Publikationen 2010

1

Bai L, Beckers L, Wijnands E, Lutgens SP, Herías MV, Saftig P, Daemen MJ, Cleutjens K, Lutgens E, Biessen EA, Heeneman S. Cathepsin K genedisruption does not affect murine aneurysm formation. Atherosclerosis 2010;209:96-103. Pubmed  

2

Bampalis VG, Khandoga AL, Siess W. Fluoxetin inhibition of 5-HT-potentiated platelet aggregation in whole blood. Thromb Haemost 2010;104:1272-4. Pubmed  

3

Berres ML, Rueland A, Koenen RR, Moreno Zaldivar M, Schmitz P, Streetz KL, Gassler N, Weiskirchen R, Weber C, Trautwein C, Wasmuth HE. Antagonism of the chemokine CCL5 (RANTES) ameliorates experimental liver fibrosis in vivo. J Clin Invest 2010;120:4129-40. Pubmed  

4

Braunersreuther V, Pellieux C, Pelli G, Burger F, Steffens S, Montessuit C, Weber C, Proudfoot A, Mach F, Arnaud C. Chemokine CCL5/RANTES inhibition reduces myocardial reperfusion injury in atherosclerotic mice. J Mol Cell Cardiol 2010;48:789-98. Pubmed  

5

Drechsler M, Megens RT, van Zandvoort M, Weber C, Soehnlein O. Hyperlipidemia-triggered neutrophilia promotes early atherosclerosis. Circulation 2010;122:1837-45. Pubmed  

6

Dwivedi S, Pandey D, Khandoga AL, Brandl R, Siess W. Rac-1-mediated signalling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque. J Transl Med 2010;8:128. Pubmed  

7

Felker P, Sere K, Lin Q, Becker C, Hristov M, Hieronymus T, Zenke M. TGF-beta1 accelerates dendritic cell differentiation from common dendritic cell progenitors and directs subset specification toward conventional dendritic cells. J Immunol 2010;185:5326-35. Pubmed  

8

Gerdes N. From bystander to commander: how smooth muscle cells promote lymphoid tissue neogenesis. Arterioscler Thromb Vasc Biol 2010;30:393-4. Pubmed  

9

Goetzenich A, Hatam N, Zernecke A, Weber C, Czarnotta T, Autschbach R, Christiansen S. Alteration of matrix metalloproteinases in selective left ventricular adriamycin-induced cardiomyopathy in the pig. J Heart Lung Transplant 2010;28:1087-93. Pubmed  

10

Goossens P, Gijbels MJ, Zernecke A, Eijgelaar W, Vergouwe MN, van der Made I, Vanderlocht J, Beckers L, Buurman WA, Daemen MJ, Kalinke U, Weber C, Lutgens E, de Winther MP. Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions. Cell Metab 2010;12:142-53. Pubmed  

11

Grommes J, Soehnlein O. Contribution of neutrophils to acute lung injury. Mol Med 2010;17:293-307. Pubmed  

12

Hristov M, Gümbel D, Shagdasuren E, Lutgens E, Zernecke A, Weber C. Soluble CD40 ligand impairs the function of peripheral blood angiogenic outgrowth cells and increases neointimal formation after arterial injury. Circulation  2010;121:315-24. Pubmed  

13

Hristov M, Leyendecker T, Schuhmann C, von Hundelshausen P, Heussen N, Kehmeier E, Krötz F, Sohn HY, Klauss V, Weber C. Circulating monocyte subsets and cardiovascular risk factors in coronary artery disease. Thromb Haemost 2010;104:412-4. Pubmed  

14

Hristov M, Schmitz S, Schuhmann C, Leyendecker T, von Hundelshausen P, Krötz F, Sohn HY, Nauwelaers FA, Weber C. An optimized flow cytometry protocol for analysis of angiogenic monocytes and endothelial progenitor cells in peripheral blood. Cytometry A 2010;75:848-53. Pubmed  

15

Jung C, Gerdes N, Fritzenwanger M, Figulla HR. Circulating levels of interleukin-1 family cytokines in overweight adolescents. Mediators Inflamm 2010:958403. Pubmed  

