Original Papers

2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004

 

2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990

 

1989 1988 1987 1983

 

Doctoral students as co-authors are marked in blue (starting in 1998)

 

2017

 
182. Cornelia V*, May P*, Gottschlich A*, Markota A, Wenk D, Gerlach I, Voigt S, Stathopoulos GT, Arendt K, Heise CRataj F, Janssen KP,  Königshoff M, Winter H, Himsl I, Thasler W,  Schnurr MRothenfußer SEndres S, Kobold S.
Cancer cells induce...
PNAS 2017, in press
JIF 9,6
* contributed equally to this study

 

JIF 4,3181. Ahlfeld J, Filser S, Schmidt F, Wefers AK, Merk DJ, Glaß R, Herms J, Schüller U.
Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex.
Scientific Report - Nature 2017, 7:6137
JIF 4,3

 

181. Wennhold K, Thelen M, Haustein N, Reuter S, Rataj F, Kobold S, Garcia-Marquez M, Schlösser H, Chakupurakal G, Theurich S, Hallek M, Shimabukuro-Vornhagen A, von Bergwelt-Baildon M.
Exploiting effector functions of tumorantigen-specific CD40B cells for cancer immunotherapy
Cancer Immunology Research 2017, 5:730-743
JIF 8,3
  
2016

 

181. Freier CP, Kuhn C, Endres S, Mayr D, Freise K, Jeschke U, Anz D.
FOXP3+ cells recruited by CCL22 into breast cancer correlates with less tumor nodal infiltration.
Anticancer Research 2016; 36:3139-45.
JIF 1.9
  
180. Tufman A, Huber RM, Völk S, Aigner F, Edelmann M, Gamarra F, Kiefl R, Kahnert K, Tian F, Boulesteix AL, Endres S, Kobold S.
Interleukin-22 is elevated in lavage from patients with lung cancer and other pulmonary diseases.
BMC Cancer 2016; 16:409.
JIF 3.8
  
179. Wiedemann G, Jacobi S, Chaloupka M, Hamm S, Strobl S, Baumgartner R, Rothenfusser S, Duewell P, Endres S, Kobold S.
A novel TLR7 agonist reverses NK cell anergy and cures lymphoma-bearing mice.
Oncoimmunology 2016; 5:e1189051.
JIF 6.3 
  

178. Wiedemann G, Knott M, Vetter V, Rapp M, Haubner S, Fesseler J, Kühnemuth B, Layritz P,
Thaler R, Kruger S, Ormanns S, Mayr D, Endres S, Anz D.
Cancer cell-derived IL-1α induces CCL22 and the recruitment of regulatory T cells.
Oncoimmunology 2016; 5:e1175794.
JIF 6.3
  
177. Roskopf CC, Braciak TA, Fenn NC, Kobold S, Fey GH, Hopfner KP, Oduncu FS.
Dual-targeting triplebody 33-3-19 mediates selective lysis of biphenotypic CD19+ CD33+ leukemia cells.
Oncotarget 2016; 7:22579-89.                                                   
JIF 6.6
  
 
177. Pritsch M, Ben-Khaled N, Chaloupka  M, Kobold S, Berens-Riha N, Peter A, Liegl G, Schubert  S, Hölscher M, Löscher T, Wieser A.
Comparison of intranasal outer membrane vesicles with cholera toxin and injected MF59C.1 as adjuvants for malaria transmission blocking antigens AnAPN1 and Pfs48/45.
Journal of Immunology Research 2016; 2016:3576028.                    
JIF 2.9
 

177. Castoldi R, Schanzer J, Panke C, Jucknischke U, Neubert N, Croasdale R, Klein C,
Scheuer W, Niederfellner G, Auer J, Kobold S, Sustmann C.
TetraMabs: Simultaneous targeting of four oncogenic receptor tyrosine kinases for tumor growth inhibition in heterogeneous tumor cell populations.
Protein Engineering Design and Selection 2016; 29:467-75.                                                    
JIF 2.5
  

177. Heidegger S, Gößl D, Schmidt A, Niedermayer S, Argyo Ch, Endres S, Bein T, Bourquin C.
Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery.
Nanoscale 2016; 8:938-48.
JIF 7.4

 

 

2015

  

176. Heidegger S, Jarosch A, Schmickl M, Endres S, Bourquin C, Hotz C.
Mycoplasma hyorhinis-contaminated cell lines activate primary innate immune cells via a protease-sensitive factor.
PLOS ONE 2015; 10:e0142523.
JIF 3.7
  

 

175. Rapp MGrassmann SChaloupka M, Layritz P, Kruger S, Ormanns S, Rataj F, Janssen KP, Endres S, Anz D, Kobold S.
C-C chemokine receptor type-4 transduction of T cells enhances interaction with dendritic cells, tumor infiltration and therapeutic efficacy of adoptive T cell transfer.
Oncoimmunology 2015; 5:e1105428.
JIF 6.3
  

174. Lichtenegger F, Kondla I, Krempasky M, Weber A, Herold T, Krupka C, Spiekermann K.
RNA and protein expression of herpesvirus entry mediator (HVEM) is associated with molecular markers, immunity-related pathways and relapse-free survival of patients with AML.
Cancer Immunology Immunotherapy 2015; 64:1505-15.
JIF 4.0

 

174. Anz D, Rapp M, Eiber S, Koelzer V, Thaler R, Haubner S, Knott M, Nagel S, Golic M, Wiedemann G, Bauernfeind F, Wurzenberger C, Hornung V, Scholz C, Mayr D, Rothenfusser S, Endres S, Bourquin C.
Suppression of intratumoral CCL22 by type I interferon inhibits migration of regulatory T cells and blocks cancer progression. 
Cancer Research 2015; 75:4483-93.
JIF 9.3

 

173. Häcker G, Senft D, Weber A, Saathoff F, Berking C, Heppt M, Kammerbauer C, Rothenfusser S, Kellner S, Kurgys Z, Besch R.
In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.
Cell Death and Disease 2015; 6:e1996.

JIF 5.0

 

173. Hotz C, Roetzer L, Huber T, Sailer A, Oberson A, Treinies M, Heidegger S, Herbst T, Endres S, Bourquin C.
TLR and RLR signaling are reprogrammed in opposite directions after detection of viral infection.
The Journal of Immunology 2015; 195:4387-95.

JIF 5.4

 

172. Schnarfell F, Lichtenegger F, Emmerig K, Schlueter M, Neitz J, Draenert R, Hiddemann W, Subklewe M.
T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment.
Journal of Haematology and Oncology 2015; 8:93.

JIF 4.9

 

172. Kobold* S, Grassmann* S, Chaloupka M, Lampert C, Wenk S, Kraus F, Rapp M, Duewell P, Zeng Y, Schmollinger J, Schnurr M, Endres S#, Rothenfußer S#.
Impact of a new fusion receptor on PD-1-mediated immunosuppression in adoptive T cell therapy.
The Journal of the National Cancer Institute 2015; 107.
* contributed equally to this study, # share senior authorship

JIF 15.2                                                                         http://www.ncbi.nlm.nih.gov/pubmed/26105028


171. Freier C, Kuhn C, Rapp M, Endres S, Mayr D, Friese K, Anz D, Jeschke U.
Expression of CCL22 and infiltration by regulatory T-cells are increased in the decidua of human miscarriage placentas.
American Journal of Reproductive Immunology 2015; 74:216-27.
JIF 2.7

 

170. Duewell P, Beller E, Kirchleitner S, Adunka T, Bourhis H, Siveke J, Mayr D, Kobold S, Endres S, Schnurr M.
Targeted activation of melanoma differentiation-associated protein 5 (MDA5) for immunotherapy of pancreatic carcinoma.
OncoImmunology 2015; 4:e1029698.

JIF 6.3

 

169. Bauer C, Hees C, Sterzik A, Bauernfeind F, Mak´Anyengo R, Duewell P, Lehr HA, Noessner E, Wank R, Trauzold A, Endres S, Dauer M, Schnurr M.
Pro- and anti-apoptotic proteins of the Bcl-2 family regulate sensitivity of pancreatic cancer cells towards gemcitabine and T cell-mediated cytotoxicity.
Journal of Immunotherapy 2015; 38:116-26.

