Coronary artery disease arising from atherosclerosis is a leading cause of death and morbidity worldwide. The underlying pathogenesis involves an imbalanced lipid metabolism and a maladaptive immune response entailing a chronic inflammation of the arterial wall. The review article by Weber & Noels in the current issue of Nature Medicine to systematically survey recently identified molecular mechanisms, translational developments and clinical strategies for targeting lipid-related inflammation in atherosclerosis and CAD.
Publikation:
Atherosclerosis: current pathogenesis and therapeutic options
Christian Weber & Heidi Noels
Nature Medicine, 07. November 2011
Ansprechpartner:
Professor Christian Weber
Leitung des Instituts für Prophylaxe und Epidemiologie der Kreislaufkrankheiten am Klinikum der Universität München
Tel.: 089 / 5160 - 4351
Fax: 089 / 5160 - 4352
E-Mail: kreislaufinstitut@med.uni-muenchen.de
Web: ipek.klinikum.uni-muenchen.de
For more informatin read the following paper:
pubmed
