Remote cortical effects after ischemic stroke

01.04.2015 - Remote effects of infarcts are considered determinants of stroke outcome. This study demonstrates loss of both white and grey matter in distant brain regions connected to infarcts, suggesting secondary neurodegeneration as a key mechanism underlying remote changes after stroke. [more...]


Hannelore Kohl Foundation Award

09.03.2015 - Dr. Nicole Terpolilli, a clinician scientist working in the Laboratory of Experimental Stroke Research (Prof. N. Plesnila) received the prestigious 2014 Hannelore Kohl Foundation Award for her publication on the use of inhaled nitric oxide (NO) for the treatment of traumatic brain injury. [more...]


Cysteine-sparing NOTCH3 mutations

21.01.2015 - The role of cysteine-sparing NOTCH3 mutations in CADASIL has been debated for a long time. Using single-particle analysis ISD investigators now demonstrated enhanced aggregation behavior similar to typical cysteine mutations. Their work published in the STROKE journal has implications for di [more...]


Multi-national EU grant awarded to ISD

22.10.2014 - Ali Ertürk and Nikolaus Plesnila were awarded a multi-national grant from Era-Net Neuron. Consortium (CnsAflame) partners from Germany, Sweden, France, and Israel will try to unravel the role of neuroi [more...]

Alarmins in brain-immune communication

15.01.2015 - A new study by A. Liesz and colleagues identifies alarmins, in particular HMGB1, as key mediators of the complex peripheral immune alterations after stroke. Alarmins are released from necrotic brain ti [more...]




Prof. Dr. med. Martin Dichgans

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Centrum für Schlaganfall- und Demenzforschung

CSD at a glance...

Cluster of Excellence