JIF 3.4

 

168. Kocabey S, Meinl H, MacPherson IS, Cassinelli V, Manetto A, Rothenfusser S, Liedl T, Lichtenegger FS.
Cellular uptake of Tile-assembled DNA nanotubes.
Journal of Nanomaterials 2015; 47-60.
JIF 2.4


168. Hoffmann F, Schmidt A, Dittmann Chevillotte M, Wisskirchen C, Hellmuth JC, Willms S, Gilmore RH, Glas J, Folwaczny M, Müller T, Berg T, Spengler U, Fitzmaurice K, Kelleher D, Reisch N, Rice CM, Endres S, Rothenfusser S.
Polymorphisms in MDA-5 link protein function to clearance of hepatitis C virus.
Hepatology 2015; 61:460-70.

JIF 10.4

 

 

2014

 

167. Kobold S, Steffen J, Chaloupka M, Grassmann S, Henkel J, Castoldi R, Zeng Y, Chmielewski M, Schmollinger J, Schnurr M, Rothenfußer S, Schendel DJ, Abken H, Sustmann C, Niederfellner CG, Klein C, Bourquin C, Endres S.
Selective bispezific T cell recruiting antibody enhances anti-tumor activity of adoptive T cell transfer.
The Journal of the National Cancer Institute 2014; 107:364
JIF 15.2

 

166. Duewell P, Steger A, Lohr H, Bourhis H, Hoelz H, Kirchleitner SV, Stieg MR, Grassmann S, Kobold S, Siveke JT, Endres S, Schnurr M.

RIG-I-like helicases induce immunogenic cell death of pancreatic cancer and sensitize tumors killing by CD8+ T-cells.
Cell Death and Differentiation 2014; 21:1825-37.
JIF 8.4

  

165. Roskopf CC, Schiller C, Braciak TA, Kobold S, Schubert A, Fey GH, Hopfner KP, Oduncu F.
T cell-recruiting triplebody 19-3-19 mediates serial lysis of malignant B-lymphoid cells by a single T cell.
Oncotarget 2014; 5:6466-83.
JIF 6.6

 

165. Luetkens T, Kobold S, Cao Y, Ristic M, Schilling G, Tams S, Bartels BM, Templin J, Bartels K, Hildebrandt Y, Yousef S, Marx A, Haag F, Bokemeyer C, Kröger N, Atanackovic D.
Functional autoantibodies against SSX-2 and NY-ESO-1 in multiple myeloma patients after allogeneic stem cell transplantation.
Cancer Immunology Immunotherapy 2014; 63:1151-62.
JIF 3.6

 

165. Wilson NS, Duewell P, Yang B, Li Y, Marsters S, Koernig S, Latz E, Maraskovsky E, Morelli AB, Schnurr M, Ashkenazi A.
Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.
The Journal of Immunology 2014; 192:3259-68.
JIF 5.5

 

165. Krupka C, Kufer P, Kischel R, Zugmaier G, Bögeholz J, Köhnke T, Lichtenegger FS, Schneider S, Metzeler KH, Fiegl M, Spiekermann K, Baeuerle PA, Hiddemann W, Riethmüller G, Subklewe M.
CD33 target validation and sustained depletion of AML blasts in long-term cultures by the bispecific T-cell-engaging antibody AMG 330.
Blood 2014; 123:356-65.
JIF 9.9

 

165. Bauer C, Sterzik A, Bauernfeind F, Duewell P, Conrad C, Kiefl R, Endres S, Eigler A, Schnurr M, Dauer M.
Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T-cell and B-cell responses but improves clinical efficacy in an murine pancreatic carcinoma model.
Cancer Immunology Immuntherapy 2014; 63:321-33.
JIF 3.6

 

164. Kim S, Kaiser V, Beier E, Bechheim M, Guenthner-Biller M, Ablasser A, Berger M, Endres S, Hartmann G, Hornung V.
Self-priming determines high type I IFN production by plasmacytoid dendritic cells.
European Journal of Immunology 2014; 44:807-18.
JIF 5.0

 

163. Kulkarni P. O*, Hartter I*, Mulay R. S*, Hagemann J, Darisipudi N. M, Kumar S, Romoli S, Thomasova D, Ryu M, Kobold S, Anders HJ.
TLR4-induced IL-22 release accelerates kidney regeneration.
Journal of the American Society of Nephrology 2014; 25:978-89.
JIF 9.0 *diese Autoren leisteten gleichwertigen Beitrag

 

163. Anz D, Kruger S, Haubner S, Rapp M, Bourquin C, Endres S.
The dipeptidylpeptidase-IV inhibitors sitagliptin, vildagliptin and saxagliptin do not impair innate and adaptive immune responses.
Diabetes, Obesity and Metabolism 2014; 16:569-72.
JIF 5.2

 

162. Kobold S, Merk M, Hofer L, Peters P, Bucala R, Endres S.
The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model.
Oncotarget 2014; 5:103-7.
JIF 6.6

 

 

2013

 

161. Heidegger S*, Anz D*, Stephan N, Bohn B, Herbst T, Fendler WP, Suhartha N, Sandholzer N, Kobold S, Hotz C, Eisenaecher K, Radtke-Schuller S, Endres S, Bourquin C.
Virus-associated activation of innate immunity induces rapid disruption of Peyer’s patches in mice.
Blood 2013; 122:2591-9.
JIF 9.1 *diese Autoren leisteten gleichwertigen Beitrag

 

160. Kobold S, Völk S, Clauditz T, Küpper NJ, Minner S, Tufmann A, Düwell P, Lindner M, Koch I, Heidegger S, Merk M, Rothenfußer S, Schnurr M, Huber RM, Sauter G, Wilczak W, Endres S.
Interleukin-22 is frequently in lung cancer and may contribute to tumor progression in chemotherapy-resistant disease.
Journal of Thoracic Oncology 2013; 8:1032-1042.
JIF 4.5

 

159. Castoldi R, Ecker V, Wiehle L, Majety M, Busl-Schuller R, Asmussen M, Nopora A, Jucknischke U, Osl F, Kobold S, Scheuer W, Venturi M, Klein C, Niederfellner G, Sustmann C.
A novel bispecific EGFR/Met antibody blocks tumor promoting phenotypic effects induced by resistance to EGFR inhibition and has potent anti-tumor activity.
Oncogene 2013; 32:5593-601.
JIF 7.4

 

159. Hohenauer T, Berking C, Schmidt A, Haferkamp S, Senft D, Kammerbauer C, Fraschka S, Graf SA, Irmler M, Beckers J, Flaig M, Aigner A, Höbel S, Hoffmann F, Hermeking H, Rothenfusser S, Endres S, Ruzicka T, Besch R.
The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival.
EMBO Molecular Medicine 2013; 5:919-34.
JIF 7.8

 

158. Heidegger S, Kirchner SK, Stephan N, Bohn B, Suhartha N, Hotz C, Anz D, Sandholzer N, Stecher B, Rüssmann H, Endres S, Bourquin C.
TLR activation excludes circulating naive CD8+ T cells from gut-associated lymphoid organs in mice.
Journal of Immunology 2013; 190:5313-20.
JIF 5.5

 

157. Schmidt K, Zilio S, Schmollinger JC, Bronte V, Blankenstein T, Willimsky G.
Differently immunogenic cancers in mice induce immature myeloid cells that suppress.
CTL in vitro but not in vivo following transfer.
Blood 2013; 121:1740-8.
JIF 9.1

 

157. Ellermeier J, Wei J, Düwell P, Hoves S, Stieg M, Adunka T, Nörenberg D, Anders HJ, Mayr D,
Pöck H, Hartmann G, Endres S, Schnurr M.
Therapeutic efficacy of bifunctional siRNA combining TGF-β1 silencing with RIG-I activation in pancreatic cancer.
Cancer Research 2013; 73:1709-20.
JIF 8.7

 

156. Rieder F, Siegmund B, Bundschuh DS, Lehr HA, Endres S, Eigler A.
The selective phosphodiesterase 4 inhibitor roflumilast and phosphodiesterase 3/4 inhibitor pumafentrine reduce clincial score and TNF expression in experimental colitis in mice.
PLoS One 2013; 8:56867.
JIF 3.7

 

 

2012

 

155. Kobold S, Luetkens T, Bartels BM, Cao Y, Hildebrandt Y, Sezer O, Reinhard H, Templin J, Bartels K, Lajmi N, Haag F, Bokemeyer C, Kröger N, Atanackovic D.
Longitudinal analysis of tetanus- and influenza-specific IgG antibodies in myeloma patients.
Clinical and Developmental Immunology 2012; 2012:134081.
JIF 1.8

 

155. Vollbrecht T, Stirner R, Tufman A, Roider J, Huber RM, Bogner JR, Lechner A, Bourquin C,
Draenert R. Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells.
AIDS 2012; 26:F31-7.
JIF 6.4

