Herr PD Dr. med. Jakob Siedlecki, FEBO

Oberarzt

Studium

  • Studium der Medizin an der Ludwig-Maximilians-Universität München (2008-2010)
  • Studium der Medizin an der Technischen Universität München (2010-2015)
  • Approbation als Arzt (Deutsches Staatsexamen: sehr gut) (06/2015)

Ophthalmologische Weiterbildung

  • Facharztausbildung an der Augenklinik der Ludwig-Maximilians-Universität München (2015-2021)
  • Forschungstätigkeit im Fachgebiet Refraktive Chirurgie, SMILE Eyes Linz & Ordination Dirisamer/Priglinger, Linz, Österreich (seit 2018)
  • Promotion (summa cum laude), Zellbiologisches Labor der Augenklinik der Universität München, LMU (06/2019)
  • Facharzt für Augenheilkunde (Bayerische Landesärztekammer, 03/2021)
  • Fellow of the European Board of Ophthalmologists (FEBO, 06/2021) 
  • Lehrbefähigung und Lehrbefugnis (Habilitation) für das Fach Augenheilkunde (08/2021, LMU München)

Klinische Spezialgebiete

  • Erkrankungen der Netzhaut, insbesondere der Makula
  • Linsen- und Netzhautchirurgie
  • Ophthalmologische Bildgebung
  • Refraktive Chirurgie

Forschungsschwerpunkte

  • Altersbedingte Makuladegeneration (AMD)
  • Pachychoroidale Erkrankungen der Makula (Chorioretinopathia centralis serosa, Polypoidale Choroidale Vaskulopathie etc.)
  • Refraktive Chirurgie (Small-incision lenticule extraction (SMILE), Laser-in-situ keratomileusis (LASIK), Photorefraktive Keratektomie (PRK), Implantable Collamer Lens (ICL))

Lehre

  • MECUMLMU (Studentenunterricht an der LMU; seit 2015)
  • Betreuung von Doktoranden (seit 2015)

Verlagstätigkeit

  • Associate Editor (Acta Ophthalmologica)
  • Executive Scientific Assistant (Klinische Monatsblätter für Augenheilkunde)

Auslandsaufenthalte

  • Landspitali University Hospital, Reykjavik, Island (2011)
  • Inselspital Bern, Schweiz (2014)

Auszeichnungen/Preise

  • Forschungspreis der Dieter Bumiller-Stiftung (2018)
  • Forschungspreis der Dieter Bumiller-Stiftung (2017)
  • Vortragspreis der DGII (Deutschsprachige Gesellschaft für Intraokularlinsen-Implantation, interventionelle und refraktive Chirurgie
  • Forschungsstipendium des Friedrich-Baur-Instituts (2016/2017))
  • Reisestipendium der Deutschen Retinologischen Gesellschaft (2016)
  • Alumnus der Studienstiftung des deutschen Volkes (seit 2015)
  • Alumnus des Max Weber-Programms Bayern (seit 2015)

Fachgesellschaften

  • AAO (American Academy of Ophthalmology)
  • APAO (Asia-Pacific Organization of Ophthalmology)
  • EURETINA (European Society of Retina Specialists)
  • ESCRS (European Society of Cataract and Refractive Surgeons)
  • DOG (Deutsche Ophthalmolgische Gesellschaft)

Publikationen (Stand: September 2021)

