Urologische Klinik und Poliklinik » Forschung » Publikationen 2020

Publikationen 2020

Heteroresistant Bacteria Detected by an Extended Raman-based Antibiotic Susceptibility Test.
Anal Chem 2020;
Bauer D, Wieland K, Qiu L, Neumann-Cip AC, Magistro G, Stief CG, Wieser A, Haisch C

Regulation of smooth muscle contraction by monomeric non-RhoA GTPases.
Br J Pharmacol 2020;
Li B, Wang R, Wang Y, Stief CG, Hennenberg M

Establishment and Validation of an Individualized Cell Cycle Process-Related Gene Signature to Predict Cancer-Specific Survival in Patients with Bladder Cancer.
Cancers 2020; 12(5);
Shi R, Bao X, Rogowski P, Schäfer C, Schmidt-Hegemann NS, Unger K, Lu S, Sun J, Buchner A, Stief C, Belka C, Li M

Contrast-Enhanced Ultrasound (CEUS) for Follow-Up of Bosniak 2F Complex Renal Cystic Lesions-A 12-Year Retrospective Study in a Specialized European Center.
Cancers (Basel) 2020; 12(8)
Rübenthaler J, Čečatka S, Froelich MF, Stechele M, Marschner C, Sabel BO, Bogner F, Schnitzer ML, Overhoff D, Große Hokamp N, Staehler M, Schwarze V, Clevert DA

Total Penectomy for Recurrent Chordoma of the Corpus Cavernosum.
Case Rep Urol 2020;
Eismann L, Kess S, Stief CG, Strittmatter F

Pure high-grade papillary urothelial bladder cancer: a luminal-like subgroup with potential for targeted therapy.
Cell Oncol (Dordr) 2020;
Schnitzler T, Ortiz-Brüchle N, Schneider U, Lurje I, Guricova K, Buchner A, Schulz GB, Heidenreich A, Gaisa NT, Knüchel R, Garczyk S

Bladder Cancer Stage Development, 2004-2014 in Europe Compared With the United States: Analysis of European Population-based Cancer Registries, the United States SEER Database, and a Large Tertiary Institutional Cohort.
Clin Genitourin Cancer 2020; 18(3): 162-170.e4;
Schulz GB, Grimm T, Buchner A, Jokisch F, Kretschmer A, Stief CG, Knüchel R, Kraywinkel K, Karl A

Characterization of PD-1 and PD-L1 Expression in Papillary Renal Cell Carcinoma: Results of a Large Multicenter Study.
Clin Genitourin Cancer 2020;
Erlmeier F, Steffens S, Stöhr C, Herrmann E, Polifka I, Agaimy A, Trojan L, Ströbel P, Becker F, Wülfing C, Barth P, Stöckle M, Staehler M, Stief C, Haferkamp A, Hohenfellner M, Macher-Göppinger S, Wullich B, Noldus J, Brenner W, Roos FC, Walter B, Otto W, Burger M, Schrader AJ, Hartmann A, Ivanyi P, (German Network Of Kidney Cancer)

Patients' Perspective on Digital Technologies in Advanced Genitourinary Cancers.
Clin Genitourin Cancer 2020;
Rodler S, Buchner A, Stief CG, Heinemann V, Staehler M, Casuscelli J

Prospective evaluation of 4-D contrast-enhanced-ultrasound (CEUS) imaging in bladder tumors.
Clin Hemorheol Microcirc 2020; 74(1): 1-12;
Jokisch F, Buchner A, Schulz GB, Grimm T, Weinhold P, Pfitzinger PL, Chaloupka M, Stief CG, Schlenker B, Clevert DA

Lessons from the coronavirus disease 2019 pandemic: Will virtual patient management reshape uro-oncology in Germany?
Eur J Cancer 2020; 132(): 136-140;
Rodler S, Apfelbeck M, Stief C, Heinemann V, Casuscelli J

Correct use of non-indexed eGFR for drug dosing and renal drug-related problems at hospital admission.
Eur J Clin Pharmacol 2020;
Seiberth S, Bauer D, Schönermarck U, Mannell H, Stief C, Hasford J, Strobach D

