Startseite » Forschung » Publikationen

Publikationen

Aldinger F, Schulze TG (2017).
Environmental factors, life events, and trauma in the course of bipolar disorder.
Psychiatry Clin Neurosci. 71(1): 6-17

Budde M, Degner D, Brockmöller J, Schulze TG (2017).
Pharmacogenomic aspects of bipolar disorder: An update.
Eur Neuropsychopharmacol 2017 Mar 22. doi: 10.1016/j.euroneuro.2017.02.001

Budde M, Forstner AJ, Adorjan K, Schaupp SK, Nöthen MM, Schulze TG (2017).
Genetische Grundlagen der bipolaren Störung.
Nervenarzt. 2017 May 4. doi: 10.1007/s00115-017-0336-9

Bigdeli TB, Ripke S, Peterson RE, Trzaskowski M, Bacanu SA, Abdellaoui A, Andlauer TF, Beekman AT, Berger K, Blackwood DH, Boomsma DI, Breen G, Buttenschøn HN, Byrne EM, Cichon S, Clarke TK, Couvy-Duchesne B, Craddock N, de Geus EJ, Degenhardt F, Dunn EC, Edwards AC, Fanous AH, Forstner AJ, Frank J, Gill M, Gordon SD, Grabe HJ, Hamilton SP, Hardiman O, Hayward C, Heath AC, Henders AK, Herms S, Hickie IB, Hoffmann P, Homuth G, Hottenga JJ, Ising M, Jansen R, Kloiber S, Knowles JA, Lang M, Li QS, Lucae S, MacIntyre DJ, Madden PA, Martin NG, McGrath PJ, McGuffin P, McIntosh AM, Medland SE, Mehta D, Middeldorp CM, Milaneschi Y, Montgomery GW, Mors O, Müller-Myhsok B, Nauck M, Nyholt DR, Nöthen MM, Owen MJ, Penninx BW, Pergadia ML, Perlis RH, Peyrot WJ, Porteous DJ, Potash JB, Rice JP, Rietschel M, Riley BP, Rivera M, Schoevers R, Schulze TG, Shi J, Shyn SI, Smit JH, Smoller JW, Streit F, Strohmaier J, Teumer A, Treutlein J, Van der Auwera S, van Grootheest G, van Hemert AM, Völzke H, Webb BT, Weissman MM, Wellmann J, Willemsen G, Witt SH, Levinson DF, Lewis CM, Wray NR, Flint J, Sullivan PF, Kendler KS (2017).
Genetic effects influencing risk for major depressive disorder in China and Europe.
Transl Psychiatry 7(3):e1074

Chang H, Hoshina N, Zhang C, Ma Y, Cao H, Wang Y, Wu DD, Bergen SE, Landén M, Hultman CM, Preisig M, Kutalik Z, Castelao E, Grigoroiu-Serbanescu M, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Schofield PR, Cichon S, Nöthen MM, Swedish Bipolar Study Group, MooDS Bipolar Consortium, Walter H, Erk S, Heinz A, Amin N, van Duijn CM, Meyer-Lindenberg A, Tost H, Xiao X, Yamamoto T, Rietschel M, Li M (2017).
The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders.
Mol Psychiatry 10.1038/mp.2016.231

Chang H, Li L, Peng T, Grigoroiu-Serbanescu M, Bergen SE, Landén M, Hultman CM, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Cichon S, Nöthen MM, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Rietschel M, Swedish Bipolar Study Group, MooDS Consortium, Xiao X, Li M (2016).
Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1.
Mol Neurobiol 10.1007/s12035-016-0041-x

