Anne Ruef

    Psychologist, Data Scientist


Research Focus

As a neuroscientist trainee, my research focus has been to integrate multimodal data to improve models predictive of psychiatric patients’ prognosis. The range of data used goes from genetic to behavioral data with a particular expertise and interest in the investigation of relevant Brain Imaging features for prediction. As part of the Neurodiagnostic lab, I’m currently involved in combining data from different research consortium, especially my work focuses on data harmonisation, quality control management as well as the development of new brain imaging pipelines all essential for to develop accurate predictive models. Ultimately, my work aims to facilitate data transfer for direct model development for clinical research


  1. Maillard AM, Ruef A*, Pizzagalli F, Migliavacca E, Hippolyte L, Adaszewski S, Dukart J, Ferrari C, Conus P, Männik K, Zazhytska M, Siffredi V, Maeder P, Kutalik Z, Kherif F, Hadjikhani N; Beckmann JS, Reymond A, Draganski B, Jacquemont S; 16p11 2 European Consortium (2015). The 16p11.2 locus modulates brain structures common to autism, schizophrenia and obesity. Molecular Psychiatry. (* Shared first authorship).

  2. Ruef A, Curtis L, Moy G, Bessero S, Ba M B, Lazeyras F, Lovblad K-O, Haller S, Malafosse A, Giannakopoulos P and Merlo M (2012). Magnetic resonance imaging correlates of first-episode psychosis in young adult male patients: combined analysis of grey and white matter. Journal of Psychiatry & Neuroscience 

  3. Popovic D, Ruef A, Dwyer DB, Antonucci LA, Eder J, Sanfelici R, Kambeitz-Ilankovic L, Faruk Oztuerk O, Dong MS, Paul R, Paolini M, Hedderich D, Haidl T, Kambeitz J, Ruhrmann S, Chisholm K, Schultze-Lutter F, Falkai P, Pergola G, Blasi G, Bertolino A, Lencer R, Dannlowski U, Upthegrove U, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Koutsouleris N , PRONIA Consortium (2020). Traces of Trauma: A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes. Biological Psychiatry

  4. Koutsouleris N, Kambeitz-Ilankovic L, Ruhrmann S, Rosen M, Ruef A, Dwyer DB, Paolini M, Chisholm K, Kambeitz J, Haidl T, Schmidt A, Gillam J, Schultze-Lutter F, Falkai P, Reiser M, Riecher-Rössler A, Upthegrove R, Hietala J, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Beque D, Brambilla P, Borgwardt S; PRONIA Consortium. (2018) Prediction Models of Functional Outcomes for Individuals in the Clinical High-Risk State for Psychosis or With Recent-Onset Depression: A Multimodal, Multisite Machine Learning Analysis. JAMA Psychiatry

  5. Lorio S, Kherif F, Ruef A, Melie-Garcia L, Frackowiak R, Ashburner J, Helms G, Lutti A, Draganski B (2016). Neurobiological origin of spurious brain morphological changes: A quantitative MRI study. Hum Brain Mapp.


Telephone: 089/440055757


Neurodiagnostic Applications

Hospital of the University of Munich
Clinic for Psychiatry and Psychotherapy

Nussbaumstraße 7
80336 München