PSMA PET/CT for tyrosine-kinase inhibitor monitoring in metastatic renal cell carcinoma.
Eur J Nucl Med Mol Imaging 2020;
Mittlmeier LM, Unterrainer M, Todica A, Cyran CC, Rodler S, Bartenstein P, Stief CG, Ilhan H, Staehler M

Onvansertib, a polo-like kinase 1 inhibitor, inhibits prostate stromal cell growth and prostate smooth muscle contraction, which is additive to inhibition by α1-blockers.
Eur J Pharmacol 2020;
Wang X, Li B, Ciotkowska A, Rutz B, Erlander MG, Ridinger M, Wang R, Tamalunas A, Waidelich R, Stief CG, Hennenberg M

Papillary vs clear cell renal cell carcinoma. Differentiation and grading by iodine concentration using DECT-correlation with microvascular density.
Eur Radiol 2020; 30(1): 1-10;
Marcon J, Graser A, Horst D, Casuscelli J, Spek A, Stief CG, Reiser MF, Rübenthaler J, Buchner A, Staehler M

Assessing the Best Surgical Template at Salvage Pelvic Lymph Node Dissection for Nodal Recurrence of Prostate Cancer After Radical Prostatectomy: When Can Bilateral Dissection be Omitted? Results from a Multi-institutional Series.
Eur Urol 2020;
Bravi CA, Fossati N, Gandaglia G, Suardi N, Mazzone E, Robesti D, Osmonov D, Juenemann KP, Boeri L, Jeffrey Karnes R, Kretschmer A, Buchner A, Stief C, Hiester A, Nini A, Albers P, Devos G, Joniau S, Van Poppel H, Shariat SF, Heidenreich A, Pfister D, Tilki D, Graefen M, Gill IS, Mottrie A, Karakiewicz PI, Montorsi F, Briganti A

Long-term Outcomes of Salvage Lymph Node Dissection for Nodal Recurrence of Prostate Cancer After Radical Prostatectomy: Not as Good as Previously Thought.
Eur Urol 2020;
Bravi CA, Fossati N, Gandaglia G, Suardi N, Mazzone E, Robesti D, Osmonov D, Juenemann KP, Boeri L, Jeffrey Karnes R, Kretschmer A, Buchner A, Stief C, Hiester A, Nini A, Albers P, Devos G, Joniau S, Van Poppel H, Shariat SF, Heidenreich A, Pfister D, Tilki D, Graefen M, Gill IS, Mottrie A, Karakiewicz PI, Montorsi F, Briganti A

Pretreatment Risk Stratification Tools for Prostate Cancer-Moving from Good to Better, Toward the Best.
Eur Urol 2020; 77(2): 189-190;
Herlemann A

Re: Clinical Efficacy and Biomarker Analysis of Neoadjuvant Atezolizumab in Operable Urothelial Carcinoma in the ABACUS Trial.
Eur Urol 2020;
Schulz GB, Black PC

Re: Randomized Trial of Partial Gland Ablation with Vascular Targeted Phototherapy Versus Active Surveillance for Low Risk Prostate Cancer: Extended Followup and Analyses of Effectiveness.
Eur Urol 2020;
Wirth M, Stief C, Stenzl A

The New Surveillance, Epidemiology, and End Results Prostate with Watchful Waiting Database: Opportunities and Limitations.
Eur Urol 2020;
Jeong CW, Washington SL, Herlemann A, Gomez SL, Carroll PR, Cooperberg MR

Urinary Frequency as a Possibly Overlooked Symptom in COVID-19 Patients: Does SARS-CoV-2 Cause Viral Cystitis?
Eur Urol 2020;
Mumm JN, Osterman A, Ruzicka M, Stihl C, Vilsmaier T, Munker D, Khatamzas E, Giessen-Jung C, Stief C, Staehler M, Rodler S

Health-related Quality of Life in Patients with Advanced Prostate Cancer: A Systematic Review.
Eur Urol Focus 2020;
Kretschmer A, Ploussard G, Heidegger I, Tsaur I, Borgmann H, Surcel C, Mathieu R, de Visschere P, Valerio M, van den Bergh RCN, Marra G, Thibault C, Ost P, Gandaglia G, Tilki D, EAU-YAU Prostate Cancer Working Party