  • Schworm B, Luft N, Keidel LF, Kreutzer TC, Herold TR, Priglinger SG, Siedlecki J. Vanishing pachy-choroid in pachychoroid neovasculopathy under long- term anti-vascular endothelial growth factor therapy. BMC Ophthalmol. 2021 Jun 30;21(1):269.
  • Schworm B, Siedlecki J, Keidel LF, Herold TR, Luft N, Priglinger SG. Subthreshold laser therapy with a standardized macular treatment pattern in chronic central serous chorioretinopathy. Graefes Arch Clin Exp Ophthalmol. 2021 Jun 10.
  • Hagenau F, Nobl M, Vogt D, Schworm B, Siedlecki J, Kreutzer T, Luft N, Priglinger S. Highly Concentrated Autologous Platelet-Rich Plasma Restores Foveal Anatomy in Lamellar Macular Hole Surgery. Klin Monbl Augenheilkd. 2021 Aug;238(8):885-892. English.
  • Keidel LF, Schworm B, Priglinger SG, Siedlecki J. Pachychoroid Neovasculopathy Disguising as Age-Related Macular Degeneration Treated by Spironolactone and Anti-VEGF Combination Therapy. Case Rep Ophthalmol. 2021 Apr 9;12(1):116-123.
  • Siedlecki J, Pulido J, Priglinger S. Minimal Residual Disease in Neovascular Age-Related Macular Degeneration. Klin Monbl Augenheilkd. 2021 Jun;238(6):700-702. English.
  • Vounotrypidis E, Hillenmayer A, Wertheimer CM, Athanasiou A, Siedlecki J, Orth M, Ohlmann A, Priglinger SG, Wolf A. In vitro evaluation of simulated stereotactic radiotherapy for wet age-related macular degeneration on three different cell lines. Sci Rep. 2021 Apr 13;11(1):8068.
  • Lischke R, Mayer WJ, Feucht N, Siedlecki J, Wiltfang R, Kook D, Priglinger SG, Luft N. Total keratometry for determination of true corneal power after myopic small incision lenticule extraction. J Cataract Refract Surg. 2021 Feb 24.
  • Pavlou M, Schön C, Occelli LM, Rossi A, Meumann N, Boyd RF, Bartoe JT, Siedlecki J, Gerhardt MJ, Babutzka S, Bogedein J, Wagner JE, Priglinger SG, Biel M, Petersen-Jones SM, Büning H, Michalakis S. Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders. EMBO Mol Med. 2021 Apr 9;13(4):e13392.
  • Asani B, Siedlecki J, Schworm B, Mayer WJ, Kreutzer TC, Luft N, Priglinger SG. 3D Heads-Up Display vs. Standard Operating Microscope Vitrectomy for Rhegmatogenous Retinal Detachment. Front Med (Lausanne). 2020 Dec 22;7:615515.
  • Siedlecki J, Koch C, Schworm B, Liegl R, Kreutzer T, Kortuem KU, Schumann R, Priglinger SG, Wolf A. Enlargement rate of geographic atrophy before and after secondary CNV conversion with associated anti-VEGF treatment. BMC Ophthalmol. 2021 Jan 5;21(1):4.
  • Priglinger SG, Siedlecki J, Hattenbach LO, Grisanti S. Proliferative Vitreoretinopathie(PVR)-Chirurgie: „Scar Wars“ : Fünf Schritte zur erfolgreichen Therapie der PVR-Amotio [Proliferative vitreoretinopathy (PVR) surgery: Scar Wars : Five steps to successful treatment of PVR detachment]. Ophthalmologe. 2021 Jan;118(1):18-23. German.
  • Mohr N, Shajari M, Krause D, Kassumeh S, Siedlecki J, Priglinger SG, Mayer WJ, Luft N. Pellucid marginal degeneration versus keratoconus: distinction with wide-field SD-OCT corneal sublayer pachymetry. Br J Ophthalmol. 2020 Oct 14:bjophthalmol-2020-316496.
  • Wertheimer CM, Elhardt C, Wartak A, Luft N, Kassumeh S, Dirisamer M, Siedlecki J, Vounotrypidis E, Priglinger SG, Mayer WJ. Corneal optical density in Fuchs endothelial dystrophy determined by anterior segment optical coherence tomography. Eur J Ophthalmol. 2021 Jul;31(4):1771-1778.
  • Schworm B, Luft N, Keidel LF, Herold TR, Wolf A, Priglinger SG, Siedlecki J. Ranibizumab non-response in pachychoroid neovasculopathy: Effects of switching to aflibercept. Sci Rep. 2020 May 21;10(1):8439.
