The role of shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells.
Photodiagnosis Photodyn Ther. 2022 Jun 24:102987. doi: 10.1016/j.pdpdt.2022.102987
Werner M, Lyu C, Stadlbauer B, Schrader I, Buchner A, Stepp H, Sroka R, Pohla H



Diagnostic and Prognostic Role of miR-192 in Different Cancers: A Systematic Review and Meta-Analysis.
Biomed Res Int 2021: 8851035
Wang L, Liu Y, Lyu C, Buchner A, Pohla H



Shikonin enhances the antitumor effect of cabazitaxel in prostate cancer stem cells and reverses cabazitaxel resistance by inhibiting ABCG2 and ALDH3A1.
Am J Cancer Res 2020; 10(11): 3784-3800
Wang L, Stadlbauer B, Lyu C, Buchner A, Pohla H

MOP-dependent enhancement of methadone on the effectiveness of ALA-PDT for A172 cells by upregulating phosphorylated JNK and BCL2.
Photodiagnosis Photodyn Ther 2020; 30: 101657
Shi L, Pohla H, Buchner A, Zhang L, Pongratz T, Rühm A, Zimmermann W, Gederaas OA, Wang X, Stepp H, Sroka R



Methadone enhances the effectiveness of 5-aminolevulinic acid-based photodynamic therapy for squamous cell carcinoma and glioblastoma in vitro.
J Biophotonics 2019; 12(10): e201800468
Shi L, Buchner A, Pohla H, Pongratz T, Rühm A, Zimmermann W, Gederaas OA, Zhang L, Wang X, Stepp H, Sroka R



Induction of porcine-specific regulatory T cells with high specificity and expression of IL-10 and TGF-?1 using baboon-derived tolerogenic dendritic cells.
Xenotransplantation. 2018;25(1)
Li M, Eckl J, Abicht JM, Mayr T, Reichart B, Schendel DJ, Pohla H



Li M, Eckl J, Geiger C, Schendel DJ, Pohla H. A novel and effective method to generate human porcine-specific regulatory T cells with high expression of IL-10, TGF-β1 and IL-35. Sci Rep. Jun 21;7(1):3974. (2017)

Chen D, Maruschke M, Hakenberg O, Zimmermann W, Stief CG, Buchner A. TOP2A, HELLS, ATAD2, and TET3 Are Novel Prognostic Markers in Renal Cell Carcinoma. Urology 102: 265.e1-265.e7 (2017)



Zimmermann W, Kammerer R. Coevolution of paired receptors in Xenopus carcinoembryonic antigen-related cell adhesion molecule families suggests appropriation as pathogen receptors. BMC Genomics BMC Genomics. 17(1):928 (2016)

Königer V, Holsten L, Harrison U, Busch B, Loell E, Zhao Q, Bonsor DA, Roth A, Kengmo-Tchoupa A, Smith SI, Mueller S, Sundberg EJ, Zimmermann W, Fischer W, Hauck CR, Haas R. Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA. Nat Microbiol. (2016)

Aleksic D, Blaschke L, Mißbach S, Hänske J, Weiß W, Handler J, Zimmermann W, Cabrera-Sharp V, Read JE, de Mestre AM, O'Riordan R, Moore T, Kammerer R. Convergent evolution of pregnancy-specific glycoproteins in the human and horse. Reproduction (2016)

Vetter E, Kronast M, Tölge M, Zimmermann W. Lgr5-expressing stem cells are not the cells of origin of pyloric neuroendocrine carcinomas in mice. J Pathol. 238(1): 42-51 (2016)



Gutbier B*, Fischer K*, Doehn J-M, von Lachner C, Herr C, Klaile E, Frischmann U, Singer BB, Riesbeck K, Zimmermann W, Suttorp N, Bachmann S, Bals R, Witzenrath M, Slevogt H. Moraxella catarrhalis induces an immune response in the murine lung which is independent of human CEACAM5 expression and long-term smoke exposure. Am J Physiol Lung Cell Mol Physiol, (2015)



Chen D, Gassenmaier M, Maruschke M, Riesenberg R, Pohla H, Stief CG, Zimmermann W, Buchner A. Expression and prognostic significance of a comprehensive epithelial-mesenchymal transition gene set in renal cell carcinoma. J Urol. 191(2): 479-86 (2014)