 

155. Bauer C, Duewell P, Lehr HA, Endres S, Schnurr M.
Protective and aggravating effects of Nlrp3 inflammasome activation in IBD Models: influence of genetic and environmental factors.
Digestive Diseases 2012; 1:82-90.
JIF 2.7

 

154. Wenzel M, Wunderlich M, Besch R, Poeck H, Willms S, Schwantes A, Kremer M, Sutter G, Endres S, Schmidt A, Rothenfusser S.
Cytosolic DNA triggers mitochondrial apoptosis via DNA-damage signalling proteins independently of AIM2 and RNA polymerase III.
Journal of Immunology 2012; 188:394-403.
JIF 5.5

 

153. Dann A, Poeck H, Croxford A, Gaupp S, Kierdorf K, Knust M, Pfeifer D, Maihoefer C, Endres S,
Kalinke U, Meuth S, Wiendl H, Knobeloch KP, Akira S, Waisman A, Hartmann G, Prinz M.
Cytosolic RIG-like-helicases act as negative regulators of sterile inflammation in the CNS.
Nature Neuroscience 2012; 15:98-106.
JIF 15.3

 

 

2011

 

152. Schueller V, Heidegger S, Sandholzer N, Suhartha N, Nickels P, Endres S, Bourquin C, Liedl T.
Cellular immunostimulation by CpG-sequence-coated DNA origami structures.
American Chemical Society ACS Nano 2011; 5:9696-702.
JIF 12.1

 

151. Kobold S, Isernhagen J, Hübel K, Kilic N, Bogner C, Frickhofen N, Bokemeyer C, Fiedler W.
Plerixafor is effective and safe for stem cell mobilization in heavily pretreated germ cell tumor patients.
Bone Marrow Transplantation 2011; 46:1053-6.
JIF 3.5

 

151. Lech M, Kantner C, Kulkarni O, Ryu M, Vlasova E, Heesemann J, Anz D, Endres S, Martin J, Koichi S, Kobayashi K, Flavell RA, Anders HJ.
Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus.
Annals of the Rheumatic Diseases 2011; 70:2207-17.
JIF 9.1

 

150. Merk M, Zierow S, Leng L, Das R, Du X, Schulte W, Fan J, Lue H, Chen Y, Xiong H, Chagnon F, Bernhagen J, Lolis E, Mor G, Lesur O, Bucala R.
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).
Proceedings of the National Academy of Sciences USA 2011; 108:E577-85.
JIF 9.7

 

150. Anz D, Eiber S, Scholz C, Endres S, Kirchner T, Bourquin C, Mayr D.
In breast cancer a high ratio of tumor-infiltrating intraepithelial CD8+ to FoxP3+ cells is characteristic for the medullary subtype.
Histopathology 2011; 59:965-74.
JIF 2.9

 

149. Kobold S, Tams S, Luetkens T, Cao Y, Sezer O, Bartels BM, Reinhard H, Templin J, Bartels K, Hildebrandt Y, Lajmi N, Marx A, Haag F, Bokemeyer C, Kröger N, Atanackovic D.
Patients with multiple myeloma develop SOX2-Specific autoantibodies after allogeneic stem cell transplantation.
Clinical and Developmental Immunology 2011; 2011:302145.
JIF 3.1

 

149. Bourquin C, Hotz C, Noerenberg D, Völkl A, Heidegger S, Storch B, Sandholzer N,
Wurzenberger C, Anz D, Endres S.
Systemic cancer therapy with a small molecule agonist of Toll-like receptor 7 can be improved by circumventing TLR tolerance.
Cancer Research 2011; 71:5123-33.
JIF 8.7

 

148. Duewell P, Kisser U, Heckelsmiller K, Hoves S, Stoitzner P, Morelli AB, Koernig S, Clausen BE, Dauer M, Eigler A, Anz D, Bourquin C, Maraskovsky E, Endres S, Schnurr M.
ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells.
Journal of Immunology 2011; 187:55-63.
JIF 5.5

 

147. Bauer C, Dauer M, Saraj S, Bauernfeind F, Sterzik A, Junkmann J, Jakl V, Kiefl R, Schnurr M, Oduncu F, Emmerich B, Mussack T, Bruns C, Rüttinger D, Conrad C, Jauch KW, Endres S, Eigler A.
Dendritic cell-based vaccination of patients with advanced pancreatic carcinoma: results of a pilot study.
Cancer Immunology Immunotherapy 2011; 60:1097-107.
JIF 3.6

 

146. Zoglmeier C, Bauer H, Noerenberg D, Wedekind G, Bittner P, Sandholzer N, Rapp M, Anz D, Endres S, Bourquin C.
CpG blocks immune suppression by myeloid-derived suppressor cells in tumor-bearing mice. (see editorial: Lechner M, Epstein A. A new mechanism for blocking myeloid-derived suppressor cells by CpG. Clin Canc Res 2011 Feb.)
Clinical Cancer Research 2011; 17:1765-75.
JIF 7.8

 

145. Anz D, Mueller W, Golic M, Kunz WG, Rapp M, Koelzer VH, Ellermeier J, Ellwart JW, Schnurr M, Bourquin C, Endres S.
CD103 is a hallmark of tumor-infiltrating regulatory T cells.
International Journal of Cancer 2011;129:2417-26.
JIF 6.2

 

144. Jacobs C, Duewell P, Heckelsmiller K, Wei J, Bauernfeind F, Ellermeier J, Kisser U, Bauer C, Dauer M, Eigler A, Maraskovsky E, Endres S, Schnurr M.
An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma.
International Journal of Cancer 2011; 128:897-907.
JIF 6.2

 

 

2010

 

143. Gross O, Poeck H, Bscheider M, Dostert C,Hannesschlaeger N, Endres S, Tardivel A, Tschopp J, Ruland J.
Syk kinase signaling couples to the Nalp3 inflammasome for anti-fungal host defense.
Nature 2010; 459:433-6.
JIF 38.6

 

142. Bourquin C, Wurzenberger C, Heidegger S, Fuchs S, Anz D, Weigel S, Sandholzer N, Winter G, Coester C, Endres S.
Delivery of immunostimulatory RNA oligonucleotides by gelatin nanoparticles triggers an efficient antitumoral response.
Journal of Immunotherapy 2010; 339:935-44.
JIF 3.5

 

141. Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nunez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E.
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Nature 2010; 464:1357-6.
JIF 38.6

 

141. Bourquin C, von der Borch P, Zoglmeier C, Anz D, Sandholzer N, Wurzenberger C, Denzel A, Kammerer R, Zimmermann R, Endres S.
Efficient eradication of subcutaneous but not of autochthonous gastric tumors by adoptive T cell transfer in a SV40 T antigen mouse model.
Journal of Immunology 2010; 185:2580-8.
JIF 5.5

 

140. Bauer C, Duewell P, Mayer T, Lehr HA, Fitzgerald KA, Tschopp J, Endres S, Latz E, Schnurr M.
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NALP3 inflammasome.
Gut 2010; 59:1192-9.
JIF 10.7

 

139. Anz D, Koelzer VH, Moder S, Thaler R, Schwerd T, Lahl K, Sparwasser T, Besch R, Poeck H, Hornung V, Hartmann G, Rothenfusser S, Bourquin C, Endres S.
Immunostimulatory RNA blocks suppression by regulatory T cells.
Journal of Immunology 2010; 184:939-46.
JIF 5.5

 

 

2009

 

138. Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschläger N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J.
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin-1β production.
Nature Immunology 2009; 11:63-9.
JIF 26.2

 

137. Berchthold C, Panthel K, Jellbauer S, Köhn B, Roider E, Partilla M, Heesemann J, Endres S, Bourquin C, Rüssmann H.
Superior protective immunity against murine listeriosis by combined vaccination with CpG DNA and recombinant salmonella.
Infection and Immunity 2009; 77:5501-5508.
JIF 4.1

 

136. Bourquin C, Schmidt L, Lanz AL, Storch B, Wurzenberger C, Anz D, Berger M, Poeck H, Hartmann G, Hornung V, Endres S.
Immunostimulatory RNA oligonucleotides induce an effective antitumoral NK cell response through TLR7.
Journal of Immunology 2009; 183:6078-86.
JIF 5.5

 