Forstner AJ, Hecker J, Hofmann A, Maaser A, Reinbold CS, Mühleisen TW, Leber M, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Schumacher J, Streit F, Meier S, Herms S, Hoffmann P, Lacour A, Witt SH, Reif A, Müller-Myhsok B, Lucae S, Maier W, Schwarz M, Vedder H, Kammerer-Ciernioch J, Pfennig A, Bauer M, Hautzinger M, Moebus S, Schenk LM, Fischer SB, Sivalingam S, Czerski PM, Hauser J, Lissowska J, Szeszenia-Dabrowska N, Brennan P, McKay JD, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG, Krasnov V, Chuchalin A, Babadjanova G, Pantelejeva G, Abramova LI, Tiganov AS, Polonikov A, Khusnutdinova E, Alda M, Cruceanu C, Rouleau GA, Turecki G, Laprise C, Rivas F, Mayoral F, Kogevinas M, Grigoroiu-Serbanescu M, Becker T, Schulze TG, Rietschel M, Cichon S, Fier H, Nöthen MM (2017).
Identification of shared risk loci and pathways for bipolar disorder and schizophrenia.
PLoS One 12(2):e0171595

García-González J, Tansey KE, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Žagar T, Czerski PM, Jerman B, Buttenschøn HN, Schulze TG, Zobel A, Farmer A, Aitchison KJ, Craig I, McGuffin P, Giupponi M, Perroud N, Bondolfi G, Evans D, O'Donovan M, Peters TJ, Wendland JR, Lewis G, Kapur S, Perlis R, Arolt V, Domschke K; Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium., Breen G, Curtis C, Sang-Hyuk L, Kan C, Newhouse S, Patel H, Baune BT, Uher R, Lewis CM, Fabbri C (2017).
Pharmacogenetics of antidepressant response: A polygenic approach.
Prog Neuropsychopharmacol Biol Psychiatry 75:128-134

McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium.; Schizophrenia Working Group of the Psychiatric Genomics Consortium.
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.
Nat Commun 8:14774

Zeng Y, Navarro P, Shirali M, Howard DM, Adams MJ, Hall LS, Clarke TK, Thomson PA, Smith BH, Murray A, Padmanabhan S, Hayward C, Boutin T, MacIntyre DJ, Lewis CM, Wray NR, Mehta D, Penninx BW, Milaneschi Y, Baune BT, Air T, Hottenga JJ, Mbarek H, Castelao E, Pistis G, Schulze TG, Streit F, Forstner AJ, Byrne EM, Martin NG, Breen G, Müller-Myhsok B, Lucae S, Kloiber S, Domenici E; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium., Deary IJ, Porteous DJ, Haley CS, McIntosh AM (2017).
Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder.
Biol Psychiatry doi: 10.1016/j.biopsych.2016.12.012. [Epub ahead of print]

CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium; Psychosis Endophenotypes International Consortium (2017).
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.
Nat Genet 49(1): 27-35

Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DH, Boomsma D, Breen G, Buttenschøn HN, Byrne EM, Børglum AD, Castelao E, Cichon S, Clarke TK, Cornelis MC, Dannlowski U, De Jager PL, Demirkan A, Domenici E, van Duijn CM, Dunn EC, Eriksson JG, Esko T, Faul JD, Ferrucci L, Fornage M, de Geus E, Gill M, Gordon SD, Grabe HJ, van Grootheest G, Hamilton SP, Hartman CA, Heath AC, Hek K, Hofman A, Homuth G, Horn C, Jan Hottenga J, Kardia SL, Kloiber S, Koenen K, Kutalik Z, Ladwig KH, Lahti J, Levinson DF, Lewis CM, Lewis G, Li QS, Llewellyn DJ, Lucae S, Lunetta KL, MacIntyre DJ, Madden P, Martin NG, McIntosh AM, Metspalu A, Milaneschi Y, Montgomery GW, Mors O, Mosley THJ, Murabito JM, Müller-Myhsok B, Nöthen MM, Nyholt DR, O'Donovan MC, Penninx BW, Pergadia ML, Perlis R, Potash JB, Preisig M, Purcell SM, Quiroz JA, Räikkönen K, Rice JP, Rietschel M, Rivera M, Schulze TG, Shi J, Shyn S, Sinnamon GC, Smit JH, Smoller JW, Snieder H, Tanaka T, Tansey KE, Teumer A, Uher R, Umbricht D, Van der Auwera S, Ware EB, Weir DR, Weissman MM, Willemsen G, Yang J, Zhao W, Tiemeier H, Sullivan PF (2016).
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
Biol Psychiatry 10.1016/j.biopsych.2016.11.013

