FOR 2033

FOR 2033

 

Somatic stemcells are critical to maintain highly regenerative tussue such as the skin, the gastro-intestinal mucosa and the blood system. Hematopoietic stem cells (HSCs) are well understood somatic cells, which have been used successfully for clinical regenerative therapies. HSCs are located in the bone marrow, although the importance of their microenvironment, the so called niche has only recently been recognized. Despite the important role of hematopoietic niche, our knowledge of its biology is limited. The niche environment comprises various cell types, like osteoblasts, multipotent and perivascular stromal cells, as well as macrophages. More information on: http://www.for2033.med.tum.de