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Coronavirus-Pandemie (COVID-19) und onkologische Patientenversorgung

PRRT bei NEN G3

PRRT in high-grade gastroenteropancreatic neuroendocrine neoplasms (WHO G3).
Sorbye H, Kong G, Grozinsky-Glasberg S.
Endocr Relat Cancer. 2019 Dec 1. pii: ERC-19-0400.R1. doi: 10.1530/ERC-19-0400. [Epub ahead of print] Review.

Immuntherapie bei NEN - Duale Therapie mit Ipilimumab und Nivolumab bei NEN G3

A Phase II Basket Trial of Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors (DART SWOG 1609) in Patients with Non-Pancreatic Neuroendocrine Tumors.
Patel SP, Othus M, Chae YK, Giles FJ, Hansel DE, Singh PP, Fontaine A, Shah MH, Kasi A, Al Baghdadi T, Matrana M, Gatalica Z, Korn WM, Hayward J, McLeod C, Chen HX, Sharon E, Mayerson E, Ryan CW, Plets M, Blanke CD, Kurzrock R.
Clin Cancer Res. 2020 Jan 22. pii: clincanres.3356.2019. doi: 10.1158/1078-0432.CCR-19-3356. [Epub ahead of print]

Treatment of atypical pulmonary carcinoid with combination ipilimumab and nivolumab.
Nestor J, Barnaby K, Esposito M, Seetharamu N.
BMJ Case Rep. 2019 Nov 28;12(11). pii: e231029. doi: 10.1136/bcr-2019-231029.

Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Neuroendocrine Tumors: Results From the Phase 2 KEYNOTE-158 Study.
Strosberg JR, Mizuno N, Doi T, Grande E, Delord JP, Shapira-Frommer R, Bergsland EK, Shah MH, Fakih M, Takahashi S, Piha-Paul SA, O'Neil BH, Thomas S, Lolkema M, Chen M, Ibrahim N, Norwood KG, Hadoux J.
Clin Cancer Res. 2020 Jan 24. pii: clincanres.3014.2019. doi: 10.1158/1078-0432.CCR-19-3014. [Epub ahead of print]

NEC des Colon und BRAF Mutationen

Targeting BRAF Mutations in High-Grade Neuroendocrine Carcinoma of the Colon.
Burkart J, Owen D, Shah MH, Abdel-Misih SRZ, Roychowdhury S, Wesolowski R, Haraldsdottir S, Reeser JW, Samorodnitsky E, Smith A, Konda B.
J Natl Compr Canc Netw. 2018 Sep;16(9):1035-1040. doi: 10.6004/jnccn.2018.7043.

BRAFV600E mutation: A promising target in colorectal neuroendocrine carcinoma.
Dizdar L, Werner TA, Drusenheimer JC, Möhlendick B, Raba K, Boeck I, Anlauf M, Schott M, Göring W, Esposito I, Stoecklein NH, Knoefel WT, Krieg A.
Int J Cancer. 2019 Mar 15;144(6):1379-1390. doi: 10.1002/ijc.31828. Epub 2018 Oct 30.