Fachgesellschaften und Leitlinien


European Neuroendocrine Tumor Society (ENETS)

ENETS-Guidelines 2016

ENETS-Guidelines 2017


Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)

S2K-Leitlinie "Neuroendokrine Tumoren"


Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF)

S2K-Leitinie “Neuroendokrine Tumoren“ 


Nuklearmedizinische Leitlinien

[Peptide receptor radionuclide therapy for patients with somatostatin receptor expressing tumours. German Guideline (S1)].
[Article in German]

Poeppel TD1, Boy C, Bockisch A, Kotzerke J, Buchmann I, Ezziddin S, Scheidhauer K, Krause BJ, Schmidt D, Amthauer H, Rösch F, Nagarajah J, Führer D, Lahner H, Pöpperl G, Hörsch D, Walter MA, Baum RP. Nuklearmedizin. 2015;54(1):1-11; quiz N2.

Leitlinien zur 68Ga-DOTA-PET/CT:

Guideline for PET/CT imaging of neuroendocrine neoplasms with 68Ga-DOTA-conjugated somatostatin receptor targeting peptides and 18F-DOPA. Bozkurt MF, Virgolini I, Balogova S, Beheshti M, Rubello D, Decristoforo C, Ambrosini V, Kjaer A, Delgado-Bolton R, Kunikowska J, Oyen WJG, Chiti A, Giammarile F, Fanti S.
Eur J Nucl Med Mol Imaging. 2017 Aug;44(9):1588-1601. doi: 10.1007/s00259-017-3728-y. Epub 2017 May 25.
PMID:28547177

Procedure guidelines for PET/CT tumour imaging with 68Ga-DOTA-conjugated peptides: 68Ga-DOTA-TOC, 68Ga-DOTA-NOC, 68Ga-DOTA-TATE. Virgolini I, Ambrosini V, Bomanji JB, Baum RP, Fanti S, Gabriel M, Papathanasiou ND, Pepe G, Oyen W, De Cristoforo C, Chiti A.
Eur J Nucl Med Mol Imaging. 2010 Oct;37(10):2004-10. doi: 10.1007/s00259-010-1512-3.
PMID:20596866


NCCN Guidelines - last update 2014:

Neuroendocrine tumors, version 1.2015.
Kulke MH, Shah MH, Benson AB 3rd, Bergsland E, Berlin JD, Blaszkowsky LS, Emerson L, Engstrom PF, Fanta P, Giordano T, Goldner WS, Halfdanarson TR, Heslin MJ, Kandeel F, Kunz PL, Kuvshinoff BW 2nd, Lieu C, Moley JF, Munene G, Pillarisetty VG, Saltz L, Sosa JA, Strosberg JR, Vauthey JN, Wolfgang C, Yao JC, Burns J, Freedman-Cass D; National comprehensive cancer network. J Natl Compr Canc Netw. 2015 Jan;13(1):78-108.


ESMO Guidelines - last update 2013:

Neuroendocrine gastro-entero-pancreatic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Öberg K, Knigge U, Kwekkeboom D, Perren A; ESMO Guidelines Working Group.

Ann Oncol. 2012 Oct;23 Suppl 7:vii124-30.

Neuroendocrine bronchial and thymic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Öberg K, Hellman P, Ferolla P, Papotti M; ESMO Guidelines Working Group.

Ann Oncol. 2012 Oct;23 Suppl 7:vii120-3.

Small-cell lung cancer (SCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Früh M, De Ruysscher D, Popat S, Crinò L, Peters S, Felip E; ESMO Guidelines Working Group.

Ann Oncol. 2013 Oct;24 Suppl 6:vi99-105. doi: 10.1093/annonc/mdt178. Epub 2013 Jun 27.

Adrenal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Berruti A1, Baudin E, Gelderblom H, Haak HR, Porpiglia F, Fassnacht M, Pentheroudakis G; ESMO Guidelines Working Group.

Ann Oncol. 2012 Oct;23 Suppl 7:vii131-8.


NANETS Guidelines

2017

The Surgical Management of Small Bowel Neuroendocrine Tumors: Consensus Guidelines of the North American Neuroendocrine Tumor Society.
Howe JR, Cardona K, Fraker DL, Kebebew E, Untch BR, Wang YZ, Law CH, Liu EH, Kim MK, Menda Y, Morse BG, Bergsland EK, Strosberg JR, Nakakura EK, Pommier RF.
Pancreas. 2017 Jul;46(6):715-731. doi: 10.1097/MPA.0000000000000846.

The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors.
Strosberg JR, Halfdanarson TR, Bellizzi AM, Chan JA, Dillon JS, Heaney AP, Kunz PL, O'Dorisio TM, Salem R, Segelov E, Howe JR, Pommier RF, Brendtro K, Bashir MA, Singh S, Soulen MC, Tang L, Zacks JS, Yao JC, Bergsland EK.
Pancreas. 2017 Jul;46(6):707-714. doi: 10.1097/MPA.0000000000000850.