Maruschke M, Hakenberg OW, Koczan D, Zimmermann W, Stief CG, Buchner A. Identification of significant alterations of pathways in metastatic renal cell carcinoma using gene set enrichment analysis (GSEA). Int. J. Urol. 21(1): 46-51 (2014)

Hartmann T, Xu X, Kronast M, Muehlich S, Meyer K, Zimmermann W, Hurwitz J, Pan Z-Q, Engelhardt S, Sarikas A. Inhibition of Cullin-RING E3 ubiquitin ligase 7 by Simian Virus 40 large T antigen. Proc. Natl. Acad. Sci. USA 111(9): 3371-6 (2014)

Heckta T, Bickert T, Jeschkea A, Seitz S, Schulze J, Itoc WD, Zimmermann W, Amling M, Schinke T, Horst AK and Keller J. Increased osteoclastogenesis in mice lacking the carcinoembryonic antigen-related cell adhesion molecule 1. PLoS ONE, 9(12), e114360 (2014)



Brämswig K, Poettler M, Kalinowska W, Martel A, Wrba F, Binder BR, Zimmermann W, Ginsberg MH, Zielinski CC, Prager GW. A functional role of carcinoembryonic antigen (CEA) in tumor angiogenesis. Cancer Res. 73(22): 6584-96 (2013)

Pohla H*, Buchner A*, Stadlbauer B, Frankenberger B, Stevanovic S, Walter S, Frank R, Baron U, Olek S, Stief CG, Hofstetter A, Pezzutto A, Blankenstein T, Oberneder R, Schendel DJ. High immune response rate and decreased frequencies of regulatory T cells in patients with metastatic renal cell carcinoma after therapeutic tumor cell vaccination. Mol. Med. 18: 1499-508 (2013) *co-first authorship

Gassenmaier M, Chen D, Buchner A, Henkel L, Schiemann M, Mack B, Schendel DJ, Zimmermann W, Pohla H. CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis. Stem Cells 31: 1467-1476 (2013)

Buchner A, May M, Burger M, Bolenz C, Herrmann E, Fritsche HM, Ellinger J, Höfner T, Nuhn P, Gratzke C, Brookman-May S, Melchior S, Peter J, Moritz R, Tilki D, Gilfrich C, Roigas J, Zacharias M, Hohenfellner M, Haferkamp A, Trojan L, Wieland WF, Müller SC, Stief CG, Bastian PJ. Prediction of outcome in patients with urothelial carcinoma of the bladder following radical cystectomy using artificial neural networks. Eur. J. Surg. Oncol. 39(4): 372-9 (2013)

Yuan G, Regel I, Lian F, Friedrich T, Hofheinz R, Langer R, Röcken C, Zimmermann W, Schmid RM, Ebert MPA, Burgermeister E. WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells. Oncogene 32(3): 375-87 (2013)

Hachmeister M, Bobowski K, Hogl S, Dislich B, Fukumori A, Eggert C, Mack B, Kremling H, Sarrach S, Coscia F, Zimmermann W, Steiner H, Lichtenthaler SF, Gires O. Regulated intramembrane proteolysis and degradation of murine epithelial cell adhesion molecule mEpCAM. PLOS ONE 8(8): e71836 (2013)

Zhang H, Eisenried A, Zimmermann W, Shively JE. Role of CEACAM1 and CEACAM20 in an in vitro model of prostate morphogenesis. PLOS ONE 8(1): e53359 (2013)



Pohla H*, Buchner A*, Stadlbauer B, Frankenberger B, Stevanovic S, Walter S, Frank R, Schwachula T, Olek S, Kopp J, Willimsky G, Stief CG, Hofstetter A, Pezzutto A, Blankenstein T, Oberneder R, Schendel DJ. High immune response rates and decreased frequencies of regulatory T cells in metastatic renal cell carcinoma patients following tumor cell vaccination. Mol. Med. 18: 1499-1508 (2012) *co-first authorship

Buchner A, Kendlbacher M, Nuhn P, Tüllmann C, Haseke N, Stief CG, Staehler M. Outcome assessment of patients with metastatic renal cell carcinoma under systemic therapy using artificial neural networks. Clin. Genitourin. Cancer 10(1):37-42 (2012)

