Institute for Stroke and Dementia Research (ISD)
EU funded project on Cerebral Small Vessel Disease
Investigators from Munich, Paris, and Graz have engaged in a joint project to tackle the mechanisms of cerebral small vessel disease and how small vessel-related brain lesions cause cognitive decline. The project is funded by the ERA-NET NEURON (joint call 2011).
New susceptibility locus for atherosclerotic stroke
A recent genome-wide association study in patients with ischemic stroke demonstrates that common variants in the histone deacetylase 9 gene are associated with atherosclerotic stroke. The discovery originates from a collaborative effort involving ISD investigators.
Inhaled nitric oxide for the treatment of stroke
A study from ISD’s Laboratory of Experimental Stroke Research (Prof. N. Plesnila) in press at Circulation Research shows that inhalation of nitric oxide (NO) preserves blood flow and rescues brain tissue in mice subjected to cerebral ischemia. These results may pave the way for a novel therapeutic concept for patients with ischemic strokes.
Prof. Nikolaus Plesnila and team have joined the ISD on October 1st coming from the Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland. Prof. Plesnila will establish and head the Laboratory of Experimental Stroke Research, a facility with specific expertise in the investigation of the cerebral microcirculation and in the evaluation of novel therapeutic strategies for ischemic and hemorrhagic stroke.
