, H. (2012). Fltp(T2AiCre): a new knock-in mouse line for conditional gene targeting in distinct mono- and multiciliated tissues. Differentiation 83, S105-113. 5. Lange, A., Wickström, S.A., Jakobson, M., Zent, R., Sainio, K., and Fässler, R. (2009). Integrin-linked kinase is an adaptor with essential functions during mouse development. Nature 461, 1002-1006. 6. Moik, D., Böttcher, A., Makhina, T., Grashoff, C., Bulus, N., Zent, R., and Fässler, R. (2013). Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice. J Biol Chem 288, 18863-18871. 7. Tritschler, S., Theis, F.J., Lickert, H., and Böttcher, A. (2017). Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas. Mol Metab 6, 974-990. 8. Wang, X., Sterr, M., Ansarullah, Burtscher, I., Böttcher, A., Beckenbauer, J., Siehler, J., Meitinger, T., Haring, H.U., Staiger, H., Cernilogar, F.M., Schotta, G., Irmler, M., Beckers, J., Wright, C.V.E., Bakhti, M., and Lickert, H. (2019). Point mutations in the PDX1 transactivation domain impair human beta-cell development and function. Mol Metab. 2019 Mar 20. pii: S2212-8778(19)30134-6. doi: 10.1016/j.molmet.2019.03.006. 9. Wickström, S.A., Lange, A., Hess, M.W., Polleux, J., Spatz, J.P., Kruger, M., Pfaller, K., Lambacher, A., Bloch, W., Mann, M. Huber, L.A., and Fässler, R. (2010a). Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae. Dev Cell 19, 574-588. 10. Wickström, S.A., Lange, A., Montanez, E., and Fässler, R. (2010b). The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! EMBO J 29, 281-291. |
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