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Klinische Massenspektrometrie / Clinical Mass Spectrometry

Leitung:

Bild: mvogeser

Prof. Dr. med. Michael Vogeser

+49 89 4400-73221

 

Arbeitsgruppe:

Bild: mpaal

Dr. med. univ. Dr. rer. nat. Michael Paal, PhD

(Assistenzarzt)

+49 89 4400-73200

Bild: mpaal

Dr. rer. nat. Katharina Habler

(Lebensmittelchemikerin)

+49 89 4400-76248

cschuste

Dr. biol. hum. Carina Schuster

(Pharmazeutin)

+49 89 4400-76107

smoerlei

Sophie Rakete

(Dipl. Lebensmittelchemikerin)

+49 89 4400-76119

jschaeff

Judith Schäffler

(Pharmazeutin)

+49 89 4400-73119

  • Scientific Analytics and Translational Diagnostics: Development of mass spectrometry based methods for use in clinical diagnostic testing - Mass Spectrometry for Better Healthcare -
  • Therapeutic drug monitoring of antibiotics in intensive care medicine
  • Endocrinological profilling methods
  • Automation and integration in clinical application of mass spectrometry, Private-Public-Partnership projects
  • Exploring the perspectives of industrialized mass spectrometry applications in IVD
  • Quality, risk management and standardization in clinical applications of mass spectrometry
  • Prof. Vogeser is Editor of the Elsevier journal Clinical Mass Spectrometry / MSACL

 

Selected publications

Vogeser M. From therapeutic drug monitoring to total drug monitoring and drug-omics. Clin Chem Lab Med 2020 May 5. doi: 10.1515/cclm-2020-0339.

Habler K, Paal M, Vogeser M. Isotope dilution-LC-MS/MS Method for Quantification of the Urinary Cotinine-To-Creatinine Ratio. Clin Chem Lab Med 2020 Mar 25, doi: 10.1515/cclm-2020-0177.

Vogeser M, Stone JA. A suggested standard for validation of LC-MS/MS based analytical series in diagnostic laboratories. Clinical Mass Spectrometry 2020;16:25–32.

Vogeser M, Schuster C, Rockwood AL. A proposal to standardize the description of LC–MS-based measurement methods in laboratory medicine. Clinical Mass Spectrometry 2019; 13:36-38.

Schuster C, Paal M, Lindner J, Zoller M, Liebchen U, Scharf C, Vogeser M. Isotope dilution LC-orbitrap-HRMS with automated sample preparation for the simultaneous quantification of 11 antimycotics in human serum. J Pharm Biomed Anal 2019;166:398-405.

Lang R, Leinenbach A, Karl J, Swiatek-de Lange M, Kobold U, Vogeser M. An endoglycosidase-assisted LC-MS/MS-based strategy for the analysis of site-specific core-fucosylation of low-concentrated glycoproteins in human serum using prostate-specific antigen (PSA) as example. Clin Chim Acta 2018;480:1-8.

Vogeser M, Zhang YV. Understanding the strategic landscape surrounding the implementation of mass spectrometry in the clinical laboratory: A SWOT analysis. Clinical Mass Spectrometry 2018;9:1-6

Lindner JM, Vogeser M, Grimm SH. Biphenyl based stationary phases for improved selectivity in complex steroid assays. J Pharm Biomed Anal. 2017;142:66-73

Lucha S, Taibon J, Pongratz S, Geletneky C, Huber E, Wintterle-Roehm C, Lang R, Grimm SH, Duelffer T, Tarasov K, Zander J, Vogeser M, Kobold U. An LC-MS/MS based candidate reference method for the quantification of total gentamicin in human serum and plasma using NMR characterized calibrator material. Clin Chim Acta. 2016 Nov 19;464:211-217

Suhr AC, Bruegel M, Maier B, Holdt LM, Kleinhempel A, Teupser D, Grimm SH, Vogeser M. Ferromagnetic particles as a rapid and robust sample preparation for the absolute quantification of seven eicosanoids in human plasma by UHPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2016