Bauer M, Banaschewski T, Heinz A, Kamp-Becker I, Meyer-Lindenberg A, Padberg F, Rapp MA, Rupprecht R, Schneider F, Schulze TG, Wittchen H-U (2016).
Das deutsche Forschungsnetz zu psychischen Erkrankungen.
Nervenarzt 87(9): 989-1010

Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, Werge T, Blackwood DH, Pato CN, Pato MT, Malhotra AK, O'Donovan MC, Kendler KS, Fanous AH; Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016).
Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.
Am J Med Genet B Neuropsychiatr Genet 171B(2): 276-89

Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJ, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, Andreassen OA, Gruber O, Sachdev PS, Roiz-Santiañez R, Saykin AJ, Ehrlich S, Mather KA, Turner JA, Schwarz E, Thalamuthu A, Yao Y, Ho YY, Martin NG, Wright MJ; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Psychosis Endophenotypes International Consortium; Wellcome Trust Case Control Consortium 2; Enigma Consortium, O'Donovan MC, Thompson PM, Neale BM, Medland SE, Sullivan PF (2016).
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.
Nat Neurosci 19(3): 420-31

Geoffroy PA, Etain B, Lajnef M, Zerdazi EH, Brichant-Petitjean C, Heilbronner U, Hou L, Degenhardt F, Rietschel M, McMahon FJ, Schulze TG, Jamain S, Marie-Claire C, Bellivier F (2016).
Circadian genes and lithium response in bipolar disorders:Associations with PPARGC1A (PGC-1α) and RORA.
Genes Brain Behav 15(7): 660-8

Gill KE, Cardenas SA, Kassem L, Schulze TG, McMahon FJ (2016).
Symptom profiles and illness course among Anabaptist and Non-Anabaptist adults with major mood disorders.
Int J Bipolar Disord 4(1): 21

Gould TD, Hashimoto R, Schulze TG (2016).
Going longitudinal in biological psychiatric research: All things considered.
Neurosci Res 102: 1-3

Heilbronner U, Gade K, Herms S, Strohmaier J, Lang M, Nöthen MM, Rietschel M, Schulze TG, Degenhardt F (2016).
Effect of copy number variant burden on Global Assessment of Functioning in schizophrenia.
Psychiatr Genet 26(4): 184-5

Heilbronner U, Samara M, Leucht S, Falkai P, Schulze TG (2016).
The Longitudinal Course of Schizophrenia Across the Lifespan: Clinical, Cognitive, and Neurobiological Aspects.
Harv Rev Psychiatry 24(2): 118-28

Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landén M, Adli M, Alda M, Ardau R, Arias B, Aubry JM, Backlund L, Badner JA, Barrett TB, Bauer M, Baune BT, Bellivier F, Benabarre A, Bengesser S, Berrettini WH, Bhattacharjee AK, Biernacka JM, Birner A, Bloss CS, Brichant-Petitjean C, Bui ET, Byerley W, Cervantes P, Chillotti C, Cichon S, Colom F, Coryell W, Craig DW, Cruceanu C, Czerski PM, Davis T, Dayer A, Degenhardt F, Del Zompo M, DePaulo JR, Edenberg HJ, Étain B, Falkai P, Foroud T, Forstner AJ, Frisén L, Frye MA, Fullerton JM, Gard S, Garnham JS, Gershon ES, Goes FS, Greenwood TA, Grigoroiu-Serbanescu M, Hauser J, Heilbronner U, Heilmann-Heimbach S, Herms S, Hipolito M, Hitturlingappa S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kelsoe JR, Kittel-Schneider S, Kliwicki S, Koller DL, König B, Lackner N, Laje G, Lang M, Lavebratt C, Lawson WB, Leboyer M, Leckband SG, Liu C, Maaser A, Mahon PB, Maier W, Maj M, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, McInnis MG, McKinney R, Mitchell PB, Mitjans M, Mondimore FM, Monteleone P, Mühleisen TW, Nievergelt CM, Nöthen MM, Novák T, Nurnberger JIJ, Nwulia EA, Ösby U, Pfennig A, Potash JB, Propping P, Reif A, Reininghaus E, Rice J, Rietschel M, Rouleau GA, Rybakowski JK, Schalling M, Scheftner WA, Schofield PR, Schork NJ, Schulze TG, Schumacher J, Schweizer BW, Severino G, Shekhtman T, Shilling PD, Simhandl C, Slaney CM, Smith EN, Squassina A, Stamm T, Stopkova P, Streit F, Strohmaier J, Szelinger S, Tighe SK, Tortorella A, Turecki G, Vieta E, Volkert J, Witt SH, Wright A, Zandi PP, Zhang P, Zollner S, McMahon FJ (2016).
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.
Hum Mol Genet 25(15): 3383-3394

Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CEM, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Brichant-Petitjean C, Bui ET, Cervantes P, Chen GB, Chen HC, Chillotti C, Cichon S, Clark SR, Colom F, Cousins DA, Cruceanu C, Czerski PM, Dantas CB, Dayer A, Étain B, Falkai P, Forstner AJ, Frisén L, Fullerton JM, Gard S, Garnham JS, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Lackner N, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, López Jaramillo CA, MacQueen G, Manchia M, Martinsson L, Mattheisen M, McCarthy MJ, McElroy SL, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Ösby U, Ozaki N, Perlis RE, Pfennig A, Reich-Erkelenz D, Rouleau GA, Schofield PR, Schubert KO, Schweizer BW, Seemüller F, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Smoller JW, Squassina A, Stamm T, Stopkova P, Tighe SK, Tortorella A, Turecki G, Volkert J, Witt S, Wright A, Young LT, Zandi PP, Potash JB, DePaulo JR, Bauer M, Reininghaus EZ, Novák T, Aubry JM, Maj M, Baune BT, Mitchell PB, Vieta E, Frye MA, Rybakowski JK, Kuo PH, Kato T, Grigoroiu-Serbanescu M, Reif A, Del Zompo M, Bellivier F, Schalling M, Wray NR, Kelsoe JR, Alda M, Rietschel M, McMahon FJ, Schulze TG (2016).
Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.
Lancet 387(10023): 1085-93

Johnson EC, Bjelland DW, Howrigan DP, Abdellaoui A, Breen G, Borglum A, Cichon S, Degenhardt F, Forstner AJ, Frank J, Genovese G, Heilmann-Heimbach S, Herms S, Hoffman P, Maier W, Mattheisen M, Morris D, Mowry B, Müller-Mhysok B, Neale B, Nenadic I, Nöthen MM, O'Dushlaine C, Rietschel M, Ruderfer DM, Rujescu D, Schulze TG, Simonson MA, Stahl E, Strohmaier J, Witt SH, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Sullivan PF, Keller MC (2016).
No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study.
PLoS Genet 12(10): e1006343

Lang FU, Müller-Stierlin AS, Walther S, Schulze TG, Becker T, Jäger M (2016).
Psychopathological Symptoms Assessed by a System-Specific Approach Are Related to Global Functioning in Schizophrenic Disorders.
Psychopathology 49(2): 77-82

Li M, Luo XJ, Landén M, Bergen SE, Hultman CM, Li X, Zhang W, Yao YG, Zhang C, Liu J, Mattheisen M, Cichon S, Mühleisen TW, Degenhardt FA, Nöthen MM, Schulze TG, Grigoroiu-Serbanescu M, Li H, Fuller CK, Chen C, Dong Q, Chen C, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Preisig M, Kutalik Z, Castelao E, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG, MooDS Consortium, Swedish Bipolar Study Group, Rietschel M, Liu C, Kleinman JE, Hyde TM, Weinberger DR, Su B (2016).
Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance.
Br J Psychiatry 208(2): 128-37

Liu C, Saffen D, Schulze TG, Burmeister M, Sham PC, Yao YG, Kuo PH, Chen C, An Y, Dai J, Yue W, Li MX, Xue H, Su B, Chen L, Shi Y, Qiao M, Liu T, Xia K, Chan RC (2016).
Psychiatric genetics in China: achievements and challenges.
Mol Psychiatry 21(1): 4-9

Papiol S, Fatjó-Vilas M, Schulze TG (2016).
Neurological soft signs in patients with schizophrenia: current knowledge and future perspectives in the post-genomics era.
Transl Dev Psychiatry 4: 30071