Midterm Health-related Quality of Life After Radical Cystectomy: A Propensity Score-matched Analysis.
Eur Urol Focus 2020; 6(4): 704-710;
Kretschmer A, Grimm T, Buchner A, Jokisch F, Ziegelmüller B, Casuscelli J, Schulz G, Stief CG, Karl A

Telehealth in Uro-oncology Beyond the Pandemic: Toll or Lifesaver?
Eur Urol Focus 2020; 6(5): 1097-1103;
Rodler S, Apfelbeck M, Schulz GB, Ivanova T, Buchner A, Staehler M, Heinemann V, Stief C, Casuscelli J

Deferred Cytoreductive Nephrectomy Following Presurgical Vascular Endothelial Growth Factor Receptor-targeted Therapy in Patients with Primary Metastatic Clear Cell Renal Cell Carcinoma: A Pooled Analysis of Prospective Trial Data.
Eur Urol Oncol 2020;
de Bruijn R, Wimalasingham A, Szabados B, Stewart GD, Welsh SJ, Kuusk T, Blank C, Haanen J, Klatte T, Staehler M, Powles T, Bex A

Limitations of Available Studies Prevent Reliable Comparison Between Tumour Ablation and Partial Nephrectomy for Patients with Localised Renal Masses: A Systematic Review from the European Association of Urology Renal Cell Cancer Guideline Panel.
Eur Urol Oncol 2020; 3(4): 433-452;
Abu-Ghanem Y, Fernández-Pello S, Bex A, Ljungberg B, Albiges L, Dabestani S, Giles RH, Hofmann F, Hora M, Kuczyk MA, Kuusk T, Marconi L, Merseburger AS, Tahbaz R, Staehler M, Volpe A, Powles T, Lam TB, Bensalah K

Management of Sporadic Renal Angiomyolipomas: A Systematic Review of Available Evidence to Guide Recommendations from the European Association of Urology Renal Cell Carcinoma Guidelines Panel.
Eur Urol Oncol 2020; 3(1): 57-72;
Fernandéz-Pello S, Hora M, Kuusk T, Tahbaz R, Dabestani S, Abu-Ghanem Y, Albiges L, Giles RH, Hofmann F, Kuczyk MA, Lam TB, Marconi L, Merseburger AS, Powles T, Staehler M, Volpe A, Ljungberg B, Bex A, Bensalah K

Inhibition of Female and Male Human Detrusor Smooth Muscle Contraction by the Rac Inhibitors EHT1864 and NSC23766.
Front Pharmacol 2020;
Li B, Yu Q, Wang R, Gratzke C, Wang X, Spek A, Herlemann A, Tamalunas A, Strittmatter F, Waidelich R, Stief CG, Hennenberg M

Confronting hidden COVID-19 burden: a telemedical solution for elective urological outpatient clinics.
Infection 2020;
Westhofen T, Magistro G, Lennartz S, Casuscelli J, Stief C, Rodler S

First-line pazopanib in intermediate- and poor-risk patients with metastatic renal cell carcinoma: Final results of the FLIPPER trial.
Int J Cancer 2020;
Staehler M, Panic A, Goebell PJ, Merling M, Potthoff K, Herrmann E, de Geeter P, Vannier C, Hogrefe C, Marschner N, Grünwald V

Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma.
Int J Cancer 2020; 146(7): 2036-2046;
Gerke JS, Orth MF, Tolkach Y, Romero-Pérez L, Wehweck FS, Stein S, Musa J, Knott MML, Hölting TLB, Li J, Sannino G, Marchetto A, Ohmura S, Cidre-Aranaz F, Müller-Nurasyid M, Strauch K, Stief C, Kristiansen G, Kirchner T, Buchner A, Grünewald TGP

Rare patients in routine care: Treatment and outcome in advanced papillary renal cell carcinoma in the prospective German clinical RCC-Registry.
Int J Cancer 2020; 146(5): 1307-1315;
Staehler M, Goebell PJ, Müller L, Emde TO, Wetzel N, Kruggel L, Jänicke M, Marschner N, RCC-Registry Group (Tumour Registry of Advanced Renal Cell Carcinoma)

