Publikationen 2013

  1. Akthar S, Gremse F, Kiessling F, Weber C, Schober A. CXCL12 promotes the stabilization of atherosclerotic lesions mediated by smooth muscle progenitor cells in mice. Arterioscler Thromb Vasc Biol. 2013;33:679-86. Pubmed

  2. Asare Y, Shagdarsuren E, Schmid J, Tilstam PV, Grommes J, El Bounkari O, Schütz AK, Weber C, de Winther MP, Noels H,Bernhagen J. Endothelial CSN5 impairs NF-κB activation and monocyte adhesion to endothelial cells and is highly expressed in human atherosclerotic lesions. Thromb Haemost. 2013;110:141-52. Pubmed

  3. Badr Eslam R, Lang IM, Koppensteiner R, Calatzis A, Panzer S, Gremmel T. Residual platelet activation through protease-activated receptors (PAR)-1 and -4 in patients on P2Y12 inhibitors. Int J Cardiol. 2013;168:403-6. Pubmed

  4. Borissoff JI, Otten JJ, Heeneman S, Leenders P, van Oerle R, Soehnlein O, Loubele ST, Hamulyák K, Hackeng TM, Daemen MJ, Degen JL, Weiler H, Esmon CT, van Ryn J, Biessen EA, Spronk HM, ten Cate H. Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner. PLoS One. 2013;8:e55784. Pubmed

  5. Bras G, Bochenska O, Rapala-Kozik M, Guevara-Lora I, Faussner A, Kamysz W, Kozik A. Release of biologically active kinin peptides, Met-Lys-bradykinin and Leu-Met-Lys-bradykinin from human kininogens by two major secreted aspartic proteases of Candida parapsilosis. Peptides. 2013;48C:114-123. Pubmed

  6. Casanova-Acebes M, Pitaval C, Weiss L, Nombela-Arrieta C, Chèvre R, A-González N, Kunisaki Y, Zhang D, van Rooijen N, Silberstein L, Weber C, Nagasawa T, Frenette P, Castrillo A, Hidalgo A. Rhythmic modulation of the hematopoietic niche through neutrophil clearance. Cell. 2013;153:1025-1035. Pubmed

  7. Döring Y, Weber C, Soehnlein O. Footprints of neutrophil extracellular traps as predictors of cardiovascular risk. Arterioscler Thromb Vasc Biol. 2013;33:1735-6 Pubmed

  8. Drechsler M, Soehnlein O. The complexity of arterial classical monocyte recruitment. J Innate Immun. 2013 2013;5:358-66. Pubmed

  9. Drechsler M, Soehnlein O, Weber C. Nitric oxide-donating statins upgrade the benefits of lipid-lowering in vascular inflammation by desensitizing neutrophil activation. Cardiovasc Drugs Ther. 2013;27:183-5. Pubmed

  10. Fujita B, Strodthoff D, Fritzenwanger M, Pfeil A, Ferrari M, Goebel B, Figulla HR, Gerdes N, Jung C. Altered red blood cell distribution width in overweight adolescents and its association with markers of inflammation. Pediatr Obes. 2013;8:385-91 Pubmed 

  11. Gerdes N, Winkels H, Weber C. Atherosclerosis: cell biology and lipoproteins - focus on anti-inflammatory mechanisms as therapeutic options. Curr Opin Lipidol. 2013;24:187-188. Pubmed

  12. Ghosh M, van den Akker NM, Wijnands KA, Poeze M, Weber C, McQuade LE, Pluth MD, Lippard SJ, Post MJ, Molin DG, van Zandvoort MA. Specific visualization of nitric oxide in the vasculature with two-photon microscopy using a copper based fluorescent probe. PLoS One. 2013;8:e75331. Pubmed

  13. Goyal P, Pandey D, Brünnert D, Hammer E, Zygmunt M, Siess W. Cofilin oligomer formation occurs in vivo and is regulated by cofilin phosphorylation. PLoS One. 2013;8:e71769. Pubmed

  14. Guevara-Lora I, Blonska B, Faussner A, Kozik A. Kinin-generating cellular model obtained from human glioblastoma cell line U-373. Acta Biochim Pol. 2013;60:299-305. Pubmed

