Publications

Gar C, Haschka SJ, Kern-Matschilles S, Rauch B, Sacco V, Prehn C, Adamski J, Seissler J, Wewer Albrechtsen NJ, Holst JJ, Lechner A. The liver-alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels. Diabetologia. 2020 Dec 4. doi: 10.1007/s00125-020-05334-x. (PubMed)

Reif S, Moschko S, Gar C, Ferrari U, Hesse N, Sommer NN, Seißler J, Lechner A. No Independent Association of Circulating Fetuin-A with Insulin Sensitivity in Young Women. Horm Metab Res. 2020 Nov;52(11):809-814. doi: 10.1055/a-1216-4405. Epub 2020 Aug 6. (PubMed)

Fueessl LU, Rottenkolber M, Gar C, Potzel AL, Keilen J, Seissler J, Lechner A. No deleterious effect of an additional pregnancy on glucose metabolism in women with previous gestational diabetes mellitus. Diabetes Res Clin Pract. 2020 Nov 21;171:108543. doi: 10.1016/j.diabres.2020.108543 (PubMed)

Sacco V, Rauch B, Gar C, Haschka S, Potzel AL, Kern-Matschilles S, Banning F, Benz I, Meisel M, Seissler J, Lechner A. Overweight/obesity as the potentially most important lifestyle factor associated with signs of pneumonia in COVID-19. PLoS One. 2020 Nov 18;15(11):e0237799. doi: 10.1371/journal.pone.0237799. eCollection 2020. PMID: 33206653 (PLoSONE)

Gar C, Rottenkolber M, Haenelt M, Potzel AL, Kern-Matschilles S, Then C, Seissler J, Bidlingmaier M, Lechner A. Altered metabolic and hormonal responses to moderate exercise in overweight/obesity. Metabolism. 2020 Jun; 107:154219. doi:0.1016/j.metabol.2020.154219. Epub 2020 Mar 30. PMID: 32240726 (PubMed)

Froelich MF, Fugmann M, Daldrup CL, Hetterich H, Coppenrath E, Saam T, Ferrari U, Seissler J, Popp D, Lechner A, Sommer NN. Measurement of total and visceral fat mass in young adult women: A comparison of MRI with anthropometric measurements with and without bioelectrical impedance analysis. Br J Radiol. 2020 Mar 6:20190874. doi: 10.1259/bjr.20190874 (PubMed)

Zaharia OP, Strassburger K, Strom A, Bönhof GJ, Karusheva Y, Antoniou S, Bódis K, Markgraf DF, Burkart V, Müssig K, Hwang JH, Asplund O, Groop L, Ahlqvist E, Seissler J, Nawroth P, Kopf S, Schmid SM, Stumvoll M, Pfeiffer AFH, Kabisch S, Tselmin S, Häring HU, Ziegler D, Kuss O, Szendroedi J, Roden M; German Diabetes Study Group. Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study. Lancet Diabetes Endocrinol. 2019 Sep;7(9):684-694. doi: 10.1016/S2213-8587(19)30187-1. Epub 2019 Jul 22 (PubMed)

Fritsche L, Sarief M, Wagner R, Stefan N, Lehmann R, Häring HU, Grallert H, Fritsche A, Lechner A. Genetic variation in TCF7L2 rs7903146 and history of GDM negatively and independently impact on diabetes-associated metabolic traits. Diabetes Res Clin Pract. 2018 Dec;146:251-257. doi: 10.1016/j.diabres.2018.11.003. Epub 2018 Nov 10 (PubMed)

Popp D, Aertsen S, Luetke-Daldrup C, Coppenrath E, Hetterich H, Saam T, Rottenkolber M, Seissler J, Lechner A, Sommer NN. No Correlation of Pancreatic Fat and β-Cell Function in Young Women With and Without a History of Gestational Diabetes. J Clin Endocrinol Metab. 2018 Sep 1;103(9):3260-3266. doi: 10.1210/jc.2018-00187 (PubMed)

Gar C, Rottenkolber M, Sacco V, Moschko S, Banning F, Hesse N, Popp D, Hübener C, Seissler J, Lechner A. Patterns of Plasma Glucagon Dynamics Do Not Match Metabolic Phenotypes in Young Women. J Clin Endocrinol Metab. 2018 Mar 1;103(3):972-982. doi: 10.1210/jc.2017-02014 (PubMed)

Ferrari U, Banning F, Freibothe I, Tröndle K, Sacco V, Wichmann C, Reif S, Moschko S, Potzel A, Gar C, Sommer NN, Popp D, Seissler J, Lechner A, Künzel H. Depressive symptoms, impaired glucose metabolism, high visceral fat, and high systolic blood pressure in a subgroup of women with recent gestational diabetes. J Psychiatr Res. 2018 Feb;97:89-93. doi: 10.1016/j.jpsychires.2017.12.001. Epub 2017 Dec 5 (PubMed)