2013

Consensus guidelines for the management and treatment of neuroendocrine tumors.

Kunz PL, Reidy-Lagunes D, Anthony LB, Bertino EM, Brendtro K, Chan JA, Chen H, Jensen RT, Kim MK, Klimstra DS, Kulke MH, Liu EH, Metz DC, Phan AT, Sippel RS, Strosberg JR, Yao JC; NorthAmerican Neuroendocrine Tumor Society.

Pancreas. 2013 May;42(4):557-77. doi: 10.1097/MPA.0b013e31828e34a4.

The NANETS consensus guidelines for the diagnosis and management of poorly differentiated (high-grade) extrapulmonary neuroendocrine carcinomas.

Strosberg JR, Coppola D, Klimstra DS, Phan AT, Kulke MH, Wiseman GA, Kvols LK; North American Neuroendocrine Tumor Society (NANETS).

Pancreas. 2010 Aug;39(6):799-800. doi: 10.1097/MPA.0b013e3181ebb56f.

NANETS consensus guideline for the diagnosis and management of neuroendocrine tumors: well-differentiated neuroendocrine tumors of the thorax (includes lung and thymus).

Phan AT, Oberg K, Choi J, Harrison LH Jr, Hassan MM, Strosberg JR, Krenning EP, Kocha W, Woltering EA, Maples WJ; North American Neuroendocrine Tumor Society (NANETS).

Pancreas. 2010 Aug;39(6):784-98. doi: 10.1097/MPA.0b013e3181ec1380.

The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer.

Chen H, Sippel RS, O'Dorisio MS, Vinik AI, Lloyd RV, Pacak K; North American Neuroendocrine Tumor Society (NANETS).

Pancreas. 2010 Aug;39(6):775-83. doi: 10.1097/MPA.0b013e3181ebb4f0.

The NANETS consensus guidelines for the diagnosis and management of gastrointestinal neuroendocrine tumors (nets): well-differentiated nets of the distal colon and rectum.

Anthony LB, Strosberg JR, Klimstra DS, Maples WJ, O'Dorisio TM, Warner RR, Wiseman GA, Benson AB 3rd, Pommier RF; North American Neuroendocrine Tumor Society (NANETS).

Pancreas. 2010 Aug;39(6):767-74. doi: 10.1097/MPA.0b013e3181ec1261.

The NANETS consensus guideline for the diagnosis and management of neuroendocrine tumors: well-differentiated neuroendocrine tumors of the Jejunum, Ileum, Appendix, and Cecum.

Boudreaux JP, Klimstra DS, Hassan MM, Woltering EA, Jensen RT, Goldsmith SJ, Nutting C, Bushnell DL, Caplin ME, Yao JC; North American Neuroendocrine Tumor Society (NANETS).

Pancreas. 2010 Aug;39(6):753-66. doi: 10.1097/MPA.0b013e3181ebb2a5.

NANETS treatment guidelines: well-differentiated neuroendocrine tumors of the stomach and pancreas.

Kulke MH, Anthony LB, Bushnell DL, de Herder WW, Goldsmith SJ, Klimstra DS, Marx SJ, Pasieka JL, Pommier RF, Yao JC, Jensen RT; North American Neuroendocrine Tumor Society (NANETS).

Pancreas. 2010 Aug;39(6):735-52. doi: 10.1097/MPA.0b013e3181ebb168.

NANETS consensus guidelines for the diagnosis of neuroendocrine tumor.

Vinik AI, Woltering EA, Warner RR, Caplin M, O'Dorisio TM, Wiseman GA, Coppola D, Go VL; North American Neuroendocrine Tumor Society (NANETS).

Pancreas. 2010 Aug;39(6):713-34. doi: 10.1097/MPA.0b013e3181ebaffd. No abstract available.

The North American Neuroendocrine Tumor Society (NANETS) guidelines: mission, goals, and process.

Kvols LK, Brendtro KL; North American Neuroendocrine Tumor Society (NANETS).

Pancreas. 2010 Aug;39(6):705-6. doi: 10.1097/MPA.0b013e3181eb7451. No abstract available.


Clinical Practice Guidelines for Multiple Endocrine Neoplasia Type 1 (MEN1)

Clinical Practice Guidelines for Multiple Endocrine Neoplasia Type 1 (MEN1).

Rajesh V Thakker, Paul J Newey, Gerard V Walls, John Bilezikian, Henning Dralle, Peter R Ebeling, Shlomo Melmed, Akihiro Sakurai, Francesco Tonelli, and Maria Luisa Brandi J Clin Endocrinol Metab 2012, 10.1210/jc.2012-1230

The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours.
Zaknun JJ, Bodei L, Mueller-Brand J, Pavel ME, Baum RP, Hörsch D, O'Dorisio MS, O'Dorisiol TM, Howe JR, Cremonesi M, Kwekkeboom DJ. Eur J Nucl Med Mol Imaging. 2013 May;40(5):800-16. doi: 10.1007/s00259-012-2330-6.