  15. Heymans S, Corsten MF, Verhesen W, Carai P, van Leeuwen RE, Custers K, Peters T, Hazebroek M, Stöger L, Wijnands E, Janssen BJ, Creemers EE, Pinto YM, Grimm D, Schürmann N, Vigorito E, Thum T, Stassen F, Yin X, Mayr M, De Windt LJ, Lutgens E, Wouters K, de Winther MP, Zacchigna S, Giacca M, van Bilsen M, Papageorgiou AP, Schroen B. Macrophage microRNA-155 promotes cardiac hypertrophy and failure. Circulation. 2013;128:1420-32. Pubmed

  16. von Hundelshausen P, Weber C. Chronic inflammation and atherosclerosis Dtsch Med Wochenschr. 2013;138:1839-44 Pubmed

  17. Kanzler I, Tuchscheerer N, Steffens G, Simsekyilmaz S, Konschalla S, Kroh A, Simons D, Asare Y, Schober A, Bucala R, Weber C, Bernhagen J, Liehn EA. Differential roles of angiogenic chemokines in endothelial progenitor cell-induced angiogenesis. Basic Res Cardiol. 2013;108:310. Pubmed

  18. Karshovska E, Weber C, von Hundelshausen P. Platelet chemokines in health and disease. Thromb Haemost. 2013;110:894-902. Pubmed

  19. Klingenberg R, Gerdes N, Badeau RM, Gisterå A, Strodthoff D, Ketelhuth DF, Lundberg AM, Rudling M, Nilsson SK, Olivecrona G, Zoller S, Lohmann C, Lüscher TF, Jauhiainen M, Sparwasser T, Hansson GK. Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis. J Clin Invest. 2013;123:1323-34. Pubmed

  20. Kramp BK, Megens RT, Sarabi A, Winkler S, Projahn D, Weber C, Koenen RR, von Hundelshausen P. Exchange of extracellular domains of CCR1 and CCR5 reveals confined functions in CCL5-mediated cell recruitment. Thromb Haemost. 2013;110:795-806. Pubmed

  21. Kumar N, Ippel H, Weber C, Hackeng T, Mayo KH. Protein lysine N(zeta) alkylation and O-phosphorylation mediated by DTT-generated reactive oxygen species. Protein Sci. 2013;22:327-46. Pubmed

  22. Langer HF, Weber C, Gawaz M. The platelet - Thrombosis and Beyond. Thromb Haemost. 2013;110:857-8. Pubmed

  23. Legein B, Temmerman L, Biessen EA, Lutgens E. Inflammation and immune system interactions in atherosclerosis. Cell Mol Life Sci. 2013;70:3847-69. Pubmed

  24. Lenglet S, Thomas A, Soehnlein O, Montecucco F, Burger F, Pelli G, Galan K, Cravatt B, Staub C, Steffens S. Fatty Acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice. Arterioscler Thromb Vasc Biol. 2013;33:215-23. Pubmed

  25. Leschner J, Wennerberg G, Feierler J, Bermudez M, Welte B, Kalatskaya I, Wolber G, Faussner A. Interruption of the ionic lock in the bradykinin b2 receptor results in constitutive internalization and turns several antagonists into strong agonists. J Pharmacol Exp Ther. 2013;344:85-95. Pubmed

  26. Liehn EA, Kanzler I, Konschalla S, Kroh A, Simsekyilmaz S, Sönmez TT, Bucala R, Bernhagen J, Weber C. Compartmentalized protective and detrimental effects of endogenous migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusion. Arterioscler Thromb Vasc Biol. 2013;33:2180-6. Pubmed

  27. Lievens D, Habets KL, Robertson AK, Laouar Y, Winkels H, Rademakers T, Beckers L, Wijnands E, Boon L, Mosaheb M, Ait-Oufella H, Mallat Z, Flavell RA, Rudling M, Binder CJ, Gerdes N, Biessen EA, Weber C, Daemen MJ, Kuiper J, Lutgens E. Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis. Eur Heart J. 2013;34:3717-27. Pubmed

  28. Lundberg AM, Ketelhuth DF, Johansson ME, Gerdes N, Liu S, Yamamoto M, Akira S, Hansson GK. Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in hematopoietic cells promotes atherosclerosis. Cardiovasc Res. 2013;99:364-73. Pubmed

