| 1. |
Faussner A, Schüssler S, Feierler J, Bermudez M, Pfeifer J, Schnatbaum K, Tradler T, Jochum M, Wolber G, Gibson C. (2012) Binding characteristics of [3H]JSM10292: a new cell membrane-permeant nonpeptide bradykinin B2 receptor antagonist. Br J Pharmacol. 2012 May 30. doi: 10.1111/j.1476-5381.2012.02054.x. |
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| 2. |
Feierler J, Wirth M, Welte B, Schüssler S, Jochum M, and Faussner A. Helix 8 plays a crucial role in bradykinin B2 receptor trafficking and signaling (J. Biol. Chem., 2011 Oct 21. |
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| 3. |
Ring L, Peröbner I, Karow M, Jochum M, Neth P, Faussner A. (2011) Reporter gene HEK 293 cells and WNT-Frizzled-fusion proteins as tools to study WNT signaling pathways. Biol Chem. 392: 1011-1020; 2011 Aug 30. |
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| 4 |
Leschner J, Ring L, Feierler J, Dinkel K, Jochum M, Faussner A. (2011) Fever-like temperature modification differentially affects in vitro signaling of bradykinin B1and B2 receptors. Biol Chem. 392:1021-1029; 2011 Aug 28. |
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| 5. |
Guevara-Lora, I., Majkucinska, M. , Barbasz, A. , Faussner, A. , Kozik, A. (2011) Kinin generation from exogenous kininogens at the surface of retinoic acid-differentiated human neuroblastoma IMR-32 cells after stimulation with interferon-y.Peptides. 32(6):1193-200. Epub 2011 Apr 27. |
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| 6. |
Rapala-Kozik, M., Karkowska-Kuleta, J., Ryzanowska, A., Golda, A., Barbasz, A., Faussner, A., Kozik, A. (2010) Degradation of human kininogens with the release of kinin peptides by extracellular proteinases of Candida spp. Biol. Chem., Vol. 391(7), pp. 1193-200. |
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| 7. |
Nägler, D. K., Kraus, S., Feierler, J., Mentele, R., Lottspeich, F., Jochum, M., Faussner, A. (2010) A cysteine-type carboxypeptidase, cathepsin X, generates peptide receptor agonists. Int. Immunopharmacol. 10(1):134-9. Epub 2009 Oct 1. |
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| 8. |
Gibson, C., Schnatbaum, K., Pfeifer, J.R., Locardi, E., Paschke, M., Reimer, U., Richter, U., Scharn, D., Faussner, A., Tradler, T. (2009) Novel small molecule bradykinin B2 receptor antagonists. J. Med. Chem. 52(14):4370-9. |
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| 9. |
Faussner, A., Wennerberg, G., Schüssler, S., Feierler, J., Seidl, C., Jochum, M., Proud, D. (2009) Alanine screening of the intracellular loops of the human bradykinin B receptor--effects on receptor maintenance, G protein activation and internalization. FEBS J. 276(13):3491-503. Epub 2009 May 18. |
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| 10. |
Zubakova, R., Gille, A., Faussner, A., Hilgenfeldt, U. (2008) Ca2+ signalling of kinins in cells expressing rat, mouse and human B1/B2-receptor. Int Immunopharmacol. 2008 Feb;8(2):276-81. Epub 2007 Oct 25. |
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| 11. |
Schremmer-Danninger, E., Nägler D. K., Miska, K., Flaig M. J., Faussner, A., Fink, E., Raggi M. C., Jochum, M., Rehbock, J. (2006) Kinin receptors in stimulated and characterized decidua tissue-derived cells. Int. Immunopharmacol. 7, 103-112. Epub 2006 Oct 3. |
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| 12. |
Kalatskaya, I., Schüssler, S. Seidl, C., Jochum, M., and Faussner, A. (2006) C-terminal fusion of eGFP to the bradykinin B2 receptor strongly affects down-regulation but not receptor internalization or signaling. Biol. Chem. 387, 603-610. |
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| 13. |
Faussner, A., Bauer, A., Kalatskaya, I., Schüssler, S., Seidl, C., Proud, D., and Jochum, M. (2005) The role of the cytosolic C-termini in the internalization, signal transduction of B1 and B2 kinin receptors. FEBS Journal 272, 129-140. |
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| 14. |