  • Siedlecki J, Fischer C, Schworm B, Kreutzer TC, Luft N, Kortuem KU, Schumann RG, Wolf A, Priglinger SG. Impact of Sub-Retinal Fluid on the Long-Term Incidence of Macular Atrophy in Neovascular Age-related Macular Degeneration under Treat & Extend Anti-Vascular Endothelial Growth Factor Inhibitors. Sci Rep. 2020 May 15;10(1):8036.
  • Siedlecki J, Luft N, Priglinger SG. Questions on a Study on the Effects of Flavanol-Rich Dark Chocolate on Visual Function and Retinal Perfusion-Reply. JAMA Ophthalmol. 2020 Jul 1;138(7):799-800.
  • Siedlecki J, Brantl V, Schworm B, Mayer WJ, Gerhardt M, Michalakis S, Kreutzer T, Priglinger S. COVID-19: Ophthalmological Aspects of the SARS-CoV 2 Global Pandemic. Klin Monbl Augenheilkd. 2020 May;237(5):675-680.
  • Luft N, Siedlecki J, Schworm B, Kreutzer TC, Mayer WJ, Priglinger SG, Dirisamer M. Intraocular Lens Power Calculation after Small Incision Lenticule Extraction. Sci Rep. 2020 Apr 6;10(1):5982.
  • Siedlecki J, Schmelter V, Schworm B, Mayer WJ, Priglinger SG, Dirisamer M, Luft N. Corneal wavefront aberrations and subjective quality of vision after small incision lenticule extraction. Acta Ophthalmol. 2020 Nov;98(7):e907-e913.
  • Siedlecki J, Schmelter V, Mayer WJ, Schworm B, Priglinger SG, Dirisamer M, Luft N. SMILE Versus Implantable Collamer Lens Implantation for High Myopia: A Matched Comparative Study. J Refract Surg. 2020 Mar 1;36(3):150-159.
  • Schworm B, Luft N, Keidel LF, Hagenau F, Kern C, Herold T, Kortuem KU, Priglinger SG, Siedlecki J. Response of neovascular central serous chorioretinopathy to an extended upload of anti-VEGF agents. Graefes Arch Clin Exp Ophthalmol. 2020 May;258(5):1013-1021.
  • Siedlecki J, Schworm B, Priglinger SG. The Pachychoroid Disease Spectrum-and the Need for a Uniform Classification System. Ophthalmol Retina. 2019 Dec;3(12):1013-1015.
  • Schmelter V, Dirisamer M, Siedlecki J, Shajari M, Kreutzer TC, Mayer WJ, Priglinger SG, Luft N. Determinants of subjective patient-reported quality of vision after small-incision lenticule extraction. J Cataract Refract Surg. 2019 Nov;45(11):1575-1583.
  • Siedlecki J, Mohr N, Luft N, Schworm B, Keidel L, Priglinger SG. Effects of Flavanol-Rich Dark Chocolate on Visual Function and Retinal Perfusion Measured With Optical Coherence Tomography Angiography: A Randomized Clinical Trial. JAMA Ophthalmol. 2019 Dec 1;137(12):1373-1379.
  • Siedlecki J, Luft N, Priglinger SG, Dirisamer M. Enhancement Options After Myopic Small-Incision Lenticule Extraction (SMILE): A Review. Asia Pac J Ophthalmol (Phila). 2019 Sep-Oct;8(5):406-411.
  • Siedlecki J Siedlecki M, Luft N, Kook D, Meyer B, Bechmann M, Wiltfang R, Sekundo W, Priglinger SG, Dirisamer M. Surface Ablation vs. CIRCLE for Myopic Enhancement after SMILE: A matched comparative study. Journal of refractive surgery. 2019;35(5):294-300.
  • Siedlecki J, Vounotrypidis E, Vogt D, Wolf A, Priglinger SG, Schumann RG. Lamellar hole-associated epiretinal proliferation presenting with perifoveal exudative vascular anomalous complex. American journal of ophthalmology case reports. 2019;14:112-116.
  • Siedlecki J, Luft N, Keidel L, Mayer WJ, Kreutzer TC, PriglingerSG, ArcherTJ, Reinstein DZ, Dirisamer M. Variation of lenticule thickness for SMILE in Low Myopia. Journal of refractive surgery. 2018;34(7):453-459
