Our Team

Teresa Kauke is one of the HLA lab-directors of the European Federation for Immunogenetics (EFI) in Munich. Teresa’s special interest is to provide optimal access of immunological risk patients to transplantation.

This year Tanja Herrler won the Eurotransplant Henk Schippers Award 2011 for her work on the prevention of renal ischemia reperfusion injury by microcapsulotomy .For the detection of pivotal long-term outcome following kidney injury she has established a preclinical monitoring model for long-term follow-up examination of renal function. Moreover, Tanja has found that increased tissue pressure due to postischemic inflammatory edema plays an important pathophysiological role in the development of kidney dysfunction after ischemia-reperfusion injury and that surgical pressure relief preserves organ structure and function.

Joachim Andrassy is the fellow of our hepatobiliary & transplant team. He won the award of the American Society of Transplantation 2004 for his research on mTOR-inhibitors in a murine tumor-transplant model. In the field of transplant immunology Joachim could substantially contribute to the current knowledge of “non-inherited maternal antigens” and their tolerogenic effect on allografts (Andrassy et al., JI 2003, JI 2007, AJT 2008).

Markus Guba has achieved a major impact in the field of de novo malignancies after transplantation and the antitumoral and antiangiogenic effects of mTOR-inhibitors (Guba et al. Nature Medicine 2002). Markus is working together with Stephan Huber on targeting HCC stem cells. Together with Antje Habicht he examines the role of immune senescence for the development of post transplant malignancies.

Andrej Khandoga studies the microvascular mechanisms of hepatic ischemia-reperfusion injury. In resent works, he has described for the first time the migration of T cells in the postischemic hepatic microcirculation in vivo and demonstrated a crucial role of the CD4+ T cell interactions with platelets as well as with Kupfer cells for liver damage and inflammation upon I/R (Khandoga et al Hepatology 2006, Hanschen et al Transplantation 2008).

Markus Rentsch and Michael Thomas currently work on Glutathion-dependent intracellular signal transduction mechanisms leading to cell protection after hepatic ischemia and reperfusion, as well as in liver regeneration after extended liver resection.

Our team of academic surgeons is supported by the technical assistance of Anne Wagner,  Sandra Derr and Nina Schupp.
Dr. Aivars Kalnins from Riga, Latvia, is currently doing a postdoctoral research fellowship in our laboratory.
Maurice Pradella, Julian Koch, Viviane Lin and Moritz Drefs are successfully working on the experiments for their doctoral thesis.

We closely collaborate with Dr. med. Antje Habicht (Transplant Center Munich) Bechara Mfarry on immune senescence after transplantation, with our radiology (PD. Dr. Nicolauou, Dr. Notohamiprodjo) and nuclear medicine department (PD Dr. Hacker) for small animal MRIs, CT-scans and scintigraphy. Teresa’s HLA lab further collaborates with the HLA lab in Essen, Germany (Prof. Dr. med. Peter Horn, Dr. Falko Heinemann) on the relevance of complement-fixing antibodies in kidney transplantation.

We welcome students, doctorates and researchers to work with us in this fascinating field of medicine!

Markus Guba
(Team leader)