Eckl J*, Buchner A*, Prinz PU, Riesenberg R, Siegert S, Kammerer R, Nelson PJ, Noessner E. Transcript signature predicts tissue NK-cell content and defines renal cell carcinoma subgroups independent of TNM staging. J. Mol. Med. 90(1): 55-66 (2012) *co-first authorship

Ihler F, Vetter E, Pan J, Kammerer R, Debey-Pascher S, Schultze JL, Zimmermann W*, Enders G*. Expression of a neuroendocrine gene signature in gastric tumor cells from CEA424-SV40 large T antigen-transgenic mice depends on SV40 large T antigen. PlOS ONE, 7(1): e29846 (2012) *joint last author

Lechner-Tschoep KE, Drexler I, Hammer D, Neumann D, Pohla H, Sutter G, Noessner E, Issels R-D. Modified vaccinia virus Ankara delivers a robust surrogate marker for immune monitoring to sarcoma cells even if cells are being exposed to chemotherapy and heat treatment. Int. J. Hyperthermia 28(1): 33-42 (2012)

Regel I, Merkl L, Friedrich T, Burgermeister E, Zimmermann W, Einwächter H, Herrmann K, Langer R, Röcken C, Schmid RM, Ebert MPA. The pan-histone deacetylase inhibitor panobinostat (LBH589) overcomes anthracycline resistance in gastric cancer cells via induction of CITED2. Gastroenterology 143(1):99-109 (2012)

Kammerer R, Rüttiger L, Riesenberg R, Schäuble C, Krupar R, Kamp A, Sunami K, Eisenried A, Hennenberg M, Grunert F, Breß A, Battaglia S, Schrewe H, Knipper M, Schneider MR, Zimmermann W. Loss of the mammal-specific tectorial membrane component CEA cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies. J. Biol. Chem. 287: 21584-21598 (2012) - Pressemitteilung der LMU

Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C, Staehler M, Brugger W, Dietrich P-Y, Hilf N, Schoor O, Fritsche J, Mahr A, Mendrzyk R, Maurer D, Vass V, Trautwein C, Lewandrowski P, Flohr C, Pohla H, Stanczak JJ, Bronte V, Mandruzzato S, Biedermann T, Pawelec G, Derhovanessian E, Yamagishi H, Tsuneharu M, Hongo F, Takaha N, Hirakawa K, Tanaka H, Stevanovic S, Rammensee H-G, Frisch J, Mayer-Mokler A, Kirner A, Reinhard C, Singh-Jasuja H. Prolonged survival of patients with advanced renal cancer responding to multi-peptide vaccine IMA901 after single-dose cyclophosphamide. Nat. Med. (2012) Jul 29. doi: 10.1038/nm.2883



Westermann J, Flörcken A, Willimsky G, van Lessen A, Kopp J, Takvorian A, Jöhrens K, Lukowsky A, Schönemann C, Sawitzki B, Pohla H, Frank R, Dörken B, Schendel DJ, Blankenstein T, Pezzutto A. Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer – a clinical phase I study. Gene Ther., 18(4): 354-63 (2011)

Figel AM, Brech D, Prinz PU, Lettenmeyer UK, Hosse J, Turqueti-Neves A, Mysliwietz J, Anz D, Rieth N, Muenchmeier N, Buchner A, Porubsky S, Siegert S, Segerer S, Nelson PJ, Noessner E. Human renal cell carcinoma induces a dendritic cell subset that uses T cell crosstalk for tumor-permissive milieu alterations. Am. J. Pathol. 179(1): 436-51 (2011)

Kammerer R, Buchner A, Palluch P, Pongratz T, Oboukhovskij K, Beyer W, Johansson A, Stepp H, Baumgartner R, Zimmermann W. Induction of immune mediators in glioma and prostate cancer cells by non-lethal photodynamic therapy. PloS ONE 6(6): e21834 (2011)

