PRONIA-STUDIE

PRONIA "Personalized Prognostic Tools for Early Psychosis Management" is a research project funded by the European Union to significantly improving the early detection of psychotic illness. The project aims to produce an easily accessible prognostic service for early illness detection. This forecasting system will use clinical information, cognitive data, neuroimaging, and DNA, RNA, and metabolomics.

PRONIA is comprised by a professional, motivated, and international team who develop computer models that can assess the risk of psychosis development, illness outcomes, and a range of other critical diagnostic and prognostic endpoints. In the future, these procedures will help doctors and psychologists to better assess and treat the course of the disease. For more information on this project, see PRONIA.

Contact

Phone: 089/4400-55866

PRONIA early detection

Hospital of the University of Munich

Clinic for Psychiatry and Psychotherapy

Nussbaumstraße 7

80336 Munich

 

 


PNKT-STUDIE

 

PNKT "Personalized neuro-cognitive training in depression and psychosis (high risk)" is a project in which researchers are working on the development of personalized neuro-cognitive therapies based on an individualized stratification of the risk for psychosis and a reduced functional level.

In addition to the typical symptoms of affective and non-affective psychosis, affected patients regularly suffer from cognitive impairments. Deficits in cognitive abilities in patients with psychosis are closely related to their quality of life and therefore represent a special focus in the rehabilitation of those affected. To date, it has been shown that computer-assisted neuro-cognitive training can be successfully used to reduce these cognitive deficits and at the same time improve the psychosocial function level of patients. However, previous studies show that only subpopulation of these patients offers a satisfactory response to cognitive training. One aim of the study is, therefore, to predict the positive response to this measure in order to offer cognitive training to those patients who will most likely benefit from it.

In the PNKT study, patients participate in a detailed clinical, neuro-cognitive, and imaging survey, followed by several weeks of computer-assisted cognitive training. Participation in the study ends with a follow-up examination. On the basis of multivariate pattern analyses, it is hoped that it will be possible to determine which data patterns are best for predicting whether and under what conditions a patient will benefit from cognitive training.

Contact

Phone: 089/440053447

E-mail: Shalaila.Haas@med.uni-muenchen.de

PRONIA early detection

PNKT Study

Hospital of the University of Munich

Clinic for Psychiatry and Psychotherapy

Nussbaumstraße 7

80336 Munich

 


CIP-STUDIE

CIP - Cannabis-induced psychosis - is a DFG-funded study aiming to identifying individuals with cannabis-induced psychosis at an early stage and, in the context of a longitudinal imaging study, to find out in which affected individuals the psychotic symptoms remit spontaneously after abstinence and which patients are likely to develop a permanent form of psychosis.

Recent studies have shown that up to 50% of all patients with cannabis-induced psychosis develop a form of psychosis in the long term. Thus, patients with cannabis-induced psychosis represent the population with the highest known risk of permanent forms of psychosis. However, the neurobiological fundamentals of the connection between psychosis and cannabis use have hardly been understood so far. Nevertheless, this is urgently needed in order to identify the individuals with an increased risk of psychosis already at an early stage and to prevent the development of the disease and to positively influence the course of the disease.

In the CIP study, patients with cannabis-induced psychosis are tested for baseline and follow-up after 9 months by clinical and neuropsychological tests, as well as by using structural, functional and molecular imaging. The data is then evaluated by multivariate pattern analysis to identify brain patterns associated with clinical and neuropsychological variables.

Contact

Phone: 089/440055866

E-mail: nora.penzel@med.uni-muenchen.de 

PRONIA early detection

CIP study

Hospital of the University of Munich

Clinic for Psychiatry and Psychotherapy

Nussbaumstraße 7

80336 Munich

 


TYPIA-STUDIE

TYPIA is a DFG-funded bicentric study conducted at the University of Bonn and the LMU Hospital in Munich. The aim of the study is to find out why not all people with highly pronounced schizotypic personality traits develop psychosis and the factors that protect against the development of psychosis. The project is based on observations of that suggest a continuum of psychosis symptoms between the individuals with no symptoms and populations of patients with psychosis.

Within the framework of TYPIA, test persons with high positive or negative schizotypic characteristics, control subjects with low schizotypic characteristics, and patients suffering from psychosis for the first time in the last three years are examined. The age range for all groups is between 18 and 40 years. The participation includes examinations of personality, cognition, DNA, a clinical interview, as well as images of brain structure and function using magnetic resonance imaging (MRI).

If you are interested in participating in the TYPIA study, we would be pleased if you could take about 5 minutes to complete the personality questionnaire on our homepage

If you meet our inclusion criteria, we will contact you promptly by e-mail. Your data will only be used for scientific purposes and will not be passed on to third parties. Expenditure allowance and travel expenses will be reimbursed.

Contact:

Maria F. Urquijo

Telefon:  +49(0)89/ 4400 55610

E-Mail:    typia.muenchen@gmail.com / maria.urquijo@med.uni-muenchen.de

PRONIA early detection

TYPIA study

Hospital of the University of Munich

Clinic for Psychiatry and Psychotherapy

Nussbaumstraße 7

80336 Munich