16

Kenne E, Soehnlein O, Genové G, Rotzius P, Eriksson EE, Lindboom L. Immune cell recruitment to inflammatory loci is impaired in mice deficient in basement membrane protein laminin alpha 4. J Leukoc Biol 2010;88:523-8. Pubmed  

17

Khandoga AL, Pandey D, Welsch U, Brandl R, Siess W. GPR92/LPA5 lysophosphatidate receptor mediates megakaryocytic cell shape change induced by human atherosclerotic plaques. Cardiovasc Res 2010;90:157-64. Pubmed  

18

Koenen RR, Weber C. Manipulating the chemokine system: therapeutic perspectives for atherosclerosis. Curr Opin Investig Drugs 2010;11:265-72. Pubmed  

19

Koenen RR, Weber C. Therapeutic targeting of chemokine interactions in atherosclerosis. Nat Rev Drug Discov 2010;9:141-53. Pubmed  

20

Koenen RR, Weber C. Platelet-derived chemokines in vascular remodeling and atherosclerosis. Semin Thromb Haemost 2010;36:163-9. Pubmed  

21

Kraemer S, Lue H, Zernecke A, Kapurniotu A, Andreetto E, Frank R, Lennartz B, Weber C, Bernhagen J. MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based two-site binding mechanism. FASEB J 2010;25:894-906. Pubmed  

22

Kramp B, Sarabi A, Koenen RR, Weber C. Heterophilic chemokine receptor interactions in chemokine signaling and biology. Exp Cell Res 2010;317:655-663. Pubmed  

23

Liehn EA, Piccinini A, Koenen RR, Fatu R, Soehnlein O, Kungl A, Weber C. A potent CCL2 antagonist suitable for combined treatment of vascular and ischemia-reperfusion injury. J Am Coll Cardiol 2010;56:1847-57. Pubmed  

24

Lievens D, Gerdes N, Schober A, Weber C. Atherosclerosis: cell biology and lipoproteins. Curr Opin Lipidol 2010; 21:284-5. Pubmed  

25

Lievens D, Zernecke A, Seijkens T, Soehnlein O, Beckers L, Munnix IC, Wijnands E, Goossens P, van Kruchten R, Thevissen L, Boon L, Flavell RA, Noelle RJ, Gerdes N, Biessen EA, Daemen MJ, Heemskerk JW, Weber C, Lutgens E. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood 2010;116:4317-2. Pubmed  

26

Linder A, Soehnlein O, Akesson P. Roles of Heparin-Binding Protein in Bacterial Infections. J Innate Immune 2010;2:431-8. Pubmed  

27

Lip GYH, Preissner KT, Weber C. Editor`s choice articles 2008-2009. Thromb Haemost 2010;103:3-6.  

28

Loges S, Schmidt T, Tjwa M, van Geyte K, Lievens D, Lutgens E, Vanhoutte D, Borgel D, Plaisance S, Hoylaerts M, Luttun A, Dewerchin M, Jonckx B, Carmeliet P. Malignant cell fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6. Blood 2010;115(11):2264-73. Pubmed  

29

Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, Seijkens T, Engel D, Cleutjens J, Keller AM, Naik SH, Boon L, Oufella HA, Mallat Z, Ahonen CL, Noelle RJ, de Winther MP, Daemen MJ, Biessen EA, Weber C. Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. J Exp Med 2010;207:391-404. Pubmed  

30

Lutgens E, Poggi M, Weber C. CD40L-CD40 fuel ignites obesity. Thromb Haemost 2010;103:694-5. Pubmed  

31

Mause SF, Ritzel E, Liehn EA, Hristov M, Bidzhekov K, Müller-Newen G, Soehnlein O, Weber C. Platelet microparticles enhance the vasoregenerative potential of angiogenic early outgrowth cells after vascular injury. Circulation 2010;122:495-506. Pubmed  

32

Mause SF, Weber C. Microparticles - protagonists of a novel communication network for intercellular information exchange. Circ Res 2010;107:1047-57. Pubmed  

33

Mause SF, Sampol J, Weber C, Dignant-George F. New horizons in vascular biology and thrombosis: Highlights from EMVBM 2009. Thromb Haemost 2010;104:421-3. Pubmed  