Burgermeister E, Friedrich T, Hitkova I, Gruner I, Einwächter H, Zimmermann W, Schaefer C, Röcken C, Perren A, Schmid RM, Seger R, Ebert MPA. The ras inhibitors caveolin-1 and docking protein-1 activate PPARgamma through spatial relocalization at helix-7 of its ligand-binding domain. Compartmentalization of peroxisome proliferator-activated receptor-gamma by the scaffold protein caveolin-1 in human gastric cancer. Mol. Cell. Biol. 31(16): 3497-510 (2011)

van den Engel NK, Rüttinger D, Rusan M, Kammerer R, Zimmermann W, Hatz R and Winter H. Chemotherapeutic induction of lymphopenia followed by reconstitution with splenocytes and active-specific tumor cell vaccination (LRAST) enhances the therapeutic efficacy against subcutaneous tumors in a mouse model of gastric cancer. J. Transl. Med. 9: 140 (2011)

Retz M, Rotering J, Nawroth R, Buchner A, Stöckle M, Gschwend J, Lehmann J. Long term follow-up of bladder cancer patients with disseminated tumor cells in bone marrow. Eur. Urol. 60: 231-8 (2011)

Schichor C, Albrecht V, Korte B, Buchner A, Riesenberg R, Mysliwietz J, Paron I, Motaln H, Tursek TL, Jürchott K, Selbig J, Tonn J-C. Mesenchymal stem cells and glioma cells form a structural as well as a functional syncytium in vitro. Exp. Neurol. 234(1): 208-19 (2011).



Bourquin C, von der Borch P, Zoglmeier C, Anz D, Sandholzer N, Wurzenberger C, Denzel A, Kammerer R, Zimmermann W, Endres S. Efficient eradication of subcutaneous but not of autochthonous gastric tumors by adoptive T cell transfer in a SV40 T antigen mouse model. J. Immunol. 185: 2580-2588 (2010)

Muenzner P, Bachmann V, Zimmermann W, Hentschel J, Hauck CR. Human-restricted bacterial pathogens block shedding of epithelial cells by stimulating integrin activation. Science 329(5996):1197-201, (2010)

Buchner A, Castro M, Hennig A, PoppT, Assmann G, Stief CG, Zimmermann W. Downregulation of HNF-1B in renal cell carcinoma is associated with tumor progression and poor prognosis. Urology 76(2):507.e6-11, (2010)

Buchner A, Pohla H, Willimsky G, Frankenberger B, Frank R, Baur-Melnyk A, Siebels M, Stief CG, Hofstetter A, Kopp J, Pezzutto A, Blankenstein T, Oberneder R, Schendel DJ. Phase I Trial of an Allogeneic Gene-modified Tumor Cell Vaccine (RCC-26/CD80/IL-2) in Patients with Metastatic Renal Cell Carcinoma. Hum. Gene Ther. 21(3): 285-97, (2010)

Kammerer R and Zimmermann W. Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen (CEA) families. BMC Biol. 8:12, (2010)

Mander A, Gouttefangeas S, Ottensmeier C, Welters MJP, Low L, van der Burgh SH, Britten CM and the ELISPOT proficiency panel: Thor Straten P, Kämpgen E, Mackensen A, Veelken H, Riemann D, Giannopoulos K, Schultz E, Pohla H, Walter S, Schmitt M, Beyer M, Paulie S, Maier R, Paschen A, Speiser D (2010). Serum is not required for ex vivo IFN-γ ELISPOT: a collaborative study of different protocols from the European CIMT Immunoguiding Program. Cancer Immunol. Immunother. 59: 619-627, (2010)

Tilki D, Singer BB, Shariat SF, Behrend A, Fernando M, Irmak S, Buchner A, Hooper AT, Stief CG, Reich O, Ergün S. CEACAM1: A novel urinary marker for bladder cancer detection. Eur. Urol. 57: 648-654, (2010)



Brill TH, Kübler HR, Pohla H, Buchner A, Fend F, Schuster T, von Randenborgh H, Paul R, Kummer T, Plank C, Eisele B, Breul J, Hartung R, Schendel DJ, Gansbacher B. Therapeutic Vaccination with an IL-2-IFNgamma-secreting Allogeneic Tumor Vaccine in Patients with Progressive Castration-Resistant Prostate Cancer - a Phase I/II Trial. Hum. Gene Ther. 20(12): 1642-51, (2009)

