Publications (selected)

2019

• Hein R, Sake HJ, Pokoyski C, Hundrieser J, Brinkmann A, Baars W, Nowak-Imialek M, Lucas-Hahn A, Figueiredo C, Schuberth HJ, Niemann H, Petersen B, Schwinzer R. Triple (GGTA1, CMAH, B2M) modified pigs expressing an SLA class-I^low phenotype - effects on immune status and susceptibility to human immune responses. Am J Transplant. Nov 15. doi: 10.1111/ajt.15710. [Epub ahead of print]
  
  
• Sake HJ, Frenzel A, Lucas-Hahn A, Nowak-Imialek M, Hassel P, Hadeler KG, Hermann D, Becker R, Eylers H, Hein R, Baars W, Brinkmann A, Schwinzer R, Niemann H, Petersen B. Possible detrimental effects of beta-2-microglobulin knockout in pigs. Xenotransplantation. May 22:e12525. doi: 10.1111/xen.12525. [Epub ahead of print]

2018

• Buermann A, Petkov S, Petersen B, Hein R, Lucas-Hahn A, Baars W, Brinkmann A, Niemann H, Schwinzer R. Pigs expressing the human inhibitory ligand PD-L1 (CD 274) provide a new source of xenogeneic cells and tissues with low immunogenic properties. Xenotransplantation. Feb 15. doi: 10.1111/xen.12387. [Epub ahead of print]
  

2016

• Petersen B, Frenzel A, Lucas-Hahn A, Herrmann D, Hassel P, Klein S, Ziegler M, Hadeler KG, Niemann H. Efficient production of biallelic GGTA1 knockout pigs by cytoplasmic microinjection of CRISPR/Cas9 into zygotes. Xenotransplantation. Sep;23(5):338-46. doi: 10.1111/xen.12258. Epub 2016 Sep 9.

2013

• Gonzalez-Serrano, A.F., Pirro, V., Ferreira, C.R., Oliveri, P., Eberlin, L.S., Heinzmann, J., Lucas-Hahn, A., Niemann, H., Cooks, R.G. Desorption electrospray ionization mass spectrometry reveals lipid metabolism of individual oocytes and embryos. PLOS.ONE 8, e74981.
  
  
• Herrmann, D., Dahl, J.A., Lucas-Hahn, A., Collas, P., Niemann, H. Histone modifications and mRNA expression in the inner cell mass and trophectoderm of bovine blastocysts. Epigenetics 8, 281-289.
  
  
• Hauschild-Quintern, J., Petersen, B., Queisser, A.L., Lucas-Hahn, A., Schwinzer, R., Niemann, H. Gender non-specific efficacy of ZFN mediated gene targeting in pigs. Transgenic Research 22, 1-3.

2012

• Deshmukh, R.S., Østrup, O., Strejcek, F., Vejlsted, M., Lucas-Hahn, A., Petersen, B., Li, J., Callesen, H., Niemann, H., Hyttel, P. Early aberrations in chromatin dynamics in embryos produced under in vitro conditions. Cellular Reprogramming 14, 225-234.
  
  
• Niemann, H., Lucas-Hahn, A. Somatic cell nuclear transfer cloning: practical applications and current legislation. Reproduction in Domestic Animals 47, 2-10.

2011

• Nowak-Imialek, M., Kues, W.A., Petersen, B., Lucas-Hahn, A., Herrmann, D., Haridoss, S., Oropeza, M., Lemme, E., Schöler, H.R., Carnwath, J.W., Niemann, H. Oct4-EGFP transgenic pigs – a new large animal model for reprogramming studies. Stem Cells and Development 20, 1563–1575.
  
  
• Petersen B, Ramackers W, Lucas-Hahn A, Lemme E, Hassel P, Queißer A-L, et al. Transgenic expression of human heme oxygenase-1 in pigs confers resistance against xenograft rejection during ex vivo perfusion of porcine kidneys. Xenotransplantation; 18: 355–368.
  
  
• Hauschild, J., Petersen, B., Santiago, Y., Queisser, A.L., Carnwath, J.W., Lucas-Hahn, A. Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases. Proceedings of the National Academy of Sciences of the United States of America 108, 12013-12017.

2010

• Kuetemeyer, K., Lucas-Hahn, A., Petersen, B., Lemme, E., Hassel, P., Niemann, H., Heisterkamp, A. Combined multiphoton imaging and automated functional enucleation of porcine oocytes using femtosecond laser pulses. Journal of Biomedical Optics 15, 046006.
  
  
• Niemann, H., Carnwath, J.W., Herrmann, D., Wieczorek, G., Lemme, E., Lucas-Hahn, A., Olek, S. DNA methylation patterns reflect epigenetic reprogramming in bovine em

2008

• Nowak-Imialek M, Wrenzycki C, Herrmann D, Lucas-Hahn A, Lagutina I, Lemme E, Lazzari G, Galli C, Niemann H. Messenger RNA expression patterns of histone-associated genes in bovine preimplantation embryos derived from different origins. Mol Reprod Dev. May;75(5):731-43.