  29. Manthey HD, Cochain C, Barnsteiner S, Karshovska E, Pelisek J, Koch M, Chaudhari SM, Busch M, Eckstein HH, Weber C, Koenen RR, Zernecke A. CCR6 selectively promotes monocyte mediated inflammation and atherogenesis in mice. Thromb Haemost. 2013;110:1267-77. Pubmed

  30. Molica F, Burger F, Thomas A, Staub C, Tailleux A, Staels B, Pelli G, Zimmer A, Cravatt B, Matter CM, Pacher P, Steffens S. Endogenous cannabinoid receptor CB1 activation promotes vascular smooth muscle cell proliferation and neointima formation. J Lipid Res. 2013;54:1360-8. Pubmed

  31. Nakahata AM, Mayer B, Neth P, Hansen D, Sampaio MU, Oliva ML. Blocking the proliferation of human tumor cell lines by peptidase inhibitors from bauhinia seeds. Planta Med. 2013;79:227-35. Pubmed

  32. Neth P, Nazari-Jahantigh M, Schober A, Weber C. MicroRNAs in flow-dependent vascular remodeling. Cardiovasc Res. 2013;99:294-303. Pubmed 

  33. Oral H, Kanzler I, Tuchscheerer N, Curaj A, Simsekyilmaz S, Sönmez TT, Radu E, Postea O, Weber C, Schuh A, Liehn EA.CXC chemokine KC fails to induce neutrophil infiltration and neoangiogenesis in a mouse model of myocardial infarction. J Mol Cell Cardiol. 2013;60:1-7. Pubmed

  34. Ortega-Gómez A, Perretti M, Soehnlein O. Resolution of inflammation: an integrated view. EMBO Mol Med. 2013;5:661-74. Pubmed

  35. Petzold T, Ruppert R, Pandey D, Barocke V, Meyer H, Lorenz M, Zhang L, Siess W, Massberg S, Moser M. β1 integrin-mediated signals are required for platelet granule secretion and hemostasis in mouse. Blood. 2013;122:2723-31. Pubmed

  36. Potì F, Gualtieri F, Sacchi S, Weißen-Plenz G, Varga G, Brodde M, Weber C, Simoni M, Nofer JR. KRP-203, sphingosine 1-phosphate receptor type 1 agonist, ameliorates atherosclerosis in LDL-R-/- mice. Arterioscler Thromb Vasc Biol. 2013;33:1505-12. Pubmed

  37. Preissner KT, Weber C. Go with the flow: the passion for vascular biology research. Thromb Haemost. 2013;109:366-367. Pubmed

  38. Schaffer S, Tandon R, Zipse H, Siess W, Schmidt A, Jamasbi J, Karshovska E, Steglich W, Lorenz R. Stereo specific platelet inhibition by the natural LXR agonist 22(R)-OH-cholesterol and its fluorescence labelling with preserved bioactivity and chiral handling in macrophages. Biochem Pharmacol. 2013;86:279-85. Pubmed

  39. Seijkens T, Kusters P, Engel D, Lutgens E. CD40-CD40L: Linking pancreatic, adipose tissue and vascular inflammation in type 2 diabetes and its complications. Diab Vasc Dis Res. 2013;10:115-22. Pubmed

  40. Smeets E, Meiler S, Lutgens E. Lymphocytic tumor necrosis factor receptor superfamily co-stimulatory molecules in the pathogenesis of atherosclerosis. Curr Opin Lipidol. 2013;24:518-24. Pubmed
  41. Soehnlein O. Myeloid Cells in Traffic. J Innate Immun. 2013;5:301-3. Pubmed

  42. Soehnlein O, Drechsler M, Döring Y, Vijayan S, Lievens D, Hartwig H, Projahn D, Koenen RR, Hristov M, Lutgens E, Zernecke A, Weber C. Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes. EMBO Mol Med. 2013;5:471-81. Pubmed

  43. Soehnlein O, Swirski FK. Hypercholesterolemia links hematopoiesis with atherosclerosis. Trends Endocrinol Metab. 2013;24:129-36. Pubmed