Rieblinger B, Fischer K, Kind A, Saller BS, Baars W, Schuster M, Wolf-van Buerck L, Schäffler A, Flisikowska T, Kurome M, Zakhartchenko V, Kessler B, Flisikowski K, Wolf E, Seissler J, Schwinzer R, Schnieke A. Strong xenoprotective function by single-copy transgenes placed sequentially at a permissive locus. Xenotransplantation. 2018 Mar;25(2):e12382. doi: 10.1111/xen.12382. Epub 2018 Jan 23 (PubMed)

Banning F, Rottenkolber M, Freibothe I, Seissler J, Lechner A. Insulin secretory defect in familial partial lipodystrophy Type 2 and successful long-term treatment with a glucagon-like peptide 1 receptor agonist. Diabet Med. 2017 (PubMed)

Gar C, Rottenkolber M, Prehn C, Adamski J, Seissler J, Lechner A. Serum and Plasma amino acids as markers of prediabetes, insulin resistance, and incident diabetes. Crit Rev Clin Lab Sci. 2018 Jan;55(1):21-32. doi: 10.1080/10408363.2017.1414143. Epub 2017 Dec 14 (PubMed)

Ott B, Skurk T, Lagkouvardos L, Fischer S, Büttner J, Lichtenegger M, Clavel T, Lechner A, Rychlik M, Haller D, Hauner H. Short-Term Overfeeding with Dairy Cream Does Not Modify Gut Permeability, the Fecal Microbiota, or Glucose Metabolism in Young Healthy Men. J Nutr. 2018 Jan 1;148(1):77-85. doi: 10.1093/jn/nxx020 (PubMed)

Breier M, Wahl S, Prehn C, Ferrari U, Sacco V, Weise M, Grallert H, Adamski J, Lechner A. Immediate reduction of serum citrulline but no change of steroid profile after initiation of metformin in individuals with type 2 diabetes. J Steroid Biochem Mol Biol. 2017 Nov;174:114-119. doi: 10.1016/j.jsbmb.2017.08.004. Epub 2017 Aug 8 (PubMed)

Gar C, Rottenkolber M, Grallert H, Banning F, Freibothe I, Sacco V, Wichmann C, Reif S, Potzel A, Dauber V, Schendell C, Sommer NN, Wolfarth B, Seissler J, Lechner A, Ferrari U. Physical fitness and plasma leptin in women with recent gestational diabetes. PLoS One. 2017 Jun 13;12(6):e0179128. doi: 10.1371/journal.pone.0179128. eCollection 2017 (PubMed)

Wolf-van Buerck, Schuster M, Oduncu FS, Baehr A, Mayr T, Guethoff S, Abicht J, Reichart B, Klymiuk N, Wolf E, Seissler J. LEA29Y expression in transgenic neonatal porcine islet-like cluster promotes long-lasting xenograft survival in humanized mice without immunosuppressive therapy. Sci Rep. 2017 Jun 15;7(1):3572. doi: 10.1038/s41598-017-03913-4 (PubMed)

Kahnert K, Lucke T, Biertz F, Lechner A, ... COSYCONET study group. Transfer factor for carbon monoxide in patients with COPD and diabetes: results form the German COSYCONET cohort. Respri Res. 2017 Jan 13;18(1):14. doi: 10.1186/s12931-016-0499-0 (PupMed)

Shariful Islam SM, Lechner A, Ferrari U, Laxy M, Seissler J, Brown J, Niessen LW, Holle R. Healthcare use and expenditure for diabetes in Bangladesh. BMJ Glob Health. 2017 Jan 3;2(1):e000033. doi: 10.1136/bmjgh-2016-000033. eCollection 2017 (PubMed)

Kemter E, Cohrs CM, Schäfer M, Schuster M, Steinmeyer K, Wolf-van Buerck L, Wolf A, Wuensch A, Kurome M, Kessler B, Zakhartchenko V, Loehn M, Ivashchenko Y, Seissler J, Schulte AM, Speier S, Wolf E. INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters. Diabetologia. 2017 Jun;60(6):1152-1156. doi: 10.1007/s00125-017-4250-2. Epub 2017 Mar 18. (PubMed)

Seissler J. Stand und Perspektiven der Inselzell-Xenotransplantation. Info Diabetologie 2017 11 (4): 31-36

Chow CK, Islam SM, Farmer A, Bobrow K, Maddision R, Whittaker R, Dale LP, Lechner A, Niessen L, Lear SA, Eapen ZJ, Santo K, Stepien S, Redfern J, Rodgers A. Text2PreventCVD: protocol for a systematic review and individual participant data meta-analysis of text message-based interventions for the prevention of cardiovascular diseases. BMJ Open. 2016 Oct 17;6(10):e012723. doi: 10.1136/bmjopen-2016-012723 (PubMed)