135. Berger M, Ablasser A, Kim S, Bekeredjian-Ding I, Giese T, Endres S, Hornung V, Hartmann G.
TLR8-driven IL-12-dependent reciprocal and synergistic activation of NK cells and monocytes by immunostimulatory RNA.
Journal of Immunotherapy 2009; 32:262-71.
JIF 3.5

 

134. Schmidt A, Schwerd T, Hellmuth J, Sheng C, Wenzel M, Hoffmann F, Poeck H, Michallet MC, Besch R, Hopfner KP, Endres S, Rothenfusser S.
5'-triphosphate RNA requires base-paired structures to activate anti-viral signaling via RIG-I.
Proceedings of the National Academy of Sciences USA 2009; 106:12067-72.
JIF 9.7

 

133. Besch R, Poeck H, Hohenauer T, Senft D, Haecker G, Berking C, Hornung V, Endres S, Ruzicka T, Rothenfusser S, Hartmann G.
Proapoptotic signalling by RIG-I and MDA-5 results in tumorspecific apoptosis independent of type I interferons in melanoma.
Journal of Clinical Investigation 2009; 119:2399-411.
JIF 12.8

 

132. Ablasser A, Poeck H, Berger M , Schlee M, Kim S, Bourquin C, Goutagny N, Jiang Z, Fitzgerald KA, Anz D, Rothenfusser S , Endres S , Hartmann G, Hornung V.
Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.
Journal of Immunology 2009; 182:6824-33.
JIF 5.5

 

131. Bekeredjian-Ding I, Schaefer M, Hartmann E, Pies R, Parcina M, Schneider P, Giese T, Endres S, Wollenberg B, Hartmann G.
Tumour-derived prostaglandin E2 and transforming growth factor-β synergize to inhibit plasmacytoid dendritic cell-derived interferon-α.
Immunology 2009; 128:439-450.
JIF 3.7

 

130. Haasters F, Prall WC, Anz D, Endres S, Mutschler M, Dochenva D, Schieker M.
Morphological and immunological characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell culturing.
Journal of Anatomy 2009; 214:759-767.
JIF 2.4

 

129. Gross O, Poeck H, Bscheider M, Dostert C,Hannesschlaeger N, Endres S, Tardivel A, Tschopp J, Ruland J.
Syk kinase siganling couples to the Nalp3 inflammasome for anti-fungal host defense.
Nature 2009; 459:433-6.
JIF 38.6

 

128. Anz D, Thaler R, Stephan N,Waibler Z, Trauscheid MJ, Scholz C,Kalinke U, Barchet W, Endres S, Bourquin C.
Activation of melanoma differentiation-associated gene 5 (MDA5) and Toll-like receptors causes rapid involution of thymus.
Journal of Immunology 2009; 182:6044-50.
JIF 5.5

 

127. Wurzenberger C, Kölzer HV,Schreiber S , Anz D, Vollmar AM, Schnurr M, Endres S, Bourquin C.
Short-term activation induces multifunctional dendritic cells that generate potent antitumor T-cell responses in vivo.
Cancer Immunology Immunotherapy 2009; 58:901-13.
JIF 3.6

 

126. Schnurr M, Orban M , Robson NC, Shin A, Braley H, Airey D, Cebon J, Maraskovsky E, Endres S.
ISCOMATRIX adjuvant induces efficient cross-presentation of tumor Ag by dendritic cells via rapid cytosolic Ag delivery and processing via tripeptidyl peptidase II .
Journal of Immunology 2009; 182:1253-9.
JIF 5.5

 

 

2008

 

125. Allam R, Pawar RD, Kulkarni OP, Hornung V, Hartmann G, Segerer S, Akira S, Endres S, Anders HJ.
Viral 5'-triphosphate RNA and non CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses.
European Journal of Immunology 2008; 38:3487-3498.
JIF 5.0

 

124. Dauer M, Lam V, Arnold H, Junkmann J, Kiefl R, Bauer C, Schnurr M, Endres S, Eigler A.
Combined use of toll-like receptor agonists and prostaglandin E(2) in the FastDC model: rapid generation of human monocyte-derived dendritic cells capable of migration and IL-12p70 production.
Journal of Immunological Methods 2008; 337:97-105.
JIF 2.2

 

123. Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, Morskaya S S, Kirschnek S, Gaffal E, Landsberg J, Hellmuth J, Schmidt A, Anz D, Bscheider M, Schwerd T, Berking C, Bourquin C, Kalinke U, Kremmer E, Kato H, Akira S, Meyers R, Häcker G, Neuenhahn M, Busch D H, Rothenfusser S , Prinz M, Hornung V, Endres S, Tüting T, Hartmann G.
Therapeutic anti-tumor efficacy of 5´-triphosphate-siRNA depends on simultaneous gene-silencing and immuno-stimulatory activity.
Nature Medicine 2008; 14:1256-63.
JIF 24.3

 

122. Bourquin C , Anz D, Zwioreck K, Lanz AL, Fuchs S, Weigel S, Wurzenberger C, von der Borch P, Golic M, Winter G, Endres S.
Targeting CpG oligonucleotides to the lymph node by nanoparticels elicits efficient antitumoral immunity.
Journal of Immunology 2008; 1;181:2990-8.
JIF 5.5

 

121. Bourquin C, Haar M, Anz D, Sandholzer N, Neumaier I, Endres S, Skerra A, Schwab M, Linington C.
DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis.
European Journal of Pharmacology 2008; 588:99-105.
JIF 2.6

 

120. Zwiorek K, Bourquin C, Battiany J, Winter G, Endres S, Hartmann G, Coester C.
Delivery by cationic gelatin nanoparticles strongly increases the immunostimulatory effects of CpG Oligonucleotides.
Pharmaceutical Research 2008; 25:551-62.
JIF 4.7

 

119. Shin A, Toy T, Rothenfusser S, Robson N, Vorac J, Dauer M, Stuplich M, Endres S, CebonJ, Maraskovsky E, Schnurr M.
P2Y receptor signaling regulates phenotype and IFN-α secretion of human plasmacytoid dendritic cells.
Blood 2008; 111:3062-9.
JIF 9.1

 

 

2007

 

118. Bauer C, Bauernfeind F, Sterzik A, Orban M, Schnurr M, Lehr HA, Endres S, Eigler A, Dauer M.
Dendritic cell-based vaccination can be combined with gemcitabine to increase survival in a murine pancreatic carcinoma model.
Gut  2007; 5:1275-82.
JIF 3.0

 

117. Bauer C, Loher F, Dauer M, Mayer C, Lehr HA, Schönharting M, Hallwachs R, Endres S, Eigler A.
The ICE inhibitor pralnacasan prevents DSS-induced colitis in C57BL/6 mice and suppresses IP-10 mRNA, but not TNF-α expression.
Digestive Diseases and Sciences 2007; 52: 1642-52.
JIF 1.6

 

116. Bekeredjian-Ding I, Inamura S, Giese T, Moll H, Endres S, Sing A, Zähringer U, Hartmann G.
Staphylococcus aureus triggers T cell-independent B cell proliferation through the engagement of the B cell receptor and Toll-like receptor 2.
Journal of Immunology 2007; 178:2803-12.
JIF 6.7

 

115. Bourquin C, Schmid L, Hornung V, Wurzenberger C, Anz D, Sandholzer N, Schreiber S, Voelkl A, Hartmann G, Endres S.
Immunostimulatory RNA oligonucleotides trigger an antigen-specific cytoxic T cell and IgG2a response.
Blood 2007; 109: 2953-60.
JIF 10.1

 

 

2006

 

114. Hartmann E, Graefe H, Hopert A, Pries R, Rothenfusser S, Poeck H, Mack B, Endres S,
Hartmann G, Wollenberg B.
Analysis of plasmacytoid and myeloid dendritic cells in nasal epithelium.
Clinical and Vaccine Immunology 2006; 13:1278-86.
JIF 2.6

 

113. Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK,      Schlee M, Endres S, Hartmann G.
5'-triphosphate RNA is the ligand for RIG-I.
Science 2006; 314:994-7.
JIF 30.9

 

112. Kerkmann M, Lochmann D, Weyermann J, Sarris A, Poeck H, Wagner M, Battiany J, Zimmer A, Endres S, Hartmann G.
Immunostimulatory properties of CpG-oligonucleotides are enhanced by the use of protamine nanoparticles.
Oligonucleotides 2006; 16: 313-22.
JIF 3.1

 

111. Eigenbrod S, Derwand R, Jakl V, Endres S, Eigler A.
Sphingosine kinase and sphingosine-1-phosphate regulate migration, endocytosis and apoptosis of dendritic cells.
Immunological Investigations 2006; 35:149-65.
JIF 1.2