Reich-Erkelenz D, Schmitt A, Falkai P (2016).
Stepping up: the just released new impact factor 2015.
Eur Arch Psychiatry Clin Neurosci, DOI 10.1007/s00406-016-0714-5

Reta Y, Tesfaye M, Girma E, Dehning S, Adorjan K (2016).
Public Stigma against People with Mental Illness in Jimma Town, Southwest Ethiopia.
PLoS One 11(11): e0163103

Ritter P, S., Bermpohl F, Gruber O, Hautzinger M, Jansen A, Juckel G, Kircher T, Lambert M, Mulert C, Pfennig A, Reif A, Rienhoff O, Schulze TG, Severus E, Stamm T, Bauer M (2016).
Aims and structure of the German Research Consortium BipoLife for the study of bipolar disorder.
Int J Bipolar Disord 4(1): 26

Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Daly MJ, Carroll MC, Stevens B, McCarroll SA (2016).
Schizophrenia risk from complex variation of complement component 4.
Nature 530(7589): 177-83

Van der Auwera S, Teumer A, Hertel J, Homuth G, Völker U, Lucht MJ, Degenhardt F, Schulze TG, Rietschel M, Nöthen MM, John U, Nauck M, Grabe HJ (2016).
The inverse link between genetic risk for schizophrenia and migraine through NMDA (N-methyl-D-aspartate) receptor activation via D-serine.
Eur Neuropsychopharmacol 26(9): 1507-15

Vázquez-Bourgon J, Roiz-Santiañez R, Papiol S, Ferro A, Varela-Gómez N, Fañanás L, Crespo-Facorro B (2016).
Variations in Disrupted-in-Schizophrenia 1 gene modulate long-term longitudinal differences in cortical thickness in patients with a first-episode of psychosis. Brain Imaging Behav 10(3): 629-35

Wigand ME, Lang FU, Becker T, Schulze TG, Strik W, Jäger M (2016).
Psychopathological course typology in schizophrenia spectrum disorders: a heuristic approach in a sample of 100 patients.
Psychopathology 49(6): 397-405

Zai G, Alberry B, Arloth J, Bánlaki Z, Bares C, Boot E, Camilo C, Chadha K, Chen Q, Cole CB, Cost KT, Crow M, Ekpor I, Fischer SB, Flatau L, Gagliano S, Kirli U, Kukshal P, Labrie V, Lang M, Lett TA, Maffioletti E, Maier R, Mihaljevic M, Mittal K, Monson ET, O'Brien NL, Østergaard SD, Ovenden E, Patel S, Peterson RE, Pouget JG, Rovaris DL, Seaman L, Shankarappa B, Tsetsos F, Vereczkei A, Wang C, Xulu K, Yuen RK, Zhao J, Zai CC, Kennedy JL (2016).
Rapporteur summaries of plenary, symposia, and oral sessions from the XXIIIrd World Congress of Psychiatric Genetics Meeting in Toronto, Canada, 16-20 October 2015.
Psychiatr Genet 26(6): 229-257

Ament SA, Szelinger S, Glusman G, Ashworth J, Hou L, Akula N, Shekhtman T, Badner JA, Brunkow ME, Mauldin DE, Stittrich AB, Rouleau K, Detera-Wadleigh SD, Nurnberger JI Jr, Edenberg HJ, Gershon ES, Schork N; Bipolar Genome Study, Price ND, Gelinas R, Hood L, Craig D, McMahon FJ, Kelsoe JR, Roach JC.
Rare variants in neuronal excitability genes influence risk for bipolar disorder.
Proc Natl Acad Sci U S A 2015 112(11): 3576-81

Anand A, Koller DL, Lawson WB, Gershon ES, Nurnberger JI; BiGS Collaborative.
Genetic and childhood trauma interaction effect on age of onset in bipolar disorder: An exploratory analysis.
J Affect Disord 2015 179: 1-5. Epub 2015 Mar 10

Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Conley ED; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC), Ruepp A, Müller-Myhsok B, Hariri AR, Binder EB; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC.
Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders.
Neuron. 2015 Jun 3;86(5):1189-202