Safita N, Islam SM, Chow CK, Niessen L, Lechner A, Holle R, Laxy M. The impact of type 2 diabetes on health related quality of life in Bangladesh: results from a matched study comparing treated cases with non-diabetic controls. Health Qual Life Outcomes. 2016 Sep 13;14(1):129. doi: 10.1186/s12955-016-0530-7 (PubMed)

Then C, Rottenkolber M, Lechner A, Meisinger C, Heier M, Koenig W, Peters A, Rathmann W, Bidlingmaier M, Reincke M, Seissler J. Altered relation of the renin-aldosterone system and vasoactive peptides in type 2 diabetes: The KORA F4 study. Atherosclerosis. 2016 Sep;252:88-96. doi: 10.1016/j.atherosclerosis.2016.07.905. Epub 2016 Jul 17 (PubMed)

Then C, Rottenkolber M, Lechner A, Meisinger C, Heier M, Koenig W, Peters A, Rathmann W, Bidlingmaier M, Reincke M, Seissler J. Dataset of the associations of aldosterone to renin ratio with MR-proANP and MR-proADM. Data Brief. 2016 Aug 9;8:1395-9. doi: 10.1016/j.dib.2016.08.008. eCollection 2016 Sep (PubMed)

Shariful Islam SM, Lechner A, Ferrari U, Seissler J, Holle R, Niessen LW. Mobile phone use and willingness to pay for SMS for diabetes in Bangladesh. J Public Health (Oxf). 2016 Mar;38(1):163-9. doi: 10.1093/pubmed/fdv009. Epub 2015 Feb 16 (PubMed)

Maier F, Demmelmair H, Fugmann M, Hellmuth C, Lechner A, Koletzko B, Uhl O. Contribution oflycerophospholipids and sphingomyelin to the circulating NEFA. Prostaglandins Leukot Essent Fatty Acids. 2016 Jul;110:55-61. doi: 10.1016/j.plefa.2016.01.004. Epub 2016 Feb 6 (PubMed)

Klymiuk N, Ludwig B, Seissler J, Reichart B, Wolf E. Current concepts of using pigs as a source for beta-cell replacement therapy of type 1 diabetes. Current Mol Biol Rep 2016 2:73-82

Wolf-van Buerck L, Schuster M, Baehr A, Mayr T, Guethoff S, Abicht J, Reichart B, Nam-Apostolopoulos YC, Klymiuk N, Wolf E, Seissler J. Engraftment and reversal of diabetes after intramuscular transplantation of neonatal porcine islet-like clusters. Xenotransplantation. 2015 Nov-Dec;22(6):443-50. doi: 10.1111/xen.12201. Epub 2015 Oct 21 (PubMed)

Islam SM, Ferrari U, Seissler J, Niessen L, Lechner A. Association between depression and diabetes amongst adults in Bangladesh: a hospital based case-control study. J Glob Health. 2015 Dec;5(2):020406. doi: 10.7189/jogh.05.020406. (PubMed)

Plotzki E, Buerck LW, Knauf Y, Becker T, Maetz-Rensing K, Schuster M, Baehr A, Klymiuk N, Wolf E, Seissler J, Denner J. Virus safety of islet cell transplantation from transgenic pigs to marmosets. Virus Res. 2015 Jun 2;204:95-102. doi: 10.1016/j.virusres.2015.04.016. Epub 2015 May 6 (PubMed)

Adolf C, Freibothe I, Seißler J, Lechner A . Current concepts in diagnostics and therapy of diabetes mellitus. Radiologe. 2015 Apr;55(4):295-8. (PubMed)

Then C, Kowall B, Lechner A, Meisinger C, Heier M, Koenig W, Peters A, Rathmann W, Seissler J. Plasma copeptin is associated with type 2 diabetes in men but not in women in the population-based KORA F4 study. Acta Diabetol. 2015 Feb;52(1):103-12. (PubMed)

Navti LK, Ferrari U, Tange E, Parhofer KG, Pozza SB. Height-obesity relationship in school children in Sub-Saharan Africa: results of a cross-sectional study in Cameroon. BMC Res Notes. 2015 Mar 26;8:98 (PubMed)

Reichart B, Niemann H, Chavakis T, Denner J, Jaeckel E, Ludwig B, Marckmann G, Schnieke A, Schwinzer R, Seissler J, Tönjes RR, Klymiuk N, Wolf E, Bornstein SR. Xenotransplantation of porcine islet cells as a potential option for the treatment of type 1 diabetes in the future. Horm Metab Res. 2015 Jan;47(1):31-5. doi: 10.1055/s-0034-1395518. Epub 2014 Dec 15 (PubMed)