 

110. Dauer M, Schad K, Junkmann J, Herten J, Kiefl R, Schnurr M, Endres S, Eigler A.
IFN-α promotes definitive maturation of dendritic cells generated by short term culture of monocytes with GM-CSF and IL-4.
Journal of Leukocyte Biology 2006; 80:278-86.
JIF 4.3

 

109. Bekeredjian-Ding I, Roth S I, Gilles S, Giese T, Ablasser A, Hornung V, Endres S, Hartmann G.
T cell-independent TLR-induced IL-12p70 production in primary human monocytes.
Journal of Immunology 2006; 176:7438-46.
JIF 6.7

 

108. Bourquin C, Schreiber S, Beck S, Hartmann G, Endres S.
Immunotherapy with dendritic cells and CpG oligonucleotides can be combined with chemotherapy without loss of efficacy in a mouse model of colon cancer.
International Journal of Cancer 2006; 118:2790-5.
JIF 4.4

 

 

2005

 

107. Dauer M, Schad K, Herten J, Junkmann J, Bauer C, Kiefl R, Endres S, Eigler A.
FastDC derived from human monocytes within 48 hours effectively prime tumor antigen-specific cytotoxic cells.
Journal of Immunological Methods 2005; 302:145-55.
JIF 2.5

 

106. Marschner A, Rothenfusser S, Hornung V, Prell D, Krug A, Kerkmann M, Wellisch D, Poeck H, Greinacher A, Giese T, Endres S, Hartmann G.
CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells.
European Journal of Immunology 2005; 35:2347-57.
JIF 5.4

 

105. Dauer M, Herten J, Bauer C, Renner F, Schad K, Schnurr M, Endres S, Eigler A.
Chemosensitization of pancreatic carcinoma cells to enhance T cell-mediated cytotoxicity induced by tumor lysate-pulsed dendritic cells.
Journal of Immunotherapy 2005; 28:332-42.
JIF 4.0

 

104. Renner ED, Pawlita I, Hornung V, Hartl D, Albert M, Jansson A, Endres S, Hartmann G, Belohradsky BH, Rothenfusser S.
No indication for a defect in Toll like receptor signalling in patients with hyper IgE syndrome.
Journal of Clinical Immunology 2005; 25:321-8.
JIF 2.6

 

103. Bekeredjian-Ding I, Wagner M, Hornung V, Giese T, Schnurr M, Endres S, Hartmann G.
Plasmacytoid dendritic cells control TLR7 sensivity of naive B cells via type I IFN.
Journal of Immunology 2005; 174:4043-50.
JIF 6.7

 

102. Hartmann G, Marschner A, Renner-Viveros P, Stahl-Henning C, Eisenblätter M, Suh JS, Endres S, Tenner-Racz K, Racz P, Steinmann R, Ignatius R.
CpG oligonucleotides induce strong humoral but only weak CD4+ T cell responses to protein antigens in rhesus macaques in vivo.
Vaccine 2005; 23:3310-7.
JIF 2.8

 

101. Schlender J, Hornung V, Finke S, Guenthner-Biller M, Marozin S, Brzozka K, Moghim S, Endres S, Hartmann G, Conzelmann KK.
Inhibition of Toll-like-receptor 7 and 9-mediated type I IFN production in human plasmacytoid dendritic cells by respiratory syncytial virus and mesales Virus.
Journal of Virology 2005; 79:5507-15.
JIF 5.2

 

100. Hornung V, Guenthner-Biller M,Bourquin C, Ablasser A, Schlee M, Uematsu S, Manoharan M,      Akira S, de Fougerolles A, Endres S, Hartmann G.
Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7.
Nature Medicine 2005; 11:263-70.
JIF 30.6

 

99. Jahrsdorfer B, Mühlenhoff L, Blackwell S E, Wagner M, Poeck H, Hartmann E, Jox R, Giese T, Emmerich B, Endres S, Hartmann G.
B cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides.
Clinical Cancer Research 2005; 11:1490-9.
JIF 6.5

 

98. Kerkmann M, Costa LT, Richter C, Rothenfusser S, Battiany J, Hornung V, Johnson J, Englert S, Ketterer T, Heckl W, Thalhammer S, Endres S, Hartmann G.
Spontaneous formation of nucleic acid-based nanoparticles is responsible for high IFN-α induction by CpG-A in plasmacytoid dendritic cells.
Journal of Biological Chemistry 2005; 280:8086-93.
JIF 6.2

 

 

2004

 

97. Hornung V, Schlender J, Guenthner-Biller M, Rothenfusser S, Endres S, Hartmann G.
Replication dependent potent IFN-α induction in human plasmacytoid dendritic cells by a single-stranded RNA virus.
Journal of Immunology 2004; 173:5935-43.
JIF 7.3

 

96. Costa LT, Kerkmann M, Hartmann G, Endres S, Bisch PM, Heckl WM, Thalhammer S.
Structural studies of oligonucleotides containing G-quadruplex motifs using atomic force microscopy.
Biochemical and Biophysical Research Communication 2004; 313:1065-72.
JIF 3.2

 

95. Wagner M, Poeck H, Jahrsdoerfer B, Rothenfusser S, Prell D, Bohle B, Tuma E, Giese T, Ellwart JW, Endres S, Hartmann G.
IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.
Journal of Immunology 2004; 172:954-63.
JIF 7.3

 

94. Poeck H, Wagner M, Battiany J, Rothenfusser S, Wellisch D, Hornung V, Jahrsdorfer B, Giese T, Endres S, Hartmann G.
Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help.
Blood 2004; 103:3058-64.
JIF 10.1

 

93. Rothenfusser S, Hornung V, Ayyoub M, Britsch S, Towarowski A, Krug A, Sarris A, Lubenow N, Speiser D, Endres S, Hartmann G.
CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro.
Blood 2004; 103:2162-9.
JIF 10.1

 

92. Loher F, Bauer C, Landauer N, Schmall K, Siegmund B, Lehr HA, Dauer M, Schoenharting M, Endres S, Eigler A.
The interleukin-1 beta-converting enzyme inhibitor pralnacasan reduces dextran sulfate sodium-induced murine colitis and T helper 1 T-cell activation.
Journal of Pharmacological and Experimental Therapeutics 2004; 308:583-90.
JIF 3.4

 

 

2003

 

91. Obermaier B, Dauer M, Herten J, Schad K, Endres S, Eigler A.
Development of a new protocol for 2-day generation of mature dendritic cells from human monocytes.
Biological Procedures Online 2003; 6:197-203.
JIF 2.0

 

90. Schmidt T, Ziske C, Marten A, Endres S, Tiemann K, Schmitz V, Gorschluter M, Schneider C,      Sauerbruch T, Schmidt-Wolf IG.
Intratumoral immunization with tumor RNA-pulsed dendritic cells confers antitumor immunity in a C57BL/6 pancreatic murine tumor model
Cancer Research 2003; 63:8962-7.
JIF 8.4

 

89. Hartmann E, Wollenberg B, Rothenfusser S, Wagner M, Wellisch D, Mack B, Giese T, Gires O,      Endres S, Hartmann G.
Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer.
Cancer Research 2003; 63:6478-87.
JIF 8.4

 

88. Dauer M, Pohl K, Obermaier B, Meskendahl T, Röbe J, Schnurr M, Endres S, Eigler A.
Interferon-alpha disables dendritic cell precursors: dendritic cells derived from interferon-α-treated monocytes are defective in maturation and T-cell stimulation.
Immunology 2003; 110:38-47.
JIF 2.7

 

87. Hartmann G, Battiany J, Poeck H, Wagner M, Kerkmann M, Lubenow N, Rothenfusser S, Endres S.
Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-α induction in plasmacytoid dendritic cells.
European Journal of Immunology 2003; 33:1633-41.
JIF 5.4

 

86. Kerkmann M, Rothenfusser S, Hornung V, Towarowski A, Wagner M, Sarris A, Giese T, Endres S, Hartmann G.
Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells.
Journal of Immunology 2003; 170:4465-74.
JIF 7.3

 

85. Dauer M, Obermaier B, Herten J, Haerle C, Pohl K, Rothenfusser S, Schnurr M, Endres S, Eigler A.
Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors.
Immunology 2003; 170:4069-76.
JIF 2.7

 