Wilde S, Sommermeyer D, Frankenberger B, Schiemann M, Milosevic S, Spranger S, Pohla H, Uckert W, Busch DH, Schendel DJ. Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity. Blood 114(10): 2131-9, (2009)

Geiger C, Nössner E, Frankenberger B, Falk CS, Pohla H, Schendel DJ. Harnessing innate and adaptive immunity for adoptive cell therapy of renal cell carcinoma. J. Mol. Med. 87(6): 595-612, (2009)

Herbst A, Bommer GT, Kriegl L, Jung A, Behrens A, Csanadi E, Gerhard M, Bolz C, Riesenberg R, Zimmermann W, Dietmaier W, Wolf I, Brabletz T, Göke B, Kolligs FT. ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition. Gastroenterology 137(2): 639-48, (2009)



Slevogt H, Zabel S, Opitz B, Hocke A, Eitel J, N'guessan PD, Lucka L, Riesbeck K, Zimmermann W, Zweigner J, Temmesfeld-Wollbrueck B, Suttorp N, Singer BB. CEACAM1 inhibits Toll-like receptor 2-triggered antibacterial responses of human pulmonary epithelial cells. Nat. Immunol. 9(11): 1270-8, (2008)

Kutscher S, Dembek CJ, Allgayer S, Heltai S, Stadlbauer B, Biswas P, Nozza S, Tambussi G, Bogner JR, Stellbrink HJ, Goebel FD, Lusso P, Tinelli M, Poli G, Erfle V, Pohla H, Malnati M, Cosma A. The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT. AIDS Res. Ther. 5: 22-34, (2008)

Ebelt K, Babaryka G, Figel AM, Pohla H, Buchner A, Stief CG, Eisenmenger W, Kirchner T, Schendel DJ, Noessner E. Dominance of CD4+ lymphocytic infiltrates with disturbed effector cell characteristics in the tumor microenvironment of prostate carcinoma. Prostate 68: 1-10, (2008)



Riesenberg R, Weiler C, Spring O, Eder M, Buchner A, Popp T, Castro M, Kammerer R, TakikawaO, Hatz R, Stief CG, Hofstetter A, Zimmermann W. Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long term survival of renal cell carcinoma patients. Clin. Cancer Res. 13(23): 6993-7002, (2007)

Kammerer R, Popp T, Hartle S, Singer BB, Zimmermann W. Species-specific evolution of immune receptor tyrosine based activation motif-containing CEACAM1-related immune receptors in the dog. BMC Evol. Biol. 7:196, (2007)

Rüttinger D, van den Engeln NK, Winter H, Schlemmer M, Pohla H, Grutzner S, Wagner B, Schendel DJ, Fox BA, Jauch K-W, Hatz, RA. Adjuvant therapeutic vaccination in patients with non-small cell lung cancer made lymphopenic and reconstituted with autologous PBMC: first clinical experience and evidence of an immune response. J. Transl. Med. 5: 43-56, (2007)

Brill TH, Kübler HR, v. Randenborgh H, Fend F, Pohla H, Breul J, Hartung R, Paul R, Schendel DJ, Gansbacher, B. Allogeneic retrovirally transduced, IL-2- and IFN-gamma-secreting cancer cell vaccine in patients with hormone refractory prostate cancer - a phase I clinical trial. J. Gene Med. 9: 547-60, (2007)

Zobywalski A, Javorovic M, Frankenberger B, Pohla H, Kremmer E, Bigalke I, Schendel DJ. Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70. J. Transl. Med.  5: 18-33, (2007)

Frankenberger B, Pohla H, Buchner A, Schendel DJ. Grundlagen der Immunantwort gegen das Nierenzellkarzinom und zellbasierte Vakzinetherapien. in: Neue Therapieansätze beim metastasierten Nierenzellkarzinom (Hrsg. M. Siebels, C.G. Stief, UNI-MED Bremen-London-Boston, 89-99, (2007)

Hofmann T, Buchner A, Hofstetter A, Stief CG, Oberneder R, Riesenberg R. Prognostic relevance of disseminated tumor cells in bone marrow of patients with transitional cell carcinoma. Eur. J. Cancer 43: 2678-2684, (2007)