Arndt B, Witkowski L, Ellwart J, Seissler J. CD8+ CD122+ PD-1- effector cells promote the development of diabetes in NOD mice. J Leukoc Biol. 2015 Jan;97(1):111-20. doi: 10.1189/jlb.3A0613-344RR. Epub 2014 Nov 11 (PubMed)

Islam SM, Alam DS, Wahiduzzaman M, Niessen LW, Froeschl G, Ferrari U, Lechner A. Clinical characteristics and complications of patients with type 2 diabetes attending an urban hospital in Bangladesh. Diabetes Metab Syndr. 2015 Jan-Mar;9(1):7-13. doi: 10.1016/j.dsx.2014.09.014. Epub 2014 Oct 13 (PubMed)

Fugmann M, Uhl O, Hellmuth C, Hetterich H, Kammer NN, …, Lechner A. Differences in the serum nonesterified Fatty Acid profile of young women associated with a recent history of gestational diabetes and overweight/obesity. PloS one. 2015 May 26;10(5):e0128001. doi: 10.1371/journal.pone.0128001. eCollection 2015 (PubMed)

Ferrari U, Künzel H, Tröndle K, Rottenkolber M, Kohn D, Fugmann M, Banning F, Weise M, Sacco V, Hasbargen U, Hutter S, Parhofer KG, Kloiber S, Ising M, Seissler J, Lechner A. Poor sleep quality is associated with impaired glucose tolerance in women after gestational diabetes. J Psychiatr Res. 2015;65:166-71. (PubMed)

Rottenkolber M, Ferrari U, Holland L, Aertsen S, Kammer NN, Hetterich H, Fugmann M, Banning F, Weise M, Sacco V, Kohn D, Freibothe I, Hutter S, Hasbargen U, Lehmann R, Grallert H, Parhofer KG, Seissler J, Lechner A. The Diabetes Risk Phenotype of Young Women With Recent Gestational Diabetes. J Clin Endocrinol Metab. 2015;100(6):E910-8. (PubMed)

Islam SM, Niessen LW, Ferrari U, Ali L, Seissler J, Lechner A. Effects of Mobile Phone SMS to Improve Glycemic Control Among Patients with Type 2 Diabetes in Bangladesh: A Prospective, Parallel-Group, Randomized Controlled Trial. Diabetes Care. 2015 Aug;38:e1-e2. (PubMed)

Islam SM, Niessen LW, Seissler J, Ferrari U, Biswas T, Islam A, Lechner A. Diabetes knowledge and glycemic control among patients with type 2 diabetes in Bangladesh. Springerplus. 2015 Jun 20;4:284. doi: 10.1186/s40064-015-1103-7 (manuscript)

Fugmann M, Breier M, Rottenkolber M, Banning F, Ferrari U, Sacco V, Grallert H, Parhofer KG, Seissler J, Clavel T, Lechner A. The stool microbiota of insulin resistant women with recent gestational diabetes, a high risk group for type 2 diabetes. Sci Rep. 2015 Aug 17;5:13212. doi: 10.1038/srep13212 (PubMed)

Klymiuk N*; van Bürck L*, Bähr A, Offers M, Kessler B, Wuensch A, Kurome M, Thormann M, Lochner K, Nagashima H, Herbach N, Wanke R, Seissler J^#, Wolf E^#. (gemeinsame *Erst- und ^#Letztautorenschaft). Xenografted islet-cell-clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice. Diabetes. 2012 Jun;61(6):1527-32. doi: 10.2337/db11-1325. Epub 2012 Apr 20 (PubMed)

Sattler C, Steinsdoerfer M, Offers M, Heseler K, Däubener W, Seissler J. Inhibition of T cell proliferation by murine multipotent mesenchymal stroma cells is mediated by CD39 expression and adenosine generation. Cell Transplantation 2011 20:1221-1230

Leicht SF, Schwarz TM, Hermann PC, Seissler J, Aicher A, Heeschen C. Adiponectin pretreatment counteracts the detrimental effect of a diabetic environment on endothelial progenitors. Diabetes 2011 60:652-661

Meisel R, Brockers S, Heseler K, Bülle H, Woite C, Stuhlsatz S, Schwippert W, Henschler R, Seissler J, Dilloo D, Däubener W. Human but not murine mesenchymal stem cells exhibit broad spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase. Leukemia 2011 25:648-654. 

Nath M, Offers M, Hummel M, Seissler J. Isolation and in vitro expansion of Lgr6-positive multipotent hair follicle stem cells. Cell Tissue Res. 2011 Jun;344(3):435-44. doi: 10.1007/s00441-011-1165-y. Epub 2011 Apr 12 (PubMed)