External validation of a postoperative nomogram for the prediction of disease-specific survival in patients with papillary renal cell carcinoma using a large multicenter database.
Int J Clin Oncol 2020; 25(1): 145-150;
Zastrow S, Krabbe LM, Wolff I, Capitanio U, Klatte T, Ecke T, Huck N, Borgmann H, Scavuzzo A, Cindolo L, Schips L, Surcel C, Mirvald C, Cabo AV, Musquera M, Hutterer G, Procházková K, Stief C, Wirth M, May M, Brookman-May S

EP3 Is an Independent Prognostic Marker Only for Unifocal Breast Cancer Cases.
Int J Mol Sci 2020; 21(12)
Zati Zehni A, Jeschke U, Hester A, Kolben T, Ditsch N, Jacob SN, Mumm JN, Heidegger HH, Mahner S, Vilsmaier T

Stereotactic Ablative Radiotherapy for ≥T1b Primary Renal Cell Carcinoma: A Report from the International Radiosurgery Oncology Consortium for Kidney (IROCK).
Int J Radiat Oncol Biol Phys 2020;
Siva S, Correa RJM, Warner A, Staehler M, Ellis RJ, Ponsky L, Kaplan ID, Mahadevan A, Chu W, Gandhidasan S, Swaminath A, Onishi H, Teh BS, Lo SS, Muacevic A, Louie AV

Open ureteroplasty with buccal mucosa graft for long proximal strictures: A good option for a rare problem.
Investig Clin Urol 2020; 61(3): 316-322;
Hefermehl LJ, Tritschler S, Kretschmer A, Beck V, Stief CG, Schlenker B, Strittmatter F

Safety, efficacy and prognostic impact of immune checkpoint inhibitors in older patients with genitourinary cancers.
J Geriatr Oncol 2020;
Schulz GB, Rodler S, Szabados B, Graser A, Buchner A, Stief C, Casuscelli J

Reply by Authors.
J Urol 2020;
Fossati N, Scarcella S, Gandaglia G, Suardi N, Robesti D, Boeri L, Karnes RJ, Heidenreich A, Pfister D, Kretschmer A, Buchner A, Stief C, Battaglia A, Joniau S, Van Poppel H, Osmonov D, Juenemann KP, Shariat S, Hiester A, Nini A, Albers P, Tilki D, Graefen M, Gill IS, Mottrien A, Galosi AB, Montorsi F, Briganti A

Underestimation of PET/CT Scan in Assessing Tumour Burden of Men With Nodal Recurrence From Prostate Cancer: Head-to-Head Comparison OF 68Ga-PSMA and 11C-Choline in a Large, Multi-Institutional Series of Extended Salvage Lymph Node Dissections.
J Urol 2020;
Fossati N, Scarcella S, Gandaglia G, Suardi N, Robesti D, Boeri L, Karnes RJ, Heidenreich A, Pfister D, Kretschmer A, Buchner A, Stief C, Battaglia A, Joniau S, Van Poppel H, Osmonov D, Juenemann KP, Shariat S, Hiester A, Nini A, Albers P, Tilki D, Graefen M, Gill IS, Mottrie A, Galosi AB, Montorsi F, Briganti A

Surgery for benign prostatic obstruction.
Lancet 2020; 396(10243): 5-7;
Magistro G, Stief CG

A matched-pair analysis of patients with medium-sized prostates (50 cc) treated for male LUTS with HoLEP or TURP.
Low Urin Tract Symptoms 2020; 12(2): 117-122;
Magistro G, Westhofen T, Stief CG, Weinhold P

How do elevated levels of testosterone affect the function of the human fallopian tube and fertility?-New insights.
Mol Reprod Dev 2020; 87(1): 30-44;
Dulohery K, Trottmann M, Bour S, Liedl B, Alba-Alejandre I, Reese S, Hughes B, Stief CG, Kölle S

The STK16 inhibitor STK16-IN-1 inhibits non-adrenergic and non-neurogenic smooth muscle contractions in the human prostate and the human male detrusor.
Naunyn Schmiedebergs Arch Pharmacol 2020; 393(5): 829-842;
Li B, Wang X, Rutz B, Wang R, Tamalunas A, Strittmatter F, Waidelich R, Stief CG, Hennenberg M

Comprehensive analysis of Twitter activity on #Incontinence.
Neurourol Urodyn 2020; 39(1): 440-446;
Grabbert M, Khoder WY, Gratzke C, Paffenholz P, Salem J, Bauer RM