Falkai P, Rossner MJ, Schulze TG, Hasan A, Brzózka MM, Malchow B, Honer WG, Schmitt A.
Kraepelin revisited: schizophrenia from degeneration to failed regeneration.
Mol Psychiatry 2015 20(6): 671-6

Forstner AJ, Hofmann A, Maaser A, Sumer S, Khudayberdiev S, Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Schumacher J, Breuer R, Meier S, Herms S, Hoffmann P, Lacour A, Witt SH, Reif A, Müller-Myhsok B, Lucae S, Maier W, Schwarz M, Vedder H, Kammerer-Ciernioch J, Pfennig A, Bauer M, Hautzinger M, Moebus S, Priebe L, Sivalingam S, Verhaert A, Schulz H, Czerski PM, Hauser J, Lissowska J, Szeszenia-Dabrowska N, Brennan P, McKay JD, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG, Krasnov V, Chuchalin A, Babadjanova G, Pantelejeva G, Abramova LI, Tiganov AS, Polonikov A, Khusnutdinova E, Alda M, Cruceanu C, Rouleau GA, Turecki G, Laprise C, Rivas F, Mayoral F, Kogevinas M, Grigoroiu-Serbanescu M, Propping P, Becker T, Rietschel M, Cichon S, Schratt G, Nöthen MM.
Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder.
Transl Psychiatry 2015 5: e678

Fullerton JM, Koller DL, Edenberg HJ, Foroud T, Liu H, Glowinski AL, McInnis MG, Wilcox HC, Frankland A, Roberts G, Schofield PR, Mitchell PB, Nurnberger JI; Bipolar High Risk Study Group, BiGS Consortium.
Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals.
Am J Med Genet B Neuropsychiatr Genet. 2015 Oct;168(7):617-29. doi: 10.1002/ajmg.b.32344. Epub 2015 Jul 16

Gade K, Malzahn D, Anderson-Schmidt H, Strohmaier J, Meier S, Frank J, Falkai PG, Rietschel M, Schulze TG.
Functional outcome in major psychiatric disorders and associated clinical and psychosocial variables: A potential cross-diagnostic phenotype for further genetic investigations?
World J Biol Psychiatry 2015 16(4): 237-48. Epub 2015 Mar 14

Gould TD, Hashimoto R, Schulze TG.
Going longitudinal in biological psychiatric research: All things considered.
Neurosci Res 2015 Dec 29. pii: S0168-0102(15)00303-X. doi: 10.1016/j.neures.2015.12.012

Großimlinghaus I, Falkai P, Gaebel W, Hasan A, Jänner M, Janssen B, Reich-Erkelenz D, Grüber L, Böttcher V, Wobrock T, Zielasek J, LVR-Klinikverbund.
Erhebung von Qualitätsindikatoren anhand von Routinedaten.
Nervenarzt 2015, DOI 10.1007/s00115-015-4357-y

Heilbronner U, Malzahn D, Strohmaier J, Maier S, Frank J, Treutlein J, Mühleisen TW, Forstner AJ, Witt SH, Cichon S, Falkai P, Nöthen MM, Rietschel M, Schulze TG (2015).
A common risk variant in CACNA1C supports a sex-dependent effect on longitudinal functioning and functional recovery from episodes of schizophrenia-spectrum but not bipolar disorder.
Eur Neuropsychopharmacol 25(12): 2262-70

Heilbronner U, Hinrichs H, Heinze HJ, Zaehle T.
Caffeine differentially alters cortical hemodynamic activity during working memory: a near infrared spectroscopy study.
BMC Res Notes 2015 8: 520

Heilbronner U, Malzahn D, Strohmaier J, Maier S, Frank J, Treutlein J, Mühleisen TW, Forstner AJ, Witt SH, Cichon S, Falkai P, Nöthen MM, Rietschel M, Schulze TG (2015).
A common risk variant in CACNA1C supports a sex-dependent effect on longitudinal functioning and functional recovery from episodes of schizophrenia-spectrum but not bipolar disorder.
Eur Neuropsychopharmacol 25(12): 2262-70

Lang FU, Walther S, Stegmayer K, Anderson-Schmidt H, Schulze TG, Becker T, Jäger M.
Subtyping schizophrenia: A comparison of positive/negative and system-specific approaches.
Compr Psychiatry 2015 61: 115-21

Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, Price AL, O'Donovan M, Okada Y, Mowry BJ, Raychaudhuri S, Wray NR; Schizophrenia Working Group of the Psychiatric Genomics Consortium and Rheumatoid Arthritis Consortium International; Schizophrenia Working Group of the Psychiatric Genomics Consortium authors, Byerley W, Cahn W, Cantor RM, Cichon S, Cormican P, Curtis D, Djurovic S, Escott-Price V, Gejman PV, Georgieva L, Giegling I, Hansen TF, Ingason A, Kim Y, Konte B, Lee PH, McIntosh A, McQuillin A, Morris DW, Nöthen MM, O'Dushlaine C, Olincy A, Olsen L, Pato CN, Pato MT, Pickard BS, Posthuma D, Rasmussen HB, Rietschel M, Rujescu D, Schulze TG, Silverman JM, Thirumalai S, Werge T; Schizophrenia Working Group of the Psychiatric Genomics Consortium collaborators, Agartz I, Amin F, Azevedo MH, Bass N, Black DW, Blackwood DH, Bruggeman R, Buccola NG, Choudhury K, Cloninger RC, Corvin A, Craddock N, Daly MJ, Datta S, Donohoe GJ, Duan J, Dudbridge F, Fanous A, Freedman R, Freimer NB, Friedl M, Gill M, Gurling H, De Haan L, Hamshere ML, Hartmann AM, Holmans PA, Kahn RS, Keller MC, Kenny E, Kirov GK, Krabbendam L, Krasucki R, Lawrence J, Lencz T, Levinson DF, Lieberman JA, Lin DY, Linszen DH, Magnusson PK, Maier W, Malhotra AK, Mattheisen M, Mattingsdal M, McCarroll SA, Medeiros H, Melle I, Milanova V, Myin-Germeys I, Neale BM, Ophoff RA, Owen MJ, Pimm J, Purcell SM, Puri V, Quested DJ, Rossin L, Ruderfer D, Sanders AR, Shi J, Sklar P, St Clair D, Scott Stroup T, Van Os J, Visscher PM, Wiersma D, Zammit S; Rheumatoid Arthritis Consortium International authors, Louis Bridges S Jr, Choi HK, Coenen MJ, de Vries N, Dieud P, Greenberg JD, Huizinga TW, Padyukov L, Siminovitch KA, Tak PP, Worthington J; Rheumatoid Arthritis Consortium International collaborators, De Jager PL, Denny JC, Gregersen PK, Klareskog L, Mariette X, Plenge RM, van Laar M, van Riel P (2015).
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.
Int J Epidemiol 44(5): 1706-21

Li M, Huang L, Grigoroiu-Serbanescu M, Bergen SE, Landén M, Hultman CM, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Cichon S, Nöthen MM, Alkelai A, Lerer B, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Rietschel M; MooDS Consortium; Swedish Bipolar Study Group (2016).
Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis.
Mol Neurobiol 53(10):6608-19

Luo XJ, Mattheisen M, Li M, Huang L, Rietschel M, Børglum AD, Als TD, van den Oord EJ, Aberg KA, Mors O, Mortensen PB, Luo Z, Degenhardt F, Cichon S, Schulze TG, Nöthen MM; iPSYCH-GEMS SCZ working group; MooDS SCZ Consortium, Su B, Zhao Z, Gan L, Yao YG (2015).
Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function.
Schizophr Bull 41(6): 1294-308
Malchow B, Keller K, Hasan A, Dörfler S, Schneider-Axmann T, Hillmer-Vogel U, Honer WG, Schulze TG, Niklas A, Wobrock T, Schmitt A, Falkai P.
Effects of Endurance Training Combined With Cognitive Remediation on Everyday Functioning, Symptoms, and Cognition in Multiepisode Schizophrenia Patients.
Schizophr Bull. 2015 41(4): 847-58. Epub 2015 Mar 17

Malchow B, Strocka S, Frank F, Bernstein HG, Steiner J, Schneider-Axmann T, Hasan A, Reich-Erkelenz D, Schmitz C, Bogerts B, Falkai P, Schmitt A.
Stereological investigation of the posterior hippocampus in affective disorder.
J Neural Transm. 2015 Jul; 122(7): 1019-33. Epub 2014 Oct 12.

