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Review on Atherosclerosis in Nature Medicine

Coronary artery disease arising from atherosclerosis is a leading cause of death and morbidity worldwide. The underlying pathogenesis involves an imbalanced lipid metabolism and a maladaptive immune response entailing a chronic inflammation of the arterial wall. The review article by Weber & Noels in the current issue of Nature Medicine to systematically survey recently identified molecular mechanisms, translational developments and clinical strategies for targeting lipid-related inflammation in atherosclerosis and CAD.



Atherosclerosis: current pathogenesis and therapeutic options

Christian Weber & Heidi Noels

Nature Medicine, 07. November 2011



Professor Christian Weber

Leitung des Instituts für Prophylaxe und Epidemiologie der Kreislaufkrankheiten am Klinikum der Universität München

Tel.: 089 / 5160 - 4351

Fax: 089 / 5160 - 4352




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