  • Luft N, Schumann RG, Dirisamer M, Kook D, Siedlecki J, Wertheimer C, Priglinger SG, Mayer WJ. Wound Healing, Inflammation, and Corneal Ultrastructure After SMILE and Femtosecond Laser-Assisted LASIK: A Human Ex Vivo Study. Journal of refractive surgery. 2018;34(6):393-399.
  • Wertheimer C, Kueres A, Siedlecki J, Braun C, Kassumeh S, Wolf A, Mayer W, Priglinger C, Priglinger S, Eibl-Lindner K. The intraocular lens as a drug delivery device for an epidermal growth factor-receptor inhibitor for prophylaxis of posterior capsule opacification. Acta Ophthalmologica. 2018;96(7):e874-e882
  • Siedlecki J, Asani B, Wertheimer C, Hillenmayer A, Ohlmann A, Priglinger C, Priglinger S, Wolf A, Eibl-Lindner K. Combined VEGF/PDGF inhibition using axitinib induces alphaSMA expression and a pro-fibrotic phenotype in human pericytes. Graefe's Archive for Clinical and Experimental Ophthalmology. 2018;256(6):1141-1149
  • Siedlecki J, Luft N, Mayer WJ, Siedlecki M, Kook D, Meyer B, Bechmann M, Wiltfang R, Priglinger SG, Dirisamer M. CIRCLE Enhancement After Myopic SMILE. Journal of refractive surgery. 2018;34(5):304-309.
  • Luft N, Siedlecki J, Sekundo W, Wertheimer C, Kreutzer TC, Mayer WJ, Priglinger SG, Dirisamer M. Small incision lenticule extraction (SMILE) monovision for presbyopia correction. European journal of ophthalmology. 2018;28(3):287-293.
  • Schumann RG, Vogt D, Haritoglou C, Hagenau F, Siedlecki J, Wolf A, Priglinger SG. [Histopathological correlation of epiretinal tissue in lamellar macular holes and macular pseudoholes]. Der Ophthalmologe. 2017;114(12):1110-1116.
  • Siedlecki J, Luft N, Kook D, Wertheimer C, Mayer WJ, Bechmann M, Wiltfang R, Priglinger SG, Sekundo W, Dirisamer M. Enhancement after myopic small incision lenticule extraction (SMILE) using surface ablation. Journal of refractive surgery. 2018;33(8):513-518
  • Siedlecki J, Mackert MM, Wolf A, Berking C, Priglinger SG, Eibl-Lindner K. Bilateral visual field defects in a patient treated with Trametinib and Dabrafenib for melanoma of unknown origin. Retinal Cases and Brief Reports. 2019;13(3):215-219.
  • Siedlecki J, Reiterer V, Leicht S, Foerster S, Kortüm K, Schaller U, Priglinger SG, Fuerweger C, Muacevic A, Eibl-Lindner KIncidence of secondary glaucoma after treatment of uveal melanoma with robotic radiosurgery versus brachytherapy. Acta Ophthalmologica. 2017;95(8):e734-e739. 
  • Siedlecki J, Wertheimer C, Wolf A, Liegl R, Priglinger C, Priglinger S, Eibl- Lindner, K. Combined VEGF and PDGF inhibition for neovascular AMD: anti- angiogenic properties of axitinib on human endothelial cells and pericytes in vitro. Graefe's Archive for Clinical and Experimental Ophthalmology. 2017;255(5):963-972
  • Wertheimer C, Siedlecki J, Kook D, Mayer W, Wolf A, Klingenstein A, Kampik A, Eibl-Lindner K: EGF-Receptor Inhibitor Gefitinib attenuates posterior capsule opacification in vitro and in the ex vivo human capsular bag model. Graefe's Archive for Clinical and Experimental Ophthalmology. 2015;253(3): 409-17 
  • Liegl R, Koenig S, Siedlecki J, Haritoglou C, Kampik A, Kernt M: Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cells via mTOR inhibition and decreases VEGF and PDGF expression. PLoS One. 2014 Feb 26;9(2): e88203. 
  • Thiele S, Liegl RG, König S, Siedlecki J, Langer J, Eibl K, Haritoglou C, Kampik A, Kernt M: [Multikinase-Inhibitors as new therapy option in neovascular AMD: In-vitro evaluation of the intravitreal safety-profile of Axitinib, Pazopanib and Sorafenib]. Klinische Monatsblätter für Augenheilkunde. 2013; 230(3): 247-254

  Verantwortlich für den Inhalt: PD Dr. J. Siedlecki