Procedure guidelines for PET/CT tumour imaging with 68Ga-DOTA-conjugated peptides: 68Ga-DOTA-TOC, 68Ga-DOTA-NOC, 68Ga-DOTA-TATE.
Virgolini I, Ambrosini V, Bomanji JB, Baum RP, Fanti S, Gabriel M, Papathanasiou ND, Pepe G, Oyen W, De Cristoforo C, Chiti A. Eur J Nucl Med Mol Imaging. 2010 Oct;37(10):2004-10. doi: 10.1007/s00259-010-1512-3.


AACE Endocrine Surgery Scientific Committee Leitlinien

Aace/Ace disease state clinical review: pancreatic neuroendocrine incidentalomas.
Herrera MF, Åkerström G, Angelos P, Grant CS, Hoff AO, Pantoja JP, Pérez-Johnston R, Sahani DV, Wong RJ, Randolph G.
Endocr Pract. 2015 May;21(5):546-53. doi: 10.4158/EP14465.DSC.

Aace/Ace disease state clinical review: diagnosis and management of midgut carcinoids.
Liu EH, Solorzano CC, Katznelson L, Vinik AI, Wong R, Randolph G; AACE Endocrine Surgery Scientific Committee AACE Endocrine Surgery Scientific Committee – Neuroendocrine Carcinoid Subgroup.
Endocr Pract. 2015 May;21(5):534-45. doi: 10.4158/EP14464.DSC.


Nordic Guidelines - last update 2014:

Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrineneoplasms.

Janson ET, Sorbye H, Welin S, Federspiel B, Grønbæk H, Hellman P, Ladekarl M, Langer SW, Mortensen J, Schalin-Jäntti C, Sundin A, Sundlöv A, Thiis-Evensen E, Knigge U.

Acta Oncol. 2014 Aug 20:1-14. [Epub ahead of print]

Nordic Guidelines 2010 for diagnosis and treatment of gastroenteropancreatic neuroendocrinetumours.

Janson ET, Sørbye H, Welin S, Federspiel B, Grønbaek H, Hellman P, Mathisen O, Mortensen J, Sundin A, Thiis-Evensen E, Välimäki MJ, Oberg K, Knigge U.

Acta Oncol. 2010 Aug;49(6):740-56. doi: 10.3109/0284186X.2010.492791. Review.


UK Guidelines - last update 2012:

Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs).

Ramage JK, Ahmed A, Ardill J, Bax N, Breen DJ, Caplin ME, Corrie P, Davar J, Davies AH, Lewington V, Meyer T, Newell-Price J, Poston G, Reed N, Rockall A, Steward W, Thakker RV, Toubanakis C, Valle J, Verbeke C, Grossman AB; UK and Ireland Neuroendocrine Tumour Society.

Gut. 2012 Jan;61(1):6-32. doi: 10.1136/gutjnl-2011-300831. Epub 2011 Nov 3.


Spanish  Guidelines - last update 2014:

SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic neuroendocrineneoplasms (GEP-NENs) 2014.

Garcia-Carbonero R, JImenez-Fonseca P, Teulé A, Barriuso J, Sevilla I.

Clin Transl Oncol. 2014 Sep 3. [Epub ahead of print]

SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic neuroendocrinetumours (GEP NETS).

García-Carbonero R, Salazar R, Sevilla I, Isla D.

Clin Transl Oncol. 2011 Aug;13(8):545-51. doi: 10.1007/s12094-011-0695-9.


Canadian Guideline

Consensus Recommendations for the Diagnosis and Management of Pancreatic Neuroendocrine Tumors: Guidelines from a Canadian National Expert Group.
Singh S, Dey C, Kennecke H, Kocha W, Maroun J, Metrakos P, Mukhtar T, Pasieka J, Rayson D, Rowsell C, Sideris L, Wong R, Law C.
Ann Surg Oncol. 2014 Nov 4. [Epub ahead of print]


Neuroendocrine tumors, version 1.2015.
Kulke MH, Shah MH, Benson AB 3rd, Bergsland E, Berlin JD, Blaszkowsky LS, Emerson L, Engstrom PF, Fanta P, Giordano T, Goldner WS, Halfdanarson TR, Heslin MJ, Kandeel F, Kunz PL, Kuvshinoff BW 2nd, Lieu C, Moley JF, Munene G, Pillarisetty VG, Saltz L, Sosa JA, Strosberg JR, Vauthey JN, Wolfgang C, Yao JC, Burns J, Freedman-Cass D.
J Natl Compr Canc Netw. 2015 Jan;13(1):78-108.


Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.

Lenders JW1, Duh QY, Eisenhofer G, Gimenez-Roqueplo AP, Grebe SK, Murad MH, Naruse M, Pacak K, Young WF Jr; Endocrine Society.J Clin Endocrinol Metab. 2014 Jun;99(6):1915-42. doi: 10.1210/jc.2014-1498.


Leitlinienprogramm Onkologie der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e.V. (AWMF) , der Deutschen Krebsgesellschaft e.V. (DKG) und der Deutschen Krebshilfe.