Milanesi E, Hadar A, Maffioletti E, Werner H, Shomron N, Gennarelli M, Schulze TG, Costa M, Del Zompo M, Squassina A, Gurwitz D.
Insulin-like Growth Factor 1 Differentially Affects Lithium Sensitivity of Lymphoblastoid Cell Lines from Lithium Responder and Non-responder Bipolar Disorder Patients.
J Mol Neurosci. 2015 Jul;56(3):681-7. doi: 10.1007/s12031-015-0523-8. Epub 2015 Mar 5

Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJ, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S; Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium (Corporate Collaborator), Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J; Social Science Genetic Association Consortium Corporate Collaborator, Willemsen G, Zhu Z, Boomsma DI, Wray NR, Penninx BW; Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium Corporate Collaborator; Social Science Genetic Association Consortium Corporate Collaborator.
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.
Mol Psychiatry. 2015 Jun;20(6):735-43. doi: 10.1038/mp.2015.50. Epub 2015 Apr 28

Reich-Erkelenz D, Schmitt A, Falkai P.
Unravelling basic mechanisms in addiction and neuropsychiatric disorders.
Eur Arch Psychiatry Clin Neurosci 2015 265(8): 633-5

Reich-Erkelenz D, Schmitt A, Falkai P.
Genetic and environmental risk factors in neurodevelopmental disorders.
Eur Arch Psychiatry Clin Neurosci 2015 265(6): 445-7

Reich-Erkelenz D, Schmitt A, Falkai P.
Psychiatrists' self-stigma, the DGPPN guideline for psychosocial interventions, and contemporary treatment strategies.
Eur Arch Psychiatry Clin Neurosci 2015 265(3): 171-2

Swaminathan S, Koller DL, Foroud T, Edenberg HJ, Xuei X, Niculescu AB 3rd; Bipolar Genome Study (BiGS) Consortium,, Nurnberger JI Jr.
Characteristics of Bipolar I patients grouped by externalizing disorders.
J Affect Disord. 2015 Jun 1;178:206-14. doi: 10.1016/j.jad.2015.03.011. Epub 2015 Mar 14

Tighe SK, Ritchey M, Schweizer B, Goes FS, MacKinnon D, Mondimore F, Raymond DePaulo J, McMahon FJ, Schulze TG, Zandi PP, Potash JB.
Test-retest reliability of a new questionnaire for the retrospective assessment of long-term lithium use in bipolar disorder.
J Affect Disord 2015 174: 589-93. Epub 2014 Nov 24

Vázquez-Bourgon J, Roiz-Santiañez R, Papiol S, Ferro A, Varela-Gómez N, Fañanás L, Crespo-Facorro B.
Variations in Disrupted-in-Schizophrenia 1 gene modulate long-term longitudinal differences in cortical thickness in patients with a first-episode of psychosis.

Brain Imaging and Behavior 2015: pp 1-7; Epub 2015 Jul 26

Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A,Lindström S, Ripke S, Genovese G, Loh P-R, Bhatia G, Do R, Hayeck T, Won H-H, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study, Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL.
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
Am J Hum Genet 2015: 97(4):576-92

Badowska DM, Reich‑Erkelenz D, Schmitt A, Falkai P.
Pathways to personalized treatment strategies for depressive
disorders
.
Eur Arch Psychiatry Clin Neurosci (2015) 265:1–3

Budde M, Schulze TG.
Neurocognitive correlates of the course of bipolar disorder.
Harv Rev Psychiatry 2014 22(6): 342-7

Reich-Erkelenz D, Schmitt A, Falkai P.
New aspects of cognition domains and psychopathological measures in psychiatry.
Eur Arch Psychiatry Clin Neurosci. 2014 Dec;264(8):647-9

Malchow B1, Strocka S, Frank F, Bernstein HG, Steiner J, Schneider-Axmann T, Hasan A, Reich-Erkelenz D, Schmitz C, Bogerts B, Falkai P, Schmitt A.

 
DE EN