Retropubic vs transobturator Argus adjustable male sling: Results from a multicenter study.
Neurourol Urodyn 2020;
Loertzer H, Huesch T, Kirschner-Hermanns R, Anding R, Rose A, Brehmer B, Naumann CM, Queissert F, Nyarangi-Dix J, Homberg R, Grabbert M, Hofmann T, Pottek T, Hübner W, Haferkamp A, Bauer RM, Kretschmer A

Improving patient-clinician communication following nephrectomy in renal cell carcinoma: Development, content validation and pilot testing of a conversation aid tool.
Patient Educ Couns 2020;
Bentley S, Johnson C, Exall E, Brohan E, Lawrance R, Bennett B, Bargo D, Zanotti G, Staehler M, Stewart GD

Fluorescence and Treatment Light Monitoring for Interstitial Photodynamic Therapy.
Photochem Photobiol 2020; 96(2): 388-396;
Heckl C, Aumiller M, Rühm A, Sroka R, Stepp H

MOP-dependent enhancement of methadone on the effectiveness of ALA-PDT for A172 cells by upregulating phosphorylated JNK and BCL2.
Photodiagnosis Photodyn Ther 2020;
Shi L, Pohla H, Buchner A, Zhang L, Pongratz T, Rühm A, Zimmermann W, Gederaas OA, Wang X, Stepp H, Sroka R

Inhibition of neurogenic and thromboxane A2 -induced human prostate smooth muscle contraction by the integrin α2β1 inhibitor BTT-3033 and the integrin-linked kinase inhibitor Cpd22.
Prostate 2020; 80(11): 831-849;
Li B, Wang X, Wang R, Rutz B, Ciotkowska A, Gratzke C, Herlemann A, Spek A, Tamalunas A, Waidelich R, Stief CG, Hennenberg M

Decipher identifies men with otherwise clinically favorable-intermediate risk disease who may not be good candidates for active surveillance.
Prostate Cancer Prostatic Dis 2020; 23(1): 136-143;
Herlemann A, Huang HC, Alam R, Tosoian JJ, Kim HL, Klein EA, Simko JP, Chan JM, Lane BR, Davis JW, Davicioni E, Feng FY, McCue P, Kim H, Den RB, Bismar TA, Carroll PR, Cooperberg MR

Multiparametric magnetic resonance imaging and multiparametric magnetic resonance imaging-guided biopsy in the diagnostic pathway of prostate cancer.
Radiologe 2020;
Chaloupka M, Apfelbeck M, Pfitzinger P, Bischoff R, Lellig E, Rath L, Schlenker B, Stief CG, Clevert D

Natural selection supports escape from concerted evolution of a recently duplicated CEACAM1 paralog in the ruminant CEA gene family.
Sci Rep 2020; 10(1)
Hänske J, Hammacher T, Grenkowitz F, Mansfeld M, Dau TH, Maksimov P, Friedrich C, Zimmermann W, Kammerer R

Epidemiology and Treatment Barriers of Patients With Erectile Dysfunction Using an Online Prescription Platform: A Cross-Sectional Study.
Sex Med 2020;
Rodler S, von Büren J, Buchner A, Stief C, Elkhanova K, Wülfing C, Jungmann S

Benefits and Limitations of Transurethral Resection of the Prostate Training With a Novel Virtual Reality Simulator.
Simul Healthc 2020; 15(1): 14-20;
Schulz GB, Grimm T, Kretschmer A, Stief CG, Jokisch F, Karl A

PSMA-positive nodal recurrence in prostate cancer : Salvage radiotherapy is superior to salvage lymph node dissection in retrospective analysis.
Strahlenther Onkol 2020;
Schmidt-Hegemann NS, Buchner A, Eze C, Rogowski P, Schaefer C, Ilhan H, Li M, Fendler WP, Bartenstein P, Ganswindt U, Stief C, Belka C, Kretschmer A

Impact of Routine Laboratory Parameters in Patients Undergoing Radical Cystectomy for Urothelial Carcinoma of the Bladder: A Long-Term Follow-Up.
Urol Int 2020; (): 1-8;
Tamalunas A, Buchner A, Kretschmer A, Jokisch F, Schulz G, Eismann L, Stief CG, Grimm T