Brämswig KH, Knittelfelder R, Gruber S, Untersmayr E, Riemer AB, Szalai K, Horvat R, Kammerer R, Zimmermann W, Zielinski CC, Scheiner O, Jensen-Jarolim E. Immunization with Mimotopes Prevents Growth of Carcinoembryonic Antigen Positive Tumors in BALB/c Mice. Clin. Cancer Res. 13: 6501-6508, (2007)

Buchner A, Castro M, Hennig A, Popp T, Assmann G, Hofstetter A, Stief C, Zimmermann W. Transcriptome analyses in renal cell carcinoma : Combination of laser microdissection and microarrays. Urologe 46: 1170-1175, (2007)



Skubitz KM, Zimmermann W, Kammerer R, Pambuccian S, Skubitz APN. Differential gene expression identifies subgroups of renal cell cancer. J. Lab. Clin. Med. 147: 250-267, (2006)

Buchner A, Riesenberg R, Kotter I, Hofstetter A, Stief CG, Oberneder R. Frequency and prognostic relevance of disseminated tumor cells in bone marrow of patients with metastasized renal cell carcinoma. Cancer 106: 1514-1520, (2006)

Rüttinger D, Winter H, van den Engel NK, Hatz RA, Schlemmer M, Pohla H, Grützner S, Schendel DJ, Fox BA, Jauch K-W. Immunotherapy of lung cancer: an update. Onkologie 29: 33-38, (2006)

Nockel J, van den Engel NK, Winter H, Hatz RA, Zimmermann W, Kammerer R. Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEA transgene. BMC Cancer 6: 57 (2006)

Schleypen JS, Baur N, Rohrmann K, Kammerer R, Schendel DJ, Pohla H, Falk CS, Noessner E. Cytotoxic markers and frequency predict functional capacity of natural killer cells infiltrating renal cell carcinoma. Clin. Cancer Res. 12: 718-725, (2006)



Poznanovic S, Wozny W, Schwall G, Sastri C, Hunzinger C, Stegmann W, Schrattenholz A, Buchner A, Gangnus R, Burgemeister R, Cahill M. Differential radioactive proteomic analysis of microdissected renal cell carcinoma tissue by 54 cm isoelectric focusing in serial immobilized pH gradient gels. J. Proteome Res. 4: 2117-2125, (2005)

Frankenberger B, Pohla H, Noessner E, Willimsky G, Papier B, Pezzutto A, Kopp K, Oberneder R, Blankenstein T, and Schendel DJ. Influence of CD80, IL-2 and IL-7 expression in human renal cell carcinoma on the expansion, function and survival of tumor-specific cytotoxic T lymphocytes. Clin. Cancer Res. 11: 1733-1742, (2005)

Javorovic M, Pohla H, Frankenberger B, Wölfel T, and Schendel DJ. RNA Transfer by electroporation into mature dendritic cells leading to reactivation of effector-memory cytotoxic T lymphocytes: A quantitative analysis. Mol. Ther. 12: 734-43, (2005)

Frankenberger B, Regn S, Geiger C, Noessner E, Falk CS, Pohla H, Javorovic M, Silberzahn T, Wilde S, Buchner A, Siebels M, Oberneder R, Willimsky G, Pezzutto A, Blankenstein T, Schendel DS. Cell-based vaccines for renal cell carcinoma: Genetically-engineered tumor cells and monocyte-derived dendritic cells. World J. Urol. 23: 166-174, (2005)

Schmetzer O, Moldenhauer G, Riesenberg R, Pires JR, Schlag P, Pezzutto A. Quality of recombinant protein determines the amount of autoreactivity detected against the tumor-associated Epithelial Cell Adhesion Molecule antigen: low frequency of antibodies against the natural protein. J. Immunol. 174: 942-952, (2005)

Singer BB, Klaile E, Scheffrahn I, Müller MM, Kammerer R, Reutter W, Öbrink B, Lucka L. CEACAM1 (CD66a) mediates delay of spontaneous and Fas ligand-induced apoptosis in granulocytes. Eur. J. Immunol. 35: 1949-1959, (2005)

McLellan AS, Fischer B, Dveksler G, Hori T, Wynne F, Ball M, Okumura K, Moore T, Zimmermann W. Structure and evolution of the mouse pregnancy-specific glycoprotein (Psg) gene locus. BMC Genomics 6: 4, (2005)

