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ISD opens new state-of-the-art facility for stem cell research.

The ISD research group for neurobiology – led by Prof. Dominik Paquet - opened a new stem cell research facility at the CSD building to investigate dementia, stroke and related diseases in novel human brain tissue models derived from patient stem cells... [mehr...]


The choroid plexus is a key cerebral invasion route for T cells after stroke.

ISD researchers have identified the choroid plexus as a previously unrecognized key structure for cerebral T cell invasion into the brain after stroke. These findings are of high relevance for clinical trials targeting immune cell infiltration in stroke patients... [mehr...]


Novel Risk Loci for Alzheimer's Disease

A multinational consortium including ISD researchers identified rare coding variants associated with Alzheimer's disease (AD). The variants are situated in genes that are highly expressed in microglia and highlight a role of microglia-mediated innate immune responses in AD... [mehr...]


miRNA set as a novel biomarker for ischemic stroke

Using RNA sequencing and qRT-PCR in three independent samples of acute ischemic stroke patients ISD researchers established a set of 3 circulating microRNAs (miR-125a-5p, miR-125b-5p and miR-143-3p) as a promising blood-based diagnostic marker for the early phase of ischemic stroke [mehr...]


Fritz Thyssen Foundation Award

Dr. Ali Ertürk received a competitive grant from the Fritz Thyssen Foundation awarded to young scientists working in the field of Medicine and the Natural Sciences. Dr. Ertürk will investigate the m... [mehr...]

Atheroprotective function for COP9 signalosome

Applying preclinical models of atherosclerosis and myeloid-specific gene knockout, an international team led by ISD researchers found that the deNEDDylase CSN5, a subunit of the COP9 signalosome tha... [mehr...]



Prof. Dr. med. Martin Dichgans

CSD im Überblick...

Centrum für Schlaganfall- und Demenzforschung