84. Loher F, Schmall K, Freytag P, Landauer N, Hallwachs R, Bauer C, Siegmund B, Rieder F, Lehr HA, Dauer M, Kapp JF, Endres S, Eigler A.
The specific type-4 phosphodiesterase inhibitor mesopram alleviates experimental colitis in mice.
Journal of Pharmacological and Experimental Therapeutics 2003; 305:549-56.
JIF 3.4

 

83. Krug A, Rothenfusser S, Selinger S, Bock C, Kerkmann M, Battiany J, Sarris A, Giese T, Speiser D, Endres S, Hartmann G.
CpG-A oligonucleotides induce a monocyte-derived dendritic cell-like phenotype that preferentially activates CD8 T cells.
Journal of Immunology 2003; 170:3468-77.
JIF 7.3

 

 

2002

 

82. Wollenberg A, Wagner M, Gunther S, Towarowski A, Tuma E, Moderer M, Rothenfusser S, Wetzel S, Endres S, Hartmann G.
Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases.
Journal of Investigative Dermatology 2002; 119:1096-102.
JIF 5.4

 

81. Heckelsmiller K, Rall K, Beck S, Schlamp A, Seiderer J, Jahrsdorfer B, Krug A, Rothenfusser S, Endres S, Hartmann G.
Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model.
Journal of Immunology 2002; 169:3892-9.
JIF 7.3

 

80. Heckelsmiller K, Beck S, Rall K, Sipos B, Schlamp A, Tuma E, Rothenfusser S, Endres S, Hartmann G.
Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors that resist chemotherapy.
European Journal of Immunology 2002; 32:3235-45.
JIF 5.4

 

79. Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, Giese T, Endres S, Hartmann G.
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides.
Journal of Immunology 2002; 7:34-44.
JIF 7.3

 

78. Schnurr M, Scholz C, Rothenfusser S, Galambos P, Dauer M,Röbe J, Endres S, Eigler A.
Apoptotic pancreatic tumor cells are superior to cell lysates in promoting cross-priming of cytotoxic T cells and activate NK and gammadelta T cells.
Cancer Research 2002; 62:2347-52.
JIF 8.4

 

77. Jahrsdorfer B, Jox R, Muhlenhoff L, Tschoep K, Krug A, Rothenfusser S, Meinhardt G, Emmerich B, Endres S, Hartmann G.
Modulation of malignant B cell activation and apoptosis by bcl-2 antisense ODN and immunostimulatory CpG ODN.
Journal of Leukocyte Biology 2002; 72:83-92.
JIF 4.3

 

76. Dauer M, Schulze J, Loher F, Endres S, Eigler A.
Determination of thiopurine S-methyltransferase phenotype using thin-layer chromatography and quantitative scanning.
European Journal of Clinical Pharmacology 2002; 58:41-4.
JIF 1.4

 

75. Zou W, Schwartz H, Endres S, Hartmann G, Bar-Shavit Z.
CpG oligonucleotides: novel regulators of osteoclast differentiation.
FASEB Journal 2002; 16:274-82.
JIF 13.9

 

 

2001

 

74. Howes N, Lerch MM, Mossner J, Endres S, Deviere J, Verreman G, Lucidi V, Charnley R, Imrie C, Hall R, Olah A, Ihse I, Steenbergan W, O'Donnell M, Greenhalf W, Ellis I, Rutherford S, Mountford R, Whitcombe DC, Neoptolemos JP.
High risk of surgical intervention in hereditary pancreatitis.
British Journal of Surgery 2001; 88:475-476.
JIF 2.7

 

73. Rothenfusser S, Hornung V, Krug A, Towarowski A, Krieg A, Endres S, Hartmann G.
Distinct CpG oligonucleotide sequences activate human gd T cells via interferon-a/-b.
European Journal of Immunology 2001; 31:3525-34.
JIF 5.4

 

72. Siegmund B, Rieder F, Lehr H.A, Hartmann G, Dinarello C.A, Endres S, Eigler A.
Neutralization of IL-18 decreases in vivo IFNg synthesis and improves experimental colitis in mice.
American Journal of Physiology 2001; 281:1264-73.
JIF 3.7

 

71. Krug A, Towarowski A, Britsch S, Rothenfusser S, Hornung V, Bahls R, Giese T, Engelmann H, Endres S, Krieg A, Hartmann G.
TLR expression reveals CpG ODN as a unique microbial stimulus for plasmacytoid dendritic cells; synergy with CD40L to induce IL-12p70.
European Journal of Immunology 2001; 31:3026-37.
JIF 5.4

 

70. Siegmund B, Welsch J, Meinhardt G, Emmerich B, Endres S, Eigler A.
Phosphdiesterase type 4 inhibitor suppresses expression of antiapoptotic members of the Bcl-2 family in B-CLL cells and induces Il-10- and caspase-independent apoptosis.
Leukemia 2001; 15:1564-71.
JIF 3.2

 

69. Hacker U, Erhardt S, Tschöp K, Jelinek T, Endres S.
Influence of IL-1RA gene polymorphism on in vivo synthesis of IL-1RA and IL-1β after live yellow fever vaccination.
Experimental and Clinical Immunology 2001; 125:465-69.
JIF 2.7

 

68. Schnurr M, Galambos P, Scholz C, Then F, Dauer M, Endres S, Eigler A.
Tumor cell lysate-pulsed human dendritic cells induce a T cell response against pancreatic carcinoma cells: an in vitro model for the assesment of tumor vaccines.
Cancer Research 2001; 61:6445-50.
JIF 8.4

 

67. Zou W, Hakim I, Tschoep K, Endres S, Bar-Shavit Z.
Tumor necrosis factor-a mediates RANK ligand stimulation of osteoclast differentiation by autocrine mechanism.
Journal of Cellular Biochemistry 2001; 83:70-83.
JIF 2.8

 

66. Krug A, Rothenfusser S, Hornung V, Jahrsdörfer B, Blackwell S, Ballas Z, Endres S, Krieg A, Hartmann G.
A new CpG oligonucleotide sequence induces maximal production of IFN-a in plasmacytoid dendritic cells.
European Journal of Immunology 2001; 31:3026-37.
JIF 5.4

 

65. Tschoep K, Hartmann G, Eigler A, Krug A, Erhardt S, Adams G, Endres S, Delius M.
Shock waves: a novel method for intracytoplasmic delivery of antisense oligonucleotides.
Journal of Molecular Medicine 2001; 79:306-13.
JIF 3.7

 

64. Siegmund B, Albrich S, Rieder F, Wolf K, Firestein GS, Boyle D, Lehr HA, Hartmann G, Endres S, Eigler A.
Adenosine kinase inhibitor GP515 improves experimental colitis in mice.
Journal of Pharmacological and Experimental Therapeutics 2001; 296:1-6.
JIF 3.4

 

63. Jahrsdörfer B, Hartmann G, Racila E, Meinhardt G, Endres S, Krieg AM, Weiner GJ.
CPG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens.
Journal of Leukocyte Biology 2001; 69:81-8.
JIF 4.3

 

 

2000

 

62. Brunner C, Seiderer J, Schlamp A, Bidlingmaier M, Eigler A, Haimerl W, Lehr HA, Krieg A,
Hartmann G, Endres S.
Enhanced dentritic cell maturation by TNF-α or cytidine-phosphate-guanosine DNA drives cell activation in vitro and therapeutic anti-tumor immune responses in vivo.
Journal of Immunology 2000; 165:6278-86.
JIF 7.3

 

61. Schnurr M, Then F, Galambos P, Scholz C, Siegmund B, Endres S, Eigler A.
Extracellular ATP and TNF-α synergize in the acivation and maturation of human dentritic cells.
Journal of Immunology 2000; 165:4704-9.
JIF 7.3

 

60. Eigler A, Matschke V, Hartmann G, Erhardt S, Boyle D, Firestein GS, Endres S.
Suppression of TNF-α production in human mononuclear cells by an adenosine kinase inhibitor.
Journal of Leukocyte Biology 2000; 68:97-103.
JIF 4.3

 

59. Hartmann G, Tschöp M, Bidlingmaier C, Fischer R, Riepl R, Tschöp K, Hautmann H, Endres S, Toepfer M.
High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein.
Cytokine 2000; 12:246-52.
JIF 2.7

 

58. Hartmann G, Bidlingmaier C, Siegmund B, Albrich S, Schulze J, Tschöp K, Eigler A, Lehr HA, Endres S.
The specific type IV phosphodiesterase inhibitor rolipram mitigates experimental colitis in mice.
Journal of Pharmacology and Experimental Therapeutics 2000; 292:22-30.
JIF 3.9

