News

Role of Vascular Factors in Migraine

22.06.2016 - A Genome-wide association study with involvement of ISD investigators has identified 38 susceptibility loci for migraine including 28 novel loci. The results lend further weight to a vascular etiology of migraine and emphasize genetic overlap with stroke [more...]

 

New Program on Stroke and Dementia

09.05.2016 - New EU-funded project CoSTREAM targets the common mechanisms and pathways of stroke, Alzheimer’s disease to improve disease prevention and treatment, by combining clinical, genetic, epidemiologic, metabolic and radiologic research to develop an organ-on-a-chip in vitro model for the blood-brain co... [more...]

 

Novel risk loci for large and small vessel stroke

14.04.2016 - In a series of genome-wide association studies (GWAS) ISD investigators in collaboration with other scientists from the international stroke genetics consortium (ISGC) recently identified several risk loci for ischemic stroke. The work is published in three papers in Lancet Neurology and Neurology [more...]

 

TREM2 in prodromal AD

03.02.2016 - Mutations in the TREM2 gene are associated with a threefold risk of AD dementia. A multicenter study led by M. Ewers (ISD) & C. Haass (DZNE) suggests that soluble TREM2 in cerebrospinal fluid is a novel biomarker of neurofinflammation, altered early in sporadic AD. [more...]

 

New Network on Small Vessel Diseases

01.01.2016 - ISD investigators engaged into a 5-year collaborative program to uncover common mechanisms and pathways in different forms of cerebral small vessel disease. The new network (SVDs@target) involves in... [more...]

Role of pericytes in CADASIL

08.10.2015 - A study by Ghosh and colleagues (Plesnila lab) published in the Annals of Neurology demonstrates that pericytes are critically involved in the initiation of CADASIL, an inherited small vessel diseas... [more...]

 

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