Publications (selected)
2019
Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A. LUBAC determines chemotherapy resistance squamous cell lung cancer. J Exp Med. 2019 Feb 4;216(2):450-465
2017
Demcollari TI, Cujba AM, Sancho R* (2017) Phenotypic plasticity in the pancreas: new triggers, new players. Curr Opin Cell Biol 49: 38-46. Invited by the special editors: Magdalena Gotz and Senthil Muthuswamy.
Ferreira RMM, Sancho R, Messal HA, Nye E, Spencer-Dene B, Stone RK, Stamp G, Rosewell I, Quaglia A, Behrens A (2017) Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression. Cell Rep 21: 966-978
2015
Sancho R*#, Cremona CA#, Behrens A* (2015) Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease. EMBO Rep 16: 571-81
2014
Sancho R, Gruber R, Gu G, Behrens A (2014) Loss of Fbw7 reprograms adult pancreatic ductal cells into alpha, delta, and beta cells. Cell Stem Cell 15: 139-53 *Selected as featured article of Cell Stem Cell issue Aug 7. Preview: Cell Stem Cell. 2014 Aug “Thinking outside of the F-box”
2013
Sancho R#, Blake SM#, Tendeng C, Clurman BE, Lewis J, Behrens A (2013) Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions. PLoS Biol 11: e1001586
2011
Loizou JI, Sancho R, Kanu N, Bolland DJ, Yang F, Rada C, Corcoran AE, Behrens A (2011) ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma. Cancer Cell 19: 587-600
Aguilera C#, Nakagawa K#, Sancho R, Chakraborty A, Hendrich B, Behrens A (2011) c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex. Nature 469: 231-5
2010
Sancho R, Jandke A, Davis H, Diefenbacher ME, Tomlinson I, Behrens A (2010) F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor. Gastroenterology 139: 929-41
2009
Sancho R, Nateri AS, de Vinuesa AG, Aguilera C, Nye E, Spencer-Dene B, Behrens A (2009) JNK signalling modulates intestinal homeostasis and tumourigenesis in mice. EMBO J 28: 1843-54