 

57. Tuma E, Eigler A, Toepfer M, Endres S, Schiffl H.
IL-1 receptor antagonist production by isolated mononuclear cells is a better indicator of bioincompatibility of hemodialysis membranes than that by stimulated whole blood.
Nephron 2000; 86:220-221.
JIF 1.9

 

 

1999

 

56. Schulze J, Töpfer M, Schroff K-C, Aschhoff S, Remlen J, Müller-Felber W, Endres S.
Clindamycin and nicotinic neuromuscular transmission (research letter).
The Lancet 1999; 354:1792-93.
JIF 17.9

 

 

1998

 

55. Sinha B, Eigler A, Baumann KH, Greten TF, Moeller J, Endres S.
Nitric oxide downregulates tumour necrosis factor mRNA in Raw 264.7 cells.
Research in Immunology 1998; 149:139-50.
JIF 1.1

 

54. Hartmann G, Bidlingmaier M, Jahrsdörfer B, Krug A, Hacker U, Eigler A, Endres S.
Oligonucleotide uptake in leukocytes is dependent on extracellular calcium: A hint for the involvement of adhesion molecules?
Nucleosides and Nucleotides 1998; 17:1767-73.
JIF 1.0

 

53. Hacker UT, Bidlingmaier C, Gomolka M, Keller E, Eigler A, Hartmann G, Folwaczny C, Fricke H,      Albert E, Loeschke K, Endres S.
Inflammatory bowel diesease: no linkage disequilibrium between allelic polymorphisms of interleukin-1β and IL-1 receptor antagonist genes.
European Journal of Clinical Investigation 1998; 28:214-19.
JIF 2.2

 

52. Siegmund B, Eigler A, Hartmann G, Hacker UT, Endres S.
Adrenaline enhances LPS-induced IL-10 synthesis: evidence for a protein kinase A-mediated pathway.
International Journal of Immunopharmacology 1998; 20:57-69.
JIF 1.0

 

51. Eigler A, Waller-Fontaine K, Moeller J, Hartmann G, Hacker UT, Endres S.
The hairy cell leukemia cell line Eskol spontaneously synthesizes tumor necrosis factor-a and nitric oxide.
Leukemia Research 1998; 22:501-7.
JIF 1.2

 

50. Hartmann G, Krug A, Bidlingmaier M, Hacker UT, Eigler A, Albrecht R, Endres S.
Spontaneous and cationic lipid-mediated uptake of antisense oligonucleotides in human monocytes and lymphocytes.
Journal of Pharmacology and Experimental Therapeutics 1998; 285:920-8.
JIF 3.9

 

49. Eigler A, Siegmund B, Emmerich U, Baumann KH, Hartmann G, Endres S.
Anti-inflammatory activities of cAMP-elevating agents: enhancement of interleukin-10 synthesis and concurrent suppression of tumor necrosis factor production.
Journal of Leukocyte Biology 1998; 63:1-7.
JIF 4.3

 

48. Hacker UT, Jelinek T, Erhardt S, Eigler A, Hartmann G, Endres S.
In vivo synthesis of tumor necrosis factor-a in healthy humans after live yellow fever vaccination.
Journal of Infectious Diseases 1998; 177:774-8.
JIF 5.4

 

 

1997

 

47. Folwaczny C, Fricke H, Endres S, Hartmann G, Spannagl M, Jochum M, Loeschke K.
Anti-inflammatory properties of unfractioned heparin in patients with highly active ulcerative colitis: a pilot study.
American Journal of Gastroenterology 1997; 92:911-2.
JIF 3.2

 

46. Hacker UT, Gomolka M, Keller E, Eigler A, Folwaczny C, Fricke H, Albert E, Loeschke K, Endres S.
Lack of association between a polymorphism in the interleukin-1-receptor-antagonist gene and ulcerative colitis.
Gut 1997; 40:623-7.
JIF 3.0

 

45. Siegmund B, Eigler A, Sinha B, Moeller J, Hartmann G, Endres S.
Suppression of tumor necrosis factor-a production by interleukin-10 is enhanced by cAMP-elevating agents.
European Journal of Pharmacology 1997; 321:231-9.
JIF 2.3

 

44.Eigler A, Greten TF, Sinha B, Haslberger C, Sullivan GW, Endres S.
Endogenous adenosine curtails lipopolysaccharide-stimulated tumor necrosis nactor synthesis.
Scandinavian Journal of Immunology 1997; 45:132-9.
JIF 1.9

 

 

1996

 

43. Müller C, Jelinek T, Endres S, Loeschke K.
Schwere protrahierte Cholestase nach Allgemeinanästhesie bei einer Patientin mit Alagille-Syndrom.
Zeitschrift für Gastroenterologie 1996; 34:809-12.
JIF 1.0

 

42. Hartmann G, Waller-Fontaine K, Eigler A, Moeller J, Krug A, Murphy J, AlbrechtR, Endres S.
Specific suppression of human tumor necrosis factor-a synthesis by antisense oligodeoxynucleotides.
Antisense and Nucleic Acid Drug Development 1996; 6:291-9.
JIF 4.0

 

41. Milani RV, Mandeep RM, Endres S, Eigler A, Cooper ES, Lavie CJ, Ventura HO.
The clinical relevance of circulating tumor necrosis factor-a in acute decompensated chronic heart failure without cachexia.
Chest 1996; 110:992-5.
JIF 1.8

 

40. Hartmann G, Krug A,Waller-Fontaine K, Endres S.
Oligodeoxynucleotides enhance LPS-stimulated synthesis of tumor necrosis factor: Dependence on phosphorothioate modification and reversal by heparin.
Molecular Medicine 1996; 2:429-38.
JIF 4.0

 

39. Greten FT, Moeller J, Feldmeier H, Eigler A, Endres S.
Synthesis of tumour necrosis factor-a in tissue culture of rat coecum: lack of suppression by phosphodiesterase inhibitors.
European Journal of Gastroenterology and Hepatology 1996; 8:679-84.
JIF 0.8

 

38. Greten FT, Sinha B, Haslberger C, Eigler A, Endres S.
Cicaprost and the specific type IV phosphodiesterase inhibitor rolipram synergize in suppression of tumor necrosis factor-a synthesis.
European Journal of Pharmacology 1996; 299:229-33.
JIF 2.3

 

37. Endres S, Whitaker RE, Ghorbani R, Meydani SN, Dinarello CA.
Oral aspirin or ibuprofen increase ex vivo cytokine synthesis.
Immunology 1996; 87:264-70.
JIF 2.9

 

36. Gröttrup-Wolfers E, Moeller J, Karbach U, Müller-Lissner S, Endres S.
Elevated cell-associated levels of interleukin-1β and interleukin-6 in inflamed mucosa of inflammatory bowel disease.
European Journal of Clinical Investigation 1996; 26:115-22.
JIF 2.2

 

 

1995

 

35. Angel JB, Saget BM, Walsh SP, Greten TF, Dinarello CA, Skolnik P, Endres S.
Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication.
AIDS 1995; 9:1137-44.
JIF 6.0

 

34. Greten TF, Eigler A, Sinha B, Moeller J, Endres S.
The specific type IV phosphodiesterase inhibitor rolipram differentially regulates the proinflammatory mediators TNF-α and nitric oxide.
International Journal of Immunopharmacology 1995; 17:605-10.
JIF 1.0

 

33. Eigler A, Moeller J, Endres S.
Exogenous and endogenous nitric oxide attenuates tumor necrosis factor synthesis in the murine macorphage cell line RAW 264.7.
Journal of Immunology 1995; 154:4048-54.
JIF 7.3

 

32. Sinha B, Semmler J, Haen E, Moeller J, Endres S.
Radioimmunoassays for cyclic AMP cross react with phosphodiesterase inhibitors and buffer components.
Journal of Pharmacological and Toxicological Methods 1995; 34:29-36.
JIF 1.1

 

31. Sinha B, Semmler J, Eisenhut T, Eigler A, Endres S.
Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids.
European Journal of Immunology 1995; 25:147-53.
JIF 5.7

 

 

1994

 

30. Endres S, Sinha B, Stoll D, Fülle HJ.
Amrinone suppresses synthesis of tumor necrosis factor by mononuclear cells in vitro.
Shock 1994; 1:377-80.
JIF 1.3

 

29. Siebeck M, Kohl J, Endres S, Spannagl M, Machleidt W.
Delayed treatment with platelet-activating factor receptor antagonist WEB 2086 attenuates pulmonary dysfunction in porcine endotoxin shock.
Journal of Trauma 1994; 37:745-51.
JIF 2.3