34

Meuwese MC, Broekhuizen LN, Kuikhoven M, Heeneman S, Lutgens E, Gijbels MJ, Nieuwdorf M, Peutz CJ, Stroes ES, Vink H, van den Berg BM. Endothelial surface layer degradation by chronic hyaluronidase infusion induces proteinuria in apolipoprotein E-deficient mice. PLoS One 2010;5:e14262. Pubmed  

35

Noels H, Weber C. Fractalkine as an important target of aspirin in the prevention of atherogenesis. Cardiovasc Drugs Ther 2010;24:1-3. Pubmed  

36

Penz S, Bernlochner I, Toth O, Calatzis A, Siess W. Selective and rapid monitoring of dual platelet inhibition by aspirin and P2Y12 antagonists by using multiple electrode aggregometry. Thromb J 2010;8:9. Pubmed  

37

Reininger AJ, Bernlochner I, Penz SM, Ravanat C, Smethurst P, Farndale RW, Gachet C, Brandl R, Siess W. A two-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques. J Am Coll Cardiol 2010;55:1147-58.Pubmed  

38

Ren M, Guo Q, Guo L, Lenz M, Qian F, Koenen RR, Xu H, Schilling AB, Weber C, Ye RD, Dinner AR, Tang WJ. Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme. EMBO J 2010;29:3952-66. Pubmed  

39

Rotzius P, Thams S, Soehnlein O, Kenne E, Tseng CN, Björkström NK, Malmberg KJ, Lindbom L, Eriksson EE. Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice. Am J Pathol 2010;177:493-50. Pubmed  

40

Sarabi A, Kramp B, Weber C, Koenen R, von Hundelshausen P. CXCL4L1 inhibits angiogenesis and induces undirected endothelial migration without affecting proliferation or monocyte recruitment. J Thromb Haemost 2010;9:209-19. Pubmed  

41

Saygili E, Schauerte P, Küppers F, Heck L, Weis J, Weber C, Schwinger RH, Hoffmann R, Schröder JW, Marx N, Rana OR. Electrical stimulation of sympathetic neurons induces autocrine/paracrine effects of NGF mediated by TrkA. J Mol Cell Cardiol 2010;49:79-87. Pubmed  

42

Saygili E, Schauerte P, Küppers F, Heck L, Weis J, Weber C, Schwinger RH, Hoffmann R, Schröder JW, Marx N, Rana OR. Acetylcholin as an age-dependent non-neuronal source in the heart. Autonomic Neuroscience: Basic and Clinical 2010;156:82-9. Pubmed  

43

Saygili E, Schauerte P, Pekassa M, Saygili E, Rackauskas G, Schwinger RHG, Weis J, Weber C, Marx N, Rana OR. Sympathetic neurons express and secrete MMP-2 and MT1-MMP to control nerve sprouting via pro-NGF conversion. Cell Mol Neurobiol 2010;31:17-25. Pubmed  

44

Schober L, Khandoga AL, Penz SM, Siess W. The EP3-agonist sulprostone, but not prostaglandin E2 potentiates platelet aggregation in human blood. Thromb Haemost 2010;103:1268-9. Pubmed  

45

Schreinemachers M, Doorschodt B, Florquin S, van den Bergh Weerman MA, Zernecke A, Idu M, Tolba R, van Gulik TM. Pulsatile perfusio preservation of warm ischaemia-damaged experimental kidney grafts. Br J Surg 2010;97:349-58.Pubmed  

46

Schwarz N, Pruessmeyer J, Hess MF, Pantaler E, Windoffer R, Voss M, Sarabi A, Weber C, Secchi AS, Uhlig S, Ludwig A. Requirements for leukocyte transmigration via the transmembrane chemokine CX3CL1. Cell Mol Life Sci 2010;67:4233-48. Pubmed  

47

Seijkens T, Engel D, Tjwa M, Lutgens E. The role of CD154 in hematopoietic development. Thromb Haemost 2010;10:693-701.  

