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Publications (selected)

2021

Zeitler L, Fiore A, Meyer C, Russier M, Zanella G, Suppmann S, Gargaro M, Sidhu S, Seshagiri S, Ohnmacht C, Köcher T, Fallarino F, Linkermann A, Murray PJ. Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism. Elife. Mar 1;10:e64806. doi: 10.7554/eLife.64806

Belavgeni, A. *, Bornstein, S.R.*, von Mässenhausen, A., Tonnus, W., Stumpf, J., Meyer, C., Othmar, E., Latk, M., Kanczkowski, W., Kroiss, M., Hantel, C., Hugo, C., Fassnacht, M., Ziegler, C.G., Schally, A.V., Krone, N.P. and Linkermann, A. (2019) Exquisite Sensitivity of Adrenocortical Carcinomas to Induction of Ferroptosis Proceedings of the National Academy of Science (PNAS) – in press
Fang, X., Wang, H., Han, D., Xie, E., Yang, X., Wie, J., Gu, S., Gao, F., Zhu, N., Yin, X., Cheng, Q., Zhang, P., Dai, W., Chen, J., Yang, F., Yang, H.-T., Linkermann, A.*, Gu, W.*, Min J. and Wang, F.* (2019) Ferroptosis as a novel target for protection against cardiomyopathy Proceedings of the National Academy of Science (PNAS) – Feb 12;116(7):2672-2680. *shared corresponding authors

Lafont, E., Draber P., Rieser E., Reichert M., Kupka S., de Miguel D., Draberova H., von Mässenhausen A., Bhamra A., Henderson S., Wojdyla K., Chalk A., Surinova S., Linkermann A. and Walczak, H. (2018) M1-ubiquitin- and NEMO-recruited TBK1/IKKε prevent TNF-induced cell death by RIPK1 phosphorylation Nature Cell Biology (NCB) – Dec;20(12):1389-1399

Gong Y.-N., Guy C., Olauson H., Becker J.U., Yang M., Fitzgerald P., Linkermann A.* and Green D.R.* (2017): ESCRT-III acts downstream of MLKL to regulate necroptotic cell death and its consequences. Cell Apr 6;169(2):286-300, *Corresponding authors

Martinez J., Cunha L., Park S., Yang M., Lu Q., Orchard R., Li Q.-Z., Yan M., Janke M., Guy C., Linkermann A., Virgin H. and Green D.R. (2016) LC3-associated phagocytosis links clearance of dying cells to auto-inflammation and lupus-like disease in mice Nature May 5;533(7601):115-9.

Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz PS, Weinlich R, Vanden Berghe T, Vandenabeele P, Pasparakis M, Bleich M, Weinberg JM, Reichel CA, Bräsen JH, Kunzendorf U, Anders HJ, Stockwell BR, Green DR, Krautwald S. (2014) Synchronized renal tubular cell death involves ferroptosis. Proceedings of the National Academy of Science (PNAS) 25;111(47):16836-41

Linkermann, A., Bräsen J.H., Darding, M., Jin, M.K., Sanz, A.B., Heller, J.-O., De Zen, F., Weinlich, R., Ortiz, A., Walczak, H., Weinberg, J.M., Green, D.R., Kunzendorf, U., Krautwald, S. (2013). Two Independent Pathways of Regulated Necrosis Mediate Ischemia-Reperfusion Injury, Proceedings of the National Academy of Science (PNAS) 16;110(29):12024-9.
Linkermann, A., Heller, J.-O., Prokai, A., Weinberg, J.M., De Zen, F., Himmerkus, N., Szabo, A.J., Bräsen, J.H., Kunzendorf, U., Krautwald, S. (2013).Osmotic Nephrosis and Contrast-Induced Acute Kidney Injury are prevented by the RIP1-kinase Inhibitor Necrostatin-1 in Mice. Journal of the American Society of Nephrology (JASN) Nov 24(10):1545-57.

Linkermann, A., Bräsen, J.H., Himmerkus, N., Liu, S., Huber, T.B., Kunzendorf, U., Krautwald, S. (2011). RIP1-mediated necroptosis essentially contributes to renal ischemia/reperfusion injury. Kidney International 81, 751-761.
Linkermann, A., Himmerkus, N., Rölver, L., Bleich, M., Bräsen, J.H., Kunzendorf, U., Krautwald, S. (2011). Blocking FasL in acute lethal Cisplatin induced renal failure prolongs survival in mice via two different mechanisms. Kidney International 79, 169-178