  44. Strodthoff D, Lundberg AM, Agardh HE, Ketelhuth DF, Paulsson-Berne G, Arner P, Hansson GK, Gerdes N. Lack of invariant natural killer T cells affects lipid metabolism in adipose tissue of diet-induced obese mice. Arterioscler Thromb Vasc Biol. 2013;33:1189-96. Pubmed

  45. Strüßmann T, Tillmann S, Wirtz T, Bucala R, von Hundelshausen P, Bernhagen J. Platelets are a previously unrecognised source of MIF. Thromb Haemost. 2013;10:1004-13. Pubmed

  46. Vasina EM, Cauwenberghs S, Staudt M, Feijge MA, Weber C, Koenen RR, Heemskerk JW. Aging- and activation-induced platelet microparticles suppress apoptosis in monocytic cells and differentially signal to proinflammatory mediator release. Am J Blood Res. 2013;3:107-23. Pubmed.

  47. Wantha S, Alard JE, Megens RT, van der Does AM, Döring Y, Drechsler M, Pham CT, Wang MW, Wang JM, Gallo R, von Hundelshausen P, Lindbom L, Hackeng TM, Weber C, Soehnlein O. Neutrophil-derived cathelicidin promotes adhesion of classical monocytes. Circ Res. 2013;112:792-801. Pubmed

  48. Weber C. MicroRNAs - from basic mechanisms to clinical application in cardiovascular medicine. Arterioscler Thromb Vasc Biol. 2013;33:168-9. Pubmed

  49. Weber C, Lip G. Editors' Choice papers in Thrombosis and Haemostasis. Thromb. Haemost., 2013;109:170-173. Link

  50. Weber C, Lip G. A Happy New Year 2013 for Thrombosis and Haemostasis… Thromb. Haemost., 2013;109:1-2. Link

  51. Wei Y, Nazari-Jahantigh M, Chan L, Zhu M, Heyll K, Corbalán-Campos J, Hartmann P, Thiemann A, Weber C, Schober A. The microRNA-342-5p fosters inflammatory macrophage activation through an Akt1- and microRNA-155-dependent pathway during atherosclerosis. Circulation. 2013;127:1609-19. Pubmed

  52. Wei Y, Nazari-Jahantigh M, Neth P, Weber C, Schober A. MicroRNA-126, -145, and -155: A therapeutic triad in atherosclerosis? Arterioscler Thromb Vasc Biol. 2013;33:449-54. Pubmed

  53. Wei Y, Schober A, Weber C. Pathogenic arterial remodeling: the good and bad in microRNAs.  Am J Physiol Heart Circ Physiol. 2013;304:1050-9. Pubmed

  54. Wu Z, Curaj A, Fokong S, Liehn EA, Weber C, Lammers T, Kiessling F, van Zandvoort M. Rhodamine-loaded ICAM-targeted microbubbles for dual-modality imaging under controlled shear stresses. Circ Cardiovasc Imaging. 2013;6:974-81. Pubmed

  55. Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jauhiainen S, Jukema JW, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PW, Waltenberger J, Weber C, Tokgözoglu L; ESC Working Group of Atherosclerosis and Vascular Biology. Stabilization of atherosclerotic plaques: an update. Eur Heart J. 2013;34:3251-8. Pubmed

  56. Ziegler T, Horstkotte J, Schwab C, Pfetsch V, Weinmann K, Dietzel S, Rohwedder I, Hinkel R, Gross L, Lee S, Hu J, Soehnlein O, Franz WM, Sperandio M, Pohl U, Thomas M, Weber C, Augustin HG, Fässler R, Deutsch U, Kupatt C.  Ziegler T, Horstkotte J, Schwab C, Pfetsch V, Weinmann K, Dietzel S, Rohwedder I, Hinkel R, Gross L, Lee S, Hu J, Soehnlein O, Franz WM, Sperandio M, Pohl U, Thomas M, Weber C, Augustin HG, Fässler R, Deutsch U, Kupatt C.  Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis. J Clin Invest. 2013;123:3436–3445. Link

  57. Zimmermann R, Krueger J, Filipović MR, Ivanović-Burmazović I, Calatzis A, Weiss DR, Eckstein R. A detailed examination of platelet function inhibition by nitric oxide in platelet-rich plasma and whole blood. Clin Lab. 2013;59:629-38. Pubmed

 

 
 
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