Faussner, A., Schüssler, S., Seidl, C., and Jochum, M. (2004) Inhibition of B2 Bradykinin receptor sequestration by phenylarsine oxide or sucrose allows determination of receptor affinity shift and ligand dissociation in intact cells. Biol. Chem. 385, 835-843. |
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| 15. |
Kalatskaya, I., Schüssler, S., Blaukat, A., Müller-Esterl, W., Jochum, M., Proud, D., and Faussner, A. (2004) Mutation of tyrosine in the conserved NPXXY sequence leads to constitutive phosphorylation and internalization, but not signaling, of the human B2 bradykinin receptor. J. Biol. Chem. 279, 31268-31276. |
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| 16. |
Blaukat, A., Micke, P., Kalatskaya, I., Faussner, A., and Müller-Esterl, W. (2003) Down-regulation of bradykinin B2 receptor in human fibroblasts during prolonged agonist exposure. Am. J. Physiol. - Heart 284, 1909-1916. |
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| 17. |
Faussner, A., Bauer, A., Kalatskaya, I., Jochum, M., Fritz, H. (2003) Expression levels strongly affect ligand-induced sequestration of B2 bradykinin receptors in transfected cells. Am. J. Physiol. - Heart 284, 1892-1898. |
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| 18. |
Faussner, A. and Roscher, A. A. (2000) Guanosine nucleotides regulate B2 kinin receptor affinity of agonists but not of antagonists: discussion of a model proposing receptor precoupling to G protein. Biol. Chem. 381, 295-302. |
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| 19. |
Faussner, A., Proud, D., Towns, M., and Bathon, J. M. (1998). Influence of the cytosolic carboxy termini of human B1 and B2 kinin receptors on receptor sequestration and ligand internalization. J. Biol. Chem. 273, 2617-2623. |
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| 20. |
Austin, C. E., Faussner, A., Robinson, H.E., Chakravarty, S., Kyle, D. J., Bathon, J. M., and Proud, D. (1997) Stable expression of the human kinin B1 receptor in CHO cells: characterization of ligand binding and effector pathways. J. Biol. Chem. 272, 11420-11425. |
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| 21. |
Kasel, A. M., Faussner, A., Pfeifer, A., Werdan, K., Müller, U., Roscher, A. A. (1996) B2 bradkyinin receptors in cultured neonatal rat cardiomyocytes mediate a negative chronotropic and negative inotropic response. Diabetes 45, S44-S50. |
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| 22. |
Tippmer, S., Quitterer, U., Kolm, V., Faussner, A., Roscher, A. A., Mosthaf, L., Müller-Esterl, W., and Häring, H. (1994). Bradykinin induces translocation of the protein-kinase C isoforms . Eur. J. Biochem. 225, 297-304. |
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| 23. |
Faussner, A., Heinz-Erian, P., Klier, C., Roscher, A. A. (1991) Solubilization and characterization of B2 bradykinin receptors from cultured human fibroblasts. J. Biol. Chem. 266, 9442-9446. |
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Buchkapitel |
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Carlos D.Figueroa, C.D, Faussner A., Bhoola. K. (2012) Kallikrein-kinin cascade: bioregulation by human tissue kallikrein 1. Chapter for Kallikrein-related Peptidases. |
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Roscher, A. A. and Faussner, A. (1997) Cellular regulation of kinin receptors-Potential role in inflammation. Chapter for Lung Biology in Health and Disease. Pro-inflammatory and anti-inflammatory peptides. Editor Siad, S. I., Lenfant, C. |
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Proud, D., Reynolds, C. J., Bathon, J. M., and Faussner, A. (1997) Kinin actions in the human airways: modulation by allergic inflammation. Chapter for Asthma and Allergic Diseases. Physiology, Immunopharmacology and Treatment. Editors: Morone, G., Holgate, S. T., Kay, A. B., Austen, K. F., Lichtenstein, L. M. |
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