McLellan AS, Zimmermann W, Moore T. Conservation of pregnancy-specific glycoprotein (PSG) N-domains following independent expansions of the gene families in the mouse and human. BMC Evol. Biol. 5: 39, (2005)

Zebhauser R, Kammerer R, Eisenried A, McLellan A, Moore T, Zimmermann W. Identification of a novel group of evolutionary conserved members within the rapidly diverging murine Cea family. Genomics, 86: 566-580, (2005)



Kammerer R, Riesenberg R, Weiler C, Lohrmann J, Schleypen J, Zimmermann W. The tumor suppressor gene CEACAM1 is completely but reversibly down-regulated in renal cell carcinoma. J. Pathol. 204: 258-267, (2004)

Markel G, Gruda R, Achdout H, Katz G, Nechema M, Blumberg RS, Kammerer R, Zimmermann W, Mandelboim O. The critical role of residues 43R and 44Q of CEACAM1 in the protection from killing by human NK cells. J. Immunol. 173: 3732-3739, (2004)

Finkenzeller G, Weindel K, Zimmermann W, Westin G, Marmé D. Activated Neu/ErbB-2 induces expression of the vascular endothelial growth factor gene by functional activation of the transcription factor Sp1. Angiogenesis 7: 59-68, (2004)

Kammerer R, Popp T, Singer BB, Schlender J, Zimmermann W. Identification of allelic variants of the bovine immune regulatory molecule CEACAM1 implies a pathogen driven evolution. Gene 339: 99-109, (2004)

Schendel DJ, Falk C, Frankenberger B, Noessner E, Pohla H. The cellular and molecilar basis of natural anti-tumor immune responses in renal cell carcinoma patients. Urologe A 43 (suppl. 3): 133-135, (2004)



Muders M, Ghoreschi K, Suckfüll M, Zimmermann W, Enders G. Studies on the immuno¬genicity of hCEA in a transgenic mouse model. Int. J. Colorectal Dis. 18: 153-159, (2003)

McCaw SE, Schneider J, Zimmermann W, Liao, EH, Gray-Owen, SD. Immunoreceptor tyro¬sine-based activation motif (ITAM) phosphorylation during engulfment of Neisseria gonorrhoeae by the neutrophil-restricted CEACAM3 (CD66d) receptor. Mol. Microbiol. 49: 623-637, (2003)

Wahl U, Nobetaner E, Kronenberger K, Gangnus R, Pohla H, Staege MS, Kolb HJ, Hallek M, Mocikat R. Vaccination against B-cell chronic lymphocytic leukemia with trioma cells: preclini­cal evaluation. Clin. Cancer Res. 15: 4240-4246, (2003)

Buchner A, Riesenberg R, Kotter I, Hofstetter A, Crispin A, Oberneder R. Detection and prognostic value of cytokeratin positive tumor cells in bone marrow of renal cell carcinoma patients. J. Urol. 170(5): 1747-1751, (2003)

Schleypen J, von Geldern M, Weiß EH, Kotzias N, Rohrmann K, Schendel DJ, Falk CS, Pohla H. Renal cell carcinoma infiltrating natural killer cells express differential repertoires of activating and inhibitory receptors and are inhibited by specific HLA class I allotypes. Int. J. Cancer 106(6): 905-912, (2003)

Hofmann T, Riesenberg R, Buchner A, Zimmermann W, Hofstetter A, Oberneder R. Disseminated tumor cells in bone marrow of patients with transitional cell carcinoma: Immunocytochemical detection and correlation with established prognostic indicators. J. Urol. 169(4): 1303-1307, (2003)

Zigeuner R, Riesenberg R, Pohla H, Hofstetter A, Oberneder R. Isolation of circulating cancer cells from full blood by immunomagnetic cell enrichment (ICE) and immunocytochemistry in vitro. J. Urol. 169(2): 701-705, (2003)

Finkenzeller D, Fischer B, Lutz S, Schrewe H, Shimizu T, Zimmermann W. Carcinoembryonic antigen-related cell adhesion molecule 10 (CEACAM10) expressed specifically early in pregnancy in the decidua is dispensable for normal murine development. Mol. Cell. Biol. 23(1): 272-279, (2003)