 

 

1993

 

28. Eigler A, Sinha B, Endres S.
Nitric oxide-releasing agents enhance cytokine-induced tumor necrosis factor synthesis in human mononuclear cells.
Biochemical and Biophysical Research Communication 1993; 196:494-501.
JIF 3.2

 

27. Endres S, Meydani SN, Ghorbani R, Schindler R, Dinarello CA.
Dietary n-3 fatty acids suppress interleukin‑2 production and mononuclear cell proliferation.
Journal of Leukocyte Biology 1993; 54:599-603.
JIF 4.3

 

26. Eisenhut T, Sinha B, Gröttrup-Wolfers E, Semmler J, Siess W, Endres S.
Prostacyclin analogs suppress the synthesis of tumor necrosis factor-a in LPS-stimulated human peripheral blood mononuclear cells.
Immunopharmacology 1993; 26:259-64.
JIF 1.8

 

25. Semmler J, Wachtel H, Endres S.
The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-a production by human mononuclear cells.
International Journal of Immunopharmacology 1993; 15:409-13.
JIF 1.1

 

24. Semmler J, Gebert U, Eisenhut T, Moeller J, Schönharting MM, Alléra A, Endres S.
Xanthine derivatives: Comparison between suppression of tumour necrosis factor-a production and inhibition of cAMP phosphodiesterase activity.
Immunology 1993; 78:520-5.
JIF 2.9

 

23. Markewitz A, Faist E, Lang S, Endres S, Hültner L, Reichart B.
Regulation of acute phase response after cardiopulmonary bypass by immunomodulation.
The Annals of Thoracic Surgery 1993; 55:389-94.
JIF 1.6

 
 

1992

 

21. Nerad JL, Griffiths JK, van der Meer JWM, Endres S, Poutsiaka DD, Keusch GT, Bennish M, Salam MA, Dinarello CA, Cannon JG.
Interleukin-1β (IL-1β), IL-1 receptor antagonist, and TNFa production in whole blood.
Journal of Leukocyte Biology 1992; 52:200-5.
JIF 3.6

 

20. Ziegler-Heitbrock HWL, Blumenstein M, Käfferlein E, Kieper D, Petersman I, Endres S, Flegel W, Northoff H, Riethmüller G, Haas JG.
In vitro desensitization to LPS suppresses TNF, IL-1 and IL-6 gene expression in a similar fashion.
Immunology 1992; 75:264-8.
JIF 2.8

 

 

1991

 

19. Meydani SN, Endres S, Woods MM, Goldin BR, Soo C, Morrill-Labrode A, Dinarello CA, Gorbach SL.
Oral n-3 fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison in young and older women.
Journal of Nutrition 1991; 121:547-55.
JIF 1.9

 

18. Endres S, Fülle HJ, Sinha B, Stoll D, Dinarello CA, Gerzer R, Weber PC.
Cyclic nucleotides differentially regulate the synthesis of tumor necrosis factor-a and interleukin-1β in human mononuclear cells.
Immunology 1991; 72:56-60.
JIF 2.8

 

 

1990

 

17. Munoz C, Endres S, van der Meer JWM, Schlesinger L, Arevalo M, Dinarello CA.
Interleukin-1β in human collostrum.
Research in Immunology 1990; 141:505-513.
JIF 1.3

 

16. Park MM, Hornback NB, Endres S, Dinarello CA.
The effect of whole body hyperthermia on the immune cell activity of cancer patients.
Lymphokine Research 1990; 9:213-23.
JIF 2.6

 

15. Cannon JG, Tompkins RG, Gelfand JA, Michie HR, Stanford GG, van der MeerJWM, Endres S, Lonneman G, Corsetti J, Chernow B, Wilmore DW, Wolff SM, Burke JF, Dinarello CA.
Circulating interleukin‑1 in septic shock and experimental endotoxin fever.
Journal of Infectious Diseases 1990; 161:79-84.
JIF 4.9

 

14. Schindler R, Mancilla GJ, Endres S, Ghorbani R, Clark SC, Dinarello CA.
Correlation and interaction in the production of IL‑6, IL‑1 and TNF in human blood mononuclear cells: IL‑6 suppresses IL‑1 and TNF.
Blood 1990; 75:40-7.
JIF 8.6

 

 

1989

 

13. Endres S, Cannon JG, Ghorbani R, Dempsey RA, Sisson SD, Lonnemann G, vanderMeerJWM, Wolff SM, Dinarello CA.
In vitro production of IL‑1β, IL-1α, TNF αnd IL‑2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation.
European Journal of Immunology 1989; 19:2327-33.
JIF 6.0

 

12. Lonnemann G, Endres S, van der Meer JWM, Cannon JG, Koch KM, Dinarello CA.
Differences in the synthesis and kinetics of release of interleukin‑1α, interleukin‑1β and tumor necrosis factor from human mononuclear cells.
European Journal of Immunology 1989; 19:1531-6.
JIF 6.0

 

11. Endres S, Ghorbani R, Kelley VE, Georgilis K, Lonnemann G, van der MeerJWM, Cannon JG, Rogers TS, Klempner MS, Weber PC, Schaefer EJ, Wolff SM, DinarelloCA.
The effect of dietary supplementation with n‑3 polyunsaturated fatty acids on the synthesis of interleukin‑1 and tumor necrosis factor by mononuclear cells.
New England Journal of Medicine 1989; 320:265‑71.
JIF 22.4

 

 

1988

 

10. Cannon JG, van der Meer JWM, Kwiatkowski D, Endres S, Lonnemann G, Burke JF, Dinarello CA.
Interleukin-1β in human plasma: Optimization of blood collection, plasma extraction and radioimmunoassay methods.
Lymphokine Research 1988; 7:457‑67.
JIF 2.6

 

9. Okusawa S, Yancey KB, van der Meer JWM, Endres S, Lonnemann L, Hefter K, Frank MM, Burke JF, Dinarello CA, Gelfand JA.
C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro: Comparison with secretion of interleukin-1β and interleukin-1α.
Journal of Experimental Medicine 1988; 168:443‑9.
JIF 15.0

 

8. Endres S, Ghorbani R, Lonnemann G, van der Meer JWM, Dinarello CA.
Measurement of immunoreactive interleukin-1β from human mononuclear cells: optimization of recovery, intrasubject consistency and comparison with interleukin-1α and tumor necrosis factor.
Clinical Immunology and Immunopathology 1988; 49:424‑38.
JIF 2.1

 

7. Lonnemann G, Endres S, van der Meer JWM, Cannon JG, Dinarello CA.
A radioimmunoassay for human interleukin‑1α: Measurement of IL-1α produced in vitro by human blood mononuclear cells stimulated with endotoxin.
Lymphokine Research 1988; 7:75‑85.
JIF 2.6

 

6. Boswell JM, Yui MA, Endres S, Burt DW, Kelley VE.
Novel and enhanced interleukin‑1 gene expression in autoimmune mice with lupus.
Journal of Immunology 1988; 141:118‑24.
JIF 7.4

 

5. Armanini D, Endres S, Kuhnle U, Weber PC.
Parallel determination of mineralocorticoid and glucocorticoid receptors in T‑ and B‑lymphocytes of human spleen.
Acta Endocrinologica 1988; 118:479‑82.
JIF 2.2

 

4. van der Meer JWM, Endres S, Lonnemann G, Cannon JG, Ikejima T, Okusawa S, Gelfand JA, Dinarello CA.
Concentrations of immunoreactive human tumor necrosis factor a produced by human mononuclear cells in vitro.
Journal of Leukocyte Biology 1988; 43:216‑23.
JIF 3.6

 

 

1987

 

3. Okusawa S, Dinarello CA, Yancey KB, Endres S, Lawley TJ, Frank MM, Burke JF, Gelfand JA.
C5a induction of human interleukin-1. Synergistic effect with endotoxin or interferon‑γ.
Journal of Immunology 1987; 139: 2635‑40.
JIF 7.4

 

3. Lisi PJ, Chee‑Wui C, Koch GA, Endres S, Lonnemann G, Dinarello CA.
Development and use of a radioimmunoassay for human interleukin-1β.
Lymphokine Research 1987; 6:229‑44.
JIF 2.6

 

 

1983

 

1. Endres S.
Antigenexpression auf aktivierten T-Lymphozyten.
Dissertation, LMU München 1983;


Doctoral students as co-authors are marked in blue (starting in 1998)