48

Shagdarsuren E, Bidzhekov K, Mause SF, Simsekyilmaz S, Polakowski T, Hawlisch H, Gessner JE, Zernecke A, Weber C. C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice. Circulation  2010;122:1026-36. Pubmed  

49

Simons D, Grieb G, Hristov M, Pallua N, Weber C, Bernhagen J, Steffens G. Hypoxia-induced endothelial secretion of macrophage migration inhibitory factor and role in endothelial progenitor cell recruitment. J Cell Mol Med 2010;15:668-78. Pubmed  

50

Soehnlein O. An elegant defense: how neutrophils shape the immune response. Trends Immunol 2010;30:511-2. Pubmed  

51

Soehnlein O. Direct and alternative antimicrobial mechanisms of neutrophil-derived granule proteins. J Mol Med 2010;87:1157-64. Pubmed  

52

Soehnlein O, Drechsler M, Hristov M, Weber C. Functional alterations of myeloid cell subsets in hyperlipidaemia: relevance for atherosclerosis. J Cell Mol Med 2010;13:4293-303. Pubmed  

53

Soehnlein O, Eriksson S, Hjelmqvist H, Andersson A, Mörgelin M, Lindbom L, Rundgren M, Frithiof R. Anesthesia aggravates lung damage and precipitates hypotension in endotoxemic sheep. Shock 2010;34:412-9. Pubmed  

54

Soehnlein O, Lindbom L. Phagocyte partnership during the onset and resolution of inflammation. Nat Rev Immunol 2010;10:427-39. Pubmed  

55

Soehnlein O, Lindbom L, Weber C. Mechanisms underlying neutrophil-mediated monocyte recruitment. Blood 2009;114:4613-23. Pubmed  

56

Soehnlein O, Weber C, Lindbom L. Neutrophil granule proteins tune monocytic cell function. Trends Immunol 2009;30:538-46. Pubmed  

57

Subramanian P, Karshovska E, Reinhard P, Megens RT, Zhou Z, Akhtar S, Schumann U, Li X, van Zandvoort M, Ludin C, Weber C, Schober A. Lysophosphatidic acid receptors LPA1 and LPA3 promote CXCL12-mediated smooth muscle progenitor cell recruitment in neointima formation. Circ Res 2010;107:96-105. Pubmed  

58

Subramanian P, Schober A. Neointima formation after vascular injury: is it all about CD39? Thromb Haeost 2010;103:257-8. Pubmed  

59

van Triest HJ, Megens RT, van Assen HC, ter Haar Romeny BM, van Zandvoort MA. Arterial radius estimation from microscopic data using a new algorithm for circle parameter estimation. J Biomed Opt 2010;15:026012. Pubmed  

60

Vasina E, Heemskerk JW, Weber C, Koenen RR. Platelets and platelet-derived microparticles in vascular inflammatory disease. Inflamm Allergy Drug Targets 2010;9:346-54. Pubmed  

61

Weber C. Bedside to Bench:Far from the heart: Receptor cross talk in remote conitioning. Nat Med 2010;16:760-2. Pubmed  

62

Weber C. Obstacles and options in the quest for drug candidates against vascular disease. Thromb Haemost 2010;104:1-3. Pubmed  

63

Weber C, Lip GY. Moving forward with a new editorial team for Thrombosis and Haemostasis. Thromb Haemost 2010;103:1-2. Pubmed  

64

Weber C, Schober A, Zernecke A. MicroRNAs in arterial remodelling, inflammation and atherosclerosis. Curr Drug Targets 2010;11:950-6. Pubmed  

65

Wiesner C, Faix J, Himmel M, Bentzien F, Linder S. KIF5B and KIF3A/KIF3B kinesins drive MT1-MMP surface exposure, CD44 shedding, and extracellular matrix degradation in primary macrophages. Blood 2010;116:1559-69. Pubmed  

66

Zaldivar MM, Pauels K, von Hundelshausen P, Berres ML, Schmitz P, Bornemann J, Kowalska MA, Gassler N, Streetz KL, Weiskirchen R, Trautwein C, Weber C, Wasmuth HE. CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis. Hepatology 2010;51:1345-53. Pubmed  

67

Zernecke A, Weber C. Chemokines in the vascular inflammatory response of atherosclerosis. Cardiovasc Res 2010;86:192-201. Pubmed  

68

Zimmermann HW, Seidler S, Nattermann J, Gassler N, Hellerbrand C, Zernecke A, Tischendorf JJ, Luedde T, Weiskirchen R, Trautwein C, Tacke F. Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis. PLoS One 2010;5:e11049. Pubmed  

 

 
 
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