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Klinische Massenspektrometrie / Clinical Mass Spectrometry


Bild: mvogeser

Prof. Dr. med. Michael Vogeser

+49 89 4400-73221



Bild: mpaal

Dr. med. univ. Dr. rer. nat. Michael Paal, PhD

+49 89 4400-73200


Carina Schuster (Pharmazeutin)

+49 89 4400-76107


Sophie Mörlein (Dipl. Lebensmittelchemikerin)

+49 89 4400-76119

Li Jian-Lüssi (Ärztin)

Anne Schliemann (cand. med.)

  • Scientific Analytics and Translational Diagnostics: Development of mass spectrometry based methods for use in clinical diagnostic testing - Mass Spectrometry for Better Healthcare -
  • Therapeutic drug monitoring of antibiotics in intensive care medicine
  • Endocrinological profilling methods
  • Automation and integration in clinical application of mass spectrometry, Private-Public-Partnership projects
  • Exploring the perspectives of industrialized mass spectrometry applications in IVD
  • Quality and risk management in clinical applications of mass spectrometry
  • Prof. Vogeser is Co-Editor-in-Chief of the Elsevier journal Clinical Mass Spectrometry


Selected publications

Vogeser M, Zhang YV. Understanding the strategic landscape surrounding the implementation of mass spectrometry in the clinical laboratory: A SWOT analysis. Clinical Mass Spectrometry 2018;9:1-6

Lindner JM, Vogeser M, Grimm SH. Biphenyl based stationary phases for improved selectivity in complex steroid assays. J Pharm Biomed Anal. 2017;142:66-73

Vogeser M, Seger C. Mass spectrometry methods in clinical diagnostics – state of the art and perspectives. Trends in Analytical Chemistry 2016

Vogeser M, Seger C. Quality management in clinical application of mass spectrometry measurement systems. Clin Biochem. 2016 Sep;49(13-14):947-54

Lucha S, Taibon J, Pongratz S, Geletneky C, Huber E, Wintterle-Roehm C, Lang R, Grimm SH, Duelffer T, Tarasov K, Zander J, Vogeser M, Kobold U. An LC-MS/MS based candidate reference method for the quantification of total gentamicin in human serum and plasma using NMR characterized calibrator material. Clin Chim Acta. 2016 Nov 19;464:211-217

Suhr AC, Bruegel M, Maier B, Holdt LM, Kleinhempel A, Teupser D, Grimm SH, Vogeser M. Ferromagnetic particles as a rapid and robust sample preparation for the absolute quantification of seven eicosanoids in human plasma by UHPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2016

Zander J, Maier B, Zoller M, Teupser D, Vogeser M. Quantification of linezolid in serum by LC-MS/MS using semi-automated sample preparation and isotope dilution internal standardization. Clin Chem Lab Med 2013

Baecher S, Geyer R, Lehmann C, Vogeser M. Absorptive chemistry based extraction for LC-MS/MS analysis of small molecule analytes from biological fluids - an application for 25-hydroxyvitamin D. Clin Chem Lab Med 2013

König K, Kobold U, Fink G, Leinenbach A, Dülffer T, Thiele R, Zander J, Vogeser M. Quantification of vancomycin in human serum by LC-MS/MS. Clin Chem Lab Med 2013

König K, Goethel SF, Rusu VM, Vogeser M. Deproteination of serum samples for LC-MS/MS analyses by applying magnetic micro-particles. Clin Biochem 2013

Vogeser M, Kirchhoff F, Geyer R. A novel approach to signal normalisation in atmospheric pressure ionisation mass spectrometry. J Pharmaceut Biomed Anal J Pharm Biomed Anal 2012

Kirchhoff F, Briegel J, Vogeser M. Quantification of free serum cortisol based on equilibrium dialysis and isotope dilution-liquid chromatography-tandem mass spectrometry. Clin Biochem 2011

Vogeser M, Seger C. Pitfalls associated with the use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) in the clinical laboratory. Clin Chem 2010