Is It Safe to Offer Radical Cystectomy to Patients above 85 Years of Age? A Long-Term Follow-Up in a Single-Center Institution.
Urol Int 2020;
Tamalunas A, Volz Y, Schlenker BA, Buchner A, Kretschmer A, Jokisch F, Rodler S, Schulz G, Eismann L, Pfitzinger P, Stief CG, Grimm T

Long-Term Follow-Up and Oncological Outcome of Patients Undergoing Radical Cystectomy for Bladder Cancer following an Enhanced Recovery after Surgery (ERAS) Protocol: Results of a Large Randomized, Prospective, Single-Center Study.
Urol Int 2020; 104(1-2): 55-61;
Ziegelmueller BK, Jokisch JF, Buchner A, Grimm T, Kretschmer A, Schulz GB, Stief C, Karl A

Preoperative Thrombocytosis in Patients Undergoing Radical Cystectomy for Urothelial Cancer of the Bladder: An Independent Prognostic Parameter for an Impaired Oncological Outcome.
Urol Int 2020; 104(1-2): 36-41;
Jokisch JF, Grimm T, Buchner A, Kretschmer A, Weinhold P, Stief CG, Karl A, Schulz GB

[Chronic prostatitis/chronic pelvic pain syndrome].
Urologe A 2020; 59(6): 739-748;
Magistro G, Stief CG, Wagenlehner FME

[Use of synthetic slings and mesh implants in the treatment of female stress urinary incontinence and prolapse : Statement of the Working Group on Urological Functional Diagnostics and Female Urology of the Academy of the German Society of Urology].
Urologe A 2020; 59(1): 65-71;
Höfner K, Hampel C, Kirschner-Hermanns R, Alloussi SH, Bauer RM, Bross S, Bschleipfer T, Goepel M, Haferkamp A, Hüsch T, Kaufmann A, Kiss G, Kranz J, Oelke M, Pannek J, Reitz A, Rutkowski M, Schäfer W, Schulte-Baukloh H, Schumacher S, Seif C, Schultz-Lampel D

Can we define reliable risk factors for anastomotic strictures following radical prostatectomy?
Urologia 2020;
Spek A, Buchner A, Khury F, Khoder W, Tritschler S, Stief C

Advanced molecular imaging in histologically verified metanephric adenoma.
Urology 2020;
Mittlmeier LM, Unterrainer M, Todica A, Clevert DA, Cyran CC, Schmoeckel E, Rodler S, Bartenstein P, Stief CG, Ilhan H, Staehler M

Comparative evaluation of tissue damage induced by ultrasound and impact dual-mode endoscopic lithotripsy versus conventional single-mode ultrasound lithotripsy.
World J Urol 2020; 38(4): 1051-1058;
Khoder W, Strittmatter F, Alghamdi A, Seitz M, Stief C, Bader MJ

Comparison of stone elimination capacity and drilling speed of endoscopic clearance lithotripsy devices.
World J Urol 2020;
Bader MJ, Eisel M, Strittmatter F, Nagele U, Stief CG, Pongratz T, Sroka R, Training and Research in Urological Surgery and Technology (T.R.U.S.T.)-Group

Health-related quality of life after open and robot-assisted radical prostatectomy in low- and intermediate-risk prostate cancer patients: a propensity score-matched analysis.
World J Urol 2020;
Kretschmer A, Bischoff R, Chaloupka M, Jokisch F, Westhofen T, Weinhold P, Strittmatter F, Becker A, Buchner A, Stief CG

Impact of previous transurethral prostate surgery on health-related quality of life after radical prostatectomy: Does the interval between surgeries matter?
World J Urol 2020;
Chaloupka M, Figura F, Weinhold P, Jokisch F, Westhofen T, Pfitzinger P, Bischoff R, Magistro G, Strittmatter F, Becker A, Ormanns S, Schlenker B, Buchner A, Stief CG, Kretschmer A

The natural course of urinalysis after urinary diversion.
World J Urol 2020;
Magistro G, Zimmermann L, Bischoff R, Westhofen T, Grimm T, Schlenker B, Stief CG, Marcon J

The significance of a high preoperative PSA level for the detection of incidental prostate cancer in LUTS patients with large prostates.
World J Urol 2020;
Magistro G, Keller P, Westhofen T, Schott M, Tamalunas A, Weinhold P, Stief CG