Publikationen experimentelle Forschung

van den Engel NK, Rüttinger D, Rusan M, Kammerer R, Zimmermann W, Hatz RA, Winter H. Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer.
J Transl Med. 2011, 9:140

Winter H, van den Engel NK, Rusan M, Schupp N, Poehlein CH, Hu HM, Hatz RA, Urba WJ, Jauch KW, Fox BA, Rüttinger D. Active-specific immunotherapy for non-small cell lung cancer.
J Thorac Dis. 2011 Jun;3(2):105-14

Fox BA, Schendel DJ, …Winter H, et al. Defining the Critical Hurdles in Cancer Immunotherapy.
J Transl Med. 2011 9(1):214

Rüttinger D, van den Engel NK, Winter H, Schlemmer M, Pohla H, Grützner S, Wagner B, Schendel DJ, Fox BA, Jauch KW, Hatz RA. Adjuvant therapeutic vaccination in patients with non-small cell lung cancer made lymphopenic and reconstituted with autologous PBMC: first clinical experience and evidence of an immune response.
J Transl Med. 2007, 5:43

Winter H, van den Engel NK, Rüttinger D, Schmidt J, Schiller M, Poehlein CH, Lohe F, Fox BA, Jauch KW, Hatz RA, Hu HM. Therapeutic T cells induce tumor-directed chemotaxis of innate immune cells through tumor-specific secretion of chemokines and stimulation of B16BL6 melanoma to secrete chemokines.
J Transl Med.2007, 5:56

Winter H, van den Engel NK, Poehlein CH, Hatz RA, Fox BA, Hu HM. Tumor-specific T cells signal tumor destruction via the lymphotoxin beta receptor.
J Transl Med. 2007, 5:14

N.K. van den Engel, H. Winter, D. Ruttinger, I. Shau, M. Schiller, B. Mayer, T. Moudgil, G. Meimarakis, M. Stolte, K.-W. Jauch, B.A. Fox, R.A. Hatz. Characterization of immune responses in gastric cancer patients: A possible impact of H. pylori to polarize a tumor-specific type 1 response? Clin.
Immunol. 2006, 120: 285-296

J. Nöckel, N.K. van den Engel, H. Winter, R.A. Hatz, W. Zimmermann, R. Kammerer. Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEA transgene.
BMC Cancer 2006, 6:57

Meimarakis G, Winter H, Assmann I, Kopp R, Lehn N, Kist M, Stolte M, Jauch KW, Hatz RA.Helicobacter pylori as a prognostic indicator after curative resection of gastric carcinoma: a prospective study.
Lancet Oncol. 2006, 7:211-22


Publikationen klinische Forschung

Meimarakis G, Spelsberg F, Angele M, Preissler G, Fertmann J, Crispin A, Reu S, Kalaitzis N, Stemmler M, Giessen C, Heinemann V, Stintzing S, Hatz R, Winter H. Resection of pulmonary metastases from colon and rectal cancer: factors to predict survival differ regarding to the origin of the primary tumor.
Ann Surg Oncol. 2014 Aug;21(8):2563-72

Winter H, Fox BA, Rüttinger D. Future of cancer vaccines. Methods Mol Biol. 2014;1139:555-64.

Meimarakis G, Rüttinger D, Stemmler J, Crispin A, Weidenhagen R, Angele M, Fertmann J, Hatz RA, Winter H. Prolonged overall survival after pulmonary metastasectomy in patients with breast cancer.
Ann Thorac Surg. 2013 Apr;95(4):1170-80.

Meimarakis G, Angele M, Conrad C, Schauer R, Weidenhagen R, Crispin A, Giessen C, Preissler G, Wiedemann M, Jauch KW, Heinemann V, Stintzing S, Hatz RA, Winter H. Combined resection of colorectal hepatic-pulmonary metastases shows improved outcome over chemotherapy alone.
Langenbecks Arch Surg. 2013 Jan 13.

Evaluation of a new prognostic score (Munich score) to predict long-term survival after resection of pulmonary renal cell carcinoma metastases.Meimarakis G, Angele M, Staehler M, Clevert DA, Crispin A, Rüttinger D, Löhe F, Preissler G, Hatz RA, Winter H.
Am J Surg. 2011 Aug;202(2):158-67.

Impact of systematic lymph node dissection in the resection of pulmonary metastases of solid extrapulmonary tumoursMeimarakis G, Angele MK, Schneider C, Weidenhagen R, Kalaitzis N, Molki A, Jauch KW, Hatz R, Winter H.
Zentralbl Chir. 2010 Dec;135(6):556-63. Epub 2010 Nov 8. Review. German.

Vascular targeting by EndoTAG-1 enhances therapeutic efficacy of conventional chemotherapy in lung and pancreatic cancer. Eichhorn ME, Ischenko I, Luedemann S, Strieth S, Papyan A, Werner A, Bohnenkamp H, Guenzi E, Preissler G, Michaelis U, Jauch KW, Bruns CJ, Dellian M.
Int J Cancer 2010; 126: 1235-1245.

Tumor infiltrated hilar and mediastinal lymph nodes are an independent prognostic factor for decreased survival after pulmonary metastasectomy in patients with renal cell carcinoma.Winter H, Meimarakis G, Angele MK, Hummel M, Staehler M, Hoffmann RT, Hatz RA, Löhe F.
J Urol. 2010 Nov;184(5):1888-94. Epub 2010 Sep 17.

Does surgical resection of pulmonary metastases of head and neck cancer improve survival?Winter H, Meimarakis G, Hoffmann G, Hummel M, Rüttinger D, Zilbauer A, Stelter K, Spelsberg F, Jauch KW, Hatz R, Löhe F.
Ann Surg Oncol. 2008 Oct;15(10):2915-26. Epub 2008 Jul 22.

Predictors of general complications after video-assisted thoracoscopic surgical procedures.Winter H, Meimarakis G, Pirker M, Spelsberg F, Kopp R, Rüttinger D, Loehe F, Jauch KW, Hatz R.
Surg Endosc. 2008 Mar;22(3):640-5.